Huan Zhao, Juciliane Haidamak, Eva Noskova, Vladislav Ilik, Barbora Pafčo, Rebecca Ford, Geraldine Masiria, Tobias Maure, Nichola Kotale, William Pomat, Catherine Gordon, Severine Navarro, Paul F. Horwood, Constantin Constantinoiu, Andrew R. Greenhill, Richard S. Bradbury
{"title":"Insights into Infant Strongyloidiasis, Papua New Guinea","authors":"Huan Zhao, Juciliane Haidamak, Eva Noskova, Vladislav Ilik, Barbora Pafčo, Rebecca Ford, Geraldine Masiria, Tobias Maure, Nichola Kotale, William Pomat, Catherine Gordon, Severine Navarro, Paul F. Horwood, Constantin Constantinoiu, Andrew R. Greenhill, Richard S. Bradbury","doi":"10.3201/eid3109.241923","DOIUrl":"https://doi.org/10.3201/eid3109.241923","url":null,"abstract":"<p>The human-infecting parasite <em>Strongyloides fuelleborni</em> subspecies <em>kellyi</em> has been reported from the island of New Guinea. We analyzed fecal DNA extracts (n = 164) from 19 infants in Papua New Guinea by using <em>Strongyloides</em> real-time PCR and undertook metabarcoding of <em>cox1</em> and 18S rRNA hypervariable regions I and IV loci. Eight infants were infected with <em>Strongyloides</em> spp.; 7 were infected with <em>S. fuelleborni</em> subsp. <em>fuelleborni</em> and 1 with a <em>Strongyloides</em> sp. previously misattributed to <em>S. fuelleborni</em> subsp. <em>kellyi</em>. Phylogenetic and haplotyping analyses indicated <em>S. fuelleborni</em> in Papua New Guinea belongs to the Indochina subclade of <em>S. fuelleborni</em> subsp. <em>fuelleborni</em> and is not a unique subspecies. We report molecular evidence of <em>S. fuelleborni</em> subsp. <em>fuelleborni</em> infection in humans in the Pacific. Our findings also demonstrate the potential co-existence of an undescribed human-infecting <em>Strongyloides</em> sp. on the island of New Guinea, indicating a need for renewed clinical and epidemiologic investigations into infant strongyloidiasis.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"37 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Modrý, Edmund K. Hainisch, Hans-Peter Fuehrer, Edwin Kniha, Maria Sophia Unterköfler, Jovana Sádlová, Petr Jahn, Kristína Řeháková, Kamil Sedlák, Jan Votýpka
{"title":"Emergence of Autochthonous Leishmania (Mundinia) martiniquensis Infections in Horses, Czech Republic and Austria, 2019–2023","authors":"David Modrý, Edmund K. Hainisch, Hans-Peter Fuehrer, Edwin Kniha, Maria Sophia Unterköfler, Jovana Sádlová, Petr Jahn, Kristína Řeháková, Kamil Sedlák, Jan Votýpka","doi":"10.3201/eid3109.250254","DOIUrl":"https://doi.org/10.3201/eid3109.250254","url":null,"abstract":"<p>We report 4 cases of equine cutaneous leishmaniasis caused by <em>Leishmania martiniquensis</em> in Czech Republic and Austria, outside the known endemic range of leishmaniases. The parasite should be considered as a potential cause of cutaneous lesions in horses; the risk for zoonotic transmission to immunocompromised humans is anticipated throughout central Europe.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"26 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justine De Langhe, Jo Sourbron, Robbe Van Herreweghe, Marjan van Esbroeck, Koen Vercauteren, Tessa de Block, Jasmine Coppens, Daan Jansen, Dorien Van den Bossche, Veerle Staelens, Sarah De Schryver, Jos Van Acker
{"title":"Pediatric Case Report and Overview of Autochthonous Tick-Borne Encephalitis, Belgium","authors":"Justine De Langhe, Jo Sourbron, Robbe Van Herreweghe, Marjan van Esbroeck, Koen Vercauteren, Tessa de Block, Jasmine Coppens, Daan Jansen, Dorien Van den Bossche, Veerle Staelens, Sarah De Schryver, Jos Van Acker","doi":"10.3201/eid3109.250093","DOIUrl":"https://doi.org/10.3201/eid3109.250093","url":null,"abstract":"<p>Prevalence of tick-borne encephalitis (TBE) is increasing in much of Europe. In May 2024, an autochthonous pediatric case of TBE was diagnosed in a 6-year-old girl in Belgium. Clinicians should recognize the symptoms and signs of TBE infections and consider this disease in patients with unexplained neurologic symptoms, regardless of travel history.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"13 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144901738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Barr, Sarah Caruso, Sarah J. Edwards, Shawn Todd, Ina Smith, Mary Tachedjian, Gary Crameri, Lin-Fa Wang, Glenn A. Marsh
{"title":"Novel Henipavirus, Salt Gully Virus, Isolated from Pteropid Bats, Australia","authors":"Jennifer Barr, Sarah Caruso, Sarah J. Edwards, Shawn Todd, Ina Smith, Mary Tachedjian, Gary Crameri, Lin-Fa Wang, Glenn A. Marsh","doi":"10.3201/eid3109.250470","DOIUrl":"https://doi.org/10.3201/eid3109.250470","url":null,"abstract":"<p>We describe isolation and characterization of a novel henipavirus, designated Salt Gully virus, from the urine of pteropid bats in Australia. We noted the virus to be most closely related to Angavokely virus, not reliant on ephrin receptors for cell entry, and of unknown risk for human disease.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"27 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tshokey Tshokey, John Stenos, Mythili Tadepalli, Chelsea Nguyen, Stephen R. Graves
{"title":"Genetic Characterization of Orientia tsutsugamushi, Bhutan, 2015","authors":"Tshokey Tshokey, John Stenos, Mythili Tadepalli, Chelsea Nguyen, Stephen R. Graves","doi":"10.3201/eid3109.241763","DOIUrl":"https://doi.org/10.3201/eid3109.241763","url":null,"abstract":"<p>We performed molecular characterization of <em>Orientia tsutsugamushi</em> on DNA sequences from 5 patients from Bhutan with scrub typhus. In the 56 kDa gene, all isolates aligned with those from other Asia countries, including Nepal, India, Thailand, and Taiwan. High serum IgM titers correlated with PCR positivity in acutely ill patients.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"7 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kalev Nõupuu, Maare Mõtsküla, Riina Pulges, Mikk Pauklin, Urmas Saarma
{"title":"Characterization of Emerging Human Dirofilaria repens Infections, Estonia, 2023","authors":"Kalev Nõupuu, Maare Mõtsküla, Riina Pulges, Mikk Pauklin, Urmas Saarma","doi":"10.3201/eid3109.241890","DOIUrl":"https://doi.org/10.3201/eid3109.241890","url":null,"abstract":"<p>Mosquitoborne diseases are a growing threat to public health worldwide. Human dirofilariasis, caused by the nematode <em>Dirofilaria repens</em> and transmitted by mosquitoes from various genera, has recently expanded into new areas of Europe. In this article, we report molecularly confirmed autochthonous human <em>D. repens</em> infections in Estonia.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"12 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olga P. Zelya, Irina V. Kukina, Ludmila S. Karan, Elena A. Krasilovskaya, Vadim V. Garin
{"title":"Human Babesiosis Caused by Babesia venatorum, Russia, 2024","authors":"Olga P. Zelya, Irina V. Kukina, Ludmila S. Karan, Elena A. Krasilovskaya, Vadim V. Garin","doi":"10.3201/eid3109.250319","DOIUrl":"https://doi.org/10.3201/eid3109.250319","url":null,"abstract":"<p>We report a case of acute babesiosis in a splenectomized 63-year-old man in Siberia, Russia. We confirmed the causative agent, <em>Babesia venatorum</em>, by PCR. Our study demonstrated a change in the structure of the parasite population, from single parasite invasion of erythrocytes to multioccupancy, without an increase in parasitemia level.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"20 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Hannah Gould, Sarah J. Willis, Christopher G. Prener, Stephanie A. Duench, Holly Yu, Luis Jodar, Jennifer C. Moïsi, James H. Stark
{"title":"Differences in Lyme Disease Diagnosis among Medicaid and Medicare Beneficiaries, United States, 2016–2021","authors":"L. Hannah Gould, Sarah J. Willis, Christopher G. Prener, Stephanie A. Duench, Holly Yu, Luis Jodar, Jennifer C. Moïsi, James H. Stark","doi":"10.3201/eid3109.241653","DOIUrl":"https://doi.org/10.3201/eid3109.241653","url":null,"abstract":"<p>Lyme disease is the most common vectorborne disease in the United States. Evidence suggests that persons from racial and ethnic minority groups experience more severe disease. We used a claims-based algorithm on data from 16 jurisdictions with high Lyme disease incidence to identify cases among 4 populations: Medicaid beneficiaries <span><</span>18 and <span>></span>19 years of age, and Medicare fee-for-service beneficiaries <65 and <span>></span>65 years of age. We calculated the prevalence of disseminated disease, hospitalization, and other clinical and epidemiologic parameters by race and ethnicity. We found that non-White persons were more likely than White persons to be female, hospitalized at diagnosis, diagnosed outside of primary care, diagnosed outside of the peak months for Lyme disease transmission, and have disseminated disease. Those data illustrate differences in Lyme disease by race and ethnicity and suggest possible differences across other sociodemographic characteristics. Additional prevention methods are needed to reduce differences in Lyme disease recognition and severity.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"15 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144899382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Melchior do Prado, Bram Spruijtenburg, Emanuel Razzolini, Luciana Chiyo, Carlos Santi, Caroline Amaral Martins, Gabriela Santacruz, Nancy Segovia, José Pereira Brunelli, Regielly Caroline Raimundo Cognialli, Jacques F. Meis, Vânia Aparecida Vicente, Theun de Groot, Eelco F.J. Meijer, Flávio Queiroz-Telles
{"title":"Sporothrix brasiliensis Treatment Failure without Initial Elevated Itraconazole MICs in Felids at Border of Brazil","authors":"Carolina Melchior do Prado, Bram Spruijtenburg, Emanuel Razzolini, Luciana Chiyo, Carlos Santi, Caroline Amaral Martins, Gabriela Santacruz, Nancy Segovia, José Pereira Brunelli, Regielly Caroline Raimundo Cognialli, Jacques F. Meis, Vânia Aparecida Vicente, Theun de Groot, Eelco F.J. Meijer, Flávio Queiroz-Telles","doi":"10.3201/eid3109.250156","DOIUrl":"https://doi.org/10.3201/eid3109.250156","url":null,"abstract":"<p>Cat-transmitted sporotrichosis caused by <em>Sporothrix brasiliensis</em> is an emerging zoonosis in Latin America. Because treatment of feline sporotrichosis is often not effective, we sought to determine whether treatment failure results from <em>S. brasiliensis</em> strains that have existing elevated MICs for itraconazole, the primary treatment for this disease. During 2021–2023 at the triple border region of Brazil, Paraguay, and Argentina, 108 <em>S. brasiliensis</em> strains were isolated from felines before antifungal treatment. The main clinical manifestation was cutaneous disseminated sporotrichosis (61%), which was the only form resulting in sporotrichosis-induced deaths (61%). We conducted antifungal susceptibility testing for 9 antifungal compounds, evaluating for both mycelial and yeast phases. MIC levels were low for most antifungal agents but were higher in the mycelial phase than in the yeast phase, especially for voriconazole and isavuconazole. We conclude that the varying clinical manifestations of sporotrichosis and large differences in mortality rates were not caused by elevated itraconazole MICs.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"36 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144901743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}