Advanced Science最新文献_第2页

Correction to “POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation” 更正“POU2F1通过减弱PPP1R11乳酸化介导的MDR2降解促进结直肠癌细胞的化疗耐药”。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-07-30 DOI: 10.1002/advs.76815

引用次数: 0

Pressure-Tuned Superconducting Dome and Persistent Charge-Density-Wave Order in NdSeTe₂. NdSeTe2中压力调谐超导圆顶和持续电荷密度波序。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 DOI: 10.1002/advs.77597

Shuyang Wang, Chao An, Jiaqi Chen, Lili Zhang, Yonghui Zhou, Xuliang Chen, Zhaorong Yang

{"title":"Pressure-Tuned Superconducting Dome and Persistent Charge-Density-Wave Order in NdSeTe2.","authors":"Shuyang Wang, Chao An, Jiaqi Chen, Lili Zhang, Yonghui Zhou, Xuliang Chen, Zhaorong Yang","doi":"10.1002/advs.77597","DOIUrl":"https://doi.org/10.1002/advs.77597","url":null,"abstract":"In many charge-density-wave (CDW) materials, superconductivity emerges as CDW order collapses, producing a dome-shaped phase diagram commonly associated with quantum criticality or direct competition between the two orders. Here, a distinct pressure-tuned case is identified in NdSeTe2, where the superconducting dome is fully embedded within a persistent CDW state. Electrical resistivity measurements reveal a conventional superconducting dome with a maximum transition temperature of TC ≈ 1.8 K near PC ≈ 2.6 GPa, where long-range CDW signatures disappear from transport. In striking contrast, high-pressure, low-temperature Raman spectroscopy uncovers short-range CDW correlations that remain hidden to resistivity, emerge beyond PC, and persist up to ∼10.0 GPa, spanning the entire superconducting dome. Synchrotron X-ray diffraction detects no structural transition up to 32.4 GPa, indicating that the CDW evolution is electronic in origin. These results establish an unusual phase diagram in which superconductivity develops within a persistent short-range CDW background, offering new insight into pressure-tuned collective states in low-dimensional quantum materials.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e77597"},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fusing Direct and Indirect Measurements Through Multi-Fidelity Learning For Accelerated Electrocaloric Materials Discovery. 通过多保真度学习融合直接和间接测量加速发现电热材料。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 DOI: 10.1002/advs.77152

Bo Wang, Pengfei Dang, Yuan Tian, Zhengwang He, Wei Gu, Lixue Zhang, Turab Lookman, Yumei Zhou, Dezhen Xue

{"title":"Fusing Direct and Indirect Measurements Through Multi-Fidelity Learning For Accelerated Electrocaloric Materials Discovery.","authors":"Bo Wang, Pengfei Dang, Yuan Tian, Zhengwang He, Wei Gu, Lixue Zhang, Turab Lookman, Yumei Zhou, Dezhen Xue","doi":"10.1002/advs.77152","DOIUrl":"https://doi.org/10.1002/advs.77152","url":null,"abstract":"The data-driven discovery of high-performance electrocaloric (EC) materials is challenged by sparse direct measurements and systematic discrepancies between direct and indirect measurements, resulting in heterogeneous datasets with varying fidelity levels. Here, a co-kriging-based multi-fidelity learning framework is developed to integrate these data sources and construct a robust predictive model for <math><msub><mi>BaTiO</mi> <mn>3</mn></msub> </math> -based ferroelectric ceramics by explicitly modeling cross-fidelity correlation and discrepancy. Combined with a multi-objective active learning strategy, the framework enables efficient optimization of low-temperature EC strength and operational temperature span across the composition-processing space. Guided by this approach, a multi-element-doped <math><msub><mi>BaTiO</mi> <mn>3</mn></msub> </math> -based ceramic exhibiting an EC strength of <math><mrow><mn>0.06</mn> <mo>×</mo> <msup><mn>10</mn> <mrow><mo>-</mo> <mn>6</mn></mrow> </msup> </mrow> </math> <math><mrow><mi>K</mi> <mo>·</mo> <mi>m</mi></mrow> </math> /V at <math><mrow><mo>-</mo> <mn>70</mn> <msup><mspace></mspace> <mo>∘</mo></msup> <mi>C</mi></mrow> </math> together with a broad operational temperature span of 75 K is identified. Experimental characterization reveals that the enhanced performance originates from a suppressed and diffuse phase transition associated with a relaxor-like or weakly ordered state, enabling broad temperature stability together with large reversible polarization. These results demonstrate that integrating multi-fidelity learning with active learning provides an effective strategy for accelerating functional materials discovery under realistic experimental constraints.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e77152"},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RHINO: An Integrative Multi-Omics Framework Linking Circadian Physiology to Precision Medicine RHINO：将昼夜生理学与精准医学联系起来的综合多组学框架。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-07-07 DOI: 10.1002/advs.76371

Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López-Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan

{"title":"RHINO: An Integrative Multi-Omics Framework Linking Circadian Physiology to Precision Medicine","authors":"Ying Chen, Chengxuan Chen, Dishu Zhou, Panpan Liu, Roberto E. López-Valiente, Yuan Liu, Cam Mong La, Isabella Beraldo Xavier, Sean M. Hartig, Pradip Saha, Zheng Sun, Leng Han, Dongyin Guan","doi":"10.1002/advs.76371","DOIUrl":"10.1002/advs.76371","url":null,"abstract":"Circadian rhythms are involved in nearly all physiological processes, and their disruption increases disease risk. Aligning drug administration timing with the body's internal clock, known as circadian medicine, holds promise for improving treatment efficacy and safety. However, systematic strategies to identify circadian-regulated therapeutic targets remain limited. Here, we develop RHINO (RHythmic Interacting Network for multi-Omics), an integrative multi-omics framework for exploring circadian regulation across diverse genetic and disease contexts, and prioritizing druggable circadian targets. Applying RHINO reveals that human genetic variation broadly shapes rhythmic gene expression, with approximately 80% of FDA-approved drug targets exhibiting genotype-dependent rhythmicity, thereby substantially expanding the druggable target landscape for more precise circadian medicine. Circadian analyses across cancer types and diseases further identify genes that consistently lose rhythmic expression, highlighting conserved circadian vulnerabilities linked to disease progression. Integrative regulatory analyses nominate upstream transcriptional regulators, including Estrogen Receptor α, associated with rhythmic disruption. Although the circadian rhythm of estrogen signaling has been recognized for decades, we show that this rhythmicity exhibits time-of-day–dependent metabolic responses in preclinical mouse models. Together, RHINO provides a community-accessible multi-omics platform that integrates genetic variation, disease-associated circadian remodeling, and regulatory inference to advance circadian medicine (https://hanlaboratory.com/RHINO).","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"13 49","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13339356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Circuits to Symphonies: A Systems-Engineering Blueprint for Multimicrobial Synthetic Biology 从电路到交响乐：多微生物合成生物学的系统工程蓝图。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-07-31 DOI: 10.1002/advs.76981

Miguel Fernández-Niño, Ludger A. Wessjohann, José Manuel Guillamón, Daniela Burgos-Toro, Silvia Moriano-Gutiérrez, Giacomo Di Matteo, Zia-ul Islam, Rinke van van Tatenhove-Pel, Vanessa Rossetto Marcelino, Rodrigo Ledesma-Amaro

{"title":"From Circuits to Symphonies: A Systems-Engineering Blueprint for Multimicrobial Synthetic Biology","authors":"Miguel Fernández-Niño, Ludger A. Wessjohann, José Manuel Guillamón, Daniela Burgos-Toro, Silvia Moriano-Gutiérrez, Giacomo Di Matteo, Zia-ul Islam, Rinke van van Tatenhove-Pel, Vanessa Rossetto Marcelino, Rodrigo Ledesma-Amaro","doi":"10.1002/advs.76981","DOIUrl":"10.1002/advs.76981","url":null,"abstract":"Synthetic biology is expanding from single-species engineering toward the design of synthetic microbial consortia capable of distributed metabolism, coordinated behavior, and enhanced functional robustness. However, engineering frameworks derived from intracellular genetic circuits remain insufficient to capture the ecological, temporal, and spatial dynamics that govern multispecies systems. Here, a symphony-inspired systems-engineering framework is presented for multimicrobial synthetic biology, organizing consortium design across four application-dependent coordination layers: communication, temporal regulation, ecological structuring, and predictive modeling. Building on this framework, a modular engineering blueprint is proposed to guide the rational selection and integration of coordination layers according to engineering objectives, translating systems-level principles into operational strategies for the construction, stabilization, and optimization of synthetic microbial consortia. The manuscript integrates advances in interspecies signaling, oscillatory control, synthetic ecology, hybrid modeling, and real-time monitoring while addressing constraints including metabolite transport, population drift, parameter uncertainty, and process-scale implementation. The proposed framework is modular rather than prescriptive, allowing different coordination layers to be deployed according to application requirements and environmental complexity. By repositioning multimicrobial engineering as a problem of coordinated systems design rather than isolated genetic control, this Perspective provides a structured foundation for the development of synthetic microbial communities across industrial, environmental, and therapeutic applications.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"13 49","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13427237/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics 面向耐用机械耦合柔性电子的表面与界面工程。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-08-06 DOI: 10.1002/advs.76797

Qian Wang, Fangfang Dai, Wei Wu

{"title":"Surface and Interfacial Engineering toward Durable Mechanically Coupled Flexible Electronics","authors":"Qian Wang, Fangfang Dai, Wei Wu","doi":"10.1002/advs.76797","DOIUrl":"10.1002/advs.76797","url":null,"abstract":"Mechanically coupled flexible electronics enable real-time, conformal monitoring of diverse mechanical signals. However, their operation in dynamic and complex environments places stringent demands on surface and interfacial reliability. Insufficient interfacial functionalization, unstable contact, as well as mechanical and electrical mismatch have emerged as key factors limiting device durability, signal fidelity, and practical deployment. This review summarizes the fundamental surface and interfacial challenges in mechanically coupled flexible electronics from the perspective of surface and interfacial physics, including contact instability, interfacial failure, stress concentration, and environmental degradation. To address these challenges, various material systems designed to enhance surface and interfacial performance are systematically reviewed, focusing on surface chemical modification, interfacial chemical engineering, as well as processing- and manufacturing-enabled physical reinforcement approaches. In addition to isolated chemical or physical methods, multiscale surface and interface architectures are further engineered through bioinspired interfaces, mechanical interlocking, adhesive interlayers, buffering layers, percolating interpenetrating networks, and homogeneous structural design. The resulting improvements in reliability and functional stability are illustrated through representative applications across multiple operating scenarios. Finally, current challenges and future directions are outlined in terms of standardization, environmental robustness, manufacturing repeatability, and large-scale implementation.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"13 49","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13445334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148676285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metal Battery Anode: Rich in Electrons, Rich in Problems: A Critical Review from Industrial Perspectives 金属电池负极：电子多，问题多：工业视角下的批判性评述。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-07-30 DOI: 10.1002/advs.76682

Jian Pan, Chan Shu, Oscar Tutusaus, Rana Mohtadi

{"title":"Metal Battery Anode: Rich in Electrons, Rich in Problems: A Critical Review from Industrial Perspectives","authors":"Jian Pan, Chan Shu, Oscar Tutusaus, Rana Mohtadi","doi":"10.1002/advs.76682","DOIUrl":"10.1002/advs.76682","url":null,"abstract":"Metal-anode batteries promise energy densities beyond conventional Li-ion. However, despite decades of study and earlier discontinued commercialization efforts, they still lag Li-ion in efficiency, cycle life, and safety, leaving practical adoption uncertain. Key challenges stem from the metals’ inherent reactivity, incomplete understanding of interphase formation and evolution, and nonstandard testing and reporting that can mask true failure modes and misses to present performance relevant to practical use. Encouragingly, progress in electrolyte development and understanding of interphases over the past decade has uncovered more shared behavior across different metals than previously assumed, alongside important metal-specific nuances. Thorough integration of these insights presents significant opportunities to deepen our knowledge and steer the field toward promising avenues for future advancements. This review unifies guiding principles for reactive monovalent (Li, Na) and multivalent (Mg, Ca) metal anodes across liquid and solid-state electrolyte designs, summarizes major advances and barriers, and flags frequent pitfalls to guide the research community.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"13 49","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13423496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148628908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota-Associated Kynurenine Accumulation and Macrophage Remodeling. 慢性应激通过诱导微生物群相关犬尿氨酸积累和巨噬细胞重塑促进胃癌转移。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 DOI: 10.1002/advs.77612

Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang

{"title":"Chronic Stress Promotes Gastric Cancer Metastasis by Inducing Microbiota-Associated Kynurenine Accumulation and Macrophage Remodeling.","authors":"Sicheng Zhao, Zhiyuan Song, Jingcheng Zhang, Jiaheng Lou, Shuo Zhang, Boqiang Liu, Yunhai Wei, Fengmei Qiu, Tao Jiang, Guangji Zhang","doi":"10.1002/advs.77612","DOIUrl":"https://doi.org/10.1002/advs.77612","url":null,"abstract":"Chronic stress frequently occurs in patients with cancer, yet how stress is translated into pro-metastatic programs remains unclear. Here, using chronic restraint stress (CRS) in male mice, we show that stress increases metastatic burden and reduces survival in lung metastasis and peritoneal dissemination models, while also increasing overall tumor burden in an orthotopic gastric cancer model. Single-cell transcriptomics of lung metastases reveals stress-associated remodeling of tumor-associated macrophages toward immunosuppressive states, while macrophage depletion attenuates stress-enhanced metastasis. Stress also reshapes the gut microbiota and enriches Lactobacillus reuteri, and microbiota transfer, antibiotic treatment, co-housing, and bacterial gavage experiments support a microbiota-dependent contribution to metastatic progression. Metabolomic analyses identify kynurenine as a stress- and L. reuteri-associated tryptophan metabolite that promotes macrophage-dependent dissemination, whereas tryptophan deficiency blunts stress- and L. reuteri-enhanced metastasis. Mechanistically, our data support a role for TNFR2-C/EBPβ signaling in Kyn-induced immunosuppressive macrophage remodeling. In clinical gastric cancer cohorts, higher depressive symptom burden is associated with shorter disease-free survival, Lactobacillus enrichment, elevated plasma Kyn/Trp ratio, and altered macrophage phenotypes. Together, these findings define a stress-microbiota-tryptophan metabolism-macrophage axis that links chronic stress to gastric cancer metastasis in male mouse models and clinical samples.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e77612"},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Redefining the Minimal Editable Unit of Supramolecular Synthons: A 1→2 Lattice-Editing Strategy in Ternary Multicomponent Crystals. 重新定义超分子合成子的最小可编辑单元：三元多组分晶体中的1→2晶格编辑策略。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 DOI: 10.1002/advs.77573

Zheng Lin, Honglei Xia, Min Li, Ruihui Wang, Ying Wang, Xiaoyu Feng, Mingjing Tang, Yuan Zhang, Qinghua Zhang

{"title":"Redefining the Minimal Editable Unit of Supramolecular Synthons: A 1→2 Lattice-Editing Strategy in Ternary Multicomponent Crystals.","authors":"Zheng Lin, Honglei Xia, Min Li, Ruihui Wang, Ying Wang, Xiaoyu Feng, Mingjing Tang, Yuan Zhang, Qinghua Zhang","doi":"10.1002/advs.77573","DOIUrl":"https://doi.org/10.1002/advs.77573","url":null,"abstract":"Conventional multicomponent crystal engineering is largely restricted to one-to-one component substitution, which often provides limited tunability or disrupts the parent lattice structure. Inspired by skeletal editing in molecular chemistry, we herein establish a lattice-editing strategy for supramolecular crystals. This work extends the conventional understanding of the minimal editable structural unit in supramolecular crystals from individual components to local supramolecular structural units, thereby moving beyond strict numerical equivalence and enabling non-stoichiometric component substitution while preserving the original interaction topology. As a proof of concept, a 1→2 component substitution was achieved in the ternary ionic crystal ethylenediamine diperchlorate hemihydrate (EP·0.5H2O) by replacing the [H2eda]2+-H2O composite unit with [H2pda]2+. The resulting anhydrous energetic crystal PEP fully retains the parent crystal framework, space group, cell parameters, and hydrogen-bonding network. PEP exhibits a high density of 1.85 g cm- 3, a phase-transition temperature increased by approximately 90°C, and a 127% enhancement in formation enthalpy. In solid propellant formulations, PEP delivers higher specific impulses than AP and ADN while simultaneously improving thermal stability, environmental stability, and mechanical safety. This work demonstrates precise lattice editing in multicomponent crystals and provides a general strategy for the rational design of high-performance functional crystalline materials.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e77573"},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148885770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to “4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways” 更正“磁性增强骨痂组合体植入物的4D生物制造通过激活机械敏感途径实现快速软骨内成骨”。

IF 14.1 1区材料科学

Advanced Science Pub Date : 2026-09-03 Epub Date: 2026-08-10 DOI: 10.1002/advs.77066

{"title":"Correction to “4D Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways”","authors":"","doi":"10.1002/advs.77066","DOIUrl":"10.1002/advs.77066","url":null,"abstract":"K. Ioannidis, A. Dimopoulos, I. Decoene, el al., 4D “Biofabrication of Magnetically Augmented Callus Assembloid Implants Enables Rapid Endochondral Ossification via Activation of Mechanosensitive Pathways,” Advanced Science 12, no. 15 (2025): 2413680, https://doi.org/10.1002/advs.202413680.In the originally published article, pixel duplication was identified in the zoomed histological panel of the control spleen in Figure 8F. Following review of the original materials and clarification provided to the journal, the duplication was determined to have resulted from a microscope tile-stitching artifact during mosaic image acquisition. To correct this issue and to ensure consistency across Figure 8F, the affected stitched/mosaic images were replaced with newly acquired single-field images using identical imaging settings and post-image processing conditions. Where no artifact or inconsistency was present, the corresponding image was retained. The corrected figure panel does not affect the interpretation of the data, the results, or the conclusions of the article. For transparency, both the originally published figure and the corrected figure are provided below.Revised Figure panel 8F:Original Figure panel 8F:The authors apologize for this error and for any inconvenience it may have caused.","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":"13 49","pages":""},"PeriodicalIF":14.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13456065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0