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Cryptotanshinone Suppresses the STAT3/BCL-2 Pathway to Provoke Human Bladder Urothelial Carcinoma Cell Death. 隐丹参酮抑制 STAT3/BCL-2 通路以诱导人膀胱尿路癌细胞死亡
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-27 DOI: 10.1002/tox.24446
Min-Che Tung, Ge-Man Chang, Wen-Chyi Dai, Chen-Hsuan Hsu, Hsiang-Chun Chang, Wei-Ting Yang, Yann-Jen Ho, Chien-Hsing Lu, Yi-Hsin Chen, Chia-Che Chang
{"title":"Cryptotanshinone Suppresses the STAT3/BCL-2 Pathway to Provoke Human Bladder Urothelial Carcinoma Cell Death.","authors":"Min-Che Tung, Ge-Man Chang, Wen-Chyi Dai, Chen-Hsuan Hsu, Hsiang-Chun Chang, Wei-Ting Yang, Yann-Jen Ho, Chien-Hsing Lu, Yi-Hsin Chen, Chia-Che Chang","doi":"10.1002/tox.24446","DOIUrl":"https://doi.org/10.1002/tox.24446","url":null,"abstract":"<p><p>Bladder cancer is one of the most common human malignancies worldwide. Aberrant activation of signal transducer and activator of transcription 3 (STAT3) is crucial to driving malignant progression and predicting poor prognosis of multiple human cancers, including bladder cancer, making STAT3 a promising target of cancer therapeutics. Cryptotanshinone (CTS) is an anticancer ingredient of Danshen (Salvia miltiorrhiza), a top-graded Chinese medicinal herb. However, whether CTS targets STAT3 to exert its cytotoxic effect on human bladder cancer remains unknown. Herein, we demonstrated that CTS is cytotoxic to multiple human urinary bladder transitional cell carcinoma (TCC) cell lines while sparing normal human urothelial cells. CTS provoked apoptosis-dependent bladder TCC cytotoxicity, as apoptosis blockage by z-VAD-fmk markedly rescued the clonogenicity of CTS-treated cells. Besides, CTS was found to suppress constitutive and interleukin 6-inducible activation of STAT3, evidenced by the downregulation of STAT3 tyrosine 705 phosphorylation and BCL2, a recognized STAT3 transcriptional target. Notably, ectopic expression of a dominant-active STAT3 mutant (STAT3-C) or BCL-2 alleviated CTS-induced apoptosis and clonogenicity inhibition, thus confirming STAT3 blockade as a pivotal mechanism of CTS's cytotoxic action on bladder TCC cells. Lastly, immunoblotting revealed that CTS lowered the levels of active JAK2, an upstream kinase that mediates STAT3 tyrosine 705 phosphorylation. Altogether, we conclude that the blockade of the JAK2/STAT3/BCL-2 antiapoptotic signaling axis is a vital mechanism whereby CTS provokes bladder cancer cytotoxicity. The current evidence implicates CTS's potential to be translated into a bladder cancer therapeutic agent.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142727311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Difference in Histopathological and Steroidogenesis Metabolism of Zebrafish After Exposure to Spiromesifen. 暴露于司来美芬后斑马鱼组织病理学和类固醇代谢的性别差异
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-26 DOI: 10.1002/tox.24438
Jie Zhang, Yang Yang, Yongmei Fan, Wang Yu, Le Qian, Manman Duan, Wentian Zhao, Xiangguang Chen, Wanhui Song, Xuefeng Li, Chengju Wang
{"title":"Sex Difference in Histopathological and Steroidogenesis Metabolism of Zebrafish After Exposure to Spiromesifen.","authors":"Jie Zhang, Yang Yang, Yongmei Fan, Wang Yu, Le Qian, Manman Duan, Wentian Zhao, Xiangguang Chen, Wanhui Song, Xuefeng Li, Chengju Wang","doi":"10.1002/tox.24438","DOIUrl":"https://doi.org/10.1002/tox.24438","url":null,"abstract":"<p><p>Spiromesifen (SPM) is widely used for orchard mites and white fly control. The ecotoxicological data suggested that SPM is highly toxic to fish, but the information about its toxic effect on zebrafish is still obscure. In this study, adult zebrafish were exposed to SPM for 21 days. The plasma sex steroid hormone levels reflected the ratio of 17β-estradiol (E2) to testosterone (T) (E2/T) was significantly increased at 0.50 μg/L of SPM in male fish (2.4-fold, p = 0.049). Following 21 days' post exposure, distinct pathological changes were noted in gonad, males were more sensitive than female, which showed the interstitial connective tissue hyperplasia and widener in testis at 15 μg/L of SPM. In male fish, the relative percentage of spermatozoa was 13% decreased at 30 μg/L of SPM (p = 0.041). Which suggest SPM potential role in disrupting male gonad development. qRT-PCR results suggest that expression of follicle stimulating hormone receptor (fshr) was significantly down regulated in female zebrafish (0.29 fold of control, p = 0.010). Variable importance of projection (VIP) scores indicate the most important features separate in female and male. The different response of steroid level towards SPM between male and female zebrafish may due to the distinct regulation of key genes related in steroidogenesis and metabolism. This study for the first time connects the biochemical and histological to reveal the adverse effects of SPM on adult zebrafish in a sex dependent manner.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death After Myocardial Infarction Through β1 Adrenergic Receptor. 回放：苯乙酰谷氨酰胺（PAGln）通过β1肾上腺素能受体增强心肌梗死后心肌细胞的死亡。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24454
{"title":"RETRACTION: Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death After Myocardial Infarction Through β1 Adrenergic Receptor.","authors":"","doi":"10.1002/tox.24454","DOIUrl":"https://doi.org/10.1002/tox.24454","url":null,"abstract":"<p><strong>Retraction: </strong>H. Xu, N. Yang, B.Y. Wang, L. Zhou, L.L. Xu, Y. Chen, D.J. Wang, and W.H. Ge, \"Phenylacetyl Glutamine (PAGln) Enhances Cardiomyocyte Death after Myocardial Infarction through β1 Adrenergic Receptor,\" Environmental Toxicology 39, no. 3 (2024): 1682-1699, https://doi.org/10.1002/tox.24063. The above article, published online on 02 December 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. In addition, the investigation found there was significant unattributed textual overlap between this article and a previously-published article (Beale et al., 2008; https://doi.org/10.1186/1471-2407-8-200). Therefore, the article must be retracted. The authors Weihong Ge and Hang Xu disagree with this decision. The other authors did not respond.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Efficacy of Three‐Dimensional Arterial Spin Labeling and How it Compares Against That of Contrast Enhanced Magnetic Resonance Imaging in Preoperative Grading of Brain Gliomas 回放：三维动脉自旋标记的疗效及其与对比增强磁共振成像在脑胶质瘤术前分级中的比较
IF 4.5 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24452
{"title":"RETRACTION: Efficacy of Three‐Dimensional Arterial Spin Labeling and How it Compares Against That of Contrast Enhanced Magnetic Resonance Imaging in Preoperative Grading of Brain Gliomas","authors":"","doi":"10.1002/tox.24452","DOIUrl":"https://doi.org/10.1002/tox.24452","url":null,"abstract":"<jats:mixed-citation publication-type=\"journal\">RETRACTION: <jats:string-name><jats:given-names>K.</jats:given-names> <jats:surname>Wang</jats:surname></jats:string-name>, <jats:string-name><jats:given-names>H.</jats:given-names> <jats:surname>Guo</jats:surname></jats:string-name>, <jats:string-name><jats:given-names>X.</jats:given-names> <jats:surname>Tian</jats:surname></jats:string-name>, <jats:string-name><jats:given-names>Y.</jats:given-names> <jats:surname>Miao</jats:surname></jats:string-name>, <jats:string-name><jats:given-names>P.</jats:given-names> <jats:surname>Han</jats:surname></jats:string-name>, and <jats:string-name><jats:given-names>F.</jats:given-names> <jats:surname>Jin</jats:surname></jats:string-name>, “,” <jats:source>Environmental Toxicology</jats:source> <jats:volume>38</jats:volume>, no. (<jats:year>2023</jats:year>): <jats:fpage>1723</jats:fpage>–<jats:lpage>1731</jats:lpage>, <jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"https://doi.org/10.1002/tox.23800\">https://doi.org/10.1002/tox.23800</jats:ext-link>.</jats:mixed-citation>The above article, published online on 11 April 2023, in Wiley Online Library (<jats:ext-link xmlns:xlink=\"http://www.w3.org/1999/xlink\" xlink:href=\"http://onlinelibrary.wiley.com/\">http://onlinelibrary.wiley.com/</jats:ext-link>), has been retracted by agreement between the journal Editor‐in‐Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The author Feng Jin disagrees with this decision. The other authors did not respond.","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":"12 1","pages":""},"PeriodicalIF":4.5,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142697032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Exploring the Role of Lactylation-Related Genes in Osteosarcoma: A Deep Dive Into Prognostic Significance and Therapeutic Potential. 回放：探索乳化相关基因在骨肉瘤中的作用：深入探讨预后意义和治疗潜力。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24449
{"title":"RETRACTION: Exploring the Role of Lactylation-Related Genes in Osteosarcoma: A Deep Dive Into Prognostic Significance and Therapeutic Potential.","authors":"","doi":"10.1002/tox.24449","DOIUrl":"https://doi.org/10.1002/tox.24449","url":null,"abstract":"<p><strong>Retraction: </strong>J. Sun, Y. Li, R. Chen, Y. Xie, J. Wei, and B. Li, \"Exploring the Role of Lactylation-Related Genes in Osteosarcoma: A Deep Dive into Prognostic Significance and Therapeutic Potential,\" Environmental Toxicology 39, no. 2 (2023): 1001-1017, https://doi.org/10.1002/tox.24011. The above article, published online on 27 November 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Neurological Risks Arising From the Bioaccumulation of Heavy Metal Contaminants: A Focus on Mercury. 回放：重金属污染物的生物累积对神经系统造成的风险：聚焦汞。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24450
{"title":"RETRACTION: Neurological Risks Arising From the Bioaccumulation of Heavy Metal Contaminants: A Focus on Mercury.","authors":"","doi":"10.1002/tox.24450","DOIUrl":"https://doi.org/10.1002/tox.24450","url":null,"abstract":"<p><strong>Retraction: </strong>T. Dong and H. Li, \"Neurological Risks Arising from the Bioaccumulation of Heavy Metal Contaminants: A Focus on Mercury,\" Environmental Toxicology 39, no. 5 (2024): 2692-2705, https://doi.org/10.1002/tox.24119. The above article, published online on 19 January 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142708870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Prognostic Value and Potential Mechanism of Cellular Senescence and Tumor Microenvironment in Hepatocellular Carcinoma: Insights From Bulk Transcriptomics and Single-Cell Sequencing Analysis. 回放：肝细胞癌中细胞衰老和肿瘤微环境的预后价值和潜在机制：大宗转录组学和单细胞测序分析的启示
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24453
{"title":"RETRACTION: Prognostic Value and Potential Mechanism of Cellular Senescence and Tumor Microenvironment in Hepatocellular Carcinoma: Insights From Bulk Transcriptomics and Single-Cell Sequencing Analysis.","authors":"","doi":"10.1002/tox.24453","DOIUrl":"https://doi.org/10.1002/tox.24453","url":null,"abstract":"<p><strong>Retraction: </strong>C. Qu, Q. Wu, J. Lu, and F. Li, \"Prognostic Value and Potential Mechanism of Cellular Senescence and Tumor Microenvironment in Hepatocellular Carcinoma: Insights from Bulk Transcriptomics and Single-Cell Sequencing Analysis,\" Environmental Toxicology 39, no. 5 (2024): 2512-2527, https://doi.org/10.1002/tox.24121. The above article, published online on 08 January 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Development of the ARDS-Derived Gene Panel for Lung Adenocarcinoma Prognosis Stratification and Experiment Validation of CCL20 Expression. RETRACTION：开发用于肺腺癌预后分层的 ARDS 衍生基因面板，并对 CCL20 表达进行实验验证。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24456
{"title":"RETRACTION: Development of the ARDS-Derived Gene Panel for Lung Adenocarcinoma Prognosis Stratification and Experiment Validation of CCL20 Expression.","authors":"","doi":"10.1002/tox.24456","DOIUrl":"https://doi.org/10.1002/tox.24456","url":null,"abstract":"<p><p>Retraction: J. Fang, C. Shi, Q. Huang, L. Huang, X. Wang, and B. Yan, \"Development of the ARDS-Derived Gene Panel for Lung Adenocarcinoma Prognosis Stratification and Experiment Validation of CCL20 Expression,\" Environmental Toxicology 39, no. 5 (2024): 3211-3224, https://doi.org/10.1002/tox.24161. The above article, published online on 14 February 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The author Biqing Yan disagrees with this decision. The other authors did not respond.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: Exploring the Tumor Microenvironment: Chemokine-Related Genes and Immunotherapy/Chemotherapy Response in Clear-Cell Renal Cell Carcinoma. RETRACTION：探索肿瘤微环境：化疗因子相关基因与透明细胞肾细胞癌的免疫疗法/化疗反应。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24455
{"title":"RETRACTION: Exploring the Tumor Microenvironment: Chemokine-Related Genes and Immunotherapy/Chemotherapy Response in Clear-Cell Renal Cell Carcinoma.","authors":"","doi":"10.1002/tox.24455","DOIUrl":"https://doi.org/10.1002/tox.24455","url":null,"abstract":"<p><p>Retraction: Y. Meng, C. Zhang, T. Fu, J. He, J. Wu, and Y. Zhan, \"Exploring the Tumor Microenvironment: Chemokine-Related Genes and Immunotherapy/Chemotherapy Response in Clear-Cell Renal Cell Carcinoma,\" Environmental Toxicology (EarlyView): https://doi.org/10.1002/tox.24190. The above article, published online on 15 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETRACTION: DPM2 Serve as Novel Oncogene and Prognostic Marker Transactivated by ESR1 in Breast Cancer. 返回：DPM2 是由 ESR1 在乳腺癌中反式激活的新型癌基因和预后标志物。
IF 4.4 3区 医学
Environmental Toxicology Pub Date : 2024-11-25 DOI: 10.1002/tox.24451
{"title":"RETRACTION: DPM2 Serve as Novel Oncogene and Prognostic Marker Transactivated by ESR1 in Breast Cancer.","authors":"","doi":"10.1002/tox.24451","DOIUrl":"https://doi.org/10.1002/tox.24451","url":null,"abstract":"<p><strong>Retraction: </strong>J. Lu, Y. Feng, Y. Zhou, Z. Xiao, Z. Yang, J. Li, H. Cai, and J. Wang, \"DPM2 Serve as Novel Oncogene and Prognostic Marker Transactivated by ESR1 in Breast Cancer,\" Environmental Toxicology 39, no. 3 (2024): 1737-1746, https://doi.org/10.1002/tox.24059. The above article, published online on 05 December 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor-in-Chief, Paul B. Tchounwou; and Wiley Periodicals LLC. Following an investigation by the publisher, the parties have concluded that this article was accepted solely on the basis of a compromised peer review process. Therefore, the article must be retracted. The author Jie Wang disagrees with this decision. The other authors did not respond.</p>","PeriodicalId":11756,"journal":{"name":"Environmental Toxicology","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142709791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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