Egyptian Journal of Radiation Sciences and Applications最新文献_第5页

Reform of Hematopoietic, Apoptotic and Oxidative Disturbance Induced by Accumulated γ-Irradiation in Rat’s Bone Marrow via Curative Efficacy of Bradykinin Potentiating Factor Isolated from Bee Venom 蜂毒缓激肽增强因子对γ-累积照射所致大鼠骨髓造血、细胞凋亡和氧化障碍的影响

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2021-09-27 DOI: 10.21608/ejrsa.2021.89718.1121

H. Hasan, S. Galal

引用次数: 0

Fast Procedure for Aqueous Samples Investigation Using SEM and EDX for Nuclear Safeguards Purposes 用于核保障目的的扫描电镜和EDX快速水样调查程序

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2020-12-23 DOI: 10.21608/ejrsa.2020.51426.1108

S. Shaban, K. El-Adham, W. Khalil

引用次数: 0

Role of Asymmetric Dimethylarginine and Nitric Oxide in Type 2 Diabetes Mellitus and Its Cardiovascular Complications 不对称二甲基精氨酸和一氧化氮在2型糖尿病及其心血管并发症中的作用

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-10-23 DOI: 10.21608/ejrsa.2019.13784.1074

M. Alkady, I. Ibrahim

{"title":"Role of Asymmetric Dimethylarginine and Nitric Oxide in Type 2 Diabetes Mellitus and Its Cardiovascular Complications","authors":"M. Alkady, I. Ibrahim","doi":"10.21608/ejrsa.2019.13784.1074","DOIUrl":"https://doi.org/10.21608/ejrsa.2019.13784.1074","url":null,"abstract":"AN ENDOGENOUS inhibitor of nitric oxide synthase, asymmetric dimethylarginine (ADMA), is elevated in patients with type 2 diabetes mellitus (T2DM) and has been related to atherosclerotic disease. The study aims at investigating the status of ADMA and nitric oxide (NO) and their possible correlation inpatients with T2DM with and without cardiovascular complicationsin comparison to normalcontrols. Forty patients with T2DM and 20 age, sex and body mass index (BMI)‑matched healthy controls were included in the study. The studied individuals were divided into Group1: healthy controls (n= 20), Group 2: T2DM patients without cardiovascular complications (n= 20) and Group 3: T2DM patients with evidence of cardiovascular complications (n= 20). Serum ADMA levels were determined by enzyme linked Immunosorbent Assay (ELISA). Serum nitric oxide was measured as stable end product, nitrite. Insulin was measured by immunoradiometric method. Serum ADMA levels showed a significant elevation while serum NO levels were significantly reducedin diabetic patients groups in comparison to controls. Diabetic patients with vascular complications showed highly significant increase in ADMA levels and pronounced decrease in NO compared to those without complications. In the group of vascular complications, the ADMA level was positively correlated with postprandial serum glucose and HbA1c, but there was a negative correlation between ADMA levels and NO. ADMA and NO may serve as predictors for future cardiovascular events in T2DM patients. Further studies are required to establish the utility of decreasing ADMA levels or increasing NO in the management of T2DM patients.","PeriodicalId":11658,"journal":{"name":"Egyptian Journal of Radiation Sciences and Applications","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88968978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxidative Stress Parameters in Patients with Breast Cancer before and after Radiotherapy 乳腺癌患者放疗前后的氧化应激参数

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-10-21 DOI: 10.21608/ejrsa.2019.15164.1079

H. Youssef, H. Salem

{"title":"Oxidative Stress Parameters in Patients with Breast Cancer before and after Radiotherapy","authors":"H. Youssef, H. Salem","doi":"10.21608/ejrsa.2019.15164.1079","DOIUrl":"https://doi.org/10.21608/ejrsa.2019.15164.1079","url":null,"abstract":"REACTIVE oxygen species (ROS) are generated in response to endogenous or exogenous stimuli. Antioxidants defense system resists for balancing ROS-mediated injury; if oxidation exceeds the defense mechanisms, oxidative stress is generated. Oxidative stress may be involved in the development of breast cancer. Moreover, radiationtherapy (RT), used for the treatment of breast cancer, works by the production of reactive oxygen species at the site of radiation which leads to local oxidative stress. Studies which detect one or few oxidant and antioxidant markers failed to detect the overall oxidant/antioxidant status of the subjects. The authors aim at studying the impact of radiotherapy on the total oxidant status (TOS), total antioxidant status (TAS) with calculation of oxidative stress index (OSI), and measure the lipid peroxidation (MDA) in breast cancer patients.TAS, TOS, MDA and OSI in healthy and breast cancer groups are measured. In breast cancer group, all parameters were measuredbefore and after radiation therapy.In the breast cancer group, TOS, OSI and MDA levels have increased significantly (P<0.001) and the TAS level has decreased (P<0.001) in the breast cancer patients after radiotherapy than before radiotherapy. Breast cancer group TAS after RT reaches about forth its level measured inthe control group. Radiotherapy in breast cancer patients depletes the total antioxidants (TAS), increases total oxidative status (TOS), lipid peroxidation (MDA) and OSI. Breast cancer and its treatment modalities display the patients in a state of severe oxidative stress which requires the supplementation of antioxidants.","PeriodicalId":11658,"journal":{"name":"Egyptian Journal of Radiation Sciences and Applications","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73502784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Evaluation of C-Reactive Protein and CXCL16 in Acute Coronary Syndrome c -反应蛋白和CXCL16在急性冠脉综合征中的评价

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-10-08 DOI: 10.21608/ejrsa.2019.15472.1080

Neveen M. Nosseir, P. Abdel-Messeih, Ossama H. Bakheet, Samer Abdel Shafy

引用次数: 0

Assessment of Cerebral Collaterals in Acute Ischemic Stroke by CT Cerebral Angiography and Its Relation to the Functional Outcome 急性缺血性脑卒中CT脑血管造影评价脑侧络及其与功能预后的关系

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-09-04 DOI: 10.21608/ejrsa.2019.12994.1071

Dina Elessawi, Aymen Nasf, A. Shalash, D. Husseiny, Ebthal Bakry

引用次数: 1

Preparation and Quality Control on 113Sn, 125Sb and 60Co Adsorbed on ZrSiW: Volume and Planar Reference Source for -Detector Calibration ZrSiW吸附113Sn, 125Sb和60Co的制备及质量控制:探测器标定的体积和平面参考源

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-08-22 DOI: 10.21608/EJRSA.2019.12489.1069

H. El-Said, S. El-Deen, M. Aydia, M. El-Naggar, K. M. El-Azony

{"title":"Preparation and Quality Control on 113Sn, 125Sb and 60Co Adsorbed on ZrSiW: Volume and Planar Reference Source for -Detector Calibration","authors":"H. El-Said, S. El-Deen, M. Aydia, M. El-Naggar, K. M. El-Azony","doi":"10.21608/EJRSA.2019.12489.1069","DOIUrl":"https://doi.org/10.21608/EJRSA.2019.12489.1069","url":null,"abstract":"NEUTRON activation of tin metal and cobalt chloride targets for production of 113Sn and 125Sb and 60Co was carried out in Egypt’s Second Research Reactor (ETRR-2). The 113Sn, 125Sb and 60Co were loaded onto zirconium silicotungestate gel matrix from aqueous solution at pH 1 by the batch technique. The results obtained during the adsorption process of radionuclides were explained through the Visual MINTEQ program version 3. Then 1 and 0.1g of 113Sn. 125Sb and 60Co-ZrSiW were packed into the volume and planar sealed sources, made of Chinese Artelon, respectively. The radioactivity levels of 113Sn, 125Sb and 60Co were measured and found to be (2.96±0.26, 2.22±0.26, 0.74±0.074kBq) and (0.3±0.03, 026±0.03, 0.11±0.01kBq) for the volume and planar sealed source, respectively, on 27 June 2018. The efficiency curves for the two sealed sources were determined in the energy range 36-1332.5keV, which were measured at 5cm from the HPGe-detector to determine the radioactivity levels of unknown samples for the neutron activation method.","PeriodicalId":11658,"journal":{"name":"Egyptian Journal of Radiation Sciences and Applications","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75253996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant Capacity of Achillea millefolium L against Cytogenetic and Immunological Disorders in Irradiated Human Blood Cultures. 千叶阿喀琉叶对辐照人血培养细胞遗传学和免疫学紊乱的抗氧化能力。

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-08-07 DOI: 10.21608/EJRSA.2019.14648.1077

S. Montaser, Mahmoudi Mahmoud, S. Ibrahim

{"title":"Antioxidant Capacity of Achillea millefolium L against Cytogenetic and Immunological Disorders in Irradiated Human Blood Cultures.","authors":"S. Montaser, Mahmoudi Mahmoud, S. Ibrahim","doi":"10.21608/EJRSA.2019.14648.1077","DOIUrl":"https://doi.org/10.21608/EJRSA.2019.14648.1077","url":null,"abstract":"THE POSSIBLE antioxidant role of Achillea millefolium L. (ACM) extract was investigated against mutagenecity and immunological disorders in irradiated human blood cultures. Peripheral blood samples were collected from healthy human volunteers then incubated in the prepared cultures. The whole blood was exposed in vitro to 3 Gy of γ-ray and then the blood was cultured with mitogenic stimulation and ACM extract at different concentrations (100 & 200μg/ml). After 72hr of incubation, cytokinesis-block micronucleus analysis (CBMN) and immunological parameters: Interleukin-8 (IL-8), interleukin-18 (IL-18), cyclooxygenase-2 (COX-2) and tumor necrosis factor (TNF-α) were investigated. At each dose point, the treatment of the blood with ACM showed a significant decrease in the incidences of micronuclei (one, two and three micronuclei). Also, there are amelioration in the levels of IL-8, IL-18, Cox-2 and TNF-α. The maximum protection effect according to the selected parameters was observed at 200μg/ml of ACM extract. The presented data suggested that ACM may play important roles as antimutagenic and antinflammatory protectors against radiation exposure.","PeriodicalId":11658,"journal":{"name":"Egyptian Journal of Radiation Sciences and Applications","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78743140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Dose Audits of Patients Undergoing Some Common Radiographic Examinations in Selected Nigerian Hospitals 在选定的尼日利亚医院进行一些常见放射检查的病人的剂量审计

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-08-01 DOI: 10.21608/EJRSA.2019.5325.1053

L. Bamidele, Osahon. O. David

引用次数: 1

Reflex of oleandrin production and molecular changes on the Nerium oleander L. cell suspension culture under UV-A radiation stress effect. UV-A辐射胁迫下夹竹桃细胞悬浮培养中夹竹桃素产生及分子变化的反射

Egyptian Journal of Radiation Sciences and Applications Pub Date : 2019-08-01 DOI: 10.21608/EJRSA.2019.7166.1062

I. Salama, M. K. A. el-Megid

{"title":"Reflex of oleandrin production and molecular changes on the Nerium oleander L. cell suspension culture under UV-A radiation stress effect.","authors":"I. Salama, M. K. A. el-Megid","doi":"10.21608/EJRSA.2019.7166.1062","DOIUrl":"https://doi.org/10.21608/EJRSA.2019.7166.1062","url":null,"abstract":"THE AIM of this study is to determine the oleandrin concentrations in the Nerium oleander cell suspension culture after being exposed to UV-A (365nm), at different time intervals (0 controls, 5, 10, 15, 20, 25, 30, 35, 40, 45 and 50min). The results showed that the maximum time limits for carrying N. oleander cells suspension culture to exposure of UV-A is 30min.The present study also aims at investigating changes of the protein bands, peroxidase isozyme and oleandrin concentration at the same condition. Oleandrin was separated and quantified by HPLC. The investigation of protein changes was conducted using SDS PAGE electrophoresis techniques. The results revealed that the changes of the protein bands depend on different time intervals of exposure to A-UV radiation. Thus, the changes of the oleandrin production were consequent to gene expression changes. Peroxidase isozyme analysis, showed that exposure to UV-A for the 5, 15 and 20min had a clear impact on the peroxidase isozyme, but the greatest impact was in the sample exposed to UV-A for a period of 15 minutes (0.093±0.01) μg/ml, the same sample showed the highest concentration of oleandrin compared to the control (0.022±0.001) μg/ml. However, the other samples were less affected by the exposure to UV-A.","PeriodicalId":11658,"journal":{"name":"Egyptian Journal of Radiation Sciences and Applications","volume":"2004 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78866031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5