European Journal of Clinical Microbiology & Infectious Diseases最新文献

{"title":"Resurgence and seasonal patterns of RSV-B during the COVID-19 era: an 18-year retrospective hospital-based study.","authors":"Jeong Su Han, Hyeong Ho Kim, Jae-Sik Jeon, Jae Kyung Kim","doi":"10.1007/s10096-025-05178-6","DOIUrl":"10.1007/s10096-025-05178-6","url":null,"abstract":"<p><p>Respiratory syncytial virus (RSV) is a leading cause of severe respiratory infections, particularly in infants, older adults, and immunocompromised individuals. In this study, we aimed to characterize the epidemiology of RSV subtype B (RSV-B), which remains relatively understudied compared with subtype A despite its clinical significance. We conducted a retrospective analysis of laboratory-confirmed RSV-B infections over 18 years (2007-2024) at a tertiary hospital in South Korea. The dataset included 23,284 cases analyzed for age distribution, seasonality, sex differences, and the impact of the coronavirus disease 2019 (COVID-19) pandemic. The highest positivity rate was observed in infants under 1 year (12.7%, p < 0.001), followed by ages 1-19 years (6.9%). RSV-B incidence peaked in winter (11.9%) and autumn (8.7%), with significant seasonal variation (p < 0.001). No statistically significant sex-based difference was observed (male: 6.1%, female: 6.7%; p = 0.102). Positivity rates declined markedly during the COVID-19 pandemic (2019-2022), likely due to non-pharmaceutical interventions. These findings clarify RSV-B's distinct epidemiology and underscore the need for subtype-specific surveillance, targeted vaccination, and adaptable public health strategies. This study provides evidence to improve outbreak prediction, identify high-risk groups, and optimize clinical and preventive responses to RSV-B.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2085-2092"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of relevant pathogens and contaminants in blood cultures after implementation of single-sampling strategy and initial specimen diversion.","authors":"Karl Oldberg, Fredrik Kahn, Magnus Rasmussen, John Walles","doi":"10.1007/s10096-025-05196-4","DOIUrl":"10.1007/s10096-025-05196-4","url":null,"abstract":"","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2275-2282"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic yield of Xpert MTB/RIF, Xpert MTB/RIF Ultra, and Truenat MTB assays on non-pulmonary samples from suspected cases of extra-pulmonary tuberculosis (EPTB).","authors":"Anvita Gupta Malhotra, Leena Lokhande, Abhijit Pakhare, Payal Soni, Satya Prakash Vishwakarma, Anand Kumar Maurya, Jitendra Singh, Sarman Singh","doi":"10.1007/s10096-025-05177-7","DOIUrl":"10.1007/s10096-025-05177-7","url":null,"abstract":"<p><strong>Background: </strong>Extrapulmonary tuberculosis (EPTB) poses a diagnostic challenge due to its paucibacillary nature and low diagnostic yield of traditional methods. Molecular diagnostic tools like Xpert MTB/RIF, Xpert MTB/RIF Ultra, and Truenat MTB offer promising alternatives for the rapid and higher detection rates for pulmonary TB samples. However, the yield of these newly introduced molecular tests on extra-pulmonary samples requires country-specific evaluation and comparative analysis.</p><p><strong>Methodology: </strong>This study evaluated the diagnostic performance of Xpert MTB/RIF, Xpert MTB/RIF Ultra, and Truenat MTB assays in detecting EPTB on 211 clinical specimens collected at a tertiary care centre of central India. The assays' sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPP) were compared against a composite reference standard.</p><p><strong>Results: </strong>Xpert MTB/RIF Ultra exhibited the highest sensitivity (50%) for EPTB detection, outperforming the standard GeneXpert MTB/RIF (29.4%) and Truenat MTB (35.3%), with comparable specificity across all three assays. Among the specimen types, pus samples demonstrated the highest (value) diagnostic yield. These findings highlight the superior diagnostic capabilities of Xpert MTB/RIF Ultra, particularly in paucibacillary cases.</p><p><strong>Conclusion: </strong>Xpert Ultra demonstrates superior sensitivity for EPTB detection compared to Xpert MTB/RIF and Truenat MTB, making it a promising tool to enhance diagnostic accuracy in paucibacillary TB. Its adoption as a standard diagnostic method could significantly improve EPTB management. These findings advocate for integrating advanced molecular diagnostics into routine tuberculosis workflows to reduce diagnostic delays and improve patient outcomes.</p><p><strong>Clinical trail number: </strong>Not applicable.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2093-2103"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial activity of lefamulin against pathogens most commonly causing community-acquired pneumonia: results from the China antimicrobial surveillance network in 2020-2022.","authors":"Li Ding, Siquan Shen, Renru Han, Dandan Yin, Yang Yang, Shi Wu, Demei Zhu, Yan Guo, Fupin Hu","doi":"10.1007/s10096-025-05175-9","DOIUrl":"10.1007/s10096-025-05175-9","url":null,"abstract":"<p><strong>Objectives: </strong>Lefamulin is a novel pleuromutilin antibiotic used for the treatment of community-acquired pneumonia (CAP). This study aimed to evaluate the in vitro antimicrobial activity of lefamulin against clinical isolates obtained from China.</p><p><strong>Methods: </strong>1,052 non-duplicate isolates included the following isolates: Streptococcus pneumoniae (n = 529), Staphylococcus aureus (n = 306), Haemophilus influenzae (n = 121), Moraxella catarrhalis (n = 81), and Mycoplasma pneumoniae (n = 15), were collected from 70 hospitals participating in the China Antimicrobial Surveillance Network (CHINET) between October 1, 2020, and November 30, 2022. Minimum inhibitory concentrations were determined using the broth microdilution method in accordance with the standards set by the Clinical and Laboratory Standards Institute.</p><p><strong>Results: </strong>In vitro, S. pneumoniae exhibited 100% sensitivity to lefamulin, with MIC₉₀ values of 0.125 µg/mL for penicillin-susceptible strains, 0.25 µg/mL for penicillin-intermediate strains, and 0.125 µg/mL for penicillin-resistant strains. Lefamulin remained effective against S. pneumoniae strains resistant to penicillin, erythromycin, and azithromycin. The susceptibility rate of S. aureus to lefamulin was 97.7%, with methicillin-sensitive S. aureus showing 98.4% sensitivity and methicillin-resistant S. aureus showing 96.6% sensitivity. Both strains had MIC₉₀ values of 0.125 µg/mL. H. influenzae and M. catarrhalis demonstrated 100% sensitivity to lefamulin. The MIC of lefamulin against M. pneumoniae was ≤ 0.03 µg/mL.</p><p><strong>Conclusions: </strong>Lefamulin exhibited potent in vitro activity against prevalent and drug-resistant pathogens associated with CAP in China.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2067-2075"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144157431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the prevalence of Helicobacter pylori CagA and VacA virulence markers in Moroccan children and adolescents.","authors":"Fatima Zahra Kheir, Aicha Baalala, Omar Abidi, Abdelhak Abkari, Ghizlane Bounder, Dalal Ben Sabbahia, Meriem Atrassi, Nourdin Harich, Mariama Lasky, Hasna Boura","doi":"10.1007/s10096-025-05192-8","DOIUrl":"10.1007/s10096-025-05192-8","url":null,"abstract":"<p><strong>Purpose: </strong>Heterogeneity in the vacA and cagA pathogenicity factors of Helicobacter pylori has been correlated with the progression and the severity of gastrointestinal disease in adults; however, data regarding these markers in the pediatric population remain limited. The objective of this research was to assess the distribution of the vacA and cagA virulence markers in symptomatic Moroccan children and adolescents, as well as their association with histologic and endoscopic findings.</p><p><strong>Materials and methods: </strong>Gastric tissue samples were retrieved from two hundred children and adolescents referred for upper gastrointestinal endoscopy. Conventional PCR was employed to detect H. pylori infection and the presence of the cagA gene, whereas multiplex-PCR was used to characterize the vacA allelic variants (s and m alleles).</p><p><strong>Results: </strong>From the 200 children and adolescents involved in this research, 84,5% tested positive for H. pylori. Among these,32% carried the cagA gene, and vacA was identified in all H. pylori strains. The most prevalent gnotype combination was the vacA s2/m2 genotype, affecting 67.5% of the infected patients, followed by s1/m2 (16%), s1/m1 (14.7%), with the vacA s2/m1 being the rarest genotype (1.8%). Gastric nodularity was frequently observed in patients harboring cagA-positive strains. A meaningful association was noted between H. pylori colonisation density and the vacA s1 and m1 genotypes. Histological findings showed no significant variation according to vacA and cagA genotypes.</p><p><strong>Conclusion: </strong>Our results showed that H. pylori strains harboring the vacA s2 m2 and cagA-negative genotypes were the most frequently detected among children and adolescents in our country. Larger-scale studies are needed to investigate the potential clinical relevance of other virulence markers in the progression of this infection among pediatric patients in our country.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2253-2261"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence trends and epidemiology of invasive device-associated bacteremia in French nursing home residents, 2020-2024: Insights from the SPIADI Prospective Multicenter Study.","authors":"Maris Dussartre, Nicolas Duflot, Anne-Sophie Valentin, Mathilde Farizon, Florent Goube, Nathalie van der Mee-Marquet","doi":"10.1007/s10096-025-05188-4","DOIUrl":"10.1007/s10096-025-05188-4","url":null,"abstract":"<p><p>Healthcare-associated bacteremia is associated with increased morbidity and mortality. In nursing homes, these infections remain under-documented. We investigated invasive device-associated bacteremia in residents. We analyzed bacteremias acquired in nursing homes using data from a national surveillance program conducted between 2020 and 2024, involving 1,233 French healthcare institutions. A total of 2,117 bacteremias acquired in the nursing home were recorded. The main sources of infection were the urinary tract (52.1%) and the respiratory tract (11.9%). An invasive device was involved in 20.0% of cases, primarily urinary catheters (386 cases), while bacteremia related to intravascular devices was rare (38 cases). Enterobacterales (64.0%) and Staphylococcus aureus (14.6%) were the most frequently identified pathogens, with multidrug-resistant bacteria detected in 15.2% of nursing home-acquired bacteremias. The incidence rate was 0.009 per 1,000 resident-days, remaining stable over the study period. The study highlights the burden of bacteremias in nursing homes and underscores the importance of targeted infection prevention measures, particularly in relation to urinary catheter management, and long-term intravascular central lines.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":"2219-2230"},"PeriodicalIF":3.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12457500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144368714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sharp increase in Chlamydia pneumoniae infections in 2024 in Germany.","authors":"Sébastien Boutin, Andi Krumbholz, Tobias Siegfried Kramer, Michael Boehm, Norbert Schmeisser, Rolf Kaiser, Jan Rupp","doi":"10.1007/s10096-025-05244-z","DOIUrl":"https://doi.org/10.1007/s10096-025-05244-z","url":null,"abstract":"<p><p>Chlamydia pneumoniae (C. pneumoniae) is a recognized cause of respiratory infections in children and adolescents, while it is often considered a negligible pathogen in adults outside of outbreaks. We performed a retrospective analysis from a nationwide surveillance network in Germany that collected data from 2018 to 2024. A multivariate analysis (binomial model) was performed to assess the influence of year, hospitalization status, gender and age on C. pneumoniae detection rate. Our analysis showed an increasing C. pneumoniae detection rate in 2024 compared to 2019, especially in children below 15 years and adults aged 30-50 years, mostly in patients who were treated as outpatients.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the value of novel inflammatory indicators derived from complete blood count in predicting for pertussis in children.","authors":"Jianyong Tang, Fang Wu, You Wu, Congcong Chen, Peiwen Ning, Wei Wang, Jianfei Shi, Xingyan Guo, Zengguo Wang","doi":"10.1007/s10096-025-05241-2","DOIUrl":"https://doi.org/10.1007/s10096-025-05241-2","url":null,"abstract":"<p><strong>Objective: </strong>Inflammatory indicators derived from complete blood count (CBC) have been shown to exhibit substantial clinical utility across a broad spectrum of infectious and inflammatory conditions, this study aimed to explore the potential value of CBC-derived inflammatory indicators in predicting for pertussis in children.</p><p><strong>Methods: </strong>CBC parameters of all the participants included in this study were collected. The CBC-derived inflammatory indicators evaluated included the neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), [neutrophil + monocyte]-to-lymphocyte ratio (NMLR), systemic immune-inflammation index (SII), and systemic inflammatory response index (SIRI). The predictive value of CBC-derived inflammatory indicators was assessed using the receiver operating characteristic (ROC) curve analysis.</p><p><strong>Results: </strong>A total of 892 pertussis children, 903 children with non-pertussis respiratory tract infection and 1,165 healthy children were included in this study. Compared to healthy children, the PLR in children with pertussis was significantly reduced (p < 0.001), whereas the levels of the other indicators were significantly increased. Simultaneously, the indicators in children with pertussis were significantly lower than those in children with non-pertussis infection. In the comparative analysis of inflammatory indicators across different age subgroups, all indicators in the pertussis group were significantly elevated in children < 2 years old, compared to those in both the non-pertussis group and the healthy group; conversely, in children > 2 years old, these indicators were significantly lower than those observed in the non-pertussis group. The ROC analysis results indicated that, aside from PLR, the CBC-derived inflammatory indicators demonstrated significant value in predicting for pertussis infection in children < 2 years old. Furthermore, the integration of multiple markers could enhance diagnostic performance.</p><p><strong>Conclusion: </strong>CBC-derived inflammatory indicators, particularly NLR and NMLR, may serve as valuable tools for early predicting for pertussis in children under 2 years old in clinical practice.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Etiological characteristics of Mycoplasma pneumoniae infection and macrolide resistance in children in beijing: a retrospective study from 2018 to 2024.","authors":"Wanning Chen, Hui Qi, Weiwei Jiao, Yajie Guo, Yuqing Wang, Jinrong Liu, Baoping Xu, Chengsong Zhao, Lin Sun","doi":"10.1007/s10096-025-05230-5","DOIUrl":"https://doi.org/10.1007/s10096-025-05230-5","url":null,"abstract":"<p><strong>Background: </strong>Mycoplasma pneumoniae (MP) is a major cause of pediatric respiratory tract infections (RTIs), with recent increases in incidence and macrolide resistance. The epidemiology of MP, macrolide-resistant MP (MRMP), co-infection patterns, and their relationship with disease severity in the post-COVID era remain poorly understood. We analyzed temporal trends in MP infection and MRMP prevalence and assessed their association with severe community-acquired pneumonia (SCAP).</p><p><strong>Methods: </strong>Children aged < 18 years hospitalized with RTIs at Beijing Children's Hospital were retrospectively enrolled during 2018-2024. Respiratory samples were tested for MP and macrolide resistance mutations. Data on co-infecting bacterial and viral pathogens were collected in clinical practice and retrospectively included in this study. We analyzed temporal trends and risk factors for SCAP.</p><p><strong>Results: </strong>Among 8,453 children, MP-positive patients accounted for 39.7%, declining to 17.0% in 2021 and rising sharply to 62.8% in 2024. The highest MP-positivity rates were seen in children aged 5-9 years, although a notable increase occurred in children aged < 5 years in 2024. MRMP was detected in 96.9% of MP-positive cases, with resistance rates > 95% from 2022. After 2021, co-infections were detected in 19.9% of cases tested for bacterial and viral pathogens, most commonly involving human rhinovirus-MP, Haemophilus influenzae-MP, and Streptococcus pneumoniae-MP. Risk factors for SCAP included female sex, age > 5 years, cold season onset, pure MP infection, and MP co-infection. MRMP was not an independent predictor of SCAP.</p><p><strong>Conclusions: </strong>The burden of MP infection has resurged post-COVID, with sustained high macrolide resistance and evolving co-infection patterns. Our findings underscore the importance of ongoing surveillance and tailored management strategies for pediatric MP infections.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a digital remote extraction analysis and monitoring tool for key performance indicators (KPIs) in the blood culture process.","authors":"Claudio Palmieri, Laura Bartolini, Andrea Berlingeri, Barbara Camilloni, Gianfranco La Bella, Michela Pascarella, Marina Selleri, Felice Valzano, Chiara Vismara, Simone Ambretti, Carla Fontana, Mario Rassu, Gian Maria Rossolini, Fabio Arena, Antonella Mencacci","doi":"10.1007/s10096-025-05238-x","DOIUrl":"https://doi.org/10.1007/s10096-025-05238-x","url":null,"abstract":"<p><strong>Purpose: </strong>Bloodstream infections (BSIs) pose a significant health threat, requiring effective diagnostic processes to ensure appropriate treatment. Monitoring the quality of blood cultures (BCs) process (the cornerstone of BSIs etiological diagnosis) is critical. This study aimed to describe an automated tool, BD DREAM™ (Digital Remote Extraction Analysis & Monitoring), designed for monitoring key performance indicators (KPIs) in the BCs process.</p><p><strong>Methods: </strong>A multicenter study was conducted across six Italian hospitals, analyzing 234,978 BC bottles, associated with 55,819 episodes. The system monitored KPIs related to mean blood volume per bottle, rates of solitary episodes, rate of BCs from central venous catheter (CVC) unpaired with concomitant BCs from peripheral vein, and contamination rates.</p><p><strong>Results: </strong>The findings highlighted significant variability in BC practices among centers and hospital services, with mean blood volume per bottle below recommended standards (6.45 mL vs. ≥ 8.0 mL), with 21.8% (range 3.2-62.9%) of episodes classified as solitary. The rate of BCs from CVC unpaired with concomitant BCs from peripheral vein was 14.9% (range 10.2-39.0%). Overall, contamination rates ranged from 4.2 to 4.7%, depending on the criteria adopted for definition. The setting with the more critical values was medical area.</p><p><strong>Conclusion: </strong>The tool was useful for immediate visualization and identification of hospital services with critical performance. These results suggest that integrating BC digital monitoring tools into clinical microbiology workflows is possible. Further studies will be needed to demonstrate that the implementation of BD DREAM™ can lead to enhancement of diagnostic accuracy, optimization of resources allocation, and improvement of patient outcomes.</p>","PeriodicalId":11782,"journal":{"name":"European Journal of Clinical Microbiology & Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144872058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}