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Epilepsy Currents最新文献

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Is a Video Worth a Thousand EEGs? 一段视频值一千个鸡蛋吗？
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261475320
Danielle A Becker
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引用次数: 0
Neurocentric No More? Oligodendrocyte Dysfunction Supports Epileptogenesis. 不再以神经为中心？少突胶质细胞功能障碍支持癫痫发生。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261459801
Gabriel B Miller-Oskolkoff, Manoj K Patel
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引用次数: 0
Ketogenic Diet Extinguishes Firing at the Synapses. 生酮饮食抑制突触的放电。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261468567
Bin Gu
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引用次数: 0
A Change of Heart for DEPDC5: Expanding the Neurocardiac Hypothesis of SUDEP. DEPDC5的心脏改变：扩展SUDEP的神经心脏假说。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261474065
Edward Glasscock
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引用次数: 0
Decades of Epilepsy Surgery Follow-up: What's Known and What's Not? 几十年的癫痫手术随访：什么是已知的，什么是未知的？
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261475303
Taylor J Abel
{"title":"Decades of Epilepsy Surgery Follow-up: What's Known and What's Not?","authors":"Taylor J Abel","doi":"10.1177/15357597261475303","DOIUrl":"10.1177/15357597261475303","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261475303"},"PeriodicalIF":4.6,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rewriting SCN1A: Genome Editing for Genetic Epilepsies. 重写SCN1A：基因癫痫的基因组编辑。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261475312
Samantha A Dow, Tracy A Bedrosian
{"title":"Rewriting SCN1A: Genome Editing for Genetic Epilepsies.","authors":"Samantha A Dow, Tracy A Bedrosian","doi":"10.1177/15357597261475312","DOIUrl":"10.1177/15357597261475312","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261475312"},"PeriodicalIF":4.6,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frailty and Late-Onset Epilepsy: Two Clinical Faces of Biological Aging? 虚弱和晚发性癫痫：生物学衰老的两种临床特征？
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-08-10 DOI: 10.1177/15357597261474773
Vineet Punia
{"title":"Frailty and Late-Onset Epilepsy: Two Clinical Faces of Biological Aging?","authors":"Vineet Punia","doi":"10.1177/15357597261474773","DOIUrl":"10.1177/15357597261474773","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261474773"},"PeriodicalIF":4.6,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13457407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modeling Epilepsies with Human Brain Organoids: Recent Advances and Ongoing Challenges. 用人脑类器官模拟癫痫：最近的进展和正在进行的挑战。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-07-28 DOI: 10.1177/15357597261469411
Miranda P Walker, Jack M Parent
{"title":"Modeling Epilepsies with Human Brain Organoids: Recent Advances and Ongoing Challenges.","authors":"Miranda P Walker, Jack M Parent","doi":"10.1177/15357597261469411","DOIUrl":"10.1177/15357597261469411","url":null,"abstract":"<p><p>Epilepsy is a common and heterogeneous group of neurologic disorders characterized by recurrent unprovoked seizures. With a diverse array of genetic and acquired etiologies, the mechanisms linking insults to epileptogenesis and network hyperexcitability remain poorly understood. Although animal models have provided critical insights into seizure generation and disease mechanisms, differences in human cortical development and limitations in recapitulating spontaneous seizure phenotypes observed in patients highlight the need to develop complementary human-based models. Human pluripotent stem cell-derived brain organoids, including patient-derived and CRISPR-engineered models, offer an increasingly powerful human-specific platform to investigate epilepsy-associated disruptions in neuronal production and differentiation, interneuron migration, and network activity. In this review, we discuss recent advances and ongoing challenges of human cortical organoid models of genetic and acquired epilepsies. Together with established animal models, organoid-based approaches hold promise for advancing mechanistic understanding of epilepsy and enabling the development of more precise therapeutic strategies.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261469411"},"PeriodicalIF":4.6,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13415638/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Moving in Tandem: Epilepsy-Dyskinesia Syndromes. 串联运动：癫痫-运动障碍综合征。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-07-27 DOI: 10.1177/15357597261471340
Peter Widdess-Walsh
{"title":"Moving in Tandem: Epilepsy-Dyskinesia Syndromes.","authors":"Peter Widdess-Walsh","doi":"10.1177/15357597261471340","DOIUrl":"10.1177/15357597261471340","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261471340"},"PeriodicalIF":4.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Starting Young: Responsive Neurostimulation in Children. 从年轻开始：儿童反应性神经刺激。
IF 4.6 2区 医学
Epilepsy Currents Pub Date : 2026-07-27 DOI: 10.1177/15357597261468968
Shruti Agashe
{"title":"Starting Young: Responsive Neurostimulation in Children.","authors":"Shruti Agashe","doi":"10.1177/15357597261468968","DOIUrl":"10.1177/15357597261468968","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597261468968"},"PeriodicalIF":4.6,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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