{"title":"Reply to: PHOENICS trial: robust methods, outdated question and can PHOENICS resurrect hydroxyethyl starch? A cautious view.","authors":"Wolfgang Buhre","doi":"10.1097/EJA.0000000000002407","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002407","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"554-555"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Damien A Hughes, Malcolm A Broom, Victoria A Eley, Andrea Melber, Yavor Metodiev, Kirsty Maclennan, Shalini Sundaram, Marc Van de Velde, Philip Anderson, Nuala Lucas
{"title":"Remifentanil patient-controlled analgesia for labour analgesia: guidance from the obstetric anaesthetists' association: Recommendations for well tolerated provision of remifentanil PCA for labour analgesia.","authors":"Damien A Hughes, Malcolm A Broom, Victoria A Eley, Andrea Melber, Yavor Metodiev, Kirsty Maclennan, Shalini Sundaram, Marc Van de Velde, Philip Anderson, Nuala Lucas","doi":"10.1097/EJA.0000000000002373","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002373","url":null,"abstract":"<p><strong>Background: </strong>Remifentanil patient-controlled analgesia (PCA) has emerged as an important option for labour analgesia, particularly for women who are unable to receive neuraxial analgesia. Concerns about maternal safety and staffing requirements suggest that in many maternity units, it is only infrequently used, leading to variation in practice. In 2023, the UK National Institute for Health and Care Excellence recommended that all labouring women be informed about the full range of analgesia options, including remifentanil PCA, highlighting the need for a standardised management approach.</p><p><strong>Methods: </strong>To address these challenges, the Obstetric Anaesthetists' Association convened an expert working group to develop evidence-based guidance. The group undertook a review of the literature, and used a modified Delphi approach to create consensus statements and recommendations. Recommendations were developed based on the evidence. Where evidence was insufficient to support recommendations, statements were provided with an associated level of certainty. These recommendations aim to support clinicians in providing well tolerated, effective and patient-centred care when using remifentanil PCA for labour analgesia. Statements and recommendations are graded according to the US Preventive Services Task Force grading methodology, ensuring transparency and robustness in the development process.</p><p><strong>Results: </strong>A total of 757 articles were identified in the initial literature search. Further screening identified 83 full text articles of relevance. A structured narrative review was produced which covered patient suitability for remifentanil PCA (maternal and foetal factors), practical use of remifentanil PCA, standards of care for women receiving remifentanil PCA and quality assurance and monitoring. The working party agreed on 19 recommendations and six statements. These were generally assigned a low or moderate level of certainty. The safety of mother and baby were the key priorities in producing these guidelines.</p><p><strong>Conclusions: </strong>Remifentanil PCA can provide effective labour analgesia, particularly when neuraxial techniques are contraindicated or declined. Despite some inherent risks, when managed within defined parameters, there is now an established record of efficacy and safety. It is essential that labour wards have clear protocols for administration and monitoring, and for staff to be trained in recognising and managing complications. There is a lack of data for remifentanil PCA use in higher-risk maternal and foetal groups; this is an area of research priority. These first evidence-based guidelines aim to standardise care and support the well tolerated and effective use of remifentanil PCA in labour.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"486-498"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing the association between postpartum depression and caesarean section under general anaesthesia.","authors":"Zhi-Yu Geng, Lin-Lin Song","doi":"10.1097/EJA.0000000000002388","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002388","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"563-564"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philippe Laitselart, Marion Antonini, Matthieu Laurent, François Guiouillier, Jean Derely, Nicolas Donat
{"title":"The impact of intra-operative norepinephrine on free flap survival: A propensity score-matched retrospective study.","authors":"Philippe Laitselart, Marion Antonini, Matthieu Laurent, François Guiouillier, Jean Derely, Nicolas Donat","doi":"10.1097/EJA.0000000000002376","DOIUrl":"10.1097/EJA.0000000000002376","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"537-539"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147347885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Fuchs, Charlotte Backhauss, Lea Franzmeier, Claudio Bonesana, Daniele Malpetti, Lea Ruscher, Markus Huber, Thomas Riva, Laura Azzimonti, Robert Greif
{"title":"HEAVEN criteria to predict difficult in-hospital rapid sequence intubation: a prospective single-centre observational study.","authors":"Alexander Fuchs, Charlotte Backhauss, Lea Franzmeier, Claudio Bonesana, Daniele Malpetti, Lea Ruscher, Markus Huber, Thomas Riva, Laura Azzimonti, Robert Greif","doi":"10.1097/EJA.0000000000002382","DOIUrl":"10.1097/EJA.0000000000002382","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"550-553"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13152049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147364413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to: ultrasonographic assessment of sugammadex-enhanced early recovery of diaphragmatic function in children.","authors":"Jung-Bin Park, Ji-Hyun Lee","doi":"10.1097/EJA.0000000000002385","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002385","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"558-559"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Caution is warranted when interpreting the association of perioperative fluid balance and acute kidney injury in patients undergoing elective colorectal surgery.","authors":"Keqin Zhang, Tianxiang Gao, Rui Bao, Wenbin Lu","doi":"10.1097/EJA.0000000000002401","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002401","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"556"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Vetter, Kathleen Seidel, David Bervini, Vladimir Krejci
{"title":"Reply to: considerations for dexmedetomidine as a propofol-sparing agent.","authors":"Christian Vetter, Kathleen Seidel, David Bervini, Vladimir Krejci","doi":"10.1097/EJA.0000000000002374","DOIUrl":"https://doi.org/10.1097/EJA.0000000000002374","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"43 6","pages":"556-557"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean-Luc Fellahi, Emmanuel Futier, Bernard Cholley, Matthias Jacquet-Lagreze
{"title":"Pro: we should fully utilise the preload reserve in high-risk patients undergoing noncardiac surgery.","authors":"Jean-Luc Fellahi, Emmanuel Futier, Bernard Cholley, Matthias Jacquet-Lagreze","doi":"10.1097/EJA.0000000000002383","DOIUrl":"10.1097/EJA.0000000000002383","url":null,"abstract":"<p><p>In high-risk surgical patients undergoing noncardiac procedures, volume expansion through the titrated administration of small fluid challenges following anaesthesia induction does not lead to excessive cumulative fluid balance compared to standard care. This strategy may contribute to the prevention of haemodynamic instability and occult hypoperfusion, especially within critical vascular beds. In this context, the French guidelines recommend the prophylactic optimisation of stroke volume through titrated fluid administration as a physiologically justified and clinically appropriate practice that should be routinely adopted by anaesthesiologists in the operating room.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"499-502"},"PeriodicalIF":6.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}