European Child & Adolescent Psychiatry最新文献

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Correction: Associations between academic achievement and internalizing disorders in Swedish students aged 16 years between 1990 and 2018. 更正:1990至2018年间瑞典16岁学生学习成绩与内化障碍之间的关系。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-20 DOI: 10.1007/s00787-024-02617-1
Björn Högberg, Mattias Strandh, Solveig Petersen, Karina Nilsson
{"title":"Correction: Associations between academic achievement and internalizing disorders in Swedish students aged 16 years between 1990 and 2018.","authors":"Björn Högberg, Mattias Strandh, Solveig Petersen, Karina Nilsson","doi":"10.1007/s00787-024-02617-1","DOIUrl":"https://doi.org/10.1007/s00787-024-02617-1","url":null,"abstract":"","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A nomogram for predicting non-suicide self-injury in youth depression patients: a longitudinal analysis. 预测青少年抑郁症患者非自杀性自伤的提名图:纵向分析。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-18 DOI: 10.1007/s00787-024-02603-7
Yingwen Li, Yarong Ma, Bin Sun, Robert Rosenheck, Jie Zhang, Hongbo He
{"title":"A nomogram for predicting non-suicide self-injury in youth depression patients: a longitudinal analysis.","authors":"Yingwen Li, Yarong Ma, Bin Sun, Robert Rosenheck, Jie Zhang, Hongbo He","doi":"10.1007/s00787-024-02603-7","DOIUrl":"https://doi.org/10.1007/s00787-024-02603-7","url":null,"abstract":"<p><p>Non-suicidal self-injury (NSSI) behavior is a common issue in youth with depression while lacks a prognostic prediction model. This study aims to develop a nomogram for NSSI in youth with depression. A total of 701 patients were included in the analysis based a youth depression cohort. They were further divided into a training set and a validation set. The Lasso regression and binary logistic regression were used to select variables for the nomogram. The nomogram's discrimination, calibration, accuracy, clinical applicability, and generalization involved the use of metrics such as the area under the receiver operating characteristic curve (ROC), Hosmer-Lemeshow (HL) test, Brier score, calibration curve, decision curve analysis (DCA), and internal validation. The Delong test was employed to compare the ROC performance between the two models. These patients had an average age of 19.3+/-3.3 years, and 101 (20.6%) individuals reported NSSI. Five risk factors for NSSI were identified: age, age at first medication, previous instances of NSSI, academic stress score in the Adolescent Self-rating Life Events Check List (ASLEC), and somatic anxiety of the 14 item Hamilton Anxiety Rating Scale (HAMA-14). The training set and validation set of binary logistic regression-based model showed good discrimination (area under the curve (AUC) 0.781, 95% CI: 0.735 ~ 0.827; and 0.757, 95% CI: 0.682 ~ 0.831, respectively), calibration (P = 0.421 and 0.175, respectively), and accuracy (Brier score 0.119 to 0.155 and 0.109 to 0.168, respectively). A prognostic nomogram was developed and validated to assist clinicians in predicting NSSI of youth with depression.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The patient and the family: investigating parental mental health problems, family functioning, and parent involvement in child and adolescent mental health services (CAMHS). 病人与家庭:调查父母的心理健康问题、家庭功能以及父母参与儿童和青少年心理健康服务(CAMHS)的情况。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-18 DOI: 10.1007/s00787-024-02607-3
Emme-Lina Wirehag Nordh, Karin Grip, Ulf Axberg
{"title":"The patient and the family: investigating parental mental health problems, family functioning, and parent involvement in child and adolescent mental health services (CAMHS).","authors":"Emme-Lina Wirehag Nordh, Karin Grip, Ulf Axberg","doi":"10.1007/s00787-024-02607-3","DOIUrl":"https://doi.org/10.1007/s00787-024-02607-3","url":null,"abstract":"<p><p>Parental mental health problems can impact child mental health, as well as treatment of child mental health problems. The aim of this study was to investigate self-reported mental health problems in parents of children referred to outpatient child and adolescent mental health services (CAMHS) and to compare child mental health problems, family variables, treatment received and parent participation in treatment planning between parents above and below the cut-off for elevated mental health problems. The sample included N = 111 parents of N = 98 children. Parental reports covering their own and their children's mental health problems, family functioning, adult relationship satisfaction, and previous treatment for mental health problems were collected at the time of the child's intake appointment. Questions concerning contact with CAMHS were completed one year later. At the time of the intake appointment, 44% of the children had a parent who reported elevated mental health problems. In these families, children reportedly had significantly more mental health problems and problematic family functioning was more common than in families where parent mental health problems were not elevated. Parents with elevated mental health problems received group-based parent support/education to a greater extent during the first year of contact with CAHMS and reported less participation in treatment planning compared to parents without elevated mental health problems. To conclude, findings indicate that co-occurring mental health problems are common in parents when their child is referred to CAMHS, and in these families, it is reported that children have more symptoms, and more families experience problematic functioning. These factors merit consideration in assessment and treatment planning, indicating increased treatment needs in this group of families.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental health, risk behaviors, and social life factors in relation to adolescents' suicide ideation, plans and attempt. 心理健康、危险行为和社会生活因素与青少年自杀意念、计划和企图自杀的关系。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-15 DOI: 10.1007/s00787-024-02616-2
Stine Danielsen, Katrine Strandberg-Larsen, Massimiliano Orri, Merete Nordentoft, Annette Erlangsen, Trine Madsen
{"title":"Mental health, risk behaviors, and social life factors in relation to adolescents' suicide ideation, plans and attempt.","authors":"Stine Danielsen, Katrine Strandberg-Larsen, Massimiliano Orri, Merete Nordentoft, Annette Erlangsen, Trine Madsen","doi":"10.1007/s00787-024-02616-2","DOIUrl":"https://doi.org/10.1007/s00787-024-02616-2","url":null,"abstract":"<p><strong>Objective: </strong>This study investigated differences in mental health and well-being, risk behaviors, and social life factors among adolescents who experienced different forms of suicidality.</p><p><strong>Methods: </strong>We examined 18-years-olds in the Danish National Birth Cohort (N = 47,852). Suicidality was defined with mutually exclusive categories ranging from no suicidality, self-reported suicide ideation, plans, and attempt as well as hospital-recorded suicide attempt. The proportion of adolescents with self-reported poor mental health and well-being, risk behaviors, and social life factors were compared across forms of suicidality. Sample weights were applied.</p><p><strong>Results: </strong>Depressive symptoms were reported by 14% (95% CI 13%;14%) of girls with no suicidality, 44% (95% CI 43%;45%) of girls with suicide ideation, and 68% (95% CI 65%;72%) 66% (95% CI 60%;72%) of girls with self-reported suicide attempt or hospital-recorded suicide attempt respectively. Among boys, depressive symptoms were reported by 5% (95% CI 4%;5%) of those with no suicidality, 27% (95% CI 26%;28%) of those with suicide ideation, and 51% (95% CI 45%;57%) and 40% (95% CI 22%;58%) of those with self-reported suicide attempt or hospital-recorded suicide attempt respectively. Likewise, other aspects of poor mental health and well-being gradually increased relative with more severe forms of suicidality, while no notable differences were identified between adolescents with self-reported and hospital-recorded suicide attempt. Similar tendencies were observed for risk behaviors and social life factors.</p><p><strong>Conclusion: </strong>These findings suggest that adolescents with suicidality, including the large proportion with suicide ideation only, faces challenges across several parameters of mental health and well-being, risk behavior, and social life factors. This emphasizes the need for community-based interventions to identify and support the large group of adolescents experiencing both more and less severe forms of suicidality. Clinicians should prioritize comprehensive psychiatric intervention to address the complex needs of suicidal adolescents effectively.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acceptance and commitment therapy as a transdiagnostic approach to adolescents with different anxiety disorders: study protocol. 将接纳与承诺疗法作为一种跨诊断方法,用于治疗患有不同焦虑症的青少年:研究方案。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-14 DOI: 10.1007/s00787-024-02608-2
Diana Vieira Figueiredo, Maria do Céu Salvador, Daniel Rijo, Paula Vagos
{"title":"Acceptance and commitment therapy as a transdiagnostic approach to adolescents with different anxiety disorders: study protocol.","authors":"Diana Vieira Figueiredo, Maria do Céu Salvador, Daniel Rijo, Paula Vagos","doi":"10.1007/s00787-024-02608-2","DOIUrl":"10.1007/s00787-024-02608-2","url":null,"abstract":"<p><p>Adolescence increases vulnerability to mental ill-health, particularly anxiety disorders like Social Anxiety Disorder (SAD) and Generalized Anxiety Disorder (GAD). Still, the understanding of Psychological Flexibility/Inflexibility (PF/PI) as a transdiagnostic framework relevant to explaining these difficulties and the efficacy of Acceptance and Commitment Therapy (ACT) in addressing adolescent SAD and GAD remains limited. Hence, this study has two aims: examining the role of PI/PF on adolescents' mental health and assessing ACT's efficacy for adolescent SAD and GAD. We will collect data from 400 community adolescents and employ network analysis to explore connections between PI/PF processes, anxiety, and flourishing. We will also investigate pathways linking PI/PF processes with flourishing and anxiety across samples (clinical SAD, clinical GAD, and mentally healthy groups), expecting to find similar patterns. Furthermore, a Randomized Controlled Trial with three groups (control, SAD experimental and GAD experimental), each comprising 29 participants, and four assessment moments (pre- and post-intervention and 3- and 6-months follow-up) will be conducted. Similar improvements are anticipated in both experimental groups, driven by changes in PI/PF processes. Findings from this work will provide valuable evidence to PI/PF as accurate conceptualizations of human suffering and expand the transdiagnostic application of ACT to adolescents with anxiety disorders.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing the mental health of families living with autism spectrum disorder: insights and future directions. 解决自闭症谱系障碍患者家庭的心理健康问题:见解与未来方向。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-14 DOI: 10.1007/s00787-024-02611-7
Lizhen Huang, Mingbang Wang, Wenxian Huang, Minyu Zhang, Wei He
{"title":"Addressing the mental health of families living with autism spectrum disorder: insights and future directions.","authors":"Lizhen Huang, Mingbang Wang, Wenxian Huang, Minyu Zhang, Wei He","doi":"10.1007/s00787-024-02611-7","DOIUrl":"https://doi.org/10.1007/s00787-024-02611-7","url":null,"abstract":"","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stimulant medication and symptom interrelations in children, adolescents and adults with attention-deficit/hyperactivity disorder. 患有注意力缺陷/多动症的儿童、青少年和成人的兴奋剂药物治疗与症状之间的相互关系。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-11 DOI: 10.1007/s00787-024-02610-8
Zarah van der Pal, Hilde M Geurts, Jonas M B Haslbeck, Alex van Keeken, Anne Marijn Bruijn, Linda Douw, Daan van Rooij, Barbara Franke, Jan Buitelaar, Nanda Lambregts-Rommelse, Catharina Hartman, Jaap Oosterlaan, Marjolein Luman, Liesbeth Reneman, Pieter J Hoekstra, Tessa F Blanken, Anouk Schrantee
{"title":"Stimulant medication and symptom interrelations in children, adolescents and adults with attention-deficit/hyperactivity disorder.","authors":"Zarah van der Pal, Hilde M Geurts, Jonas M B Haslbeck, Alex van Keeken, Anne Marijn Bruijn, Linda Douw, Daan van Rooij, Barbara Franke, Jan Buitelaar, Nanda Lambregts-Rommelse, Catharina Hartman, Jaap Oosterlaan, Marjolein Luman, Liesbeth Reneman, Pieter J Hoekstra, Tessa F Blanken, Anouk Schrantee","doi":"10.1007/s00787-024-02610-8","DOIUrl":"https://doi.org/10.1007/s00787-024-02610-8","url":null,"abstract":"<p><p>Stimulant medication is effective in alleviating overall symptom severity of attention-deficit/hyperactivity disorder (ADHD), yet interindividual variability in treatment response and tolerability still exists. While network analysis has identified differences in ADHD symptom relations, the impact of stimulant medication remains unexplored. Increased understanding of this association could provide valuable insights for optimizing treatment approaches for individuals with ADHD. In this study, we compared and characterized ADHD symptom networks (including 18 ADHD symptoms) between stimulant-treated (n = 348) and untreated (n = 70) individuals with ADHD and non-ADHD controls (NACs; n = 444). Moreover, we compared symptom networks between subgroups defined by their stimulant treatment trajectory (early-and-intense use, late-and-moderate use). Stimulant-treated individuals with ADHD showed stronger associations between symptoms, compared with untreated individuals with ADHD and NACs. We found no differences in symptom networks between the stimulant treatment trajectory subgroups. Prospective longitudinal studies are needed to disentangle whether the identified differences stem from treatment or pre-existing factors.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capturing complexity: cultural and demographic nuances in suicidal tendencies research among chinese students. 把握复杂性:中国学生自杀倾向研究中的文化和人口细微差别。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-09 DOI: 10.1007/s00787-024-02613-5
Mahindra Bandari, Cindy Osei, Manisha Bandari, Uzay Cagatay, Warren Chan
{"title":"Capturing complexity: cultural and demographic nuances in suicidal tendencies research among chinese students.","authors":"Mahindra Bandari, Cindy Osei, Manisha Bandari, Uzay Cagatay, Warren Chan","doi":"10.1007/s00787-024-02613-5","DOIUrl":"https://doi.org/10.1007/s00787-024-02613-5","url":null,"abstract":"","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electrophysiological indices of reward anticipation as ADHD risk and prognostic biomarkers. 作为多动症风险和预后生物标志物的奖赏预期电生理指标。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-08 DOI: 10.1007/s00787-024-02606-4
Nóra Bunford, Kristóf Ágrez, György Hámori, Júlia Koller, Attila Pulay, Zsófia Nemoda, János M Réthelyi
{"title":"Electrophysiological indices of reward anticipation as ADHD risk and prognostic biomarkers.","authors":"Nóra Bunford, Kristóf Ágrez, György Hámori, Júlia Koller, Attila Pulay, Zsófia Nemoda, János M Réthelyi","doi":"10.1007/s00787-024-02606-4","DOIUrl":"https://doi.org/10.1007/s00787-024-02606-4","url":null,"abstract":"<p><p>The attention-deficit/hyperactivity disorder (ADHD) clinical phenotype has limitations for deciphering ADHD etiology and predicting prognosis. Although relative to the clinical phenotype, intermediate phenotypes may have better explanatory and prognostic power, the extent to which ADHD intermediate phenotypes are associated with ADHD risk and prognosis is unknown. The aim of this study was to evaluate evidence for event-related potential (ERP) measures of reward anticipation as ADHD risk and prognostic biomarkers. We examined, whether (1) in a sample of adolescents (N = 304; M<sub>age</sub> = 15.78 years, SD = 1.08; 39.5% female), accounting for the effects of age, sex, ADHD severity and depression, ERPs are associated with ADHD polygenic risk scores (PRSs) (ADHD risk) and (2) in a sample of adolescents at-risk for ADHD (n = 99; M<sub>age</sub> = 15.78 years, SD = 1.08; 39.5% female), accounting for the effects of age, sex, ADHD severity, depression, and baseline outcome values, ERPs are associated, prospectively, with alcohol misuse (ADHD prognosis). In adolescents, greater ADHD PRSs were associated with lower electrophysiological anticipatory attention to motivationally relevant feedback (b = -0.115, p = .046 95%CI [-0.228; -0.002]). The predictors accounted for 5% of the variance in the outcome. In adolescents at-risk for ADHD, at 18-month follow-up, lower electrophysiological anticipatory attention to motivationally relevant feedback was associated with greater alcohol consumption (b = -7.454, p = .007, 95%CI [-12.873; -2.034]). The predictors accounted for 31% of the variance in this outcome. These findings were replicated in sensitivity analyses with behavioral performance variables added as covariates. The current findings support the hypothesis that ERP amplitudes of reward anticipation may be ADHD risk and prognostic biomarkers and suggest that intermediate phenotypes may confer advantages over the ADHD clinical phenotype in delineating etiology and predicting prognosis.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142616631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuroanatomical basis of language ability in an autism subgroup with moderate language deficits. 具有中度语言障碍的自闭症亚群语言能力的神经解剖学基础。
IF 6 2区 医学
European Child & Adolescent Psychiatry Pub Date : 2024-11-08 DOI: 10.1007/s00787-024-02605-5
Yaqiong Xiao, Ningxuan Zhang, Kaiyu Huang, Shuiqun Zhang, Jin Xin, Qingshan Huang, Aiwen Yi
{"title":"Neuroanatomical basis of language ability in an autism subgroup with moderate language deficits.","authors":"Yaqiong Xiao, Ningxuan Zhang, Kaiyu Huang, Shuiqun Zhang, Jin Xin, Qingshan Huang, Aiwen Yi","doi":"10.1007/s00787-024-02605-5","DOIUrl":"https://doi.org/10.1007/s00787-024-02605-5","url":null,"abstract":"<p><p>Children with autism spectrum disorder (ASD) are highly heterogenous in their language abilities. A number of studies have shown neural correlates of language deficits in children with ASD, but the underlying neuroanatomical foundation of early language deficits in ASD remains largely elusive. In this study, we analyzed MRI data from a cohort of Chinese children with ASD (n = 67) and typical development (TD, n = 37) aged 1.5 to 6.5 years. The ASD sample was classified into two subgroups based on the median of the language scores: ASD with moderate language deficits (ASD<sub>moderate</sub>, n = 34) and ASD with severe language deficits (ASD<sub>severe</sub>, n = 34). We tested the group differences in the brain volumes between TD and two ASD subgroups, and also examined the associations between cortical grey matter volume and language abilities in TD and ASD subgroups, separately. We observed significant group differences in grey matter and white matter volume, with post-hoc analyses specifically indicating significant differences between TD and ASD<sub>moderate</sub> subgroup. Significant correlations between grey matter volume and language scores were observed exclusively within the ASD<sub>moderate</sub> subgroup, including positive associations in the bilateral superior temporal gyrus, hippocampus, and left inferior parietal lobe, and negative correlations in the bilateral precuneus. These findings provide novel evidence for the neuroanatomical basis related to language ability in an ASD subgroup with moderate language deficits, and offer new insights into the heterogeneity of language deficits in children with ASD.</p>","PeriodicalId":11856,"journal":{"name":"European Child & Adolescent Psychiatry","volume":" ","pages":""},"PeriodicalIF":6.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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