Miguel Ferrer-Menéndez, Carlos González-Freixa, Meritxell Santaló-Corcoy
{"title":"ECG challenge: identifying a critical pattern in a patient with chest pain and pre-existing right bundle branch block.","authors":"Miguel Ferrer-Menéndez, Carlos González-Freixa, Meritxell Santaló-Corcoy","doi":"10.1093/ehjcr/ytaf192","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf192","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf192"},"PeriodicalIF":0.8,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12022474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ka Ho Oscar Chiu, Lap-Yan Ko, Tai-Leung Daniel Chan, Yuk-Kong Lau, Kwok-Lun Lee
{"title":"Rare case of salmonellosis-related coronary aneurysm, complicated with myocardial infarction and constrictive pericarditis: a case report.","authors":"Ka Ho Oscar Chiu, Lap-Yan Ko, Tai-Leung Daniel Chan, Yuk-Kong Lau, Kwok-Lun Lee","doi":"10.1093/ehjcr/ytaf188","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf188","url":null,"abstract":"<p><strong>Background: </strong>Salmonellosis is a common bacterial disease that usually runs a benign course and most patients recover without specific treatment. However, some develop extra-intestinal complications which can have long-term cardiac implications.</p><p><strong>Case summary: </strong>A 46-year-old man with known ischaemic heart disease presented with fever. The case which was thought to be a viral infection soon developed myocardial infarction, pericardial effusion, and subsequent constrictive pericarditis as a result of salmonellosis. He recovered after targeted antibiotics, repeated pericardial drainage, and surgical interventions.</p><p><strong>Discussion: </strong>This rare case of salmonellosis with infected coronary artery aneurysm and pericarditis emphasizes the importance of history taking, especially food intake in patients with unexplained fever. High index of suspicion is needed and multi-modality serial imaging should be used for early diagnosis and prompt treatment.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf188"},"PeriodicalIF":0.8,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143968446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felipe Israel López-Trejo, Elias Noel Andrade-Cuellar
{"title":"Response to the letter to the editor.","authors":"Felipe Israel López-Trejo, Elias Noel Andrade-Cuellar","doi":"10.1093/ehjcr/ytaf187","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf187","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf187"},"PeriodicalIF":0.8,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12032393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunwen Hu, Guangzhong Liu, Jie Yuan, Da Yin, Yaowang Lin
{"title":"Mutations in the <i>TCAP</i> gene may lead to restrictive phenotype hypertrophic cardiomyopathy with poor prognosis: case report.","authors":"Yunwen Hu, Guangzhong Liu, Jie Yuan, Da Yin, Yaowang Lin","doi":"10.1093/ehjcr/ytaf180","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf180","url":null,"abstract":"<p><strong>Background: </strong>Genetic disorders are a significant cause of cardiomyopathies. Mutations in the <i>TCAP</i> gene (OMIM #604488) encoding the Z-disc protein Telethonin associated with a mixed phenotype of hypertrophic and restrictive cardiomyopathy with poor prognosis have not yet been reported.</p><p><strong>Case summary: </strong>A 47-year-old male presented with heart failure symptoms over a year, which had worsened in the past week. He has a familial history of cardiomyopathy, as his mother was diagnosed with restrictive cardiomyopathy (RCM). Transthoracic echocardiography and cardiac magnetic resonance imaging (CMR) revealed non-obstructive hypertrophic cardiomyopathy (HCM) with severe diastolic dysfunction, biatrial enlargement, preserved ejection fraction, and normal chamber size. Endomyocardial biopsy demonstrated cardiomyocyte hypertrophy and focal fibrosis. The patient was diagnosed with hypertrophic cardiomyopathy with a restrictive phenotype (RP-HCM). Whole exome sequencing identified a frameshift <i>TCAP</i> mutation producing a truncated product (p.Glu12fs) in the family. Despite interventions, the patient's cardiac function progressively deteriorated, leading to his placement on the heart transplant waiting list 1 year later.</p><p><strong>Discussion: </strong>In conclusion, we report for the first time that a heterozygous <i>TCAP</i> frameshift mutation resulting in a truncated protein product may contribute to the development of RP-HCM, providing new insights into the genetic basis of cardiomyopathy with mixed phenotypes.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf180"},"PeriodicalIF":0.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibrahim Antoun, Ayman Helal, Azhar Farooqui, Mohsin Farooq, Mohammad El-Din
{"title":"Right ventricular lead migration to the abdominal cavity: a case report of an unexpected journey.","authors":"Ibrahim Antoun, Ayman Helal, Azhar Farooqui, Mohsin Farooq, Mohammad El-Din","doi":"10.1093/ehjcr/ytaf179","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf179","url":null,"abstract":"<p><strong>Background: </strong>Lead perforation, though an uncommon complication of cardiac device implantation, is associated with significant morbidity, especially when leads migrate to extracardiac structures. Lead migration into the abdominal cavity is exceedingly rare, and management in such cases can be complex.</p><p><strong>Case summary: </strong>We present the case of an 82-year-old woman with known dementia who underwent single-chamber pacemaker implantation for symptomatic Mobitz Type II atrioventricular (AV) block. Two weeks post-implantation, the nursing home staff observed that the patient had bradycardia. Electrocardiogram on hospital admission demonstrated recurrence of Mobitz Type II AV block. Pacing checks confirmed there was no lead sensing. Imaging studies confirmed that the right ventricle lead had perforated the myocardium, passed through the diaphragm, and migrated into the abdominal cavity near the colon. The case was discussed in a multidisciplinary team. The final clinical decision was to extract the displaced lead to avoid the risk of further intra-abdominal organ perforations and the risk of developing pericardial effusion. A new lead was successfully implanted in the septal position, with subsequent follow-up showing stable pacing function. The patient received an extended course of antibiotics and made an uneventful recovery leading up to discharge.</p><p><strong>Discussion: </strong>This case underscores the importance of prompt recognition and a multidisciplinary approach to managing instances of rare lead migration, particularly in elderly, frail patients. Careful imaging and risk assessment helped guide the decision-making process, balancing the risks of lead extraction against potential complications.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf179"},"PeriodicalIF":0.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12032392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143973106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hasan Hadzalic, Selma Hasific, Luca Oechslin, Oliver Gaemperli, Patric Biaggi
{"title":"Prosthetic mitral valve thrombosis associated with new-onset hyperthyroidism due to Graves' disease: a case report.","authors":"Hasan Hadzalic, Selma Hasific, Luca Oechslin, Oliver Gaemperli, Patric Biaggi","doi":"10.1093/ehjcr/ytaf184","DOIUrl":"10.1093/ehjcr/ytaf184","url":null,"abstract":"<p><strong>Background: </strong>Graves' disease is linked to a range of cardiovascular diseases. However, the association of new-onset hyperthyroidism with bioprosthetic valve thrombosis has not been reported yet.</p><p><strong>Case summary: </strong>We present the case of a 59-year-old Caucasian male who developed new-onset overt hyperthyroidism 6 years after undergoing bioprosthetic mitral valve replacement. Echocardiography revealed valve failure with high transmitral gradients caused by valve thrombosis. Following appropriate thyreostatic treatment and anticoagulation, his symptoms resolved, and subsequent evaluations showed resolution of the thrombus and normal valve function.</p><p><strong>Conclusion: </strong>In this case, the association of new-onset hyperthyroidism with bioprosthetic valve thrombosis is highly likely. Hyperthyroidism, characterized by a hypercoagulable state and hypofibrinolytic disorder, is known to be associated with thrombosis and thromboembolic events. As acute hyperthyroidism shows clinical features similar to endocarditis, an interdisciplinary approach, immediate appropriate diagnostic steps and management are crucial for a favourable outcome. This case suggests that hyperthyroidism should be considered in the differential diagnosis when evaluating new-onset valvular thrombosis.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf184"},"PeriodicalIF":0.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144283056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Domingo López Vázquez, Fernando Rueda Núñez, Ramón Calviño Santos, Pablo Piñón Esteban, José Manuel Vázquez Rodríguez
{"title":"Percutaneous management of acute vascular occlusion after transcatheter aortic valve implantation procedure.","authors":"Domingo López Vázquez, Fernando Rueda Núñez, Ramón Calviño Santos, Pablo Piñón Esteban, José Manuel Vázquez Rodríguez","doi":"10.1093/ehjcr/ytaf182","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf182","url":null,"abstract":"","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 5","pages":"ytaf182"},"PeriodicalIF":0.8,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12076143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gen Fujiwara, Yoshiaki Mizutani, Satoshi Yanagisawa, Yasuya Inden, Toyoaki Murohara
{"title":"A novel peak frequency mapping algorithm for the precise localization of accessory pathways in the middle cardiac vein: a case report.","authors":"Gen Fujiwara, Yoshiaki Mizutani, Satoshi Yanagisawa, Yasuya Inden, Toyoaki Murohara","doi":"10.1093/ehjcr/ytaf181","DOIUrl":"https://doi.org/10.1093/ehjcr/ytaf181","url":null,"abstract":"<p><strong>Background: </strong>Advancements in three-dimensional mapping systems have enhanced the precise accessory pathway (AP) localization and conduction properties. However, accurately identifying the earliest atrial or ventricular activation sites remains challenging, particularly in cases with multiple insertions or epicardial connections.</p><p><strong>Case summary: </strong>A 24-year-old woman with palpitations and a manifest Wolff-Parkinson-White syndrome Type A underwent catheter ablation. Local activation time mapping revealed extensive conduction in the posterior mitral annulus, with a peak frequency (PF) of 291 Hz at the earliest ventricular and earliest atrial activation sites on the endocardium in the omnipolar technology near field (OTNF) mapping. The coronary sinus and middle cardiac vein were additionally mapped using an ablation mapping catheter and a 1.6-Fr electrode catheter. Emphasis mapping identified the Kent bundle location during right ventricular pacing using local activation time and PF mapping. A narrower region of atrial insertion at the entrance of the middle cardiac vein was revealed, with a PF of 645 Hz. The AP connection successfully disappeared 8 s after ablation to the entrance of the middle cardiac vein. At the 3-month follow-up, the patient showed no recurrence of delta waves on the electrocardiogram or related symptoms.</p><p><strong>Discussion: </strong>The novel OTNF concept further enhances this function by differentiating far-field potentials based on annotated PFs. The use of PF values with novel OTNF mapping proved valuable in identifying optimal target sites for the ablation of APs. The combination of OTNF mapping and advanced ablation catheters may enable the precise targeting of specific AP sites.</p>","PeriodicalId":11910,"journal":{"name":"European Heart Journal: Case Reports","volume":"9 4","pages":"ytaf181"},"PeriodicalIF":0.8,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}