European Journal of Clinical Nutrition最新文献_第9页

The potential renal acid load of plant-based meat alternatives 植物肉类替代品的潜在肾酸负荷

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-19 DOI: 10.1038/s41430-024-01434-8

Julian Herter, Roman Huber, Maximilian Andreas Storz

引用次数: 0

Effects of low-carbohydrate diets, with and without caloric restriction, on inflammatory markers in adults: a systematic review and meta-analysis of randomized clinical trials 低碳水化合物饮食（无论是否限制热量）对成人炎症指标的影响：随机临床试验的系统回顾和荟萃分析

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-18 DOI: 10.1038/s41430-024-01431-x

Fatemeh Kazeminasab, Maryam Miraghajani, Mousa Khalafi, Mohammad Hossein Sakhaei, Sara K. Rosenkranz, Heitor O. Santos

{"title":"Effects of low-carbohydrate diets, with and without caloric restriction, on inflammatory markers in adults: a systematic review and meta-analysis of randomized clinical trials","authors":"Fatemeh Kazeminasab, Maryam Miraghajani, Mousa Khalafi, Mohammad Hossein Sakhaei, Sara K. Rosenkranz, Heitor O. Santos","doi":"10.1038/s41430-024-01431-x","DOIUrl":"10.1038/s41430-024-01431-x","url":null,"abstract":"Low-carbohydrate diets (LCDs) have gained interest due to their favorable effects on health outcomes, such as inflammation. However, further research is needed to ascertain the overall effects of LCDs on inflammatory parameters, but at the same time considering weight loss and calorie intake. Thus, a systematic review and meta-analysis of randomized clinical trials was performed to investigate the effects of LCDs compared with low-fat diets (LFDs), with and without caloric restriction, on inflammatory markers in adults. PubMed, Scopus, and Web of Science were searched through March 2022 to select intervention studies addressing LCDs vs. LFDs, in which the following circulating inflammatory markers were used: C-reactive protein (CRP), tumor necrosis factor alpha (TNF-α), and interleukin (IL-6). Analyses were conducted comparing LCDs vs. LFDs through weighted mean differences (WMD) or standardized mean differences (SMD) and 95% confidence intervals (95% CIs) using random effects models. The systematic review and meta-analysis included a total of 51 studies with a total sample of 4,164 adults, with or without other chronic diseases. Intervention durations ranged from 2–144 weeks. LCDs, compared with LFDs, significantly decreased body weight [WMD = −1.35%, p = 0.001], CRP [SMD = −0.1, p = 0.03], and IL-6 [SMD = −0.15, p = 0.09]. However, LCDs did not significantly decrease TNF-α [SMD = −0.02, p = 0.7] compared to LFDs. In conclusion, LCDs have a beneficial effect on markers of inflammation by decreasing CRP and IL-6; this effect has an association with weight loss. However, LCDs were not more effective than LFDs in decreasing TNF-α.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01431-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140146866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early exposure to sugar sweetened beverages or fruit juice differentially influences adult adiposity 早期接触含糖饮料或果汁会对成年后的脂肪含量产生不同影响。

IF 4.7 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-15 DOI: 10.1038/s41430-024-01430-y

David Benton, Hayley A. Young

{"title":"Early exposure to sugar sweetened beverages or fruit juice differentially influences adult adiposity","authors":"David Benton, Hayley A. Young","doi":"10.1038/s41430-024-01430-y","DOIUrl":"10.1038/s41430-024-01430-y","url":null,"abstract":"To examine associations between different types of sweet drinks consumed in early life and adult adiposity. The analysis involved the secondary analysis of the Avon Longitudinal Study of Parents and Children which followed children from birth to 24 years. Adiposity was measured using Dual-energy X-ray absorptiometry while food frequency questionnaires and diaries monitored diet. ‘Early exposure’ to sweet drinks was defined as giving a sugar-sweetened beverage or 100% fruit juice (FJ), before two years of age. Early exposure to cola was associated with higher fat mass, android fat mass and BMI at age 24 years; whereas early exposure to apple juice was associated with lower adult adiposity in females but not males. When age three, exposure to cola was associated with a greater intake of energy, carbohydrates, protein, fat, and less fruit and more fried foods. In contrast, early exposure to apple juice was associated with higher protein and lower fat intakes and consuming more fruits/vegetables and less fried foods. Parental education, adiposity and socio-economic status influenced whether SSB or FJ was given to a child. Early drinking of sugar sweetened beverages was associated with a less healthy dietary pattern, and greater adult adiposity. Early drinking of apple juice was associated with a healthier dietary pattern, and lower fat mass in adult females. The choice of drink was associated with social deprivation. As the dietary causes of adult obesity begin in early childhood, increased attention should be given to diet in the first years of life.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01430-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of 8-weeks of full versus split body resistance training on appetite and energy intake in non-obese untrained men 8 周全身阻力训练与分身阻力训练对非肥胖未受训练男性的食欲和能量摄入的影响比较。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-14 DOI: 10.1038/s41430-024-01432-w

Larissa Kelly Cardoso, Valéria L. G. Panissa, Jason Micheal Cholewa, Nathanael Leal Santana, Aldeni Silva Brito, Clara Andressa Barros, Esmeralda Maria Lustosa Barros, Rayane Carvalho de Moura, Paula A. Monteiro, Priscila A. Q. Rossi, Matheus Mesquita Vieira, Ahecio Kleber Araujo Brito, João Paulo Jacob Sabino, Nelo Eidy Zanchi, Fabrício Eduardo Rossi

{"title":"Comparison of 8-weeks of full versus split body resistance training on appetite and energy intake in non-obese untrained men","authors":"Larissa Kelly Cardoso, Valéria L. G. Panissa, Jason Micheal Cholewa, Nathanael Leal Santana, Aldeni Silva Brito, Clara Andressa Barros, Esmeralda Maria Lustosa Barros, Rayane Carvalho de Moura, Paula A. Monteiro, Priscila A. Q. Rossi, Matheus Mesquita Vieira, Ahecio Kleber Araujo Brito, João Paulo Jacob Sabino, Nelo Eidy Zanchi, Fabrício Eduardo Rossi","doi":"10.1038/s41430-024-01432-w","DOIUrl":"10.1038/s41430-024-01432-w","url":null,"abstract":"To investigate the effects of 8-weeks of full versus split body resistance training (RT) on appetite and energy intake in non-obese untrained men. The participants were pair-matched based on their initial fat mass and then randomly allocated into one of two treatment groups: Full body (FB, n = 20), in which all muscle groups were trained in every session, or Split body (SB, n = 15), in which upper and lower muscle groups were trained alternated per session; both groups trained in non-consecutive days, three times per week with total number of sets performed equated between groups. Energy intake, body composition, and strength performance were evaluated at pre-training, and after 8-weeks of RT, as well as self-reported hunger, fullness, and desire to eat, that were assessed at fasted and feed states pre- and post-intervention. FB and SB resistance training increased fat-free mass (FFM) (p < 0.001); and FB induced greater maximal strength improvement (p = 0.027). At fasted state self-reported hunger increased, and fullness decreased, while in feed state desire to eat something fatty increased in both groups. Carbohydrate intake (p = 0.011) decreased in both groups. In conclusion, FB and SB training increased orexigenic drive (increasing hunger and decreasing fullness), however, total energy intake and fat mass did not change after 8-weeks of RT in non-obese untrained men. Registered under Brazilian Registry of Clinical Trials no. RBR-3wkcvyw.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140131092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dichotomous effect of dietary fiber in pediatrics: a narrative review of the health benefits and tolerance of fiber 儿科膳食纤维的二分法效应：关于纤维对健康的益处和耐受性的叙述性综述。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-13 DOI: 10.1038/s41430-024-01429-5

Nandini Basuray, Edward C. Deehan, Flávio T. Vieira, Hayford M. Avedzi, Reena L. Duke, Eloisa Colín-Ramírez, Hein M. Tun, Zhengxiao Zhang, Eytan Wine, Karen L. Madsen, Catherine J. Field, Andrea M. Haqq

{"title":"Dichotomous effect of dietary fiber in pediatrics: a narrative review of the health benefits and tolerance of fiber","authors":"Nandini Basuray, Edward C. Deehan, Flávio T. Vieira, Hayford M. Avedzi, Reena L. Duke, Eloisa Colín-Ramírez, Hein M. Tun, Zhengxiao Zhang, Eytan Wine, Karen L. Madsen, Catherine J. Field, Andrea M. Haqq","doi":"10.1038/s41430-024-01429-5","DOIUrl":"10.1038/s41430-024-01429-5","url":null,"abstract":"Dietary fibers are associated with favorable gastrointestinal, immune, and metabolic health outcomes when consumed at sufficient levels. Despite the well-described benefits of dietary fibers, children and adolescents continue to fall short of daily recommended levels. This gap in fiber intake (i.e., “fiber gap”) might increase the risk of developing early-onset pediatric obesity and obesity-related comorbidities such as type 2 diabetes mellitus into adulthood. The structure-dependent physicochemical properties of dietary fiber are diverse. Differences in solubility, viscosity, water-holding capacity, binding capability, bulking effect, and fermentability influence the physiological effects of dietary fibers that aid in regulating appetite, glycemic and lipidemic responses, and inflammation. Of growing interest is the fermentation of fibers by the gut microbiota, which yields both beneficial and less favorable end-products such as short-chain fatty acids (e.g., acetate, propionate, and butyrate) that impart metabolic and immunomodulatory properties, and gases (e.g., hydrogen, carbon dioxide, and methane) that cause gastrointestinal symptoms, respectively. This narrative review summarizes (1) the implications of fibers on the gut microbiota and the pathophysiology of pediatric obesity, (2) some factors that potentially contribute to the fiber gap with an emphasis on undesirable gastrointestinal symptoms, (3) some methods to alleviate fiber-induced symptoms, and (4) the therapeutic potential of whole foods and commonly marketed fiber supplements for improved health in pediatric obesity.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140119175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between body mass index and age of disease onset with clinical outcomes in paediatric-onset Crohn’s Disease (CD): a UK nation-wide analyses using the NIHR-IBD BioResource 儿科克罗恩病 (CD) 患者体重指数和发病年龄与临床结果之间的关系：利用 NIHR-IBD 生物资源进行的英国全国性分析。

IF 4.7 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-12 DOI: 10.1038/s41430-024-01425-9

Bayan Aljilani, Kostas Tsintzas, Mario Siervo, Gordon W. Moran

{"title":"Association between body mass index and age of disease onset with clinical outcomes in paediatric-onset Crohn’s Disease (CD): a UK nation-wide analyses using the NIHR-IBD BioResource","authors":"Bayan Aljilani, Kostas Tsintzas, Mario Siervo, Gordon W. Moran","doi":"10.1038/s41430-024-01425-9","DOIUrl":"10.1038/s41430-024-01425-9","url":null,"abstract":"The evidence on the relationship between adiposity and disease outcomes in paediatric Crohn’s disease (CD) is limited and lacks consensus. To investigate the relationship between (a) body mass index (BMI) and clinical CD outcomes (hospitalisation, surgery, disease behaviour, biologic use, extra-intestinal manifestations (EIMs)) and (b) the age of CD onset with clinical outcomes. Clinical outcomes were examined in CD patients diagnosed at age <17 years and enroled in the National Institute for Health Research IBD-UK BioResource at a median age of 24 years. All outcomes and BMI were recorded at the time of enrolment. Participants were categorised into normal (<25 kg/m2) and high (≥25 kg/m2) BMI. Age at disease diagnosis was categorised into pre-puberty/early puberty (<11 years), puberty (11–14 years) and post-puberty (15–17 years). Spearman rank correlation was used to test the associations between continuous variables and chi-square test to compare categorical variables. 848 participants with CD were included (51.8% males) and median age at diagnosis was 14 years. Participants with high BMI experienced a greater frequency of EIMs (P = 0.05) than those with low BMI (1 type of EIM: 18.5% vs. 13.2%, respectively; ≥2 types of EIMs: 7.8% vs. 5.6%, respectively). Age at diagnosis and BMI showed weak correlations with corticosteroid use (ρ = 0.08, P = 0.03 and ρ = −0.09, P = 0.01; respectively). An early diagnosis (<11 years) was associated with higher occurrence of stenosing and penetrating disease behaviour (P = 0.01) and hospitalisations (P < 0.001). A higher BMI and an earlier age of disease onset are associated with worse CD clinical presentation.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01425-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140109720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional status of infants and young children in India across three decades: Analysis of five national family health surveys 三十年来印度婴幼儿的营养状况：对五次全国家庭健康调查的分析。

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-11 DOI: 10.1038/s41430-024-01427-7

Ramendra Nath Kundu, Rajesh K. Gautam, Arna Chatterjee, Premananda Bharati, Grażyna Liczbińska, Robert M. Malina

{"title":"Nutritional status of infants and young children in India across three decades: Analysis of five national family health surveys","authors":"Ramendra Nath Kundu, Rajesh K. Gautam, Arna Chatterjee, Premananda Bharati, Grażyna Liczbińska, Robert M. Malina","doi":"10.1038/s41430-024-01427-7","DOIUrl":"10.1038/s41430-024-01427-7","url":null,"abstract":"Three indicators of early childhood undernutrition and associated factors are evaluated among under-5 children in five National Family Health Surveys in India spanning 1992 to 2021. Data for 533,495 children under 5 years of age (U–5) were analysed in the context of three commonly used indicators of early childhood undernutrition – wasting, stunting and underweight. In addition to descriptive and inferential statistics, binary logistic regression was used to estimate the effects of specific explanatory factors on the three indicators using adjusted odds ratios. Over the three-decade interval, stunting was reduced by 22.1% in boys and 20.9% in girls, followed by underweight, 19.3% in boys and 17.4% in girls; wasting, in contrast, was reduced to a considerably lesser extent, 2.8% in boys and 0.9% in girls. Demographic, maternal and socioeconomic factors were associated with the incidence of early childhood undernutrition, specifically among young mothers and those with less education in low-income families, and among children from Scheduled Tribes or Scheduled Castes. Stunting and underweight declined significantly over the past three decades while wasting changed negligibly. The disparity in the occurrence of early childhood undernutrition was apparent throughout socioeconomic categories and regions of India. The results highlight the need for special programs aimed at reducing waste among children and also the need for customized initiatives focused on the improvement of maternal education and wealth in addition to other ancillary factors related to regional variation.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study 动物双歧杆菌亚种乳杆菌 BLa80 治疗儿童急性腹泻的疗效判断：一项随机、双盲、安慰剂对照研究

IF 4.7 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-11 DOI: 10.1038/s41430-024-01428-6

Ke Chen, Shanshan Jin, Yu Ma, Limei Cai, Ping Xu, Yang Nie, Li Luo, Qinghua Yu, Yang Shen, Zengyuan Zhou, Changqi Liu

{"title":"Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study","authors":"Ke Chen, Shanshan Jin, Yu Ma, Limei Cai, Ping Xu, Yang Nie, Li Luo, Qinghua Yu, Yang Shen, Zengyuan Zhou, Changqi Liu","doi":"10.1038/s41430-024-01428-6","DOIUrl":"10.1038/s41430-024-01428-6","url":null,"abstract":"The goal of this study is to assess the efficacy and safety of Bifidobacterium animalis subsp. lactis BLa80, as an adjunct treatment for diarrhea in children with a randomized, double-blinded, placebo-controlled study design. Eligible diarrheal children, aged 0–3 years without the need for antibiotic treatment based on clinical diagnosis when recruited, were randomized into the intervention group (IG, n = 58, with probiotic) or the control group (CG, n = 53, placebo). The primary assessment was the duration of diarrhea. Fecal samples were collected for biochemical index measurement, analysis of gut microbiome composition, and prediction of gene family abundances. The total duration of diarrhea in the IG (122.6 ± 13.1 h) was significantly shorter than in the CG (148.4 ± 17.6 h, p < 0.001). More children in the IG showed improvements in diarrhea compared to the CG, both in intention-to-treat analysis (81.7% vs. 40.0%, p < 0.001) and per protocol analysis (84.4% vs 45.3%, p < 0.001). Cathelicidin level in the IG was significantly higher than that in the CG after the intervention (4415.00 ± 1036.93 pg/g vs. 3679.49 ± 871.18 pg/g, p = 0.0175). The intervention led to an increased abundance of Bifidobacterium breve and Collinsella aerofaciens species, higher alpha-diversity (p < 0.05), and enrichment of functional genes in the gut microbiota related to immunity regulation. Administration of BLa80 at a dose of 5 × 109 CFU/day resulted in a shorter duration of diarrhea and alterations in gut microbiome composition and gene functions.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01428-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140099830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mediterranean-style dietary interventions in adults with cancer: a systematic review of the methodological approaches, feasibility, and preliminary efficacy 对成人癌症患者进行地中海式饮食干预：对方法、可行性和初步疗效的系统回顾。

IF 4.7 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-08 DOI: 10.1038/s41430-024-01426-8

Aoife McHugh, Ellie O’Connell, Bridie Gurd, Paige Rae, Elena S. George, Amber S. Kleckner, Brenton J. Baguley

{"title":"Mediterranean-style dietary interventions in adults with cancer: a systematic review of the methodological approaches, feasibility, and preliminary efficacy","authors":"Aoife McHugh, Ellie O’Connell, Bridie Gurd, Paige Rae, Elena S. George, Amber S. Kleckner, Brenton J. Baguley","doi":"10.1038/s41430-024-01426-8","DOIUrl":"10.1038/s41430-024-01426-8","url":null,"abstract":"Cancer and its treatments can lead to excess body fat, decreases in lean mass, cardiotoxicity, and other side effects. The Mediterranean diet (MED-diet) has the potential to improve clinical and supportive care outcomes. The aim of this systematic review was to evaluate the feasibility, safety, and efficacy of the MED-diet on health outcomes in adults with cancer. Three databases were searched from inception to February 2023. Eligible studies included randomised controlled trials testing a MED-diet intervention among adults with cancer. Within- and between-group differences for adherence, dietary intake and health outcomes were extracted. Fifteen studies describing fourteen interventions were included, and there were considerable differences in study design and implementation of the MED-diet. Studies were predominately in women with a history of breast cancer. The MED-diet was safe with no adverse events reported, and feasible with high adherence and/or increases in MED-diet-compliant foods. The MED-diet when applied with an energy restriction below estimated requirements for weight loss demonstrated reductions in body weight (range: −3.9 kg to −0.7 kg). Interventions that showed significant reductions in body weight also improved quality of life. There is limited evidence to evaluating the MED-diet on cardiovascular and inflammatory markers, and heterogenous MED-diet prescriptions impede definitive conclusions on these health outcomes. The MED-diet was feasible and safe for adults with cancer. There were reported benefits for weight loss following a MED-diet when an energy restriction was applied, however further evaluation to determine the effects on cardiometabolic biomarkers and other outcomes are required.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":4.7,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01426-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does minimed 780GTM insulin pump system affect energy and nutrient intake?: long-term follow-up study minimed 780GTM 胰岛素泵系统是否影响能量和营养素的摄入？

IF 3.6 3区医学

European Journal of Clinical Nutrition Pub Date : 2024-03-08 DOI: 10.1038/s41430-024-01422-y

Yasemin Atik-Altinok, Yelda Mansuroglu, Gunay Demir, Hanife Gul Balki, Samim Ozen, Sukran Darcan, Damla Goksen

{"title":"Does minimed 780GTM insulin pump system affect energy and nutrient intake?: long-term follow-up study","authors":"Yasemin Atik-Altinok, Yelda Mansuroglu, Gunay Demir, Hanife Gul Balki, Samim Ozen, Sukran Darcan, Damla Goksen","doi":"10.1038/s41430-024-01422-y","DOIUrl":"10.1038/s41430-024-01422-y","url":null,"abstract":"We evaluate the energy and nutrient intake of children, adolescents, and young adults with type 1 diabetes (T1D) who started to use automated insulin delivery (AID) systems before the transition and during follow-up for 6 months in a real-world setting. Twenty-nine people with T1D (PwD) who started to use MiniMed 780GTM participated in the study. Participants’ 3-day food diaries and glycemic outcomes were analyzed at baseline and after (the 3rd and 6th month) switching to an advanced hybrid closed-loop system (a-HCL). Mean carbohydrate, protein, and fat intake (energy %) at baseline were 49.1 ± 4.5, 17.8 ± 2.3, and 33.0 ± 3.9, respectively, and there were no statistically significant differences during the follow-up period. However, low fiber (<14 g/1000 kcal) and high saturated fat (>10 energy %) intake in PwD, both baseline and follow-up period. The median auto-correction bolus ratio was 14.0 (9.5)% at auto mode after 14 days, 18.0 (11.0)% at the 3rd month, and 19.0 (7.5)% at the 6th month (p < 0.05). A negative correlation was present between auto-correction boluses with TIR in both the 3rd (r:-0.747, p < 0.01) and 6th month (r:-0.395, p < 0.05). A negative correlation was present between auto-correction boluses with TIR in both the 3rd (r:-0.747, p < 0.01) and 6th month (r:-0.395, p < 0.05). a-HCLS systems offer better glycemic control. Using the Minimed 780 GTM insulin pump system didn’t change the energy and nutrient intake of PwD. This real-world follow-up study suggests that children, adolescents, and young adults with T1D consume saturated fat above and fiber intake lower than recommendations independent of the use of a-HCLS. NCT05666596.","PeriodicalId":11927,"journal":{"name":"European Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":3.6,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41430-024-01422-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0