European Heart Journal: Case Reports最新文献_第9页

Purulent pericarditis caused by Streptococcus pyogenes: a case report and review. 化脓链球菌所致化脓性心包炎1例报告及复习。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-04-03 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf156

Vincenzo Somma, Adam Trytell, Andrew MacIsaac

{"title":"Purulent pericarditis caused by Streptococcus pyogenes: a case report and review.","authors":"Vincenzo Somma, Adam Trytell, Andrew MacIsaac","doi":"10.1093/ehjcr/ytaf156","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf156","url":null,"abstract":"Background: Purulent pericarditis is rare and associated with significant mortality. We outline a case of Group A streptococcus (GAS, Streptococcus pyogenes) native aortic valve infective endocarditis with associated purulent pericarditis and review the literature. Of the reported cases, most occur in children and have high degrees of mortality. There are no cases that describe GAS purulent pericarditis as a complication of infective endocarditis.Case summary: A 43-year-old female presented with an altered conscious state and refractory hypotension. An urgent transthoracic echocardiogram revealed a vegetation on the aortic valve, moderate-severe aortic regurgitation and a moderate-large circumferential pericardial effusion with evidence of early cardiac tamponade. An urgent pericardiocentesis was performed and drained 500 mL of purulent pericardial fluid. Peripheral blood and pericardial fluid cultures grew GAS. Unfortunately the pericardiocentesis did not improve the patient's haemodynamics, she developed recurrent malignant arrhythmias culminating in cardiac arrest and was unable to be resuscitated.Discussion: To our knowledge this is the first described case of GAS purulent pericarditis arising from infective endocarditis. This case contributes to the limited evidence regarding GAS-related purulent pericarditis. Management includes multidisciplinary care with timely administration of broad-spectrum antibiotics, prompt drainage, and contemplation of early surgical intervention. Our review of the 20 reported cases of GAS purulent pericarditis reveals that only 6 out of 20 patients were over 18 years old and the mortality ranged from 40% to 85%. A high degree of clinical suspicion is required as more than half of the cases are diagnosed at post-mortem.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf156"},"PeriodicalIF":0.8,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11983273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patent foramen ovale: life-saving, but breath-taking in fulminant pulmonary embolism. 卵圆孔未闭：挽救生命，但在暴发性肺栓塞中令人叹为观止。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-04-02 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf157

Kathrin Reuthner, Thomas Müller, Alexander Dietl

引用次数: 0

Case report on heart transplantation in endomyocardial fibrosis: 'do not let your guard down'-suspicion of disease recurrence after heart transplantation. 心内膜纤维化心脏移植1例：“不要放松警惕”——怀疑心脏移植后疾病复发。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-04-02 eCollection Date: 2025-05-01 DOI: 10.1093/ehjcr/ytaf149

Lorena Herrador, Jara Gayán-Ordás, Roger Llatjós, Eduard Claver-Garrido, José González-Costello

{"title":"Case report on heart transplantation in endomyocardial fibrosis: 'do not let your guard down'-suspicion of disease recurrence after heart transplantation.","authors":"Lorena Herrador, Jara Gayán-Ordás, Roger Llatjós, Eduard Claver-Garrido, José González-Costello","doi":"10.1093/ehjcr/ytaf149","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf149","url":null,"abstract":"Background: Endomyocardial fibrosis (EMF) is a challenging disease that leads to severe heart failure (HF) due to progressive fibrosis. Diet, parasitic infections, autoimmune disorders, and genetic predisposition have been advocated in EMF pathogenesis, and treatment options for EMF are limited with scarce evidence supporting heart transplantation (HTx).Case summary: A 38-year-old man was diagnosed with EMF with biventricular involvement. The diagnostic work-up ruled out eosinophilia, infections, and autoimmune conditions. The patient rapidly deteriorated, leading to cardiogenic shock with multiorgan failure, and an emergency HTx was performed. Three months later, the graft developed biventricular hypertrophy with atrial fibrosis and the endomyocardial biopsy (EMB) showed extensive inflammation and myocardial damage, compatible with Grade 2R (G3a) cellular rejection. After steroid pulses, the follow-up EMB reveals subendocardial fibrosis and microcalcifications, suggesting the possibility of an EMF recurrence. Nevertheless, the patient had a good clinical outcome, remaining asymptomatic with good graft function 2 years after the transplant.Discussion: This is the first reported case of suspected EMF recurrence following HTx. Given the unknown pathogenesis of EMF, close monitoring is crucial, though HTx appears to be a viable and successful treatment option for these patients.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf149"},"PeriodicalIF":0.8,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond the blueprint: decoding calmodulinopathy-a case report showcasing the utility of multifaceted treatments. 蓝图之外：解码钙调蛋白病——一个案例报告，展示了多方面治疗的效用。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-04-01 DOI: 10.1093/ehjcr/ytaf140

Saikiran Kakarla, Madhusoodanan Jalaja Aswathy, Madhusoodanan Pillai Sreelekshmi, Machilakath Panangandi Shabeer, Narayanan Namboodiri

{"title":"Beyond the blueprint: decoding calmodulinopathy-a case report showcasing the utility of multifaceted treatments.","authors":"Saikiran Kakarla, Madhusoodanan Jalaja Aswathy, Madhusoodanan Pillai Sreelekshmi, Machilakath Panangandi Shabeer, Narayanan Namboodiri","doi":"10.1093/ehjcr/ytaf140","DOIUrl":"10.1093/ehjcr/ytaf140","url":null,"abstract":"Background: Calmodulinopathies are adrenergically-induced life-threatening arrhythmias. Available therapies are disquietingly insufficient, especially for CALM-LQTS (calmodulinopathy-associated long QT syndrome). This case report illustrates a novel mutation in CALM-LQTS and its response to multimodality treatment strategies.Case summary: The proband was the first child born to a nonconsanguineous Indian couple, a 26-year-old woman and a 30-year-old man. The child was delivered prematurely, and at birth, a functional 2:1 atrioventricular block was noted with sinus bradycardia with a corrected QT by Bazzet's of 716 ms. Clinical exome sequencing of the proband revealed a novel missense variant c.287A>G in exon 5 of the CALM3 gene in a heterozygous state, resulting in an Asp96Gly change. The OMIM phenotype associated with it is long QT syndrome 16 (#618782). Despite receiving a dose of 4.5 mg/kg/day of propranolol, the child still had a persistent long QTc. Mexiletine was started at the trial dose of 1.5 mg/kg/day, and after 1 h, QTc was reduced to 507 ms from 560 ms. After a left-cardiac sympathectomy, he remains asymptomatic after 1.3 years of follow-up with a QTc value of 490 ms.Discussion: CALM3 pathogenic variants are gain-of-function variants mainly affecting amino acids residing in the Ca2-binding loops. Earlier data suggested the role of the Nav1.5 channel in leading to persistent Na+ leaks resulting in LQTS. However, they only focused on LQTS-CALM1 and CALM2 models and did not include CALM3-related genes. Despite similarities, the precise impact of CaM on Nav1.5 channels still needs to be defined as CaV1.2. The exact role of mexiletine is not fully understood.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf140"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11969334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143794955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic guided stereotactic radioablation for mid-wall ventricular tachycardia: how to overcome limits of catheter ablation. 磁引导立体定向放射消融治疗中壁室性心动过速：如何克服导管消融的局限性。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-04-01 DOI: 10.1093/ehjcr/ytaf158

Michele Magnocavallo, Pietro Rossi, Domenico Marchesano, Stefano Bianchi

引用次数: 0

Case report demonstrating novel approaches for leadless pacemaker implantation in the single ventricle heart. 病例报告展示了单心室心脏无铅起搏器植入的新方法。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-28 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf146

Patrick Hayle, Fatima Altayeb, Angela Hale, Archana Rao, Reza Ashrafi

{"title":"Case report demonstrating novel approaches for leadless pacemaker implantation in the single ventricle heart.","authors":"Patrick Hayle, Fatima Altayeb, Angela Hale, Archana Rao, Reza Ashrafi","doi":"10.1093/ehjcr/ytaf146","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf146","url":null,"abstract":"Background: The congenital heart disease population can provide a unique set of challenges during pacemaker implant, including the necessity of transvenous leads in a young group of patients. In this case report we demonstrate how leadless pacemakers may be used as an option in patients with Fontan circulation.Case summary: We present two cases of novel use of the Abbott AVEIR™ leadless pacemaker, including the first reported in person trans-baffle delivery of this device and implantation into a single ventricle heart. Our cases are a 30-year-old male with single ventricle physiology and Fontan circulation, found incidentally to have complete heart block (CHB) and a 48-year-old female with a Fontan circulation who had CHB and a history of syncope. These cases demonstrate a variety of venous access routes and add to the existing data of leadless pacemaker implantation in single ventricle physiology. The very long battery life of these devices make them ideal for patients with difficult venous access with bradycardia pacing requirement with low pacing burden.Discussion: Leadless pacemakers offer a valuable alternative to transvenous pacing leads for providing bradycardia pacing support in this patient population.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf146"},"PeriodicalIF":0.8,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aorta-right atrium tunnel and mitral valve prolapse complicated with flail leaflet: a case report of a multimodality approach for an accurate diagnosis. 主动脉-右心房隧道及二尖瓣脱垂合并连枷叶：多模态入路准确诊断1例。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-28 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf147

Andreea Varvara, Ruxandra Oana Jurcuț, Lucian Predescu, Ioana Lupescu, Daniela Oana Andrei

{"title":"Aorta-right atrium tunnel and mitral valve prolapse complicated with flail leaflet: a case report of a multimodality approach for an accurate diagnosis.","authors":"Andreea Varvara, Ruxandra Oana Jurcuț, Lucian Predescu, Ioana Lupescu, Daniela Oana Andrei","doi":"10.1093/ehjcr/ytaf147","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf147","url":null,"abstract":"Background: An aorta-right atrial tunnel (ARAT) is a rare congenital cardiac anomaly that connects the aorta at any coronary sinus to the right atrium. Its cause remains unclear and may involve abnormal origins of the coronary arteries. There is no established link between ARAT and mitral valve prolapse (MVP). Diagnosing ARAT can be challenging, often necessitating multiple imaging techniques, while its management is complex and is further complicated by the association with MVP in our patient.Case summary: We report a case of a 46-year-old man admitted for dyspnoea and palpitations. Thirteen years prior, he had been diagnosed with a cardiac murmur. Echocardiography revealed ARAT and MVP complicated by a flail leaflet and severe regurgitation. AngioCT confirmed the right coronary sinus as the origin of the ARAT and demonstrated the right coronary artery (RCA) arising deep within the tunnel. Cardiac catheterisation identified unclassified pulmonary hypertension due to a left-to-right shunt, along with severe mitral regurgitation. Given the unfavourable anatomy for interventional treatment and the patient's decline in surgery despite multiple consultations, our team opted for conservative management. Currently, the patient's clinical status and echocardiographic parameters remain stable.Discussion: ARAT is a complex congenital disorder that presents diagnostic and treatment challenges, requiring multimodal imaging and teamwork. Since the RCA originates deep within the tunnel and is associated with MVP complicated by flail leaflet and severe regurgitation, we recommend surgical intervention as the appropriate treatment approach. Considering the patient's preferences, conservative treatment was chosen.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf147"},"PeriodicalIF":0.8,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11986323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrapericardial rupture of right atrial angiosarcoma without cardiac tamponade. 无心包填塞的右心房血管肉瘤心包内破裂。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-27 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf154

Tasuku Sato, Shohei Moriyama, Mitsuhiro Fukata, Akira Shiose

引用次数: 0

A calcified, eroded, and thrombosed Mustard: recurrent embolic strokes in a patient with dextro-transpostion of the great arteries corrected by atrial switch-case report. 钙化，侵蚀，血栓形成的芥子气：复发栓塞性中风的病人右转大动脉纠正心房开关病例报告。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-27 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf150

Francisco Javier Ruperti-Repilado, Amadeo Wals-Rodriguez, Miguel Angel Japon, Antonio Gonzalez-Calle, Pastora Gallego

{"title":"A calcified, eroded, and thrombosed Mustard: recurrent embolic strokes in a patient with dextro-transpostion of the great arteries corrected by atrial switch-case report.","authors":"Francisco Javier Ruperti-Repilado, Amadeo Wals-Rodriguez, Miguel Angel Japon, Antonio Gonzalez-Calle, Pastora Gallego","doi":"10.1093/ehjcr/ytaf150","DOIUrl":"10.1093/ehjcr/ytaf150","url":null,"abstract":"Background: After an atrial switch operation, baffle complications such as stenosis and dehiscence are common. While thromboembolic events attributed to baffle leaks are well known, thrombosis at the pulmonary venous baffle as a source of cardioembolic stroke has not been previously reported.Case summary: We describe the case of a 43-year-old Caucasian male with recurrent cardioembolic strokes due to a calcified, broken, and thrombosed baffle with floaty, anticoagulant-resistant thrombi adhered to the side of the pulmonary venous return of Mustard patch. Surgery was the only curative option due to thrombi recurrence under different regimes of anticoagulation.Discussion: A case of recurrent cardioembolic strokes long after Mustard surgery due to thrombi on a heavily calcified pericardial patch is presented. A fracture in the patch led to the exposure of thrombogenic material, which had accumulated around the pacemaker (PM) leads on the systemic venous side of the baffle. This exposure allowed thrombotic material to reach the pulmonary venous side, ultimately entering the subaortic right ventricle and the systemic circulation. In the Mustard procedure, the material used for the baffle construction is prone to degeneration and calcification over time. We hypothesize that chronic mechanical stress from the PM leads might have contributed to the gradual erosion and fracture and consequently thrombosis of the heavily calcified patch, leading to recurrent strokes. Surgery became necessary as aggressive anticoagulation failed to prevent thrombus recurrence.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf150"},"PeriodicalIF":0.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11975534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous atrial fibrillation and sinus rhythm in a heart transplant recipient: ablation guided by novel dispersion analysis: a case report. 同时心房颤动和窦性心律在心脏移植受者：消融指导下的新型离散分析：一个病例报告。

IF 0.8

European Heart Journal: Case Reports Pub Date : 2025-03-26 eCollection Date: 2025-04-01 DOI: 10.1093/ehjcr/ytaf152

Emanuel Heil, Jin-Hong Gerds-Li, Felix Schoenrath, Christoph Knosalla, Felix Hohendanner

{"title":"Simultaneous atrial fibrillation and sinus rhythm in a heart transplant recipient: ablation guided by novel dispersion analysis: a case report.","authors":"Emanuel Heil, Jin-Hong Gerds-Li, Felix Schoenrath, Christoph Knosalla, Felix Hohendanner","doi":"10.1093/ehjcr/ytaf152","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf152","url":null,"abstract":"Background: Atrial fibrillation (AF) in heart transplant recipients poses significant challenges, especially in the context of complex post-surgical cardiac anatomy. This case report describes a rare phenomenon of simultaneous sinus rhythm (SR) and AF in distinct cardiac regions, with AF ablation guided by dispersion analysis using the VOLTA AF Explorer system.Case summary: A 60-year-old male with a history of bicaval orthotopic heart transplantation presented with symptomatic AF. During invasive electrophysiological mapping, AF spontaneously terminated in the donor heart while persisting in the residual atrial tissue of the recipient's heart, specifically the posterior left atrial wall. Dispersion analysis, an experimental AF mapping technique, was employed to identify the arrhythmogenic substrates sustaining AF in the donor and recipient atria. Using this information, targeted and effective radiofrequency ablation was performed on both regions of the left atrium.Discussion: This case highlights the unique challenges of managing AF in heart transplant recipients, particularly when dual rhythms occur in electrically separate regions of the atria. The application of dispersion analysis, though novel and currently supported by limited evidence in this patient population, provided critical insights that enabled precise ablation. The observation of simultaneous SR and AF during invasive mapping underscores the complex post-surgical anatomy characteristic of heart transplant recipients. Dispersion analysis-guided ablation was successfully performed in a patient with electrically distinct donor and recipient atria, each capable of independently sustaining AF. Further studies are warranted to assess the broader utility of this innovative approach in similar clinical scenarios.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf152"},"PeriodicalIF":0.8,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11983099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0