European Addiction Research最新文献

{"title":"Addiction Psychiatry Training in India: Commentary on Bramness et al., 2022.","authors":"Lekhansh Shukla, Prakrithi Shivaprakash","doi":"10.1159/000537757","DOIUrl":"10.1159/000537757","url":null,"abstract":"","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"156-158"},"PeriodicalIF":2.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140038977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personality Traits and Drug Use: A Longitudinal Study Using Data from the British Cohort Study.","authors":"Eduardo Martínez-Gabaldón, Jorge Eduardo Martínez-Pérez","doi":"10.1159/000541265","DOIUrl":"10.1159/000541265","url":null,"abstract":"<p><strong>Introduction: </strong>Drug use is a significant health, economic and social concern globally. Research indicates that personality traits are crucial in explaining drug use. This paper contributes to the expanding literature by exploring how personality traits at age 10 affect the likelihood of having used any drug at age 30.</p><p><strong>Methods: </strong>Data were extracted from the British Cohort Study 1970. The Big Five dimensions were derived by aggregating items related to distinct traits. Furthermore, probit regression analysis was conducted to ascertain the relationship between personality traits at age 10 and drug use by age 30.</p><p><strong>Results: </strong>Children with low levels of conscientiousness, or agreeableness; or high levels of extraversion, or internal locus of control at the age of 10 are more likely to use any drug in adulthood. In addition, significant differences were observed across gender and types of drugs.</p><p><strong>Conclusions: </strong>These findings suggest that early personality traits play a pivotal role in predicting the likelihood of drug use in adulthood. The results interest policymakers, as they could guide the implementation of personality-targeted interventions to mitigate the adverse effects of specific personality traits. For instance, emotional regulation training could benefit children with low conscientiousness; while stimulating activities such as sports, creative arts, or music could engage children with high extraversion.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"357-365"},"PeriodicalIF":2.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142461006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effectiveness of a Quitline for Smoking Cessation: Results of a Randomized Controlled Trial.","authors":"Simone Delle, Ludwig Kraus, Simona Maspero, Oliver Pogarell, Eva Hoch, Kirsten Lochbühler","doi":"10.1159/000541682","DOIUrl":"10.1159/000541682","url":null,"abstract":"<p><strong>Introduction: </strong>Smoking remains a significant global public health issue, leading to numerous preventable deaths and disabilities annually. Telephone counselling is a recommended intervention for smoking cessation, offering accessible support to a wide range of people who smoke. This study aimed to evaluate the long-term effectiveness of the German quitline for smoking cessation.</p><p><strong>Methods: </strong>A parallel-group, two-arm, superiority, randomized controlled trial was conducted between October 2021 and November 2023. People who smoked daily and were willing to quit received either up to six telephone counselling calls (intervention group) or a self-help brochure (control group). Seven-day point prevalence abstinence from cigarettes and tobacco at 12 months and prolonged cigarette and tobacco abstinence from 3 to 12 months after the start of the intervention were assessed. Further, the use of additional cessation aids was assessed.</p><p><strong>Results: </strong>A total of n = 905 participants were randomized (intention-to-treat sample). The intervention group (n = 477) exhibited higher rates of prolonged cigarette abstinence (31.7% vs. 17.8%) and prolonged tobacco abstinence (30.8% vs. 15.2%) compared to the control group (n = 428) at 12-month follow-up with corresponding odds ratios of 2.2 (95% CI [1.6, 3.0]) and 2.5 (95% CI [1.8, 3.5]). Seven-day point-prevalence cigarette abstinence was not statistically significant (OR = 1.3, 95% CI [1.0, 1.7]). E-cigarettes were the most commonly used additional cessation aid (46.0%), followed by electronic media (31.0%) and nicotine replacement therapy (26.2%).</p><p><strong>Conclusions: </strong>Telephone counselling provided by the national German quitline for smoking cessation demonstrates effectiveness in promoting long-term abstinence from cigarettes and tobacco. Increased awareness and use of the quitline could promote cessation rates in Germany. Given the rising popularity of novel nicotine consumer products, counselling protocols should incorporate information on their risks and potential as cessation tools.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"366-377"},"PeriodicalIF":2.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142497431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contents Vol. 29, 2023","authors":"K. Ersche, Robert Whelan, Peter Blanken, Jørgen G. Bramness – Norwegian","doi":"10.1159/issn.1022-6877","DOIUrl":"https://doi.org/10.1159/issn.1022-6877","url":null,"abstract":"","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"83 10","pages":"I - VI"},"PeriodicalIF":3.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139026000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front & Back Matter","authors":"","doi":"10.1159/000533225","DOIUrl":"https://doi.org/10.1159/000533225","url":null,"abstract":"","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46711761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern and Socio-demographic characteristics of Drug Users at the National Drug Law Enforcement Agency (NDLEA) Rehabilitation Facility, Port Harcourt","authors":"Nkporbu Ak, Stanley Pc","doi":"10.33425/2639-8451.1035","DOIUrl":"https://doi.org/10.33425/2639-8451.1035","url":null,"abstract":"Background: Substance abuse particularly among young people has become a large phenomenon globally affecting all segments of society. The abuse of alcohol, tobacco, cannabis and other psychoactive drugs among young people has become an issue of public health concern with untold negative consequences on human existence. Aim: This study sought to examine the sociodemographic profiles and patterns of drug use among drug users at the NDLEA Rehabilitation Facility, Port Harcourt. Materials and Methods: This was a descriptive cross-sectional study conducted among inmates of the National Drug Law Enforcement Agency (NDLEA), Port Harcourt. A structured questionnaire covering socio-demographic characteristics and other factors were self-administered to inmates of the facility, who have been brought by their relative for addiction care over a period of 3 years (2017 to 2020). Ethical approval was obtained from the ethical committee of the University of Port Harcourt Teaching Hospital and approval was obtained from the NDLEA Authority. All other ethical provisions were followed. Descriptive statistics was used to analyzed the data. Data were analyzed with number count, percentage, and then Chi-square of independence. Results: Majority of the drug users were male (98,8%), single (72.5%), unemployed (27.5%) and apprentice (40.0%), between the ages of 15 and 35 (67.5%) and with tertiary education. Cannabis was the most consumed drug (75.7%), followed by nicotine (30.8%) alcohol (28.3%), cocaine (27.4%) and heroine (25.8%). Majority of the users were introduced to drug by friends and family members and referred to the feeling they got on the first day of use as high and happy. Majority had 15 to 25 years as age of onset of drug use and there were no family history of psychoactive substance use or mental illness. Conclusion: Substance use is common among young people between the ages of 26 and 30, single, with higher level of education and low-income earners. Majority use illicit drugs, which they started at early age of 15 to 25 and introduced to by friends and family members. Improvement in socio-economic status of adolescents and sustained public health enlightenment will help to reduce the rising prevalence of drug use.","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"7 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81235767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pattern and Prevalence of Drug Use among a Population of Mentally Ill Patients attending the University of Port Harcourt Teaching Hospital","authors":"Nkporbu Ak, Ojule In","doi":"10.33425/2639-8451.1034","DOIUrl":"https://doi.org/10.33425/2639-8451.1034","url":null,"abstract":"Background: People with mental illness are at increased risk for substance use and individuals who experience a substance use disorder (SUD) during their lives may experience a co-occurring mental disorder and vice versa. The dual diagnosis often affects the illness course, worsens prognosis and presents a management difficulty. Aim: This study aimed to look at the prevalence of psychoactive use among mentally ill patients at the University of Port Harcourt Teaching Hospital. Materials and Methods: This was a descriptive cross-sectional study conducted among attendees of Neuropsychiatric Outpatient Clinic of the University of Port Harcourt Teaching Hospital (UPTH). A structured questionnaire covering socio-demographic characteristics and other factors were self-administered to 75 patients diagnosed with various psychiatric disorders by consultants Psychiatrists and attending the out-patient clinic via a systematic random sampling. Ethical approval was obtained from the ethical committee of the University of Port Harcourt Teaching Hospital and all other ethical provisions were followed. Descriptive statistics was used to analyze the data. Results: Majority of the respondents were male (81%), single (76.0%), unemployed (36.0%), low income earners (73.4%) and between the ages of 21 and 30 (44%).. Majority had tertiary education (58.7%) followed by respondents with secondary education (33.3%). The prevalence of psychoactive substance use was 48% with Cannabis being the most reported consumed drug (24%), cocaine 16%, nicotine 14.7%, heroine 10.7%, alcohol 6.7%, then volatile substance and hypno-sedation 2.7% and 1.3% respectively. Majority of the Respondents had use drugs between 1- 10 years. Conclusion: Drug use is common among the persons suffering from mental disorders in UPTH. Better evaluation for and proper management of this dual diagnosis will help to improve their mental well-being and quality of life.","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"83 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79987751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Traumatic Events on Substance Use among Internally Displaced People in Selected Flood and War Impacted Areas in Rivers State","authors":"Nkporbu Ak, Oti Ik, Stanley Pc","doi":"10.33425/2639-8451.1033","DOIUrl":"https://doi.org/10.33425/2639-8451.1033","url":null,"abstract":"Background: Different individuals react differently to emotionally traumatic events just as there are varying degrees of coping mechanisms. One of the common maladaptive coping mechanisms of victims of internal displacement is increased predisposition to substance use. Aim: This study determined the relationship between stressful life events and substance use among victims of flood and wars in selected parts of Rivers State. Methods: A cross-sectional study was conducted in 4 different flood and war impacted areas where 357 respondents were investigated. Ethical procedures were followed including consent from participants. Respondents of between the ages 10-75 years were included in the study and their socio-demographic characteristics determined. The Impact of Event Scale –Revised (IES-R) was used to assess posttraumatic symptomatology of the flood victims, while the CAGE and a semi-structured questionnaire were used to assess alcohol and other psychoactive substances. Rapid urine drug toxicology was done for the respondents. Data was analysed using the SPSS version 20. p≤0.05 was considered statistically significant. Results: Two hundred and eighty (79.6%) respondents had IES-R score of 22 and above while 65.3% (n=233) scored 33 and above. Prevalence of substance use was 34.4% (n=123) from self-report and 41.7% (n=149) from urine toxicology. Of the 149 respondents, 138 was among those who scored IES-R 22 and above while 11 was among those who scored below 22 (p=0.001). Alcohol was the most consumed drug with 22.65 (n=81), followed by cannabis with 18.8% (n=67), tramadol 16.5% (n=59), codeine 15.7% (n=56), Nicotine 14.8% (n=53), kolanut and khatchewing 6.4% (n=23), and benzodiazepam 12.8% (n=64). Polysubstance use was 34.17% (n=122). Three respondents use drug intravenously. Substance use significantly correlated with IES-R scores (p=0.002). Conclusion: Stressful and traumatic events may increase vulnerability to substance use, therefore Internally Displaced People (IDP) may require substance use disorder services and psychological care.","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"54 1","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87623189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Metabotropic Glutamate Receptor Subtype 5 in Mouse Models of Cocaine Addiction","authors":"Marion Nicole, Briggs Lily, Donar Andrew, Godin Brandon, LaCrosse Amber","doi":"10.33425/2639-8451.1036","DOIUrl":"https://doi.org/10.33425/2639-8451.1036","url":null,"abstract":"Cocaine is a psychostimulant that is one of the most widely used illicit drugs, particularly in America. Cocaine addiction is a chronic relapsing disease that is characterized by drug craving and loss of inhibitory control. Animal models of psychiatric diseases are essential to identify underlying neural circuitry and to test the effectiveness of novel pharmacotherapies to prevent relapse. Current research using animal models indicates that type 5 metabotropic glutamate receptors may be of particular importance to the onset and maintenance of cocaine addiction. This literature review provides a general overview of the glutamate system, and the animal models frequently used in the study of addiction and summarizes peer-reviewed research focused on cocaine-induced adaptations to the type 5 metabotropic glutamate receptors in mice. Cocaine administration in mouse models induces a range of neural changes in the brain, reflecting the neuroadaptations associated with cocaine addiction. Cocaine-induced adaptations to type 5 metabotropic glutamate receptor vary by brain region and by methodological constraints. Key neural changes that occur in the mouse brain following cocaine administration include adaptations in the dopaminergic and glutamatergic systems. The interplay between mGluR5 and the dopamine system plays a significant role in the neurobiological adaptations that drive cocaine addiction. Lastly, we cover the potential efficacy of targeting this receptor as a novel therapeutic option to prevent cocaine relapse. Selective antagonists of this receptor have been studied for their potential therapeutic effects in mouse models of cocaine addiction. These compounds reduce the conditioned responses to drug-associated cues and reduce the motivation to seek cocaine, thereby inhibiting relapse-like behavior, and have been found to modulate synaptic plasticity in brain regions involved in addiction, such as the nucleus accumbens and prefrontal cortex. Overall, these compounds demonstrate promising effects in mouse models of cocaine addiction.","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136300590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front & Back Matter","authors":"","doi":"10.1159/000531384","DOIUrl":"https://doi.org/10.1159/000531384","url":null,"abstract":"","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42715543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}