European Child & Adolescent Psychiatry最新文献_第3页

Replicating and extending the reliability, criterion validity, and treatment sensitivity of the shortened PANSS for pediatric trials.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-10 DOI: 10.1007/s00787-025-02681-1

Joan Busner, Eric A Youngstrom, Joshua A Langfus, David G Daniel, Robert L Findling

{"title":"Replicating and extending the reliability, criterion validity, and treatment sensitivity of the shortened PANSS for pediatric trials.","authors":"Joan Busner, Eric A Youngstrom, Joshua A Langfus, David G Daniel, Robert L Findling","doi":"10.1007/s00787-025-02681-1","DOIUrl":"https://doi.org/10.1007/s00787-025-02681-1","url":null,"abstract":"Do the shortened Positive and Negative Syndrome Scale (PANSS) (Kay et al., J Clin Psychiatry 58:538-546, 1987) versions recently developed from a National Institute of Mental Health (NIMH) pediatric dataset continue to perform well in a third independent randomized double-blind clinical trial of adolescents with schizophrenia? Secondary analysis of the double-blind, placebo-controlled aripiprazole pivotal trial data (N = 302) found that the 10-item (and 20-item) PANSS versions on which we have previously reported (Findling et al., J Am Acad Child Adolesc Psychiatry, https://doi.org/10.1016/j.jaac.2022.07.864 , 2023) continued to provide high reliability, strong convergent correlation with expected measures, and treatment effects that equaled those found in the 30-item adult PANSS. Our shortened PANSS, derived originally from the randomized non-placebo controlled NIMH Treatment of Early Onset Schizophrenia Spectrum study (TEOSS) (Sikich et al., Am J Psychiatry 165(11):1420-1431, 2008), and independently replicated in both the placebo-controlled paliperidone pivotal trial for adolescents with schizophrenia (Youngstrom et al., PsyArxiv, https://doi.org/10.31234/osf.io/zb695 , 2023), and now the placebo-controlled aripiprazole pivotal trial for adolescents with schizophrenia, has again performed as well as the full 30 item adult-patient derived PANSS. The findings suggest it is possible to reduce the PANSS interview by 2 thirds, thus reducing burden on families and pediatric patients as well as administration and training costs, while maintaining high reliability, validity, and sensitivity to treatment equal to that of the 30-item version.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socio-demographic and clinical characteristics associated with mental health-related support and service contact in children and young people aged 5-16 in England.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-08 DOI: 10.1007/s00787-025-02666-0

Samuel P Trethewey, Frances Mathews, Abigail Russell, Tamsin Newlove-Delgado

{"title":"Socio-demographic and clinical characteristics associated with mental health-related support and service contact in children and young people aged 5-16 in England.","authors":"Samuel P Trethewey, Frances Mathews, Abigail Russell, Tamsin Newlove-Delgado","doi":"10.1007/s00787-025-02666-0","DOIUrl":"10.1007/s00787-025-02666-0","url":null,"abstract":"Mental health problems are common in children and young people (CYP) in England, yet evidence suggests high levels of unmet need. Understanding of the determinants of mental health-related service contact is needed to identify gaps in provision and areas for targeted intervention to improve access. A secondary analysis of the Mental Health of Children and Young People in England 2017 (MHCYP-2017) cross-sectional survey dataset was performed. This analysis describes mental health-related support and service contact amongst a national stratified probability sample of 6681 participants aged 5-16. A range of socio-demographic and clinical characteristics were analysed as explanatory variables and their relationships with different types of support and service contact were examined through multivariable multinomial logistic regression. Analyses were stratified by age group: 5-10- and 11-16-year-olds. Analyses revealed strong associations between participant socio-demographic/clinical characteristics and mental health-related support and service contact, independent of CYP mental health status and parental perception of difficulties. Among these associations, socio-economically disadvantaged and Black, Asian and Minority Ethnic CYP were less likely to have had professional contact for mental health problems in both age groups. Findings suggest there may be higher levels of unmet need in socio-economically disadvantaged and Black, Asian and Minority Ethnic CYP, warranting further investigation and efforts to address inequalities.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between sexual victimization at age 14 and mental health and substance use outcomes at age 17.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-08 DOI: 10.1007/s00787-025-02670-4

Shannon Thompson, Mila Kingsbury, Nura Abuosba, Praveetha Patalay, Ian Colman

{"title":"Associations between sexual victimization at age 14 and mental health and substance use outcomes at age 17.","authors":"Shannon Thompson, Mila Kingsbury, Nura Abuosba, Praveetha Patalay, Ian Colman","doi":"10.1007/s00787-025-02670-4","DOIUrl":"10.1007/s00787-025-02670-4","url":null,"abstract":"Adolescent sexual violence is a serious public health concern that may have lasting impacts on the survivor, yet limited longitudinal research on the behavioural and mental health outcomes following sexual victimization exists. To describe the long-term behavioural and mental health outcomes associated with sexual victimization at 14 years of age, and whether these outcomes differed by sex, sexual orientation, and ethnic minority status. This prospective study used data from the Millennium Cohort Study, a nationally representative, longitudinal cohort study of children born in the United Kingdom between 2000 and 2002. Sexual victimization was self-reported when cohort members were 14 years of age, and outcomes (self-harm, suicide attempt, distress, alcohol use, binge drinking, smoking, vaping, and illicit substance consumption) were measured at age 17. Sexual victimization at age 14 was associated with poorer mental health, binge drinking, smoking regularly, vaping, and illicit drug use at age 17. Mental health outcomes differed by sex and these associations were stronger for males than females (self-harm: males RR = 2.4,95%CI: 1.55-3.79, females RR = 1.3,95%CI: 1.10-1.63; distress: males RR = 3.3,95%CI: 1.73-6.24, females RR = 1.4,95%CI: 1.08-1.75). Compared to non-victimized heterosexual adolescents, victimized heterosexual adolescents had nearly twice the risk of self-harm (RR = 1.87,95%CI: 1.40-2.46) and distress (RR = 2.09,95%CI: 1.46-2.96). Victimized adolescents belonging to an ethnic minority group showed three times the risk of distress (RR = 3.35,95%CI: 1.70-6.61) and non-ethnic minorities were more likely to vape (RR = 1.56, 95%CI:1.08-2.25). Adolescents who experience sexual victimization are at increased risk of poorer mental health later in adolescence.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of the risk of severe bacterial infection and septicemia in adolescents and young adults with treatment-resistant depression and treatment-responsive depression - a nationwide cohort study in Taiwan.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-08 DOI: 10.1007/s00787-025-02684-y

Jia-Ru Li, Yu-Chen Kao, Shih-Jen Tsai, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang, Mu-Hong Chen

{"title":"Comparative analysis of the risk of severe bacterial infection and septicemia in adolescents and young adults with treatment-resistant depression and treatment-responsive depression - a nationwide cohort study in Taiwan.","authors":"Jia-Ru Li, Yu-Chen Kao, Shih-Jen Tsai, Ya-Mei Bai, Tung-Ping Su, Tzeng-Ji Chen, Chih-Sung Liang, Mu-Hong Chen","doi":"10.1007/s00787-025-02684-y","DOIUrl":"10.1007/s00787-025-02684-y","url":null,"abstract":"Previous studies have shown an association between depression and increased susceptibility to infection in the general population. However, there has been no prior research specifically examining the relationship between treatment-resistant depression (TRD) and severe bacterial infections (SBI) in adolescents and young adults. This retrospective observational cohort study utilized the Taiwan National Health Insurance Research Database (NHIRD) from 2001 to 2010. It included adolescents (12-19 years of age) and young adults (20-29 years of age) diagnosed with major depressive disorder (MDD), comprising 6958 cases of TRD and 27,832 cases of antidepressant-responsive depression (ARPD). The TRD and ARPD groups were further matched (4:1) by chronological age, age at diagnosis of depression, sex, residence, and family income. The primary outcomes were severe bacterial infections (SBI) and septicemia. Cox regression analysis was conducted to identify the risk of hospitalization due to SBI or septicemia during the follow-up period. Compared with controls, the ARPD group had increased risks of SBI (hazard ratio [HR] with 95% confidence interval [CI]: 3.90, 2.73-5.57) and septicemia (HR, 95% CI: 2.56, 1.34-4.91). Notably, the risks of SBI and septicemia appeared to be further elevated in the TRD group. The TRD group exhibited higher incidences of SBI (HR, 95% CI: 6.99, 4.73-10.34) and septicemia (HR, 95% CI: 2.85, 1.28-6.36) than the control group. Adolescents and young adults with TRD had 6.99-fold and 3.90-fold increased risks of SBI and septicemia compared to individuals without MDD, respectively. Therefore, healthcare providers need to be vigilant when monitoring and implementing preventive measures in this population.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antidepressant treatment of depression in children and adolescents: a systematic review and dose-response meta-analysis.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-08 DOI: 10.1007/s00787-025-02688-8

Yuan Zhang, Yiyuan Gao, Xuelian Li, Yazhu Zou, Yu Ye, Zhili Zou

{"title":"Antidepressant treatment of depression in children and adolescents: a systematic review and dose-response meta-analysis.","authors":"Yuan Zhang, Yiyuan Gao, Xuelian Li, Yazhu Zou, Yu Ye, Zhili Zou","doi":"10.1007/s00787-025-02688-8","DOIUrl":"10.1007/s00787-025-02688-8","url":null,"abstract":"Pediatric major depressive disorder (MDD) often leads to recurrent depression in adulthood. The efficacy, safety and dose dependency of pharmacological effect is unclear. We conducted a systematic review and dose-response meta-analysis comprising of 22 double-blind randomized controlled trials, the majority of which had short trial durations ranging from 6 to 12 weeks. Studies were identified from PubMed, Ovid Embase, Ovid Medline, Ovid PsycInfo, Wanfang, ClinicalTrial.gov and CENTRAL until July 31, 2023. Doses of all antidepressants were converted to fluoxetine equivalents. Outcomes including treatment response, remission, suicidality, tolerability and acceptability were assessed. Sensitivity analysis, funnel plot and the trim-and fill method are used to assess and adjust for publication bias. Findings revealed that antidepressants were marginally more effective than placebos in terms of treatment response, but significantly increased the risk of adverse effects. No significant differences were observed in remission, suicidality, or overall dropout rates. Dose-response analysis indicated a relatively flat increase in response probability with higher fluoxetine equivalent doses, but also a sharp increase risk of discontinuation due to side effects. This study suggests that antidepressants for pediatric MDD may be less effective in adults, emphasizing the need to balance treatment benefits with potential adverse effects when considering interventions for this population.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143582200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the potential association between stimulant or atomoxetine use and suicidal or self-injurious behaviors in children with attention deficit hyperactivity disorder: real-world insights from the FAERS database.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-06 DOI: 10.1007/s00787-025-02694-w

Jinhua Liu, Liping Xue, Fanxiang Zeng, Ying Liu, Yanting Zhu, Jintuo Zhou, Jinhua Zhang, Huajiao Chen

{"title":"Exploring the potential association between stimulant or atomoxetine use and suicidal or self-injurious behaviors in children with attention deficit hyperactivity disorder: real-world insights from the FAERS database.","authors":"Jinhua Liu, Liping Xue, Fanxiang Zeng, Ying Liu, Yanting Zhu, Jintuo Zhou, Jinhua Zhang, Huajiao Chen","doi":"10.1007/s00787-025-02694-w","DOIUrl":"https://doi.org/10.1007/s00787-025-02694-w","url":null,"abstract":"This study aims to investigate the potential correlation between commonly prescribed attention-deficit/hyperactivity disorder (ADHD) medications and suicidal or self-injurious behaviors (SSIBs) among the pediatric population by exploring the FDA Adverse Event Reporting System (FAERS) database. The FAERS database (2004Q1-2023Q4) was queried and SSIBs cases associated with stimulants (methylphenidate, and amphetamine) or atomoxetine were identified. The signals for SSIBs were analyzed using disproportionate methods, and the accuracy of the results was validated through sensitivity analysis with multifactor logistic regression. Time-to-onset analysis explored factors affecting SSIBs manifestation. Disproportionality analysis revealed a significant negative association between methylphenidate and SSIBs, while atomoxetine exhibited a significant positive correlation with SSIBs. The frequency of SSIBs was lower with stimulants alone or with the combined use of stimulants and atomoxetine compared to atomoxetine alone. Time-to-onset analysis indicated that all cases were of the early failure type, with the median time to onset of SSIBs associated with atomoxetine occurring later than that linked to stimulants. Stratification by age showed that in the stimulant group, the median time to SSIBs was longer for patients aged 13-17 years compared to those aged 6-12 years. Conversely, the opposite trend was observed in the atomoxetine group. The observed differences in time to onset highlight the importance of individualized screening for SSIBs across various populations, ultimately improving patient outcomes in the follow-up of stimulants or atomoxetine recipients.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Internet gaming disorder and suicidal behaviors mediated by sleep disturbance: a large-scale school-based study in 135,174 Chinese middle school students.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-03 DOI: 10.1007/s00787-025-02675-z

Pu Peng, Zhangming Chen, Silan Ren, Yi Liu, Jinguang Li, Aijun Liao, Linlin Zhao, Ruini He, Yudiao Liang, Youguo Tan, Jinsong Tang, Xiaogang Chen, Yanhui Liao

{"title":"Internet gaming disorder and suicidal behaviors mediated by sleep disturbance: a large-scale school-based study in 135,174 Chinese middle school students.","authors":"Pu Peng, Zhangming Chen, Silan Ren, Yi Liu, Jinguang Li, Aijun Liao, Linlin Zhao, Ruini He, Yudiao Liang, Youguo Tan, Jinsong Tang, Xiaogang Chen, Yanhui Liao","doi":"10.1007/s00787-025-02675-z","DOIUrl":"https://doi.org/10.1007/s00787-025-02675-z","url":null,"abstract":"Emerging research suggests a positive association between Internet gaming disorder (IGD) and suicidal behaviors. However, existing studies predominantly focus on suicidal ideation rather than suicide attempts and often do not adequately control for potential psychological confounders. The mechanism linking IGD to suicidality remains unclear. This study aims to assess the independent association between IGD and suicidal behaviors and to examine the mediating role of sleep disturbance among Chinese adolescents. We recruited 135,174 middle school students from Zigong City using cluster sampling. Data on demographics, suicidal ideation, and suicidal attempts were collected. IGD was assessed using the Internet Gaming Disorder Scale-Short Form. Mental distress, including depression, anxiety, hyperactivity/inattention, conduct problems, sleep problems, and psychotic experiences, was evaluated using standardized questionnaires. Multiple logistic regression models and mediation analysis were conducted. The prevalence rates of IGD, suicidal behaviors, suicidal ideation, and suicide attempts were 1.6%, 16.7%, 11.9%, and 9.8%, respectively. Adolescents with IGD showed a significantly higher risk for suicidality: nearly 60% reported suicidal behaviors, 50% reported suicidal ideation, and 40% reported suicide attempts. Both IGD and gaming usage were independently linked to suicidal behaviors. Sleep disturbance partially mediated the relationship between IGD and suicidal behaviors, accounting for 47.0% of the total effect. Our studies call for timely and regular assessments for suicidality and sleep disturbance in IGD. Targeted interventions addressing sleep disturbance might reduce suicidal risk among adolescents with IGD.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence, severity and risk factors for mental disorders among sexual and gender minority young people: a systematic review of systematic reviews and meta-analyses. 性少数群体和性别少数群体青少年精神障碍的患病率、严重程度和风险因素：系统综述和荟萃分析。

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-01 Epub Date: 2024-08-14 DOI: 10.1007/s00787-024-02552-1

Jonathan O'Shea, Rebecca Jenkins, Dasha Nicholls, James Downs, Lee D Hudson

{"title":"Prevalence, severity and risk factors for mental disorders among sexual and gender minority young people: a systematic review of systematic reviews and meta-analyses.","authors":"Jonathan O'Shea, Rebecca Jenkins, Dasha Nicholls, James Downs, Lee D Hudson","doi":"10.1007/s00787-024-02552-1","DOIUrl":"10.1007/s00787-024-02552-1","url":null,"abstract":"Evidence suggests heightened prevalence and severity of mental disorders among sexual minority (SM) and gender minority (GM) young people. Several risk factors have been associated with these disparities. A systematic review of systematic reviews and meta-analysis was conducted to provide a comprehensive overview of the literature and to determine the field's current position. MEDLINE, PsycInfo, Scopus and Web of Science were searched in March 2022 and updated January 2024. Eligibility criteria were systematic reviews or meta-analyses assessing contemporaneous prevalence, severity and/or risk factors of mental disorders among SM or GM young people aged 25 and under. 42 reviews were included, all of which were low quality. The prevalence of depression among SM was 26% (95% CI 21-32%), and among GM was 46% (95% CI 36-56%). Greater depression severity was found among SM compared to heterosexual young people, with a significant albeit small effect size (Hedges' g = 0.38, 95% CI = 0.25 to 0.50); effect sizes were similar when separating by gender. GM also reported greater symptom severity compared to cisgender young people. Other mental disorders were more prevalent compared to those reported in the general population, and of greater severity compared to heterosexual/cisgender young people. Several proximal and distal risk factors were focused upon within the systematic reviews identified. Past systematic reviews consistently indicate a heightened risk of mental disorders among SM and GM young people. Services need to be aware of these disparities and adapt their care accordingly.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":"959-982"},"PeriodicalIF":6.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating European contexts and needs into WHO guiding principles on online mental health content for young people: five recommendations. 将欧洲背景和需求纳入世卫组织关于青少年在线心理健康内容的指导原则：五项建议。

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-01 Epub Date: 2024-08-29 DOI: 10.1007/s00787-024-02566-9

Helena Ludwig-Walz, Martin Bujard, Jonas Fegert, Jörg M Fegert

引用次数: 0

The association between junk foods consumption and attention deficit hyperactivity disorder in children and adolescents: a systematic review and meta-analysis of observational studies. 儿童和青少年食用垃圾食品与注意力缺陷多动障碍之间的关系：观察性研究的系统回顾和荟萃分析。

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-01 Epub Date: 2024-07-22 DOI: 10.1007/s00787-024-02521-8

Maryam Khazdouz, Reza Safarzadeh, Bahram Hejrani, Motahareh Hasani, Fatemeh Sadat Mahdavi, Hanieh-Sadat Ejtahed, Mostafa Qorbani

{"title":"The association between junk foods consumption and attention deficit hyperactivity disorder in children and adolescents: a systematic review and meta-analysis of observational studies.","authors":"Maryam Khazdouz, Reza Safarzadeh, Bahram Hejrani, Motahareh Hasani, Fatemeh Sadat Mahdavi, Hanieh-Sadat Ejtahed, Mostafa Qorbani","doi":"10.1007/s00787-024-02521-8","DOIUrl":"10.1007/s00787-024-02521-8","url":null,"abstract":"The adverse effects of junk foods on the risk of attention deficit hyperactivity disorder (ADHD) symptoms were reported in several studies. In this meta-analysis, the association between junk food consumption and the risk of ADHD was investigated in children and adolescents. A comprehensive systematic search was conducted to find all relevant literature via four databases, including PubMed, Web of Science, Scopus, and Google scholar, up to September 2022. Two independent authors screened all documents based on inclusion criteria. The overall effect sizes and related 95% confidence interval (CI) were pooled with the random effect approach. Subgroup analysis was done to measure potential sources of heterogeneity between studies. The quality of the included studies was evaluated with The Newcastle-Ottawa scale (NOS). Nine observational studies with 58,296 children /adolescents were eligible to be include in the meta-analysis. According to the random effect model, there was a positive relation between the consumption of junk foods and ADHD symptoms (odds ratio (OR): 1.24, 95%CI 1.15-1.34, P < 0.001, I2: 37.4%, P = 0.085). A similar significant positive association was shown in the subgroups analysis by different junk foods (sweetened beverages/soft drinks, sweets/candies, and other types of junk foods). This meta-analysis finding demonstrated that consuming junk foods, especially sweetened beverages/soft drinks, and sweets/candies is associated with ADHD symptoms.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":"825-834"},"PeriodicalIF":6.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0