{"title":"Reply to: videolaryngoscopy in neonates is not a matter of perspective.","authors":"Tom G Hansen, Laszlo Vutskits","doi":"10.1097/EJA.0000000000002147","DOIUrl":"10.1097/EJA.0000000000002147","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"42 4","pages":"372-373"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaime Andres Arias, Gustavo Roberto Minetto Wegner, Bruno Francisco Minetto Wegner, Larissa Santos Silva, Francisco José Lucena Bezerra, Rafaela Goes Machado Filardi
{"title":"Association of remimazolam with delirium and cognitive function: A systematic review and meta-analysis of randomised controlled trials.","authors":"Jaime Andres Arias, Gustavo Roberto Minetto Wegner, Bruno Francisco Minetto Wegner, Larissa Santos Silva, Francisco José Lucena Bezerra, Rafaela Goes Machado Filardi","doi":"10.1097/EJA.0000000000002107","DOIUrl":"10.1097/EJA.0000000000002107","url":null,"abstract":"<p><strong>Background and study objective: </strong>Delirium is an organic mental syndrome significantly associated with long-term cognitive decline, increased hospital stays and higher mortality. This systematic review of randomised controlled trials (RCTs) with meta-analysis assesses the association of remimazolam with postoperative cognitive function and delirium compared with non-benzodiazepine hypnotics.</p><p><strong>Design: </strong>Systematic review of RCTs with meta-analysis.</p><p><strong>Data sources: </strong>PubMed, Embase, Cochrane Library and Web of Science databases up to 27 April 2024.</p><p><strong>Eligibility criteria: </strong>Adult patients undergoing general anaesthesia or sedation procedures; use of remimazolam as the primary hypnotic or as an adjunct, administered via intermittent bolus or continuous infusion; comparison with other hypnotics or sedatives; evaluation of cognitive function or delirium.</p><p><strong>Main results: </strong>Twenty-three RCTs with 3598 patients were included. The incidence of delirium was not significantly different between remimazolam and other sedatives in general anaesthesia and sedation procedures [ n = 3261; odds ratio (OR) = 1.2, 95% confidence interval (CI), 0.76 to 1.91; P = 0.378843; I2 = 17%]. Regarding cognitive function evaluation, remimazolam showed no difference compared with the control group in Mini-Mental State Examination (MMSE) scores on the first postoperative day ( n = 263; mean difference = 0.60, 95% CI, -1.46 to 2.66; P = 0.5684; I2 = 90%) or on the third postoperative day ( n = 163; mean difference = 1.33, 95% CI, -0.72 to 3.38; P = 0.2028; I2 = 93%). Remimazolam exhibited superiority over the control group in MMSE scores on the seventh postoperative day ( n = 247; mean difference = 0.53, 95% CI, 0.30 to 0.75; P < 0.0001; I2 = 28%).</p><p><strong>Conclusion: </strong>Remimazolam does not increase the incidence of delirium or cognitive impairments compared with non-benzodiazepine hypnotics. However, the analysis showed that the type of surgery significantly influenced the incidence of delirium. Additionally, remimazolam was associated with better short-term postoperative cognitive function.</p><p><strong>Systematic review registration: </strong>PROSPERO CRD42024532751.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"285-297"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma G Sampson, Sathish Ramanathan, Kenichi A Tanaka, Amir L Butt
{"title":"The risks we miss: Accounting for demographic and surgical variability in anaemia studies.","authors":"Emma G Sampson, Sathish Ramanathan, Kenichi A Tanaka, Amir L Butt","doi":"10.1097/EJA.0000000000002139","DOIUrl":"10.1097/EJA.0000000000002139","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"42 4","pages":"378-379"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parineeta Ghosh, Patrick A Ward, Jane L Orrock, Robert Greif, Alistair F McNarry
{"title":"A safety checklist for apnoeic oxygenation using high-flow nasal oxygen for laryngotracheal surgery in adults: An international Delphi consensus.","authors":"Parineeta Ghosh, Patrick A Ward, Jane L Orrock, Robert Greif, Alistair F McNarry","doi":"10.1097/EJA.0000000000002128","DOIUrl":"10.1097/EJA.0000000000002128","url":null,"abstract":"<p><strong>Background: </strong>Apnoeic oxygenation using high-flow nasal oxygen is becoming a commonly used technique in adult patients undergoing laryngotracheal surgery. Despite widespread adoption, there are no best practice guidelines governing its safe delivery.</p><p><strong>Objective: </strong>To develop a checklist for use during laryngotracheal surgery to guide the safe delivery of apnoeic oxygenation using high-flow nasal oxygen.</p><p><strong>Design: </strong>Recognised experts in the field of apnoeic oxygenation were invited to participate in a Delphi process to establish essential items for inclusion in the safety checklist. An online Delphi survey platform was used to facilitate this process.</p><p><strong>Setting: </strong>A panel of 36 experts was assembled from 11 countries. They participated voluntarily in an 8-week Delphi process that included one preliminary round, two electronic voting rounds and a final virtual roundtable discussion. A small steering group was responsible for leading the Delphi process, collating the electronic voting responses, analysing the results and compiling the final checklist.</p><p><strong>Main outcome measures: </strong>The consensus threshold for inclusion/exclusion of items in the safety checklist was set at at least 80% for the first and second electronic voting rounds. The consensus threshold was set at 70% for the final roundtable discussion.</p><p><strong>Results: </strong>The final checklist comprises 19 items, sub-divided into pre-procedure, peri-procedure and post-procedure aspects of patient care. The Delphi process was well attended, with an expert attrition rate of only 6%. A number of items reached more than 90% consensus, including the requirement to establish patients' suitability for the technique in advance of surgery and preparedness for the immediate implementation of an agreed individualised rescue oxygenation strategy.</p><p><strong>Conclusion: </strong>A Delphi process involving international experts has formulated a 19-item checklist for guiding the safe delivery of apnoeic oxygenation using high-flow nasal oxygen in adult patients undergoing laryngotracheal surgery. Further studies are required to assess the effects of this checklist on patient safety and outcomes.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"357-365"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Taner Abdullah, Hürü Ceren Gökduman, Achmet Ali, Funda Gümüş Özcan
{"title":"Reply to comments on: mean arterial pressure versus cardiac index for haemodynamic management and myocardial injury after hepatopancreatic surgery.","authors":"Taner Abdullah, Hürü Ceren Gökduman, Achmet Ali, Funda Gümüş Özcan","doi":"10.1097/EJA.0000000000002125","DOIUrl":"10.1097/EJA.0000000000002125","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"42 4","pages":"375-377"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Á Gómez-Ríos, Miguel Á Fernández-Vaquero, André A J Van Zundert
{"title":"A call for standardised videolaryngoscopy evaluation.","authors":"Manuel Á Gómez-Ríos, Miguel Á Fernández-Vaquero, André A J Van Zundert","doi":"10.1097/EJA.0000000000002129","DOIUrl":"10.1097/EJA.0000000000002129","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"42 4","pages":"380-381"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Britta S von Ungern-Sternberg, James Peyton, Clyde Matava
{"title":"Videolaryngoscopy in neonates is not a matter of perspective.","authors":"Britta S von Ungern-Sternberg, James Peyton, Clyde Matava","doi":"10.1097/EJA.0000000000002117","DOIUrl":"10.1097/EJA.0000000000002117","url":null,"abstract":"","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":"42 4","pages":"371-372"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sander F van den Heuvel, Philip Jonker, Sanne E Hoeks, Sohal Y Ismail, Robert Jan Stolker, Jan-Wiebe H Korstanje
{"title":"The effect of stand-alone and additional preoperative video education on patients' knowledge of anaesthesia: A randomised controlled trial.","authors":"Sander F van den Heuvel, Philip Jonker, Sanne E Hoeks, Sohal Y Ismail, Robert Jan Stolker, Jan-Wiebe H Korstanje","doi":"10.1097/EJA.0000000000002109","DOIUrl":"10.1097/EJA.0000000000002109","url":null,"abstract":"<p><strong>Background: </strong>Fully digital preoperative information could save valuable time and resources. However, compared with face to face consultations, equivalent levels of safety, patient satisfaction and participation need to be maintained when using other methods to inform patients. This trial compared knowledge retention between preoperative stand-alone video education and face-to-face education by an anaesthesiologist.</p><p><strong>Objectives: </strong>To assess if video education, alone or combined with face-to-face education, leads to better knowledge retention more than conventional face-to-face education.</p><p><strong>Design: </strong>A randomised controlled trial with four arms: Video, Anaesthesiologist, Video & Anaesthesiologist, and Reference for baseline measurements and exploration of a test-enhanced learning effect.</p><p><strong>Setting: </strong>A Dutch tertiary care centre from February 2022 to February 2023.</p><p><strong>Patients: </strong>A total of 767 adult patients undergoing preoperative consultation for elective non-cardiothoracic surgery, with 677 included in the complete case analysis.</p><p><strong>Interventions: </strong>Stand-alone preoperative video education and video education in combination with face-to-face education in the preoperative outpatient clinic.</p><p><strong>Main outcome measures: </strong>Primary outcome, measured by the Rotterdam Anaesthesia Knowledge Questionnaire, was knowledge retention on day 0. Secondary outcomes included knowledge retention at 14 and 42 days, preoperative anxiety, and the need for additional information using the Amsterdam Preoperative Anxiety and Information Scale. Other outcomes were satisfaction, self-assessed knowledge, and test-enhanced learning effect.</p><p><strong>Results: </strong>Stand-alone video education led to higher Rotterdam Anaesthesia Knowledge Questionnaire scores than face-to-face education on day 0: median [IQR], 87.5 [81.3 to 93.8] vs. 81.3 [68.8 to 87.5], P < 0.001. Combined education in the \"Video & Anaesthesiologist\" group led to better knowledge retention compared with both the \"Anaesthesiologist\" group and the Video group: 93.8 [87.5 to 93.8] vs. 81.3 [68.8 to 87.5], P < 0.001; 93.8 [87.5 to 93.8] vs. 87.5 [81.3 to 93.8], P = 0.01, respectively. No differences in the patients' preoperative anxiety and satisfaction levels were found.</p><p><strong>Conclusion: </strong>Compared with face-to-face education by an anaesthesiologist, stand-alone video and combined video education improve short-term knowledge retention, without increasing patient anxiety.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT05188547.</p>","PeriodicalId":11920,"journal":{"name":"European Journal of Anaesthesiology","volume":" ","pages":"313-323"},"PeriodicalIF":4.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11872255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}