European Child & Adolescent Psychiatry最新文献

Neural effect of childhood maltreatment on neurovascular coupling in adolescent depression.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-04-03 DOI: 10.1007/s00787-025-02708-7

Sangni Liu, Dandan Fan, Cancan He, Xinyi Liu, Haisan Zhang, Hongxing Zhang, Zhijun Zhang, Chunming Xie, PingLei Pan

{"title":"Neural effect of childhood maltreatment on neurovascular coupling in adolescent depression.","authors":"Sangni Liu, Dandan Fan, Cancan He, Xinyi Liu, Haisan Zhang, Hongxing Zhang, Zhijun Zhang, Chunming Xie, PingLei Pan","doi":"10.1007/s00787-025-02708-7","DOIUrl":"https://doi.org/10.1007/s00787-025-02708-7","url":null,"abstract":"Childhood maltreatment (CM) is a pivotal risk factor for depression, yet its potential contribution to major depressive disorder (MDD) in adolescents requires further investigation. This study aims to scrutinize the specific impact of CM on neurovascular coupling (NVC) in adolescents with MDD. A cohort of 189 adolescents, comprising 54 MDD with CM, 45 MDD without CM, 33 healthy controls (HC) with CM, and 57 HC without CM, underwent multimodal MRI scans. Cerebral blood flow (CBF) was computed to evaluate vascular responses, while functional connectivity strength (FCS) and amplitude of low-frequency fluctuation (ALFF) were measured to assess neuronal activity. NVC was calculated using whole gray matter CBF-neuronal activity correlation coefficients and regional CBF/neuronal activity ratios. MDD×CM interactions on NVC, CBF, and neuronal activity were analyzed, with further exploration of the associations between these abnormal NVC ratios and CM experience. Support vector machine classifiers were employed to differentiate MDD adolescents. Results revealed a significant MDD×CM interactive effect on CBF-FCS coefficients at whole gray matter level. Regionally, these interactions on NVC ratios primarily occurred in the reward systems, including bilateral anterior cingulate/orbitofrontal cortex, thalamus/mesial temporal lobe, and left occipitotemporal lobe, correlating with CM measurements. Notably, the integration of NVC ratio, CBF, and neuronal activity yielded robust classification performance in distinguishing MDD adolescents. These findings reinforce the importance of reward system for MDD adolescents related to CM, proposing a novel neuroimaging biomarker for early recognition of adolescent depression.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143771595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Family and parenting factors are associated with emotion regulation neural function in early adolescent girls with elevated internalizing symptoms.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-04-01 DOI: 10.1007/s00787-025-02692-y

Sylvia C Lin, Elena Pozzi, Christiane E Kehoe, Sophie Havighurst, Orli S Schwartz, Marie B H Yap, Junxuan Zhao, Eva H Telzer, Sarah Whittle

引用次数: 0

Effects of social skills training on social responsiveness of people with Autism spectrum disorder: a systematic review with meta-analysis. 社交技能培训对自闭症谱系障碍患者社交反应能力的影响：系统回顾与荟萃分析。

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-28 DOI: 10.1007/s00787-025-02697-7

Marcos Vinicio Anchieta, Nelson Torro-Alves, Égina Karoline Gonçalves da Fonsêca, Flávia de Lima Osório

{"title":"Effects of social skills training on social responsiveness of people with Autism spectrum disorder: a systematic review with meta-analysis.","authors":"Marcos Vinicio Anchieta, Nelson Torro-Alves, Égina Karoline Gonçalves da Fonsêca, Flávia de Lima Osório","doi":"10.1007/s00787-025-02697-7","DOIUrl":"https://doi.org/10.1007/s00787-025-02697-7","url":null,"abstract":"Social skills training (SST) is a widely proposed intervention to address social impairments in autism spectrum disorder (ASD). SST employs a series of activities aiming to enhance pro-social behaviors. A promising approach to evaluate SST's effects lays on social responsiveness (SR) indicators, which are related to the capacity to respond appropriately to social stimuli. Despite the widespread use of SST, there are no integrative studies evaluating its effects on the SR of ASD people. We performed a systematic review with meta-analysis investigating the effects of SSTs in SR indicators of individuals with ASD. PRISMA guidelines were considered to search through EMBASE, PubMed, PsycINFO, and Scopus without timeframes or language restrictions. Randomized controlled trials (RCTs) were included only. Jamovi (version 1.6) was used to perform the meta-analysis with the standardized mean difference (SMD) between pre and post-intervention scores (∆) as the outcome measure. Twenty-seven papers composed the review and 25 the meta-analysis. The population was predominantly male (80%), with a mean age of 13.03 years. Interventions were mostly conducted in group settings. Meta-analysis indicated the set of interventions as capable of improving SR indicators of ASD people (SMD = 0.57 (CI 95% 0.46-0.67; p < 0.0001). Although our findings cannot support PEERS program as quantitatively superior to other programs, its methodological consistency, treatment adherence and involvement of parents are noteworthy. SST appears to be a viable, versatile, and easily implementable intervention to improve SR of individuals with ASD.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From child sexual abuse to psychiatric diagnoses and complex trauma in adolescence. 从儿童性虐待到青春期的精神诊断和复杂创伤。

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-28 DOI: 10.1007/s00787-025-02682-0

Marine Rousset, Aziz Essadek, Maurice Corcos, Marion Robin

{"title":"From child sexual abuse to psychiatric diagnoses and complex trauma in adolescence.","authors":"Marine Rousset, Aziz Essadek, Maurice Corcos, Marion Robin","doi":"10.1007/s00787-025-02682-0","DOIUrl":"https://doi.org/10.1007/s00787-025-02682-0","url":null,"abstract":"CSA (Childhood Sexual Abuse) represents a major health issue, however its detection in daily psychiatric practice is remains challenging. In adolescents, CSA often takes a back seat to diagnostic and behavioral issues such as suicide attempts and BPD (Borderline Personality Disorder), with which it is frequently associated. Additionally, confusion persists between the perspective of complex trauma and conventional psychiatric diagnoses. This study aimed to compare clinical features of hospitalized adolescents with a history of CSA, to a control group, in order to identify clinical predictors of CSA and of suicidal attempts. The secondary objective was to describe the overlap between PTSD (Post Traumatic Stress Disorder) and BPD, according to cumulative adversity. This study included 425 adolescents aged 13 to 19 years, who were hospitalized in a psychiatric unit. Among these adolescents, 107 had a history of CSA. The findings indicate that CSA plays a significant role in the psychopathology of adolescents. CSA was found to be associated with PTSD, BPD (OR = 1.9, p < 0.01), self-harm (OR = 1.8, p < 0.05), addictive disorders (OR = 1.87, p < 0.05), and parental neglect (p < 0,001). Suicide attempts were also significantly correlated with sexual abuse (OR = 1.78, p < 0.05). Moreover, the combination of factors such as female gender, the presence of BPD, and substance dependence was found to increase the likelihood of a history of sexual abuse in these adolescents by 14.8 times. These findings contribute to the early detection of sexual violence and its consequences, providing valuable insights for healthcare professionals. Additionally, they support the reinforcement of preventive initiatives.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prefrontal-hippocampal pathways underlying adolescent resilience.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-28 DOI: 10.1007/s00787-025-02704-x

Luqing Wei, Zhengdong Wu, Qi Xia, Chris Baeken, Guo-Rong Wu

{"title":"Prefrontal-hippocampal pathways underlying adolescent resilience.","authors":"Luqing Wei, Zhengdong Wu, Qi Xia, Chris Baeken, Guo-Rong Wu","doi":"10.1007/s00787-025-02704-x","DOIUrl":"https://doi.org/10.1007/s00787-025-02704-x","url":null,"abstract":"The prefrontal-hippocampal pathways are integral to memory suppression, facilitating positive and adaptative responses following traumatic events. However, the role of these circuits in promoting resilience among adolescents remains largely unknown. This study used structural similarity analysis of MRI-based gray matter volume (GMV) to map connectivity networks centered on the hippocampus, investigating whether structural similarity between prefrontal regions and hippocampus were related to resilience in a cohort of 145 adolescents. Additionally, spatial correlation analyses of resilience-related structural similarity network and neurotransmitter distribution maps were conducted to identify molecular adaptations within prefrontal-hippocampal circuits associated with resilience. The results showed that higher resilience levels were correlated with stronger structural similarity between the prefrontal areas (i.e., middle frontal gyrus and orbitofrontal cortex) and hippocampus. Furthermore, the serotonergic neurotransmitter system, which modulates neural oscillations in prefrontal-hippocampal pathways, appears to be associated with resilience. The current findings suggest that structural and molecular adaptations within prefrontal-hippocampal circuits, which are implicated in the suppression of intrusive, unwanted memories, may foster resilience in young people. These insights advance our knowledge of the neurobiological markers of resilience, paving the way for more targeted and effective therapeutic interventions to bolster resilience and mitigate adverse outcomes in developmental populations.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal attitudes and child mental health across cultures: a European /Chinese comparison.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-27 DOI: 10.1007/s00787-025-02699-5

Viviane Kovess-Masfety, Nathalie Touma, Guoli Yan, Huifang Yin, Dietmar Goelitz, Adina Bitfoi, Sigita Lesinskiene, Zlatka Mihova, Roy Otten, Guangming Xu

{"title":"Maternal attitudes and child mental health across cultures: a European /Chinese comparison.","authors":"Viviane Kovess-Masfety, Nathalie Touma, Guoli Yan, Huifang Yin, Dietmar Goelitz, Adina Bitfoi, Sigita Lesinskiene, Zlatka Mihova, Roy Otten, Guangming Xu","doi":"10.1007/s00787-025-02699-5","DOIUrl":"https://doi.org/10.1007/s00787-025-02699-5","url":null,"abstract":"This study sought to identify factors associated with parenting across Western Europe, Eastern Europe and China countries, and determine whether the associations between parental attitudes and child's mental health differ across countries. This cross-sectional study included mothers and their children. European data were drawn from the School Child Mental Health in Europe study, conducted in the Netherlands, Germany, Lithuania, Bulgaria and Romania, including 4104 dyads. Chinese data were collected from the Dongli District of Tianjin, including 1000 dyads. Parental attitudes were auto reported using Parenting Scale and Parent Behavior and Attitude Questionnaire. Children's mental health was auto reported using the Dominic Interactive. Parenting vary across cultures and impact children's mental health differently. Whatever the parental attitudes, the main determinants were related to family configuration, parental well-being and place of residence. Some associations were culture-specific: parent's distress associated with laxness, over-reactivity and low autonomy-promoting attitudes in Europe. Single parenting correlated with low autonomy-promoting attitudes in China but low caring in Western Europe. Urban parents exhibited less laxness and low caring in Eastern Europe. The impact on children's mental health also varied: over-reactivity was linked to internalized and externalized disorders in Western Europe, verbosity associated with internalized and externalized disorders in China, and low caring was linked to externalized disorders in Eastern Europe. Parental diverse attitudes are associated with different children mental health problems; these associations are not identical in the different regions emphasizing the need to tailor existing supporting parental interventions with a culturally sensitive approach.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of exercise interventions on core symptoms of 3-12-year-old children with autism spectrum disorder: a systematic review and network meta-analysis.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-25 DOI: 10.1007/s00787-025-02696-8

Liu Zhang, Chi Zhang, Xin Yuan, Yuelong Ji

{"title":"The impact of exercise interventions on core symptoms of 3-12-year-old children with autism spectrum disorder: a systematic review and network meta-analysis.","authors":"Liu Zhang, Chi Zhang, Xin Yuan, Yuelong Ji","doi":"10.1007/s00787-025-02696-8","DOIUrl":"https://doi.org/10.1007/s00787-025-02696-8","url":null,"abstract":"Exercise interventions targeting Fundamental Movement Skills (FMS) represent a critical approach for mitigating functional impairments in children with autism spectrum disorder (ASD). This study, for the first time, based on motor development theory, employed a Network Meta-analysis (NMA) to examine the effects of four types of exercise interventions-Isolation of Fundamental Movement Skills (FMS-I), Combination of Fundamental Movement Skills (FMS-C), Fine Motor Movement (FMM), and Specialized Movement Skills (SMS)-on the core symptoms of ASD in children aged 3-12, including social communication deficits and stereotyped and repetitive behaviors. Five electronic databases were systematically searched up to May 22, 2024. Included studies compared exercise interventions with control groups and assessed at least one core symptom of ASD. Study quality and evidence certainty were evaluated using the Risk of Bias tools (RoB 2.0, ROBINS-I) and the Confidence in Network Meta-Analysis (CINeMA) framework. Data analysis was performed via Stata 17.0 software. The systematic review included 26 studies encompassing 878 children, with 19 studies eligible for NMA. Ranking probabilities indicated that FMS-I emerged as the most promising intervention for addressing social communication deficits (SMD: -0.99, 95%CI: -1.46 to -0.52; SUCRA: 86.9%) and stereotyped and repetitive behaviors (SMD: -2.73, 95% CI: -3.76 to -1.70; SUCRA: 100%). The FMS-C showed potential for enhancing overall features (SMD: -0.90; 95%CI: -1.32 to -0.49; SUCRA: 74.7%). To conclude, exercise interventions should be grounded in FMS, transitioning from isolated movements to integrated actions, to enhance the overall behavior of children with ASD.","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "temporal and spatial variability of large-scale dynamic brain networks in ASD".

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-21 DOI: 10.1007/s00787-025-02695-9

Amnuay Kleebayoon, Viroj Wiwanitkit

引用次数: 0

From haze to horizon: epigenetic research and artificial intelligence in child and adolescent psychiatry.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-20 DOI: 10.1007/s00787-025-02686-w

Yulia Golub, Antje Wulff, Torsten Plösch

引用次数: 0

Correction: Treatment failure in persistent tic disorders: an expert clinicians' consensus-based definition.

IF 6 2区医学

European Child & Adolescent Psychiatry Pub Date : 2025-03-20 DOI: 10.1007/s00787-024-02633-1

Davide Martino, Irene Malaty, Kirsten Müller-Vahl, Elaheh Nosratmirshekarlou, Tamara M Pringsheim, David Shprecher, Christos Ganos

引用次数: 0