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The Association of Substance Use and Antisocial Behaviours with the Probability of Gambling among Adolescents. 青少年中物质使用和反社会行为与赌博概率的关系。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-05-24 DOI: 10.1159/000546587
Emina Mehanović, Mariaelisa Renna, Erica Viola, Giulia Giraudi, Maria Ginechesi, Claudia Vullo, Alberto Sciutto, Marco Martorana, Adalgisa Ceccano, Pietro Casella, Fabrizio Faggiano, Federica Vigna-Taglianti
{"title":"The Association of Substance Use and Antisocial Behaviours with the Probability of Gambling among Adolescents.","authors":"Emina Mehanović, Mariaelisa Renna, Erica Viola, Giulia Giraudi, Maria Ginechesi, Claudia Vullo, Alberto Sciutto, Marco Martorana, Adalgisa Ceccano, Pietro Casella, Fabrizio Faggiano, Federica Vigna-Taglianti","doi":"10.1159/000546587","DOIUrl":"10.1159/000546587","url":null,"abstract":"<p><strong>Introduction: </strong>Gambling behaviour among adolescents is a serious public health concern. Adolescents' involvement in gambling is often related with substance use and antisocial behaviours. This study aims to examine the association of substance use and antisocial behaviours with gambling among Italian early adolescents.</p><p><strong>Methods: </strong>The analytical sample of the present study included 1,822 students attending 29 secondary schools in nine NHS districts of Piedmont region and the city of Rome who participated in the baseline survey of the experimental controlled trial \"GAPUnplugged.\" The association of lifetime cigarette smoking, alcohol drinking, drunkenness, illicit drug use, violence, and stealing with the probability of any gambling and regular gambling was estimated through multilevel mixed-effect regression models.</p><p><strong>Results: </strong>The prevalence of any gambling and regular gambling in the last 30 days was 36.4% and 12.7%, respectively. After adjustment for potential confounders, cigarette smoking, alcohol drinking, drunkenness, violence, and stealing were significantly associated with an increased probability of both gambling outcomes. The link of gambling outcomes with alcohol drinking and drunkenness was higher for females, whereas the association with violence and stealing was higher for males.</p><p><strong>Conclusion: </strong>Due to the association of gambling with other problem behaviours during early adolescence, school-based health promotion and prevention interventions should address multiple risk behaviours simultaneously. Prevention of one risk behaviour may contribute to the prevention of other risk behaviours.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"147-156"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Systematic Investigation of the Common Genetic Architecture of Substance Use Traits and the Relationship with Mental Health. 物质使用特征的共同遗传结构及其与心理健康的关系的系统调查。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-05-30 DOI: 10.1159/000546680
Joëlle A Pasman, Andrea G Allegrini, Adria Tunez, Abdel Abdellaoui, Dirk J A Smit, Michel G Nivard, Jacqueline M Vink, Karin J H Verweij
{"title":"A Systematic Investigation of the Common Genetic Architecture of Substance Use Traits and the Relationship with Mental Health.","authors":"Joëlle A Pasman, Andrea G Allegrini, Adria Tunez, Abdel Abdellaoui, Dirk J A Smit, Michel G Nivard, Jacqueline M Vink, Karin J H Verweij","doi":"10.1159/000546680","DOIUrl":"10.1159/000546680","url":null,"abstract":"<p><strong>Introduction: </strong>Understanding shared and unique genetic vulnerability for substance use traits will give insight into the etiology of their comorbidity with psychiatric and other health outcomes.</p><p><strong>Methods: </strong>We applied genomic structural equation modeling to summary statistics from genome-wide association studies (GWASs) to map the genetic architecture of fourteen substance use traits across five substances (tobacco, alcohol, cannabis, cocaine, and opioids) and three stages (initiation, frequency, and dependence). We systematically compared data-driven and theory-based models and conducted sensitivity analyses. We estimated the genetic correlations between the latent factors and psychiatric, physical, socioeconomic, cognitive, and social traits.</p><p><strong>Results: </strong>A wide range of models could be fit to the data. A data-driven 4-factor model was the most parsimonious, although bifactor models per substance or per stage also fit well. The four factors from the data-driven model were named smoking/other, dependence, alcohol, and cannabis. F1-smoking/other was most strongly related to socioeconomic traits (negatively), whereas F2-dependence and F4-cannabis were mostly related to externalizing and risk behavior (positively). F3-alcohol showed weaker overlap with unfavorable outcomes.</p><p><strong>Conclusions: </strong>Genetic risk for substance use traits is partly overlapping, both per substance and per stage of use. Contrasting such categories' liability profiles provides insight into differences in their etiology and associations with poor outcomes.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"179-196"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ESCAPE Study: Cannabidiol Use in Patients Treated for Substance Use Disorders, Prevalence of Use, and Characteristics of Users. ESCAPE研究:大麻二酚在治疗物质使用障碍患者中的使用,使用的流行程度和使用者的特征。
IF 2.8 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2024-12-02 DOI: 10.1159/000541887
Mélanie Duval, Marion Istvan, Morgane Rousselet, Edouard-Jules Laforgue, Marie Grall-Bronnec, Claire Mauriat, Caroline Victorri-Vigneau
{"title":"ESCAPE Study: Cannabidiol Use in Patients Treated for Substance Use Disorders, Prevalence of Use, and Characteristics of Users.","authors":"Mélanie Duval, Marion Istvan, Morgane Rousselet, Edouard-Jules Laforgue, Marie Grall-Bronnec, Claire Mauriat, Caroline Victorri-Vigneau","doi":"10.1159/000541887","DOIUrl":"10.1159/000541887","url":null,"abstract":"<p><strong>Introduction: </strong>Cannabidiol (CBD) is one of the two primary phytocannabinoids found in cannabis. Its diverse pharmacological properties suggest potential benefits for a wide range of medical conditions. The primary objective of this study was to estimate the prevalence of CBD use among patients being treated for substance use disorder. Additionally, we aimed to characterize the pattern of CBD use and describe the profiles of users.</p><p><strong>Methods: </strong>Patients admitted to two substance use disorder departments between May 6, 2020, and July 23, 2021, were included in the study. Sociodemographic, medical and substance use data, including CBD use, were collected. A multiple correspondence analysis (MCA) was performed to identify substance uses most frequently correlated with CBD use. Multivariate analyses were also conducted to identify factors associated with CBD use.</p><p><strong>Results: </strong>The prevalence of CBD use in the past 12 months among the 183 patients was 38.2%. However, at the time of the study, 63% had stopped using CBD, primarily due to its perceived ineffectiveness and cost. CBD was commonly consumed via inhalation, either by smoking the plant or using e-cigarette liquids. The MCA revealed that while there is no typical profile of CBD users, they were more likely to use sedative substances rather than stimulants. CBD users were younger and more likely to have psychiatric comorbidities.</p><p><strong>Conclusion: </strong>The prevalence of CBD use was notably high. Given the significant risk of drug interactions with CBD and its wide variability in composition, it is crucial for clinicians to routinely inquire about CBD use. The potential for self-therapeutic or recreational use in these patients appears to be underestimated.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"35-46"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in Self-Reported Mental Health, Anxiety, and Depression among Patients in Heroin-Assisted Treatment: Findings from a Norwegian Trial Project. 在海洛因辅助治疗中患者自我报告的心理健康、焦虑和抑郁的变化:来自挪威试验项目的发现。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-07-22 DOI: 10.1159/000547375
Lars Henrik Ryther Myklebust, Desiree Eide, Linda Elise C Wüsthoff, Francesca Melis, Ann L Oldervoll, Silvana De Pirro, Thomas Clausen
{"title":"Changes in Self-Reported Mental Health, Anxiety, and Depression among Patients in Heroin-Assisted Treatment: Findings from a Norwegian Trial Project.","authors":"Lars Henrik Ryther Myklebust, Desiree Eide, Linda Elise C Wüsthoff, Francesca Melis, Ann L Oldervoll, Silvana De Pirro, Thomas Clausen","doi":"10.1159/000547375","DOIUrl":"10.1159/000547375","url":null,"abstract":"<p><strong>Introduction: </strong>Norway's heroin-assisted treatment (HAT) project started in 2022, aimed at targeting individuals with severe opioid use disorder (OUD) who did not benefit from first-line, conventional opioid agonist treatment. The use of pharmaceutical diacetylmorphine in HAT may particularly benefit patients with comorbid psychiatric disorders due to its structured nature, which includes daily contact with outpatient clinics. However, previous findings on mental health outcomes in HAT have been inconclusive. The main aim of this study was to explore changes in patients' self-rated mental health and anxiety and depression over the first 12 months of HAT in Norway.</p><p><strong>Methods: </strong>We used data from 2 questions about patients' self-rated mental health and anxiety and depression collected from 79 patients at the start of treatment (baseline) and at 3, 6, and 12 months into treatment. Ordinal logistic regression models were used to examine the changes in the responses over the observational period and to explore the potential effects of predictors such as gender and age, self-reported substance use, and clinic site.</p><p><strong>Results: </strong>We found a gradual improvement in self-rated mental health from baseline over the observational period, with a statistically significant shift in response distribution at the 12-month mark (p = 0.017). The distribution of responses indicating \"good\" mental health increased with a 35% improvement at 12 months, with a corresponding decline of 48% in \"bad\" mental health. For self-rated anxiety and depression, we found no change in severity of self-rated symptoms. A decline of 48% in the proportion of responses reporting severe symptoms at 12 months was aligned with a simultaneous increase of 17% reporting moderate symptoms. Age and previous suicide attempts were significant predictors of both outcomes; gender influenced anxiety and depression only, whereas clinic site influenced only mental health ratings.</p><p><strong>Conclusion: </strong>HAT appears to gradually improve patients' self-rated mental health over time, possibly by enhancing overall psychological well-being. Self-rated symptoms of anxiety and depression may not be affected by this treatment, indicating that psychiatric conditions can persist in HAT for those struggling with them. This highlights the importance of specific psychiatric assessments and targeted interventions for at least a subset of patients, underscoring the need for integrated treatment approaches within HAT programs that address both substance use and co-occurring psychiatric disorders.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"286-296"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individual and Contextual Determinants of Substance Use among Refugees in Shared Accommodations: A Cross-Sectional Multilevel Analysis. 在共享住宿的难民中物质使用的个人和环境决定因素:横断面多层次分析。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-10-02 DOI: 10.1159/000548714
Jonathan Uricher
{"title":"Individual and Contextual Determinants of Substance Use among Refugees in Shared Accommodations: A Cross-Sectional Multilevel Analysis.","authors":"Jonathan Uricher","doi":"10.1159/000548714","DOIUrl":"10.1159/000548714","url":null,"abstract":"<p><strong>Introduction: </strong>The increasing number of refugees in the European Union has led to challenges in terms of allocation and housing. Shared accommodation, which often presents vulnerable living conditions, may exacerbate health risks including substance use (SU). This study aimed to identify individual and contextual determinants of substance use behaviours (SUBs) among refugees in shared accommodations.</p><p><strong>Methods: </strong>Data from a cross-sectional study and baseline data from an evaluation study resulted in a sample size of 391 refugees residing in 22 shared accommodations in Stuttgart, Germany. Data were collected using self-reported measures of SU as well as physical and mental health indicators at the individual level and conditions of shared accommodations on a contextual level. Multilevel logistic regression analysis was performed to examine individual-level and contextual factors.</p><p><strong>Results: </strong>SUBs were influenced primarily by individual factors. Male refugees were more likely to engage in SU than females, whereas being Muslim was associated with a lower likelihood of SU. Prolonged residence in shared accommodations and possession of a work permit increase the risk of SU. Poor physical health was also correlated with higher SUBs. Contextual factors, such as deteriorating conditions or isolation due to limited access to support systems, played a smaller role. However, deteriorated accommodation conditions were unexpectedly linked to a reduced likelihood of hazardous SU.</p><p><strong>Conclusion: </strong>The findings highlight the predominance of individual-level determinants over contextual factors in shaping SUBs among refugees in shared accommodations. Interventions should prioritize addressing individual vulnerabilities, such as health and social integration challenges, while improving living conditions to mitigate risks. These insights can inform targeted European policies and support programmes for refugee populations.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"384-395"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum. 勘误表。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-12-04 DOI: 10.1159/000549004
{"title":"Erratum.","authors":"","doi":"10.1159/000549004","DOIUrl":"10.1159/000549004","url":null,"abstract":"<p><p>In the article by Bretteville-Jensen and Nesse entitled \"Non-Prescribed Use of Opioid Agonist Medications and Associations with Non-Fatal Overdoses: A Repeated Cross-Sectional Study across a Decade of Reduced Monitoring\" [Eur Addict Res. 2025; https://doi.org/10.1159/000547909], an error was introduced during production concerning the license. The article was mistakenly published under a CCC license instead of the intended CC BY 4.0 license.The original article has been updated.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"409"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12890261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Examination of Cryptocurrency Trading Behaviors in Relation to Gambling Disorder and Psychological Risk Factors. 加密货币交易行为与赌博障碍和心理风险因素的关系研究。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-08-25 DOI: 10.1159/000548027
Adalet Yardımcı, Başak Ünübol
{"title":"The Examination of Cryptocurrency Trading Behaviors in Relation to Gambling Disorder and Psychological Risk Factors.","authors":"Adalet Yardımcı, Başak Ünübol","doi":"10.1159/000548027","DOIUrl":"10.1159/000548027","url":null,"abstract":"<p><strong>Introduction: </strong>Cryptocurrencies are digital assets that differ from traditional currencies in their unique characteristics. An increasing number of individuals are showing interest in cryptocurrency trading and spending long hours engaged in this activity. Current studies point out that some behaviors of cryptocurrency investors may be associated with problematic mental health outcomes. The present study aims to investigate problematic cryptocurrency trading behaviors and to examine these behaviors in terms of gambling disorder and psychological risk factors.</p><p><strong>Methods: </strong>Two hundred four volunteered participants whose ages ranged between 18 and 65 years (mean = 31.62, SD = 6.95) were recruited. For data collection, the Problematic Cryptocurrency Trading Scale, Problem Gambling Severity Index, Eysenck Personality Questionnaire Revised - Abbreviated Form, UPPS Impulsive Behavior Scale, and Positive and Negative Affect Schedule were administered.</p><p><strong>Results: </strong>Findings demonstrated that participants exhibiting symptoms of problematic cryptocurrency trading had higher levels of problem gambling severity, negative emotions, extraversion, and urgency, along with lower levels of premeditation and perseverance. Additionally, the linear regression with backward elimination revealed that problem gambling severity and extraversion are associated with problematic cryptocurrency trading.</p><p><strong>Conclusion: </strong>These findings suggest that greater engagement in cryptocurrency speculation may be associated with increased gambling behaviors and that both activities could be linked to underlying personality traits, impulsivity, and negative emotions.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"297-307"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacokinetics-Driven Individualized Detoxification Procedure in Patients Dependent on Benzodiazepines and Other GABA-A Receptor Modulators. 依赖苯二氮卓类药物和其他GABA-A受体调节剂的患者的药代动力学驱动的个体化解毒程序。
IF 2.3 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-07-05 DOI: 10.1159/000547221
Anna R Basińska-Szafrańska
{"title":"Pharmacokinetics-Driven Individualized Detoxification Procedure in Patients Dependent on Benzodiazepines and Other GABA-A Receptor Modulators.","authors":"Anna R Basińska-Szafrańska","doi":"10.1159/000547221","DOIUrl":"10.1159/000547221","url":null,"abstract":"<p><strong>Introduction: </strong>Despite extreme inter-patient differences in the benzodiazepine (BZD) metabolism rate, patients dependent on BZDs or other GABA-A receptor modulators are treated without laboratory control. The proposed detoxification method is the first to employ concentration feedback to prevent routinely unrecognized problems: overaccumulation of a long-acting BZD substitute, high concentration upon discontinuation (mimicking patients' adaptation to \"abstinence\"), elimination continuing long after treatment conclusion, resulting in delayed low-concentration crises and relapses of drug intake.</p><p><strong>Methods: </strong>A new method, although evolved from a typical gradual dose reduction approach, is driven not by a dosage schedule but by an individual BZD concentration evolution. This defines four treatment stages: Substitution, anti-accumulation paradigm, elimination, and readaptation (SAER). The S stage, substitution by titration (using diazepam or clorazepate, well read by immunoassays) ends with achieving a satiation state and establishing individual clinical state and concentration baselines. During the A stage, to minimize further (unneeded) accumulation, doses are aggressively reduced daily, driven by concentration feedback, until accumulation ceases (a quasi-plateau). Further tapering opens the E stage (actual detoxification), hence slows, depending on the patient's condition and elimination rate, and concentration is tracked with lower frequency (every 3-7 days), including after drug discontinuation. Only after complete elimination (R stage), patients adapt to true abstinence.</p><p><strong>Conclusions: </strong>The SAER approach can minimize overaccumulation-related errors. The use of serum-BZD feedback curbs the initial overaccumulation. A forced concentration plateau establishes optimized initial conditions for the elimination process. By minimizing a superfluous high-concentration treatment phase, SAER provides more time for careful escorting of the low-concentration crises, especially the one coinciding with elimination completion, weeks after drug discontinuation. Without extending the usual treatment time, the method aspires to improve both the reliability of the detoxification process and the treatment completion rate.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"264-273"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diversion of Diacetylmorphine in Heroin-Assisted Treatment: A Focus Group Study among Patients and Treatment Providers. 二乙酰吗啡在海洛因辅助治疗中的转移——一项针对患者和治疗提供者的焦点小组研究。
IF 2.8 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-03-13 DOI: 10.1159/000545162
Elisabeth Strickler, Zacharias Wicki, Jean N Westenberg, Johannes Strasser, Undine E Lang, Kenneth M Dürsteler, Maximilian Meyer, Marc Vogel
{"title":"Diversion of Diacetylmorphine in Heroin-Assisted Treatment: A Focus Group Study among Patients and Treatment Providers.","authors":"Elisabeth Strickler, Zacharias Wicki, Jean N Westenberg, Johannes Strasser, Undine E Lang, Kenneth M Dürsteler, Maximilian Meyer, Marc Vogel","doi":"10.1159/000545162","DOIUrl":"10.1159/000545162","url":null,"abstract":"<p><strong>Introduction: </strong>Heroin-assisted treatment (HAT) involves the supervised administration of pharmaceutical heroin (diacetylmorphine; DAM), either injectable or oral, for individuals with severe opioid use disorder who have not achieved stabilisation with conventional opioid agonist treatment. Despite its growing adoption, there is limited literature on the phenomenon of diversion in HAT. Diversion refers to the redirecting of legal prescription medications from their intended medical use to illegal or unauthorised use. This study aimed to investigate the reasons for, experiences with, and consequences of DAM diversion, as reported by both patients and treatment providers.</p><p><strong>Methods: </strong>In this qualitative study, two separate focus groups were conducted with patients and treatment providers (nurses, psychiatrists, social workers, and psychologists), respectively. Discussions were audio-recorded, transcribed, and analysed. Mayring's qualitative content analysis was used to evaluate the findings.</p><p><strong>Results: </strong>Five themes with fourteen categories emerged. Providers and patients both described procedures and motives of diversion, discussed the positive and negative consequences, and suggested solutions for reduced future diversion of DAM. An important motif for diversion stemmed from patients' urge for more autonomy over route, timing, and fractioning of administration, while also being used to finance concurrent cocaine use. Treatment providers and patients both noted that diversion may lead to increased overdose risk for individuals in and out of treatment. Nurses noted a substantial negative impact of diversion on the therapeutic relationship. Suggestions for reducing diversion included allowing for more take-home dosing, allowing for more flexibility in routes of administration, adapting HAT clinic opening hours, and providing effective treatment for cocaine use disorder.</p><p><strong>Conclusion: </strong>The main drivers of diversion in HAT included a desire for more autonomy, unaddressed concurrent substance use, and significant barriers to the existing treatment options. Addressing patients' preferred opioid effect profile, accommodating their social needs, and managing concurrent cocaine use disorders may reduce diversion in the future.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"87-98"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Associations between Cannabis Prices, Stores, and Usage after Recreational Legalization. 探索大麻价格、商店和娱乐性合法化后使用之间的联系。
IF 2.8 3区 医学
European Addiction Research Pub Date : 2025-01-01 Epub Date: 2025-03-07 DOI: 10.1159/000544104
Michael J Armstrong
{"title":"Exploring Associations between Cannabis Prices, Stores, and Usage after Recreational Legalization.","authors":"Michael J Armstrong","doi":"10.1159/000544104","DOIUrl":"10.1159/000544104","url":null,"abstract":"<p><strong>Introduction: </strong>Canada legalized recreational cannabis in October 2018, but commercial retailing took time to develop. This study first explored how self-reported cannabis use prevalence, daily use, product type use, and age of initial use changed during 2019-2023. It then analyzed whether the changes were associated with rising store numbers or falling prices.</p><p><strong>Methods: </strong>Data on store counts, retail pricing, and cannabis use came from government reports covering 10 provinces over 5 years. Panel data linear regressions analyzed 50 province-year aggregated observations.</p><p><strong>Results: </strong>There were no significant changes in prevalence among males and people aged 16-24 or in the proportion using cannabis daily. Prevalence among females and people aged 25+ increased; those levels showed negative associations with prices but not stores. Dried cannabis use decreased, while edibles use increased; those also showed associations with prices but not stores. Mean initial age of use increased; it was negatively associated with prices and positively with stores.</p><p><strong>Conclusion: </strong>Canada's large cannabis retail expansion was accompanied by relatively modest usage changes, most of which showed associations with falling prices but not rising store counts.</p>","PeriodicalId":11902,"journal":{"name":"European Addiction Research","volume":" ","pages":"125-132"},"PeriodicalIF":2.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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