European Heart Journal: Case Reports最新文献_第9页

Case report: rapid progression of conduction system disturbance in unicuspid aortic valve stenosis. 病例报告：单尖瓣主动脉瓣狭窄伴传导系统障碍进展迅速。

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European Heart Journal: Case Reports Pub Date : 2025-08-08 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf394

Aimee McCoubrey, Niki Walker, John Dreisbach, Mark Danton

引用次数: 0

Prosthetic valve dysfunction post-bevacizumab: a transcatheter aortic valve replacement thrombosis case report. 贝伐单抗后瓣膜功能障碍：经导管主动脉瓣置换术血栓病例报告。

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European Heart Journal: Case Reports Pub Date : 2025-08-08 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf370

Denise Mourad, Sachin Singh, Fahd Mohamed, Anwar Zaitoun, Bashar Al Jayyousi

{"title":"Prosthetic valve dysfunction post-bevacizumab: a transcatheter aortic valve replacement thrombosis case report.","authors":"Denise Mourad, Sachin Singh, Fahd Mohamed, Anwar Zaitoun, Bashar Al Jayyousi","doi":"10.1093/ehjcr/ytaf370","DOIUrl":"10.1093/ehjcr/ytaf370","url":null,"abstract":"Background: Transcatheter aortic valve replacement (TAVR) thrombosis is a known complication, but its association with vascular endothelial growth factor (VEGF) inhibitors has not been previously reported.Case summary: A 69-year-old male with previous TAVR developed new-onset prosthetic valve dysfunction after receiving bevacizumab for age-related macular degeneration. Echocardiography revealed moderate aortic stenosis with significantly elevated gradients compared to baseline. Following discontinuation of bevacizumab and initiation of systemic anticoagulation, valve function normalized at three-month follow-up.Discussion: This first reported case of TAVR thrombosis potentially linked to bevacizumab therapy demonstrates a temporal relationship between drug administration and valve dysfunction, with subsequent resolution upon drug discontinuation and anticoagulation. Clinicians should be aware of potential thrombotic complications when prescribing bevacizumab to patients with bioprosthetic valves and maintain regular echocardiographic surveillance. Prompt anticoagulation and medication adjustment may reverse valve dysfunction. Further studies are needed to determine a causal relationship between TAVR thrombosis and VEGF inhibitors.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf370"},"PeriodicalIF":0.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clockwise bundle branch re-entrant ventricular tachycardia in a teenage patient as the first manifestation of dilated cardiomyopathy associated with the p.Ile512Leu TNNI3k variant: a case report. 以p.Ile512Leu TNNI3k变异相关扩张型心肌病为首发表现的青少年患者顺时针束支再入性室性心动过速1例报告

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European Heart Journal: Case Reports Pub Date : 2025-08-08 eCollection Date: 2025-09-01 DOI: 10.1093/ehjcr/ytaf392

Marta González-Quijano, Juan Acosta, Manuel Frutos-López, Eduardo Arana-Rueda, Alonso Pedrote

{"title":"Clockwise bundle branch re-entrant ventricular tachycardia in a teenage patient as the first manifestation of dilated cardiomyopathy associated with the p.Ile512Leu TNNI3k variant: a case report.","authors":"Marta González-Quijano, Juan Acosta, Manuel Frutos-López, Eduardo Arana-Rueda, Alonso Pedrote","doi":"10.1093/ehjcr/ytaf392","DOIUrl":"10.1093/ehjcr/ytaf392","url":null,"abstract":"Background: Bundle branch re-entrant ventricular tachycardia (BBRVT) typically occurs in patients with structural heart disease and conduction abnormalities. Certain genetic mutations may be responsible for conduction disorders leading to BBRVT, especially in young individuals without apparent structural heart disease.Case summary: A 17-year-old male with no pathological history was admitted to our institution due to wide QRS complex tachycardia with right bundle branch block morphology and left superior axis. The patient showed baseline infrahisian conduction abnormalities associated. Although left ventricular (LV) function and diameters were normal at admission, progressive LV dysfunction and dilation were observed during follow-up. Serial cardiac magnetic resonance imaging showed no evidence of myocardial scar. The electrophysiological study confirmed the diagnosis of clockwise BBRVT and a genetic study revealed a missense mutation in TNNI3K (p.Ile512Leu). Due to the high risk of AV block, no ablation was performed, and an implantable cardiac defibrillator was implanted. No recurrences were observed after 3 years of follow-up. Cosegregation analysis revealed cardiac conduction abnormalities and LV dysfunction in variant carriers.Discussion: We report a case of a teenage male with clockwise BBRVT as the initial manifestation of a familial dilated cardiomyopathy associated with the p.Ile512Leu variant in the TNNI3K gene, not previously reported in the literature. This case illustrates the importance of genetic testing in young patients with ventricular arrhythmias and conduction disorders.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 9","pages":"ytaf392"},"PeriodicalIF":0.8,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12404290/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144991784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sinus node dysfunction in a young patient with Hodgkin lymphoma: a case report. 年轻霍奇金淋巴瘤患者窦结功能障碍1例报告。

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European Heart Journal: Case Reports Pub Date : 2025-08-07 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf360

Gabriela-Elena Marascu, Madalina Schmidt, Ruxandra Vidlescu, Mihai Manciu, Eliza Cinteza, Radu-Gabriel Vatasescu

{"title":"Sinus node dysfunction in a young patient with Hodgkin lymphoma: a case report.","authors":"Gabriela-Elena Marascu, Madalina Schmidt, Ruxandra Vidlescu, Mihai Manciu, Eliza Cinteza, Radu-Gabriel Vatasescu","doi":"10.1093/ehjcr/ytaf360","DOIUrl":"10.1093/ehjcr/ytaf360","url":null,"abstract":"Background: Sinus node dysfunction is uncommon among bradyarrhythmias in patients with lymphomas, and it has never been reported in those with Hodgkin lymphoma (HL). We present a case of a young male diagnosed with HL who exhibited asymptomatic sinus node dysfunction.Case summary: A 17-year-old male was diagnosed with stage IV A nodular sclerosis classic type HL. The electrocardiogram showed intermittent sinus arrest with a junctional rhythm. There was no evidence of structural changes in the right atrium (RA) walls during the initial transthoracic echocardiography evaluation. Computed tomography staging revealed multiple mediastinal adenopathies that infiltrated the cardiac level, extending into the RA and interatrial septum. The positron emission tomography scan showed metabolically active adenopathies above the diaphragm and in the upper abdomen, with nuclear uptake primarily in the RA. The patient's conduction and rhythm disorders improved during chemotherapy, highlighting the cardiac involvement linked to the underlying disease.Discussion: To our knowledge, this is the first documented case of HL presenting with sinus node dysfunction as an early sign of cardiac involvement.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf360"},"PeriodicalIF":0.8,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144845010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Music of the heart. 心灵的音乐。

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European Heart Journal: Case Reports Pub Date : 2025-08-07 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf382

Xin Huang, Jialin Liu, William Kongto Hau

引用次数: 0

The iron woman: a case report of contemporary cardiac support. 铁娘子：当代心脏支持1例报告。

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European Heart Journal: Case Reports Pub Date : 2025-08-05 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf371

Jeremy A Brooksbank, Nikolaos Spilias, Carmela D Tan, Randall C Starling, Samir Kapadia

{"title":"The iron woman: a case report of contemporary cardiac support.","authors":"Jeremy A Brooksbank, Nikolaos Spilias, Carmela D Tan, Randall C Starling, Samir Kapadia","doi":"10.1093/ehjcr/ytaf371","DOIUrl":"10.1093/ehjcr/ytaf371","url":null,"abstract":"Background: Modern cardiovascular practice utilizes various devices and procedures to treat functional and structural heart disease.Case summary: We report an interesting case of a female patient with heart failure with reduced ejection fraction (HFrEF) and severe mitral regurgitation who received the full spectrum of available device-based therapies including mitral transcatheter edge-to-edge repair, percutaneous mitral annuloplasty with the Carillon device, temporary mechanical circulatory support, durable left ventricular assist device, and eventually cardiac transplantation.Discussion: Management of HFrEF and functional mitral regurgitation is a common clinical issue for which numerous devices may be utilized to improve patient symptoms and outcomes. In this report, we review indications, supporting data, and anatomical relationships of some of these devices. We also highlight stepwise progression to advanced heart failure requiring temporary and durable mechanical circulatory support followed ultimately by heart transplantation.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf371"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12345415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144845011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photon-counting detector computed tomography for the diagnosis of coronary arteriovenous fistula: a new finding after repair of a coronary fistula case. 光子计数检测器计算机断层扫描诊断冠状动脉动静脉瘘：冠状动脉瘘修复后的新发现。

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European Heart Journal: Case Reports Pub Date : 2025-08-05 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf376

Jiawei Liu, Yonggao Zhang

引用次数: 0

Multi-modality approach to detect device-related thrombus after left atrial appendage occlusion: a case report. 多模态方法检测左心耳闭塞后器械相关血栓1例。

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European Heart Journal: Case Reports Pub Date : 2025-08-05 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf363

Hamady I Maiga, Jana Ambrožič, Borut Jug, Marta Cvijić

{"title":"Multi-modality approach to detect device-related thrombus after left atrial appendage occlusion: a case report.","authors":"Hamady I Maiga, Jana Ambrožič, Borut Jug, Marta Cvijić","doi":"10.1093/ehjcr/ytaf363","DOIUrl":"10.1093/ehjcr/ytaf363","url":null,"abstract":"Background: There has been a growing interest in using left atrial appendage occlusion (LAAO) for stroke prevention in patients with atrial fibrillation (AF) who are ineligible for oral anticoagulation. However, device-related thrombus (DRT) may occur after LAAO implantation and poses significant diagnostic and treatment challenges.Case summary: We describe a case of a patient who suffered an intracranial pontine haemorrhage while on anticoagulation with rivaroxaban for permanent atrial fibrillation and successfully underwent implantation of the LAAO device. Early follow-up transoesophageal echocardiography (TOE) with 3D multi-plane reconstruction revealed a large echo-dense mass on the left atrial aspect of the device. Cardiac computed tomography angiography confirmed a thrombus adherent to the LAAO device. After deciding on the treatment strategy, complete thrombus resolution was achieved at the 6 months follow-up and the patient was free of any thromboembolic and bleeding events.Discussion: Although DRT is a rare complication following LAAO procedure, an accurate diagnosis is crucial for the specific treatment. Multi-modality imaging approach with TOE and cardiac computed tomographic angiography as complementary methods is helpful to detect complications after LAAO procedure in challenging cases.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf363"},"PeriodicalIF":0.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Free floating thrombus in the ascending aorta after extracorporeal cardiopulmonary resuscitation: a case series. 体外心肺复苏后升主动脉游离漂浮血栓：一个病例系列。

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European Heart Journal: Case Reports Pub Date : 2025-08-04 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf375

Marco Tomasino, Maria Vidal-Burdeus, Aitor Uribarri, Francisco González-Santorum, Jordi Riera, María Alejandra Gabaldón, Neiser Palmer, Ignacio Ferreira-González

{"title":"Free floating thrombus in the ascending aorta after extracorporeal cardiopulmonary resuscitation: a case series.","authors":"Marco Tomasino, Maria Vidal-Burdeus, Aitor Uribarri, Francisco González-Santorum, Jordi Riera, María Alejandra Gabaldón, Neiser Palmer, Ignacio Ferreira-González","doi":"10.1093/ehjcr/ytaf375","DOIUrl":"10.1093/ehjcr/ytaf375","url":null,"abstract":"Background: Extracorporeal cardiopulmonary resuscitation (ECPR) using venoarterial extracorporeal membrane oxygenation (V-A ECMO) is an advanced resuscitative measure to improve survival in refractory cardiac arrest. Although ECPR allows for organ perfusion during critical interventions, it carries a high-risk of complications, including thrombosis. Thrombus formation within the ECMO circuit and the patient's vasculature is common, yet focal ascending aortic thrombosis following ECPR is rarely reported.Case summary: We present two case reports of out-of-hospital cardiac arrest managed with ECPR that developed unexpected floating thrombi in the ascending aorta. The first patient, a 45-year-old woman with suspected myocarditis, developed a thrombus that obstructed the left main coronary artery, necessitating surgical thrombus extraction. Despite successful intervention, her cardiac function remained poor, and she required a heart transplant. The second patient, a 46-year-old woman with acute coronary syndrome, had a floating thrombus discovered incidentally. She was managed conservatively but later suffered brain death secondary to cerebral embolism.Discussion: Ascending aortic thrombosis is an underrecognized complication of ECPR, particularly in patients with non-ejecting hearts. Surgical removal of aortic thrombi, as performed in the first case, may prevent embolic events but lacks standardized guidelines. These cases underscore the need for heightened awareness, early detection, and development of management protocols to mitigate thrombotic risks in ECPR patients. Further studies are warranted to establish treatment strategies for this rare but severe complication.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf375"},"PeriodicalIF":0.8,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12352108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A patient with heart failure and coexistence of constrictive pericarditis and Graves' disease: a case report. 心衰合并缩窄性心包炎合并Graves病1例报告。

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European Heart Journal: Case Reports Pub Date : 2025-08-04 eCollection Date: 2025-08-01 DOI: 10.1093/ehjcr/ytaf369

Yuki Nakata, Eiji Shibahashi, Yuji Iwanami, Hajime Kuroda, Hiroyuki Arashi

{"title":"A patient with heart failure and coexistence of constrictive pericarditis and Graves' disease: a case report.","authors":"Yuki Nakata, Eiji Shibahashi, Yuji Iwanami, Hajime Kuroda, Hiroyuki Arashi","doi":"10.1093/ehjcr/ytaf369","DOIUrl":"10.1093/ehjcr/ytaf369","url":null,"abstract":"Background: Thyroid disease is associated with pericarditis. There are several case reports on patients with hyperthyroidism and hypothyroidism complicated by acute pericarditis. However, constrictive pericarditis is a rare complication, particularly in hyperthyroidism, and, to the best of our knowledge, it has not been previously reported.Case summary: A 47-year-old female with no past medical, surgical, or radiotherapy history was admitted to our hospital with a diagnosis of congestive heart failure. Although she was treated for heart failure and hyperthyroidism, the right-sided heart failure did not improve. Right heart catheterization revealed elevated mean right atrial pressure and pulmonary artery wedge pressure. The pressure curve of the right ventricle showed a dip and plateau pattern. The end-diastolic pressure in the left and right ventricles was nearly equal. The cause of heart failure was thought to be constrictive pericarditis, and a pericardiectomy was performed. After surgery, the symptoms and findings of heart failure improved dramatically.Discussion: We encountered a rare case of heart failure complicated by both constrictive pericarditis and Graves' disease. Patients with constrictive pericarditis often lack specific laboratory or imaging findings, which can make diagnosis challenging. When treating patients with treatment-resistant right-sided heart failure, it is important to consider constrictive pericarditis and to evaluate haemodynamic evaluation through catheterization.","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 8","pages":"ytaf369"},"PeriodicalIF":0.8,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0