The Pediatric Infectious Disease Journal最新文献_第8页

Characteristics, Risk Factors and Predictors for Candidemia in the Pediatric Intensive Care Unit at the University Hospital Centre Zagreb in Croatia: A 9-Year Retrospective Study. 克罗地亚萨格勒布大学医院中心儿科重症监护病房念珠菌病的特征、危险因素和预测因素:一项9年回顾性研究

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003225

Toni Matic, Milivoj Novak, Duje Braovac, Maja Vinkovic, Ana Marija Cicak, Milan Milosevic, Slobodan Galic, Miran Cvitkovic, Filip Rubic, Vanja Ille, Sanja Plesko

{"title":"Characteristics, Risk Factors and Predictors for Candidemia in the Pediatric Intensive Care Unit at the University Hospital Centre Zagreb in Croatia: A 9-Year Retrospective Study.","authors":"Toni Matic, Milivoj Novak, Duje Braovac, Maja Vinkovic, Ana Marija Cicak, Milan Milosevic, Slobodan Galic, Miran Cvitkovic, Filip Rubic, Vanja Ille, Sanja Plesko","doi":"10.1097/INF.0000000000003225","DOIUrl":"https://doi.org/10.1097/INF.0000000000003225","url":null,"abstract":"Background: Candidemia is one of the leading causes of bloodstream infections in the pediatric intensive care unit (PICU). The aim of this study was to define characteristics and risk factors for candidemia in the PICU setting and propose a predictive model to identify the patients at risk.Methods: This was a retrospective matched case-control study in the PICU during a 9-year period. Patients with candidemia were studied and matched with control patients without candidemia. Univariate analysis was performed for potential risk factors and multivariate analysis was conducted to determine the prediction score for candidemia.Results: Forty-two cases of candidemia were matched with 84 control patients. Candida parapsilosis was the most common (71.4%) species. Risk factors independently associated with candidemia were: the use of >2 antibiotics in a maximum period of 4 weeks before the candidemia (odds ratio [OR]: 10.59; 95% confidence interval [CI]: 2.05-54.83), a previous bacterial infection in a maximum period of 4 weeks before the candidemia (OR: 5.56; 95% CI: 1.44-21.5) and the duration of PICU stay of >10 days (OR: 4.22; 95% CI: 1.02-17.41). The proposed predictive scoring system has a sensitivity of 95.24%, specificity of 76.12%, OR 64.0, 95% CI 14.2-288.6, the positive predictive value of 66.67% and the negative predictive value of 96.97%.Conclusions: Previously reported risk factors for candidemia have been confirmed and some new have been detected. The presented scoring system can help identify patients who would benefit from prophylactic antifungal therapy.","PeriodicalId":118937,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":" ","pages":"981-986"},"PeriodicalIF":3.6,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39011141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Pneumococcal Serotype-specific Opsonophagocytic Activity in Interleukin-1 Receptor-associated Kinase 4-deficient Patients: ERRATUM. 白细胞介素-1受体相关激酶4缺陷患者肺炎球菌血清型特异性调理噬细胞活性:勘误。

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003375

引用次数: 0

Epidemiology of Invasive Haemophilus influenzae Serotype a Disease-United States, 2008-2017. 2008-2017年侵袭性流感嗜血杆菌a血清型疾病的流行病学研究

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003346

引用次数: 10

Amoebic, Pyogenic or Mixed? The More You Search, the More You Find! 阿米巴，化脓性还是混合性?你搜索的越多，你发现的就越多!

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003242

Rishi Bolia

引用次数: 0

Tic Disorder in an 8-Year-old Boy With Borreliosis. 8岁男孩伴疏螺旋体病的抽动障碍。

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003252

Burak Ozdemir, Gulsum Iclal Bayhan

引用次数: 0

Cytomegalovirus Infection Presenting as Severe Sepsis, Hepatitis, and Autoimmune Hemolytic Anemia in an Immunocompetent Child in Pediatric Intensive Care Unit. 儿童重症监护室中免疫功能正常儿童巨细胞病毒感染表现为严重败血症、肝炎和自身免疫性溶血性贫血。

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003250

Abhijit Choudhary, Ankit Mehta

引用次数: 3

Neisseria meningitidis Serogroup Z Meningitis in a Child With Complement C8 Deficiency and Potential Cross Protection of the MenB-4C Vaccine. 补体C8缺乏症儿童血清Z组脑膜炎与MenB-4C疫苗的潜在交叉保护

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003259

Bryan van den Broek, Jordy P M Coolen, Marien I de Jonge, Ronald de Groot, Stefanie S V Henriet, Jeroen D Langereis, Michiel van der Flier

引用次数: 0

Second Episode of Multisystem Inflammatory Syndrome in Children: Relapse, Rebound, or Recurrence? 儿童多系统炎症综合征第二次发作:复发、反弹还是复发?

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-11-01 DOI: 10.1097/INF.0000000000003249

Ravindra Shamrao Pawar, Vyankatesh Arun Tarkasband, Rupali Kapil Patil, Amar Vilas Naik

引用次数: 2

Defining Age-specific Relationships of Respiratory Syncytial Virus and Rhinovirus Species in Hospitalized Children With Acute Wheeze. 急性喘息住院儿童呼吸道合胞病毒和鼻病毒种类的年龄特异性关系

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-10-01 DOI: 10.1097/INF.0000000000003194

Stephen W C Oo, Siew-Kim Khoo, Des W Cox, Glenys Chidlow, Kimberley Franks, Franciska Prastanti, Yury A Bochkov, Meredith L Borland, Guicheng Zhang, James E Gern, David W Smith, Joelene A Bizzintino, Ingrid A Laing, Peter N Le Souëf

{"title":"Defining Age-specific Relationships of Respiratory Syncytial Virus and Rhinovirus Species in Hospitalized Children With Acute Wheeze.","authors":"Stephen W C Oo, Siew-Kim Khoo, Des W Cox, Glenys Chidlow, Kimberley Franks, Franciska Prastanti, Yury A Bochkov, Meredith L Borland, Guicheng Zhang, James E Gern, David W Smith, Joelene A Bizzintino, Ingrid A Laing, Peter N Le Souëf","doi":"10.1097/INF.0000000000003194","DOIUrl":"https://doi.org/10.1097/INF.0000000000003194","url":null,"abstract":"Background: Acute wheezing is one of the most common hospital presentations for young children. Respiratory syncytial virus (RSV) and rhinovirus (RV) species A, B and the more recently described species C are implicated in the majority of these presentations. However, the relative importance and age-specificities of these viruses have not been defined. Hence, this study aimed to establish these relationships in a large cohort of prospectively recruited hospitalized children.Methods: The study cohort was 390 children 0-16 years of age presenting with acute wheezing to a children's emergency department, 96.4% being admitted. A nonwheezing control population of 190 was also recruited. Nasal samples were analyzed for viruses.Results: For the first 6 months of life, RSV was the dominant virus associated with wheezing (P < 0.001). From 6 months to 2 years, RSV, RV-A and RV-C were all common but none predominated. From 2 to 6 years, RV-C was the dominant virus detected (50-60% of cases), 2-3 times more common than RV-A and RSV, RSV decreasing to be absent from 4 to 7 years. RV-B was rare at all ages. RV-C was no longer dominant in children more than 10 years of age. Overall, RV-C was associated with lower mean oxygen saturation than any other virus (P < 0.001). Controls had no clear age distribution of viruses.Conclusion: This study establishes a clear profile of age specificity of virus infections causing moderate to severe wheezing in children: RSV as the dominant cause in the first 6 months and RV-C in preschool-age children.","PeriodicalId":118937,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":" ","pages":"873-879"},"PeriodicalIF":3.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39254001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Neonatal Community-acquired Raoultella Ornithinolytica Septicemia: A Case Report and Review of the Literature. 新生儿社区获得性溶鸟拉乌尔氏菌败血症1例报告及文献复习。

IF 3.6

The Pediatric Infectious Disease Journal Pub Date : 2021-10-01 DOI: 10.1097/INF.0000000000003197

Deniz Yaprak, Mina Misirligil, Ali Dinç Bozat, Belma Saygili Karagol

{"title":"Neonatal Community-acquired Raoultella Ornithinolytica Septicemia: A Case Report and Review of the Literature.","authors":"Deniz Yaprak, Mina Misirligil, Ali Dinç Bozat, Belma Saygili Karagol","doi":"10.1097/INF.0000000000003197","DOIUrl":"https://doi.org/10.1097/INF.0000000000003197","url":null,"abstract":"Raoultella ornithinolytica is an opportunistic, aquaphilic and Gram-negative bacterium. Immune deficiency states and indwelling catheters provide a basis for most of the infections arising. R. ornithinolytica septicemia (ROS) is extremely rare in neonates but can be life threatening. Community-acquired ROS has not been described in neonates before. The diagnosis of neonatal septicemia is occasionally complicated by unusual clinical presentations. Pyloric stenosis is manifested by projectile, nonbilious vomiting and late findings, including weight loss, dehydration and electrolyte abnormalities beyond 4-6 weeks old. Community-acquired neonatal septicemia symptoms can sometimes be confused with symptoms of gastrointestinal obstructions in patients without risk factors for sepsis. Early diagnosis and appropriate antibiotics are essentials for a good prognosis in neonatal septicemia. Herein, we present a novel case of community-acquired ROS with an unusual presentation in a term infant and a review of the literature about ROS in the neonatal period.","PeriodicalId":118937,"journal":{"name":"The Pediatric Infectious Disease Journal","volume":" ","pages":"e370-e373"},"PeriodicalIF":3.6,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39183120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1