Environmental Toxicology and Chemistry最新文献

{"title":"Correction to: Acetylcholinesterase activity and hematological parameters in individuals exposed to pesticides in a Brazilian state: a cross-sectional study.","authors":"","doi":"10.1093/etojnl/vgaf115","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf115","url":null,"abstract":"","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ecotoxicological effects of crude oil on Danio rerio early life stages: a molecular, morphological and behavioral approach focused on swim bladder development.","authors":"Célio F Mariz, Maria Karolaine de Melo Alves, Jason T Magnuson, Italo Braga Castro, Félix Augusto Silva de Andrade, Eliete Zanardi-Lamardo, Igor Dias Medeiros, Paulo S M Carvalho","doi":"10.1093/etojnl/vgaf184","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf184","url":null,"abstract":"<p><p>Proper development and inflation of the swim bladder is essential for swimming and foraging behavior in fish. To characterize the effects of the Brazilian oil spill that occurred between 2019 and 2020 to early life stage fish, the expression of genes involved in swim bladder development were targeted, with biochemical assays, morphology, and behavior assessed. The swim bladder was focused on due to recent findings of being a target of polycyclic aromatic hydrocarbons (PAHs) present in oil. Zebrafish (Danio rerio) were exposed to oil water accommodated fractions (WAFs) at concentrations measured following the spill, 1.12 to 71.8 total PAHs (μg-ΣPAHt L-1). Larvae exposed to 4.49 and 17.9 μg-ΣPAHt L-1 had a downregulation in the expression of swim bladder development genes, hb9, sox2, has2, and elovl1a, at 48 hours post fertilization (hpf). Downregulation in these genes was associated with a high frequency of uninflated swim bladders at 96 and 168 hpf, with uninflated swim bladders detected in 100% of 96 to 168 hpf larvae exposed to 35.9 and 71.8 μg-ΣPAHt L-1. SOD and CAT levels were inhibited in larvae exposed to 1.12 and 2.24 μg-ΣPAHt L-1, respectively. There was an increase in GST and GSH levels in exposed larvae. Average swimming speed and distance were reduced in larvae exposed to 1.12 μg-ΣPAHt L-1. This suggests that complex mixtures of PAHs from crude oil can inhibit the transcription of genes involved in swim bladder tissue development and proper swim-up behavior, which may have implications for the viability and success of developing larvae, impacting recruitment.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between polycyclic aromatic hydrocarbons measured in dust collected inside cars and from ambient air.","authors":"Ivana Jakovljević, Tajana Horvat, Gordana Pehnec, Nikolina Račić, Marija Dvoršćak, Karla Jagić, Darija Klinčić","doi":"10.1093/etojnl/vgaf183","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf183","url":null,"abstract":"<p><p>Polycyclic aromatic hydrocarbons (PAH) are organic compounds with a high capacity for bioaccumulation and carcinogenic and mutagenic effects on human health. They can exist in both outdoor and indoor air. Indoors, except in the air, they can be bound to dust particles, and human intake occurs not only by inhalation but also by ingestion and dermal absorption of dust. Therefore, dust is an important source of human exposure to indoor carcinogenic contaminants. The aim of this research was to determine the contribution of individual PAHs in the total amounts of PAHs (ΣPAH) in dust collected inside cars and compare those concentrations with PAH concentrations and profiles in ambient air. Data on PAH concentrations in dust from the interior of 22 cars with diesel or gasoline engines was compared with the ambient concentration of PAHs bound to the PM10 particle fraction. The total concentration of 11 PAHs (Σ11PAH) in dust ranged from 0.39 µg g-1 to 12.1 µg g-1. Spearman correlation analysis revealed significant positive correlations (p < 0.05) between benzo(a)anthracene (BaA), chrysene (Chry), benzo(k)fluoranthene (BkF), and dibenzo(ah)anthracene (DahA) concentration in dust and ambient air. These PAHs are specific to diesel and gasoline combustion and originate from vehicle exhaust. The highest contribution in dust samples came from pyrene (Pyr) (26%), fluoranthene (Flu) (18%), and benzo(ghi)perylene (BghiP) (14%), while in ambient air samples, the highest contribution was from benzo(b)fluoranthene (BbF) (16%), BghiP (13%) and indeno(1,2,3-cd)pyrene (IP) (15%). The contribution of benzo(a)pyrene (BaP) in total PAHs was 6% and 10% in dust and ambient air, respectively, while for other PAHs below 5% in dust samples and below 10% in particles. This study has shown that passengers in cars may be exposed to elevated levels of PAHs, but that the contribution of the most toxic PAHs (BaP and DahA) in car dust is lower than that of other PAHs.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144663883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human pharmaceuticals surface water pollution across urban gradients in the Buenos Aires Metropolitan Region, Argentina.","authors":"Daniela E Perez, Macarena Rojo, Diego S Cristos, Pedro Carriquiriborde","doi":"10.1093/etojnl/vgaf181","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf181","url":null,"abstract":"<p><p>Human active pharmaceutical ingredients (HAPIs) are micropollutants of emerging concern for aquatic ecosystems. Adequate access to health systems combined with poor sewerage connectivity and inadequate wastewater treatment plants has placed developing countries among the most vulnerable scenarios regarding HAPIs water pollution. However, field data to better understand this phenomenon is still insufficient for large metropolises of South America. This study aimed to evaluate, in two contrasting seasons of the year, the occurrence of 16 highly prescribed HAPIs in 26 sites distributed along urban gradients of 7 watersheds of the Rio de la Plata estuary southern plain within the Buenos Aires Metropolitan Region. Owing to their average annual concentrations and frequencies, acetaminophen, ibuprofen, carbamazepine, atenolol, enalapril, metformin, and sildenafil were the dominant HAPIs. Total HAPIs concentrations and numbers significantly increased as the watercourses ran into more intensely populated areas. Sampling sites within urban conglomerates receiving WWTP discharges displayed higher HAPIs concentrations and numbers, demonstrating the inefficacy of current plants in eliminating these substances. Sampling sites within urban conglomerates without official discharges also showed high HAPIs concentrations and numbers, pointing out \"straight-piping\" and septic tank leaking as significant pollution sources. Detecting some HAPIs in rural sites would indicate that other minor sources (e.g., veterinary uses or atmospheric deposition) are also contributing. Shifts in HAPIs frequencies and concentrations around the overall medians were a better indicator of seasonal variations than the absolute values affected by hydrological conditions. This study enhances understanding of the relationship between urbanization and HAPIs surface water pollution in a major metropolitan area of South America, offering valuable data for future HAPIs aquatic ecological risk assessments in the region.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence and Exposure Assessment of Antibiotics, Parabens and Potentially Toxic Elements in Groundwater Sources from Two Rural Communities in Nigeria.","authors":"Oluwakemi A Akintobi, Adesola O Adedejia, Aemere Ogunlaja, Olusola A Ladokun, Olumuyiwa O Ogunlaja","doi":"10.1093/etojnl/vgaf179","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf179","url":null,"abstract":"<p><p>The presence of emerging organic contaminants (EOCs) and Potentially Toxic Elements (PTEs) in groundwater is a global concern. In Nigeria, however, monitoring and risk assessment data for EOCs such as Methylparaben (MeP), Ethylparaben (EtP), Propylparaben (PrP), Butylparaben (BuP), and antibiotics like ampicillin (AMP), chloramphenicol (CLP), ciprofloxacin (CIP), and metronidazole (MET) are scarce, especially in rural areas. This study quantified EOCs and metals in groundwater from two rural Nigerian communities using HPLC-UV and ICP-OES, with validation through recovery (99.6-101%) and linearity (R2 > 0.999). Health risks were assessed via Target Hazard Quotient (THQ), Target Carcinogenic Risk (TCR), and risk quotient (RQH). The groundwater samples followed the decreasing order: Ca > Mg > Na > K > Co > Al > Fe > Cr > Mn > Zn > Cd > Ni > Pb > B > Cu > Se for metals and MET > CIP > BuP > MeP > PrP > EtP for EOCs. Groundwater EOC concentrations were as high as 7846 (MET), 1137 (CIP), 342 (MeP), 295 (EtP), 299 (PrP), and 400 μg L - 1 (BuP) while Fe, Zn, Al, Cr, Ni, and Pb in all groundwater samples investigated were higher than the permissible limit recommended by WHO. The human risk assessment revealed both non-carcinogenic and carcinogenic hazards from Cd, Cr, Ni, and Pb, with Cr contributing ∼90% of the cumulative THQ and TCR. Additionally, CIP exhibited high RQH (>1) across all age groups, ranging from 1.142 to 49.174. Findings from this study indicate that groundwater consumption in these communities poses significant health risks.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from Modeling the Fate of and Exposure to Persistent and Mobile Organic Chemicals using the Refined PROTEX Model.","authors":"Zhizhen Zhang, Shenghong Wang, Li Li","doi":"10.1093/etojnl/vgaf182","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf182","url":null,"abstract":"<p><p>Persistent and mobile (PM) organic chemicals have been recognized as a threat to aquatic environments and drinking water quality due to their potential to infiltrate natural barriers and contaminate various sources of drinking water. Here, we refine a multimedia mass-balance model named PROduction-To-EXposure (PROTEX) to support evaluating the environmental fate of and human exposure to PM organic chemicals in different sources of drinking water. By examining a case study chemical, perfluorooctanoic acid (PFOA), we demonstrate that the multimedia transport and distribution of PM organic chemicals in a region is influenced by both the mode of emission (ie, the environmental medium/media into which a chemical is initially released) and the source of drinking water (ie, the water medium from which it is extracted). As our modeling results indicate, in humid regions, regionally released PFOA predominantly accumulates in estuarine water, potentially reaching open seas and oceans. In contrast, in arid regions, a remarkable portion of regionally released PFOA may concentrate in deep groundwater. Compared to other scenarios, contamination by PM organic chemicals is likely to be significantly less reversible when these substances are released into deep groundwater, or when drinking water is sourced from deep groundwater. In these cases, contamination may not reach a steady state within a century-scale timeframe, and dynamic modeling informed by temporal emission trends is appropriate for assessment. Our work provides a computational tool for evaluating the large numbers of chemicals on the market for their potential to impact drinking water safety. It also underscores the need to consider the mode of emission and the source of drinking water to achieve fit-for-purpose assessments of PM organic chemicals.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary kinetics of a PFAS mixture in the American toad (Anaxyrus americanus); laboratory insights into trophic transfer of PFAS.","authors":"Andrew G East, Mike Simini, Emily E Stricklin, Guilherme R Lotufo, Jennifer L Guelfo, Zhao Yang, Travis Gallo, Michael J Quinn, Roman G Kuperman","doi":"10.1093/etojnl/vgaf180","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf180","url":null,"abstract":"<p><p>Per- and polyfluoroalkyl substances (PFAS) are ubiquitous in environmental media and are a concern for food web-driven exposure to ecological receptors. Terrestrial life stage amphibians concurrently represent taxa that have high potential for exposure but are generally data-poor in comparison to their aquatic life stages. Adult American toads (Anaxyrus americanus) likely have high dermal exposure to soil and eat terrestrial organisms that are likely to accumulate chemicals from soil. To better understand the relationship between dietary PFAS and toads in a trophic transfer context, toads were fed earthworms (Eisenia andrei) exposed to PFAS-spiked soil for 28 days and then were fed clean earthworms for 28 days-a 28-day uptake phase and 28-day elimination phase. Toads' blood, liver, and remaining tissues were sampled weekly. Concentrations of PFAS were quantified in soil, earthworm diet, and toad tissues. Toxicokinetics of PFAS in toad livers, remainder, and estimated whole animal were evaluated using methods of OECD TG#305, a nonlinear regression approach, and a physiologically-based method. Definitive models were selected via a leave-one-out cross validation method and model parameters were used to determine kinetic trophic transfer coefficients (TTCs). Our TTC approach indicates PFOS, PFUdA, and PFDA are likely to magnify and 8:2 FTS and PFHpS are likely to transfer or dilute in the worm-toad transition. Most PFAS have similar uptake rates, but elimination rates are clustered, suggesting that kinetics are driven by elimination mechanisms. These laboratory data use field-representative exposure approaches and provide inference about internal kinetics of individual PFAS as well as the potential for trophic transfer from soil invertebrates to terrestrial life stage amphibian predators.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fate and effects to the benthic community of a copper treatment to eradicate invasive mussels in a large western river, USA.","authors":"Austin K Baldwin, Erin M Murray, Lauren M Zinsser, Tyler V King, Scott D Ducar, India Southern, Theresa A Thom, Christopher A Mebane","doi":"10.1093/etojnl/vgaf119","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf119","url":null,"abstract":"<p><p>Copper-based chemical treatments are commonly used to eradicate invasive mussels in small ponds and lakes, but their use in large rivers has been limited. In 2023, in response to a detection of invasive quagga mussels, a 10-km reach of the Snake River (Idaho, USA), was treated with an unprecedented 19,300 kg of chelated copper molluscicide to a target concentration of 1,000 µg/L for 10 days. We assessed the transport and fate of the copper and its exposure and effects on the nontarget benthic community downstream. Water samples were collected at seven locations throughout the treatment period, and sediment, periphyton, and benthic macroinvertebrates were collected pre- and posttreatment. Nearly half of the original mass of copper was removed from the water column via sedimentation, sorption to algae, or biological uptake within the 10-km treatment reach and the first 15 km downstream. Even so, dissolved copper concentrations exceeded the acute toxicity threshold at least as far as 28 km downstream for more than 2 weeks. Sediment copper increased by up to 8.3-fold, exceeding the consensus-based sediment quality threshold effect concentration at several sites. Effects on benthic macroinvertebrates varied by taxa. From 0-28 km downstream, invertebrate abundances decreased 52%-94%, with gastropods among the most affected. Of the unique taxa present at these sites pretreatment, 52%-64% were not found posttreatment but were replaced by other taxa, indicating a reorganization of the base of the food web. Additionally, from 0-15 km downstream, the percentage of individuals from tolerant taxa increased two to15-fold. Findings from this study can help watershed managers plan future invasive mussel responses while protecting culturally, economically, and ecologically important nontarget species in large rivers.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144636580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Reliable Pre-processing Protocol for Fluorescent Micro- and Nanoplastic Analysis in Human Placental Tissue.","authors":"Laura M Zoutendijk, Zenzi Matla, Hanna M Dusza, Barbara M Scholz-Böttcher, Bert M Weckhuysen, Laurens D B Mandemaker, Florian Meirer","doi":"10.1093/etojnl/vgaf177","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf177","url":null,"abstract":"<p><p>Concerns are arising about potential health risks of micro- and nanoplastics (MNPs) to human life, as their presence has been reported in human blood, stool, liver, lung tissue, breast milk, and placenta. However, little is known about particle numbers and morphology, which is essential information for developing reliable risk assessment. Therefore, such characterization of MNPs in human tissue is an important yet difficult task, which involves sample digestion as an essential step in the pretreatment of organic matrices. Successful digestion enables accurate characterization of MNPs using micro-spectroscopy. In this study, eight different enzymes or enzyme mixtures commonly used in digestion protocols were tested in four different buffers, to select the best combinations of enzymes and buffers for the preprocessing of human placental tissue for MNP (spectro-)microscopic analysis. Placenta tissue was spiked with fluorescent 200 nm, 500 nm, 1 μm, and 10 μm polystyrene MNPs to analyze morphological stability throughout the digestion and to determine recovery rates (RRs). For the optimal protocol, RRs of 98% ±6 (200 nm), 148% ±8 (500 nm), 147% ±8 (1 μm) and 81% ±8 (10 μm) were determined using confocal fluorescence microscopy (CFM). We explain values >100% by dye leaching and hypothesize that the leached dye can bind to organic residue from tissue with a similar size as the FPS particles, causing false positives when counting MNPs. Morphological changes were not observed for the final digestion protocol both with CFM and scanning electron microscopy. Hence, we demonstrate an optimized enzymatic digestion protocol to digest (placental) tissue and report on the accuracy of the characterization of model MNPs using micro-spectroscopy, which will enable further research with an emphasis on sub-micron (<1µm) sized plastic particles.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144612069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reduction of the bioavailable PFAS fraction in sediments using 3D printable polymer-zeolite clay composites.","authors":"Paige M Krupa, Guilherme R Lotufo, Alan Kennedy, Mark Ballentine, Charles A Ponge, David R Corbin, Mark B Shiflett, Ashley N Kimble","doi":"10.1093/etojnl/vgaf176","DOIUrl":"https://doi.org/10.1093/etojnl/vgaf176","url":null,"abstract":"<p><p>As per- and polyfluoroalkyl substances (PFAS) pose a global environmental threat, effective and practical methods for reducing PFAS risk are crucial. To test the effectiveness of a novel treatment for immobilizing PFAS in sediment, 3D-printed (3DP) structures containing zeolite known to adsorb PFAS were inserted into a field-collected sediment (∑PFAS 140 ng/g dw) and a spiked sediment (∑PFAS 38,000 ng/g dw) for 14 days concurrently with estuarine amphipods (Leptocheirus plumulosus) to test efficiency in reducing PFAS concentrations in sediment, sediment porewater, overlying water, and bioaccumulation in tissue. Free zeolite powder and 3DP-clay structures were also tested to investigate effects of zeolite and the 3DP structures separately. Both zeolite treatments proved effective in reducing PFAS, with ∑PFAS reductions for the 3DP zeolite treatments up to 80-95% in sediment and water, and >99% in the porewater and overlying water of the free zeolite powder treatments. By reducing PFAS from the sediment and water, the 3DP zeolite also decreased PFAS bioaccumulation into the amphipods, with a 34% and 85% reduction of ∑PFAS in amphipod tissue from the field and spiked treatments, respectively. While both the 3DP and free zeolite powder treatments reduced PFAS from the sediment and water, exposure to free zeolite powder in sediment resulted in complete amphipod mortality whereas the 3DP zeolite did not significantly impact survival. As 3DP zeolite structures were successful in reducing multiple PFAS analytes from sediment, they represent a promising option for both laboratory toxicity and bioavailability reduction studies and further research and development on scalability and effectiveness in a field setting to reduce PFAS mobility and risk.</p>","PeriodicalId":11793,"journal":{"name":"Environmental Toxicology and Chemistry","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144599677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}