Advanced Science最新文献_第4页

A Single-Capillary Open Microfluidic Probe for Robust and Versatile Spatial Multi-Omics Using Ambient Mass Spectrometry Imaging. 单毛细管开放微流体探针鲁棒和多功能空间多组学使用环境质谱成像。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-05 DOI: 10.1002/advs.78657

Xiangyu Zhu, Yunkai Li, Jianing Wang, Chengyi Xie, Lei Guo, Yanyan Chen, Thomas Ka-Yam Lam, Shao-Wen Shi, Kun Wang, Baoliang Chen, Zongwei Cai

{"title":"A Single-Capillary Open Microfluidic Probe for Robust and Versatile Spatial Multi-Omics Using Ambient Mass Spectrometry Imaging.","authors":"Xiangyu Zhu, Yunkai Li, Jianing Wang, Chengyi Xie, Lei Guo, Yanyan Chen, Thomas Ka-Yam Lam, Shao-Wen Shi, Kun Wang, Baoliang Chen, Zongwei Cai","doi":"10.1002/advs.78657","DOIUrl":"10.1002/advs.78657","url":null,"abstract":"High-resolution spatial mapping of tissue molecular architecture-from metabolites and lipid isomers to native proteins-remains a central challenge for ambient mass spectrometry imaging (MSI). Existing methods typically rely on multi-capillary, alignment-sensitive liquid-extraction probes, compromising robustness and compatibility with structure-resolved spatial omics. We mitigate this trade-off by introducing a monolithic, knot-shaped open microfluidic probe (Knot-probe) fabricated from a single capillary. Knot-probe achieves 40 µm scan-direction spatial resolution and acquisition throughput up to 0.16 mm s-1, yet can be fabricated in ∼30 min with standard laboratory tools and operated reliably for over one month. Without sacrificing conventional spatial lipidomics and metabolomics, Knot-probe enables structure-resolved spatial omics, delivering high-resolution imaging of phosphatidylcholine sn-positional isomers via tandem MS and, in a pneumatically-assisted variant, native MSI of proteins and proteoforms with higher throughput and enhanced sensitivity than with probes lacking pneumatic assistance. These capabilities arise from the integrated knot geometry, which ensures a stable micro-liquid junction for localized extraction with a minimized sampling footprint and efficient mass transfer, while eliminating intricate probe alignment for robust operation. Readily integrated with standard electrospray ionization MS, Knot-probe bridges conventional ambient MSI and emerging structural spatial omics, offering a broadly accessible approach across diverse biological and chemical applications.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13735432/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gd-Mediated Spin-State Modulation of Co Sites Enhances Oxygen Electrocatalysis in Zn-Air Battery. gd介导的Co位自旋态调制增强zn -空气电池中的氧电催化作用。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-05 DOI: 10.1002/advs.78659

Yijie Shen, Yu Zhu, Tianrui Zhao, Yiwen An, Xuan Wang, Meng Li, Dongmei Sun, Linda Zhang, Hao Li, Yawen Tang, Gengtao Fu

{"title":"Gd-Mediated Spin-State Modulation of Co Sites Enhances Oxygen Electrocatalysis in Zn-Air Battery.","authors":"Yijie Shen, Yu Zhu, Tianrui Zhao, Yiwen An, Xuan Wang, Meng Li, Dongmei Sun, Linda Zhang, Hao Li, Yawen Tang, Gengtao Fu","doi":"10.1002/advs.78659","DOIUrl":"10.1002/advs.78659","url":null,"abstract":"Co-based catalysts are promising alternatives to precious-metal catalysts towards oxygen reduction reaction (ORR), yet the limited electronic flexibility of Co sites constrains the adsorption and conversion of oxygen-containing intermediates. Herein, we propose a Gd-mediated spin-state modulation strategy to enhance electrocatalytic ORR performance of Co sites. The incorporation of Gd into Co sites is realized by zeolitic imidazolate framework-8, forming a Gd-modified Co─N─C catalyst (GdCo/NC). The resulting GdCo/NC exhibits a higher half-wave potential of 0.861 V in alkaline media than that of Co/NC (0.824 V) and commercial Pt/C (0.843 V). The rechargeable Zn-air battery assembled with GdCo/NC demonstrates great practical performance, delivering a high peak power density of 170.8 mW cm-2 and a large specific capacity of 733 mAh g-1, outperforming that of Pt/C + RuO2 benchmark. Theoretical calculations reveal that Gd incorporation modulates the local electronic structure of Co centers by inducing pronounced spin splitting and orbital-selective spin polarization, which shifts the dominant spin polarization from dz2 orbital to dyz orbital and lifts the degeneracy of dxz and dyz orbitals. Such spin-dependent electronic reconstruction optimizes the adsorption of oxygen-containing intermediates and shifts the rate-determining step from *O protonation to *OH desorption, thus leading to excellent ORR performance.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13735430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial Geosmin Biosynthesis is Compartmentalized Inside a Two-Component Protein Shell. 细菌土臭素的生物合成是在一个双组分蛋白外壳内划分的。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-05 DOI: 10.1002/advs.78609

Asif Fazal, Cassandra A Dutcher, Michael P Andreas, Tobias W Giessen

{"title":"Bacterial Geosmin Biosynthesis is Compartmentalized Inside a Two-Component Protein Shell.","authors":"Asif Fazal, Cassandra A Dutcher, Michael P Andreas, Tobias W Giessen","doi":"10.1002/advs.78609","DOIUrl":"10.1002/advs.78609","url":null,"abstract":"Terpenoids are ubiquitous, structurally diverse natural products found across the three domains of life. One of the most commonly observed and well-studied terpenoids is the volatile, petrichoric compound geosmin, responsible for the earthy smell of soil to which humans are receptive down to a few parts per trillion. Bioinformatic analysis of bacterial geosmin synthase (GeoA)-encoding gene clusters reveals that many are colocalized with genes encoding Family 2B encapsulin shell proteins. Here, we focus on the encapsulin-encoding geosmin gene cluster of the model myxobacterium Myxococcus xanthus and show that the two shell proteins form a two-component Family 2B encapsulin with GeoA as the internalized cargo. Structural analysis highlights that the shell contains characteristic, external cyclic adenosine monophosphate (cAMP) binding-fold domains (CBDs), and that mixed shells can adopt a previously unobserved closed two-fold pore conformation. We show that GeoA cargo loading is mediated by repeating, short cargo loading peptides (CLPs), and that GeoA encapsulation provides benefits for enzyme activity and stability. This work expands the short list of Family 2B encapsulins known to be involved in specialized metabolite biosynthesis, and provides insights into a putative mode of cargo protein regulation via pore state modulation.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13739066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149339970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Au Quantum Dots Anchored Y-MOF Enabling Directional Interfacial Charge Transfer for Synergistic Redox Photocatalysis. 金量子点锚定Y-MOF实现协同氧化还原光催化的定向界面电荷转移。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-05 DOI: 10.1002/advs.78695

Hui Yang, Dong Xu, Xue Lu, Yinbao Wu, Feng Tang, Linfu Xie, Saisai Yuan, Xiaozhi Wang, Qitao Zhang, Bin Xu

{"title":"Au Quantum Dots Anchored Y-MOF Enabling Directional Interfacial Charge Transfer for Synergistic Redox Photocatalysis.","authors":"Hui Yang, Dong Xu, Xue Lu, Yinbao Wu, Feng Tang, Linfu Xie, Saisai Yuan, Xiaozhi Wang, Qitao Zhang, Bin Xu","doi":"10.1002/advs.78695","DOIUrl":"10.1002/advs.78695","url":null,"abstract":"The synergistic photocatalytic production of hydrogen coupled with pollutant degradation offers a transformative pathway toward sustainable energy and environmental remediation. Here, a novel bifunctional photocatalyst was prepared by anchoring Au quantum dots (QDs) onto a pyrene-derived yttrium-based metal-organic framework (Au/YT) using a one-pot solvothermal approach. Notably, the optimized 2.0%Au/YT demonstrated an outstanding photocatalytic redox activity for H2 production and toxic acetaldehyde (CH3CHO) removal simultaneously under visible light irradiation, surpassed 15.94- and 19.86-times higher than that of original H4TBAPy counterpart. Comprehensive optical and electrochemical analyzes indicated that Au QDs significantly expand the light absorption range while also successfully speeding up the separation of photogenerated carriers. Meanwhile, the intrinsic multilayered structure of Y-MOFs further synergizes with the anchored Au-QD sites to establish metal-support interactions and augment charge transport dynamics, leading to a remarkable improvement in collaborative photocatalytic efficiency. Additionally, in situ XPS tests and DFT calculations substantiated a robust electronic interplay at the Au/YT interface, which effectually orchestrates directed interfacial charge migration and optimizes the adsorption/activation energy of reactant molecules. This work pioneers the development of dual-functional rare earth-based MOFs photocatalysts and furnishes fundamental insights into the rational design of synergistic redox photocatalysis systems tailored for clean solar energy production and environmental stewardship.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13735439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epigenetic Activation of ANGPTL4 Drives EBV-Negative Gastric Cancer via Neutrophil Recruitment and NET Release via Stabilizing ANXA5. ANGPTL4的表观遗传激活通过中性粒细胞募集和NET释放通过稳定ANXA5驱动ebv阴性胃癌。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-05 DOI: 10.1002/advs.78595

Dandan Li, Xinqi Li, Xiangyin Luo, Jiayi Wang, Yiwei Zha, Zeng Zhou, Yanyan Chen, Qi Wang, Lingyun Xia, Weidong Leng, Shanshan Qin

{"title":"Epigenetic Activation of ANGPTL4 Drives EBV-Negative Gastric Cancer via Neutrophil Recruitment and NET Release via Stabilizing ANXA5.","authors":"Dandan Li, Xinqi Li, Xiangyin Luo, Jiayi Wang, Yiwei Zha, Zeng Zhou, Yanyan Chen, Qi Wang, Lingyun Xia, Weidong Leng, Shanshan Qin","doi":"10.1002/advs.78595","DOIUrl":"10.1002/advs.78595","url":null,"abstract":"EBV-positive (EBVaGC) and EBV-negative (EBVnGC) gastric cancers exhibit distinct clinical outcomes, prognostic features, and immune infiltration landscapes; however, the molecular mechanisms driving these subtype differences, as well as the subtype-specific epigenetic regulation and biological functions of ANGPTL4 within the immune microenvironment, remain unclear. Here, through integrated analysis of multi-omics data, we discovered that EBV infection induces marked hypermethylation at the ANGPTL4 promoter, leading to transcriptional silencing of ANGPTL4 in EBVaGC. Conversely, hypomethylation-mediated ANGPTL4 overexpression is clinically associated with poor prognosis and distant metastasis in EBVnGC. Mechanistically, the C-terminal secreted form (cANGPTL4) promotes GC progression by enhancing proliferation, epithelial-mesenchymal transition (EMT), and neutrophil recruitment. Clinically, ANGPTL4 expression is positively correlated with neutrophil infiltration and neutrophil extracellular traps (NETs) levels in GC. Spatial transcriptomics and immunohistochemistry (IHC) analyses confirmed the spatial colocalization of ANGPTL4 with tumor-infiltrating neutrophils. cANGPTL4 mediates tumor-associated neutrophil (TAN) recruitment via the NF-κB/CXCL8 axis and directly binds and stabilizes neutrophil-derived ANXA5 to facilitate NET release, thereby driving GC progression. In conclusion, ANGPTL4 represents a potential intervention target for EBVnGC. Targeting ANGPTL4 may exert dual anti-tumor effects by directly suppressing GC proliferation, EMT, and metastasis, and by remodeling the immunosuppressive microenvironment via attenuating TANs infiltration and NET release.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13735440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Blocking Honeybee Preference for Neonicotinoids by Interfering With Dopamine Signaling. 干扰多巴胺信号阻断蜜蜂对新烟碱的偏好。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-04 DOI: 10.1002/advs.78535

Jing Li, Yuan Ge, Wangjiang Feng, David C Lyon, Pingli Dai, Yong-Jun Liu

{"title":"Blocking Honeybee Preference for Neonicotinoids by Interfering With Dopamine Signaling.","authors":"Jing Li, Yuan Ge, Wangjiang Feng, David C Lyon, Pingli Dai, Yong-Jun Liu","doi":"10.1002/advs.78535","DOIUrl":"10.1002/advs.78535","url":null,"abstract":"Honeybees (Apis mellifera) prefer nectar containing neonicotinoids despite severe exposure risk leading to colony collapse. The neural mechanisms underlying this preference behavior remain unknown, impeding the development of effective blocking strategies. Neonicotinoids act as acetylcholine receptor agonists, and dopamine is a vital neuromodulator in addictive behavior. We hypothesize that neonicotinoids could activate brain dopamine signaling in honeybees, reinforcing their feeding behavior. Here, we show that thiamethoxam-laden food is preferred over uncontaminated options, and that prolonged consumption is associated with transient, state-dependent increases in brain dopamine concentrations. Introducing the dopamine receptor antagonist, fluphenazine, reduces thiamethoxam preference. Our study first reveals a key dopamine-associated mechanism underlying neonicotinoid-induced preference behavior in honeybees and provides a potential basis for future strategies to reduce honeybee attraction to insecticide-containing food source through modulation of the preference-related dopamine pathway, thereby helping to preserve honeybee pollination services.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13736161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weak‑Solvation‑Mediated Localized High‑Concentration Electrolyte for Sodium Metal Batteries. 钠金属电池用弱溶剂化介导的局部高浓度电解液。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-04 DOI: 10.1002/advs.78680

Hongxu Qu, Huihua Li, Jingxuan Wang, Mingxing Zhang, Yang Wang, Yuhang Meng, Sailei Shao, Stefano Passerini, Huang Zhang

{"title":"Weak‑Solvation‑Mediated Localized High‑Concentration Electrolyte for Sodium Metal Batteries.","authors":"Hongxu Qu, Huihua Li, Jingxuan Wang, Mingxing Zhang, Yang Wang, Yuhang Meng, Sailei Shao, Stefano Passerini, Huang Zhang","doi":"10.1002/advs.78680","DOIUrl":"10.1002/advs.78680","url":null,"abstract":"Sodium metal batteries offer high energy density and material sustainability, yet their practical viability is severely compromised by the intrinsic instability of sodium metal anodes. Herein, we report a localized high‑concentration structure formed in a moderate‑solvating electrolyte by introducing methyl tert‑butyl ether (MTBE) as a fluorine‑free, weakly coordinating diluent in tetrahydrofuran (THF)/NaFSI electrolyte. MTBE displaces free THF molecules, promotes FSI- incorporation into the inner solvation sheath, and transforms the solvation structure from solvent‑separated ion pairs to contact ion pairs and aggregates. This diluent‑participated solvation, with its weak interaction with Na+, accelerates desolvation kinetics and forms a robust, anion‑derived inorganic‑rich interphase that suppresses parasitic reactions, dendrites, and corrosion. The optimal electrolyte enables Na||Na4Fe3(PO4)2P2O7 cells to deliver 74.3 mAh g-1 at 5.0 A g-1 and remarkable cycling stability with a high-loading cathode (12 mg cm-2) over 600 cycles. A pouch cell sustains 300 cycles with a capacity of 92.4 mAh g-1 at 0.1 A g-1. This work demonstrates a sustainable, polyfluoroalkyl substances (PFAS)‑free electrolyte design based on weak solvation engineering, offering a practical route toward stable and fast‑charging sodium metal batteries with enhanced cathode compatibility.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13736191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zr Incorporation Into Lithium Nickel Oxides: Bulk or Surface Substitution? Zr掺入锂镍氧化物：大块置换还是表面置换？

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-04 DOI: 10.1002/advs.78453

Lars Winkler, Geon-Tae Park, Liang-Yin Kuo, Martin Ihrig, Konstantin Köster, Johan E Ten Elshof, Mark Huijben, Myoung-Chan Kim, Min-Gyu Seo, Yang-Kook Sun, Payam Kaghazchi

{"title":"Zr Incorporation Into Lithium Nickel Oxides: Bulk or Surface Substitution?","authors":"Lars Winkler, Geon-Tae Park, Liang-Yin Kuo, Martin Ihrig, Konstantin Köster, Johan E Ten Elshof, Mark Huijben, Myoung-Chan Kim, Min-Gyu Seo, Yang-Kook Sun, Payam Kaghazchi","doi":"10.1002/advs.78453","DOIUrl":"10.1002/advs.78453","url":null,"abstract":"High-capacity lithium nickel oxides (LNO) are promising cathode active materials for next-generation batteries. However, their practical application is limited by poor cycling stability. Doping the LNO cathode with high-valence elements is an effective strategy to enhance structural stability. In this study, we investigate the mechanism of Zr4+ incorporation into LNO using experimental and theoretical techniques. Our findings reveal that under oxygen-rich conditions, Zr-doped LNO can be realized as a single phase, but most Zr cations localize at the surface of primary particles. In contrast, under oxygen-deficient or non-equilibrium conditions a secondary layered Li1-xNi1+xO2 phase, characterized by Ni migration into the Li layers (cation ordering), is stabilized coexisting with Zr-doped LNO. This promotes elongation of primary particles at the aggregation surface. The Zr enrichment at the microparticle surface, Zr-induced cation-ordered superstructure, and the formation of elongated grains enhance the chemical stability as well as the structural integrity at atomistic- and micro-scale of the LNO cathode, improving its cycling performance. However, only 1-3% Zr is necessary to maintain the initial capacity and enhance cyclability through surface coating and low bulk doping with Zr. With increasing Zr concentration, an electronically insulating impurity (Li2ZrO3) forms, leading to a decrease in the initial capacity.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13736196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wearable E-Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems. 用于心血管监测的可穿戴电子纺织品：材料，设备和集成系统。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-04 DOI: 10.1002/advs.77999

Bangul Khan, Mahmoud Tavakoli, Norbert Radacsi, Bee Luan Khoo

{"title":"Wearable E-Textiles for Cardiovascular Monitoring: Materials, Devices, and Integrated Systems.","authors":"Bangul Khan, Mahmoud Tavakoli, Norbert Radacsi, Bee Luan Khoo","doi":"10.1002/advs.77999","DOIUrl":"10.1002/advs.77999","url":null,"abstract":"Cardiovascular diseases remain the leading cause of morbidity and mortality worldwide, highlighting the need for continuous, non-invasive, and reliable physiological monitoring beyond conventional clinical assessments. Smart textiles have emerged as a promising platform for personalized cardiovascular healthcare by combining wearability, mechanical comfort, and seamless integration into everyday garments. This review examines recent advances in conductive materials, textile manufacturing technologies, and system-level device integration for cardiovascular sensing applications. Metallic fibers, carbon nanomaterials, and conducting polymers are evaluated for electrical conductivity, stretchability, mechanical durability, and wash stability. Furthermore, textile fabrication approaches, including weaving, knitting, embroidery, printing, and electrospinning, are analyzed for their ability to translate material properties into scalable, manufacturable sensing architectures. Recent developments in textile-integrated electrocardiography, pulse-wave, blood pressure, and hemodynamic monitoring demonstrate performance approaching clinical standards, with high signal fidelity and strong agreement with conventional medical devices. Key challenges related to long-term stability, power autonomy, signal reliability, and large-scale manufacturing are discussed alongside emerging solutions, including MXene-based electrodes, self-powered sensing systems, and edge artificial intelligence. Finally, future perspectives are outlined for developing clinically validated, scalable, and intelligent smart textile platforms that enable continuous cardiovascular monitoring and next-generation personalized healthcare.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13736708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrocatalytic Urea Synthesis From CO₂ and N₂/NO₃ ^-: Bridging Catalyst Activity, C-N Coupling Kinetics, and Industrial Applicability. CO2和N2/NO3 -电催化合成尿素：桥接催化剂活性、C-N耦合动力学和工业适用性。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-11-04 DOI: 10.1002/advs.78592

Fulin Dong, Ruihan Zhang, Huiyu Lou, Tianshi Gao, Guangjin Zhang, Menglei Yuan

{"title":"Electrocatalytic Urea Synthesis From CO2 and N2/NO3 -: Bridging Catalyst Activity, C-N Coupling Kinetics, and Industrial Applicability.","authors":"Fulin Dong, Ruihan Zhang, Huiyu Lou, Tianshi Gao, Guangjin Zhang, Menglei Yuan","doi":"10.1002/advs.78592","DOIUrl":"10.1002/advs.78592","url":null,"abstract":"Electrocatalytic urea synthesis enables the co-conversion of CO2 and N2/NO3 - under ambient conditions and offers a sustainable alternative to conventional energy-intensive processes. This review systematically summarizes the NO3 - + CO2 and N2 + CO2 systems in terms of feedstock properties, catalyst design, reaction mechanisms, performance optimization, and engineering applications. The NO3 - + CO2 system, benefiting from facile NO3 - activation and high aqueous accessibility, has achieved significant improvements in efficiency and selectivity through rate matching and side-reaction suppression, with performance approaching practical viability. The N2 + CO2 system, though more sustainable in feedstock, remains constrained by the high N≡N bond energy and low solubility, with current research focusing on N2 activation and intermediate regulation, while performance still lags considerably. The two systems differ markedly in nitrogen activation pathways and regulatory mechanisms, corresponding to distinct developmental stages and application potentials. Finally, challenges and future directions are outlined in terms of catalyst design, mechanistic studies, reactor engineering, and standardized evaluation, providing guidance for the construction of efficient systems and their scale-up applications.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13736192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149331790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0