Daniel Graf, Stefan Lerch, Ulrich Böhnke, Corinna Reichl, Michael Kaess
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引用次数: 0
摘要
在当前全球危机和紧张的精神卫生系统背景下,儿童和青少年精神病学的家庭治疗(HT)是一个日益重要的话题。我们实施了一个由多专业治疗团队提供的HT方案,并比较了27例患者(48%女性,Ø15.15±2.77岁)和48例患者(69%女性,Ø16.35±2.87岁)的长期结果,这些患者接受了常规住院治疗(I-TAU)。采用国家儿童和青少年健康结果量表(HoNOSCA[-SR])评估精神病理学,在入院、出院和出院后18-24个月采用全球功能评估(GAF)评估心理社会功能。采用混合模型分析治疗结果。结果显示,与I-TAU组相比,HT组患者随访时HoNOSCA评分显著降低(β = -4.25 [95%CI: -7.64 ~ -0.86], SE = 1.73, p = 0.014), GAF评分显著升高(β = 12.09 [95%CI: 4.48 ~ 19.70], SE = 3.88, p = 0.002)。HoNOSCA-SR评分(β = -2.46 [95%CI: -9.16 ~ 4.30], SE = 3.43, p = 0.48)和再入院率(OR = 1.23 [95%CI = 0.47 ~ 3.20], p = 0.67)无显著差异。这些结果强调了HT在改善青少年心理健康的长期功能和精神病理结果方面的潜力。HT可能是一种同样有效甚至更可持续的治疗儿童和青少年精神障碍的方法。该试验已在德国临床试验注册中心(DRKS00025424, 05/27/2021)进行预注册。
Comparison of the long-term outcome of home vs. inpatient treatment: 18-24 months follow-up of a non-randomized controlled trial.
Home Treatment (HT) in child and adolescent psychiatry is an increasingly important topic in the current context of global crises and strained mental health systems. We implemented a HT program provided by a multiprofessional treatment team and compared long-term outcomes of 27 patients (48% female, Ø15.15 ± 2.77 years) with those of 48 patients (69% female, Ø16.35 ± 2.87 years) who received inpatient treatment as usual (I-TAU). Psychopathology was assessed using the Health of the Nation Outcome Scale for Children and Adolescents (HoNOSCA[-SR]) and psychosocial functioning was assessed using the Global Assessment of Functioning (GAF) at admission, discharge, and 18-24 months after discharge. Treatment outcomes were analyzed using mixed models. The results showed that patients in the HT arm had significantly lower HoNOSCA scores at follow-up (β = -4.25 [95%CI: -7.64 to -0.86], SE = 1.73, p = 0.014) and higher GAF scores (β = 12.09 [95%CI: 4.48 to 19.70], SE = 3.88, p = 0.002) compared to those in the I-TAU arm. No significant differences were observed in HoNOSCA-SR scores (β = -2.46 [95%CI: -9.16 to 4.30], SE = 3.43, p = 0.48) and readmission rates (OR = 1.23 [95%CI = 0.47 to 3.20], p = 0.67). These results highlight the potential of HT in improving long-term functional and psychopathological outcomes in youth mental health. HT may be an equally effective and even more sustainable type of treatment for child and adolescent mental disorders. The trial was preregistered at the German Clinical Trials Register (DRKS00025424, 05/27/2021).
期刊介绍:
European Child and Adolescent Psychiatry is Europe''s only peer-reviewed journal entirely devoted to child and adolescent psychiatry. It aims to further a broad understanding of psychopathology in children and adolescents. Empirical research is its foundation, and clinical relevance is its hallmark.
European Child and Adolescent Psychiatry welcomes in particular papers covering neuropsychiatry, cognitive neuroscience, genetics, neuroimaging, pharmacology, and related fields of interest. Contributions are encouraged from all around the world.