Epilepsy Currents最新文献_第4页

Prepregnancy Education: A Gap in Care for All. 孕前教育：人人享有保健的差距。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-18 DOI: 10.1177/15357597251351210

Danielle A Becker

引用次数: 0

Deep Brain, Deep Impact: Rethinking Pediatric Epilepsy Treatment With Deep Brain Stimulation of the Centromedian Nucleus. 深部脑，深部影响：重新思考小儿癫痫治疗与深部脑正中核刺激。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-16 DOI: 10.1177/15357597251351452

Anthony L Fine

引用次数: 0

Treating Neuropsychiatric Conditions in Pediatric Epilepsy: Practical Considerations. 治疗小儿癫痫的神经精神疾病：实际考虑。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-16 DOI: 10.1177/15357597251350031

D Dilara Ertenu, Jay A Salpekar

引用次数: 0

Forged Without FIRE: Normal Brain Development in the Absence of Microglia. 没有火的锻造：没有小胶质细胞的正常大脑发育。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-16 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251348961

Nicholas H Varvel

引用次数: 0

Developmental Outcome at 36 Months in Tuberous Sclerosis: Are There any Modifiable Predictors? 结节性硬化症36个月的发育结局：是否有任何可修改的预测因子？

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-16 DOI: 10.1177/15357597251351453

Charuta Joshi

引用次数: 0

Evaluation, Diagnosis, and Treatment of Concomitant Movement Disorders in Genetic Epilepsies. 遗传性癫痫伴发运动障碍的评估、诊断和治疗。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-16 DOI: 10.1177/15357597251323917

Jordan Garris, Megan Abbott, Erika Axeen, Laura Tochen, John M Schreiber

{"title":"Evaluation, Diagnosis, and Treatment of Concomitant Movement Disorders in Genetic Epilepsies.","authors":"Jordan Garris, Megan Abbott, Erika Axeen, Laura Tochen, John M Schreiber","doi":"10.1177/15357597251323917","DOIUrl":"10.1177/15357597251323917","url":null,"abstract":"Genetic epilepsies and developmental and epileptic encephalopathies are commonly associated with concomitant movement disorders, which can mimic seizures and/or create additional disability. Appropriate diagnosis is critical to proper management. A broad range of movement disorder phenomenologies occur among patients with genetic epilepsy, including dystonia, chorea, ataxia, myoclonus, stereotypy, tics, and Parkinsonism. For some genes, clear relationships exist between genotype and movement disorder phenotype, while in other situations, the relationship is more complex. Diagnosis of movement disorders involves elements of history, physical examination, video review, and neurophysiology. Assessment of associated impairment, distress, and/or safety concerns is important for considering risks/benefits of treatment. Movement disorders may range from severe and dangerous, requiring pharmacologic or neuromodulatory treatments such as deep brain stimulation, to relatively benign, with only reassurance and continued observation required. Appropriate treatments differ based on phenomenology and etiology, with some genes associated with tailored treatments which can provide dramatic benefit.","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251323917"},"PeriodicalIF":5.8,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rebuilding the Tower of Babel: The Current Landscape and Emerging Opportunities in DEE-SWAS. 重建巴别塔：dei - swas的现状和新兴机遇。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-09 DOI: 10.1177/15357597251344191

Robert C Stowe, Sarah A Kelley, Sonal Bhatia, John R McLaren, Lekha M Rao, Shital H Patel, Anthony L Fine, Fiona Baumer, Priscilla Duong, Spriha Pavuluri, Virginia B Liu, Donald J Phillips

{"title":"Rebuilding the Tower of Babel: The Current Landscape and Emerging Opportunities in DEE-SWAS.","authors":"Robert C Stowe, Sarah A Kelley, Sonal Bhatia, John R McLaren, Lekha M Rao, Shital H Patel, Anthony L Fine, Fiona Baumer, Priscilla Duong, Spriha Pavuluri, Virginia B Liu, Donald J Phillips","doi":"10.1177/15357597251344191","DOIUrl":"10.1177/15357597251344191","url":null,"abstract":"Developmental/epileptic encephalopathy with spike-wave activation in sleep (DEE-SWAS) is newly proposed nomenclature put forth by the International League Against Epilepsy (ILAE) to replace the problematic electrographic and/or clinical phenotypes of electrical status epilepticus of sleep (ESES) and continuous spike-wave in sleep (CSWS). The nomenclature update represents a noble effort to minimize the confusion of how to define and appropriately utilize this alphabet soup of acronyms, thereby aiding in future clinical and research efforts. The name change fails to capture greater challenges within the field, which still plague diagnosis and treatment and stagnates substantive research advancements. Through a directed literature review of DEE-SWAS with emphasis on the new ILAE nomenclature and the RESCUE-ESES trial, we will highlight major persistent quandaries in the field. These include inadequate or insufficient diagnostic biomarkers (ie, the spike wave index), the highly variable clinical manifestations, ranging from dubious associations to profound developmental regression, presumptively caused by spike-wave activation in sleep, and variable and often ineffective treatment paradigms. We will also review the broader diagnostic evaluation of DEE-SWAS. By doing so, we aim to shed light on crucial research and clinical questions that could advance our understanding of diagnosing and treating children with DEE-SWAS, as well as addressing the uncertainty surrounding the neurological effects of sleep-activated epileptiform discharges.","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251344191"},"PeriodicalIF":5.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

American Epilepsy Society/International League Against Epilepsy-North America Joint Task Force for Epilepsy Health Care Disparities in the United States. 美国癫痫协会/国际抗癫痫联盟-美国癫痫保健差异北美联合工作队。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-09 DOI: 10.1177/15357597251342227

Jaideep Kapur, Dave Clarke, Mill Etienne, Camilo Gutierrez, Barbara C Jobst, Emily Johnson, Sucheta Joshi, Elaine T Kiriakopoulos, David M Labiner, Fred A Lado, Alain Lekoubou, Daniel H Lowenstein, Karen Parko, Ellen Riker, Renée A Shellhaas, Joseph I Sirven, Karen Skjei, John M Stern, Timothy E Welty, Adam B Eickmeyer, Shawna L Strickland

{"title":"American Epilepsy Society/International League Against Epilepsy-North America Joint Task Force for Epilepsy Health Care Disparities in the United States.","authors":"Jaideep Kapur, Dave Clarke, Mill Etienne, Camilo Gutierrez, Barbara C Jobst, Emily Johnson, Sucheta Joshi, Elaine T Kiriakopoulos, David M Labiner, Fred A Lado, Alain Lekoubou, Daniel H Lowenstein, Karen Parko, Ellen Riker, Renée A Shellhaas, Joseph I Sirven, Karen Skjei, John M Stern, Timothy E Welty, Adam B Eickmeyer, Shawna L Strickland","doi":"10.1177/15357597251342227","DOIUrl":"10.1177/15357597251342227","url":null,"abstract":"Numerous factors including social determinants of health, knowledge gaps, economic challenges, workforce limitations, and health system deficiencies are associated with significant disparities in access to health care services and health outcomes for people with epilepsy (PWE). The American Epilepsy Society (AES) and the International League Against Epilepsy-North America (ILAE-NA) established a joint task force to explore and develop recommendations to address health care disparities experienced by PWE. The task force gathered foundational knowledge through meetings, public and patient organization comments and discussions to develop consensus recommendations. We enumerate the recommendations and discuss the rationale behind them to reduce disparities in epilepsy care through comprehensive research, inclusive clinical practices, robust advocacy, and targeted educational initiatives. While our recommendations are focused on the United States, we acknowledge that similar barriers and limitations exist for PWE globally and that these also need to be addressed within their local domains and with attention to unique factors therewithin.","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251342227"},"PeriodicalIF":5.8,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

How Can Animal Models Advance Research into High Frequency Oscillations: Guidelines for Recording, Detection and Analysis. 动物模型如何推进高频振荡研究：记录、检测和分析指南。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-09 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251336792

Christos Panagiotis Lisgaras, Richard J Staba, Liset M de la Prida

引用次数: 0

Rhythmic Quakes Shock the Cortical Focus Theory. 节律性地震冲击皮层焦点理论。

IF 5.8 2区医学

Epilepsy Currents Pub Date : 2025-06-08 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251314673

Jacob M Hull, John R Huguenard

引用次数: 0