Alexandria B. Boehm, Marlene K. Wolfe, Amanda L. Bidwell, Bradley J. White, Bridgette Shelden, Dorothea Duong
{"title":"Detection of Monkeypox Virus Clade Ib in Wastewater Solids at Wastewater Treatment Plants, United States","authors":"Alexandria B. Boehm, Marlene K. Wolfe, Amanda L. Bidwell, Bradley J. White, Bridgette Shelden, Dorothea Duong","doi":"10.3201/eid3110.250270","DOIUrl":"https://doi.org/10.3201/eid3110.250270","url":null,"abstract":"<p>We used a sensitive and specific PCR to detect monkeypox virus clade Ib DNA from >3,000 wastewater samples collected prospectively across the United States. Monkeypox virus clade Ib DNA was detected in 1 sample from a location with a confirmed case; it was not detected in locations with no confirmed cases.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"35 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145068036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hilal Samut, Damaris V. Mendez-Vallellanes, Hannah Hoyt, Samantha E. Wirth, Lisa Mingle, Brian D. Sauders, Gregory A. Deiulio, Alyssa W. Dickey, Maria L. Ishida, William J. Wolfgang, Martin Wiedmann, Renato H. Orsi
{"title":"Retrospective Analysis of Historical Listeria monocytogenes Clinical Isolates, New York, USA, 2000–2021","authors":"Hilal Samut, Damaris V. Mendez-Vallellanes, Hannah Hoyt, Samantha E. Wirth, Lisa Mingle, Brian D. Sauders, Gregory A. Deiulio, Alyssa W. Dickey, Maria L. Ishida, William J. Wolfgang, Martin Wiedmann, Renato H. Orsi","doi":"10.3201/eid3110.241876","DOIUrl":"https://doi.org/10.3201/eid3110.241876","url":null,"abstract":"<p>We used whole-genome sequencing data to investigate historical <em>Listeria monocytogenes</em> clinical (n = 1,046) and nonclinical (n = 1,325) isolates from New York, USA. Applying a threshold of <span><</span>20 single-nucleotide polymorphism differences for single-linkage clustering, 321 clinical isolates clustered into 85 clusters ranging from 2–33 isolates per cluster. Fourteen clusters included isolates with outbreak codes (4 clusters with New York codes and 10 with multistate codes). Three New York outbreak codes were assigned to isolates that were genetically highly related and from cases <2 months apart. Fifteen clusters included isolates that were obtained >10 years apart; 33 clusters included isolates from the same or contiguous counties. Seventeen clusters included food and environmental isolates highly related to clinical isolates. These findings suggest that some listeriosis clusters can be local and span a long period, demonstrating the importance of investigating small, localized listeriosis cases with closely related isolates, even over long timeframes.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"24 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabine Obagi, Lauren E. Murphy, Aleksi J. Hendricks, Kim Hiatt, Allen Miraflor, Robert E. Cashman, Mohammad Fazel
{"title":"Cutaneous Coccidioidomycosis Mimicking Rosacea in Immunosuppressed Patient, Arizona, USA, 2024","authors":"Sabine Obagi, Lauren E. Murphy, Aleksi J. Hendricks, Kim Hiatt, Allen Miraflor, Robert E. Cashman, Mohammad Fazel","doi":"10.3201/eid3110.250010","DOIUrl":"https://doi.org/10.3201/eid3110.250010","url":null,"abstract":"<p>An immunocompromised patient in Arizona, USA, experienced cutaneous coccidioidomycosis mimicking rosacea-like dermatitis; she was receiving vandetanib therapy. Histopathology confirmed the diagnosis despite inconclusive serologic results. Lesions resolved with fluconazole treatment, but blue-gray hyperpigmentation persisted, likely linked to vandetanib. This case highlights diagnostic challenges in endemic fungal infections and rare drug-associated hyperpigmentation.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"300 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samuel Schildhauer,Kayla Saadeh,Robert E Snyder,Eric C Tang,Eric Chapman,Deanna A Sykes,Philip Peters,Kathleen Jacobson,Jessica Watson,Kelly A Johnson
{"title":"Prolonged Monkeypox Virus Infections, California, USA, May 2022-August 2024.","authors":"Samuel Schildhauer,Kayla Saadeh,Robert E Snyder,Eric C Tang,Eric Chapman,Deanna A Sykes,Philip Peters,Kathleen Jacobson,Jessica Watson,Kelly A Johnson","doi":"10.3201/eid3110.250507","DOIUrl":"https://doi.org/10.3201/eid3110.250507","url":null,"abstract":"Monkeypox virus (MPXV) infection typically lasts 14-28 days. Prolonged MPXV infection, in which symptoms or test positivity last >28 days, has been documented but not fully characterized. We used the California Department of Public Health (California, USA) mpox registry to compare prolonged (>28 days) and nonprolonged (<28 days) mpox cases by demographics, HIV status, and JYNNEOS vaccination status. Of 6,469 cases, 82 (1.3%) were prolonged. Persons with prolonged MPXV infections were more likely to be Black or African American (prolonged, 20.7%, vs. nonprolonged, 11.6%) and to have HIV (prolonged, 61.0%, vs. nonprolonged, 39.9%). Among persons with HIV, prolonged infections were more likely among those with lower (<200) CD4 counts (prolonged, 10.0%, vs. nonprolonged, 3.9%) or not engaged in HIV care (prolonged, 46.0%, vs. nonprolonged, 18.1%). No prolonged infections occurred in persons who received 2 JYNNEOS vaccine doses. Groups disproportionately affected by prolonged mpox should be prioritized for mpox vaccine education and outreach.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"33 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145035647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gehan Devendra, Madeleine Chai, Eyrica Sumida, Richard Chen, Maan Gozun, Dominic Chow, F. DeWolfe Miller
{"title":"Differences in COVID-19 Fatality Rates among Ethnic Groups, Hawaii, USA, 2020–2022","authors":"Gehan Devendra, Madeleine Chai, Eyrica Sumida, Richard Chen, Maan Gozun, Dominic Chow, F. DeWolfe Miller","doi":"10.3201/eid3110.241070","DOIUrl":"https://doi.org/10.3201/eid3110.241070","url":null,"abstract":"<p>Asian American, Native Hawaiian, and Pacific Islander populations have been underrepresented in research on COVID-19 outcomes. We conducted a cross-sectional study of 5,494 electronic medical records of patients in a large tertiary care health system in the ethnically diverse state of Hawaii, USA. We compared fatality rates for hospitalized patients on the basis of race or ethnicity, age, vaccination status, and sequential organ failure assessment (SOFA) score at admission. Fatality rates varied between racial and ethnic groups but were associated with increasing age across all groups. Fatality rates were closely associated with increasing SOFA score and were inversely associated with the number of COVID-19 vaccinations received. We found that Asian and Pacific Islander groups experienced higher rates of in-hospital death and that death was strongly associated with increased age and SOFA score and with <span><</span>1 COVID-19 vaccination. Clinicians should be aware of these outcomes when treating COVID-19 patients from these ethnic groups. </p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"32 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145043186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sadia Isfat Ara Rahman, Md Golam Firoj, Se Eun Park, Farhana Khanam, Suneth Agampodi, Kassa Haile, Edilawit Mesfin, Faisal Ahmmed, Md Taufiqul Islam, Ashraful Islam Khan, Fahima Chowdhury, Afroza Akter, Martin Bundi Mwebia, Justin Im, Natasha Y. Rickett, Cecilia Kathure Mbae, Asma Binte Aziz, Beatrice Ongadi, Moses Mwangi, Benjamin Ngugi, Meseret Gebre Behute, Kelvin Kering, Suman Kanungo, Xinxue Liu, Deok Ryun Kim, Andrew J. Pollard, K Zaman, Samuel Kariuki, Firdausi Qadri, John D. Clemens
{"title":"Comparative Epidemiology of Salmonella Paratyphi A and Salmonella Typhi Causing Enteric Fever, Bangladesh, 2018–2020","authors":"Sadia Isfat Ara Rahman, Md Golam Firoj, Se Eun Park, Farhana Khanam, Suneth Agampodi, Kassa Haile, Edilawit Mesfin, Faisal Ahmmed, Md Taufiqul Islam, Ashraful Islam Khan, Fahima Chowdhury, Afroza Akter, Martin Bundi Mwebia, Justin Im, Natasha Y. Rickett, Cecilia Kathure Mbae, Asma Binte Aziz, Beatrice Ongadi, Moses Mwangi, Benjamin Ngugi, Meseret Gebre Behute, Kelvin Kering, Suman Kanungo, Xinxue Liu, Deok Ryun Kim, Andrew J. Pollard, K Zaman, Samuel Kariuki, Firdausi Qadri, John D. Clemens","doi":"10.3201/eid3110.241601","DOIUrl":"https://doi.org/10.3201/eid3110.241601","url":null,"abstract":"<p>Enteric fever remains a public health challenge. We analyzed data from a cluster-randomized Vi-tetanus toxoid conjugate vaccine trial to compare the epidemiology between <em>Salmonella enterica</em> serovars Paratyphi A, which causes paratyphoid fever, and Typhi, which causes typhoid fever. The overall incidence rate of paratyphoid fever was 27 (95% CI 23–32)/100,000 person-years (PY) and of typhoid fever was 216 (95% CI 198–236)/100,000 PY. We observed the highest incidence for both diseases in children 2–4 years of age: 72 (95% CI 41–117)/100,000 PY for paratyphoid and 887 (95% CI 715–1,088)/100,000 PY for typhoid. Lack of private toilets and safe drinking water were associated with both diseases. Prevalence of multidrug resistance was significantly higher in <em>Salmonella</em> Typhi (20.2%) than in <em>Salmonella</em> Paratyphi A (0.8%) (p<0.001). Our data suggest that integrated control measures targeting water, sanitation, and hygiene measures and bivalent vaccine targeting both pathogens are promising strategies to control both diseases.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"131 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Esperón, Bárbara Martín-Maldonado, Irene Iglesias, Elena Neves, Eleonora Seri, Paula García-Sanchez, Ángel Morillas-Mingorance, Ana Méndez-Echevarría
{"title":"Bat-Associated Hemotropic Mycoplasmas in Immunosuppressed Children, Spain, 2024","authors":"Fernando Esperón, Bárbara Martín-Maldonado, Irene Iglesias, Elena Neves, Eleonora Seri, Paula García-Sanchez, Ángel Morillas-Mingorance, Ana Méndez-Echevarría","doi":"10.3201/eid3110.250862","DOIUrl":"https://doi.org/10.3201/eid3110.250862","url":null,"abstract":"<p>We report the detection of hemotropic mycoplasmas in 4 immunosuppressed pediatric patients in Spain: 2 solid organ transplant recipients, 1 hematopoietic stem cell transplant recipient, and 1 cancer patient. Sequences were 100% identical to a strain previously identified in <em>Miniopterus schreibersii</em> bats, which raises concerns about unnoticed zoonotic transmission.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"17 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145017622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Barbara Šoba, Sandra Kolar, Albin Gačnik, Manca Radež, Timotej Petrijan, Jana Rejc Marko
{"title":"Subarachnoid Neurocysticercosis Caused by Larval-Stage Taenia crassiceps Tapeworm, Slovenia.","authors":"Barbara Šoba, Sandra Kolar, Albin Gačnik, Manca Radež, Timotej Petrijan, Jana Rejc Marko","doi":"10.3201/eid3109.250014","DOIUrl":"10.3201/eid3109.250014","url":null,"abstract":"<p><p>We present a case of subarachnoid neurocysticercosis caused by Taenia crassiceps in an elderly woman in Slovenia with no underlying disease or immunosuppressive treatment. The parasite was identified by 12S rDNA PCR and sequencing. Despite prolonged therapy with albendazole and praziquantel, the disease recurred after treatment was discontinued.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 9","pages":"1865-1868"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inês Lopes, Joana Dias, Edvaldo Das Neves, Maria Morais, Ana Santos-Reis, Ana M Garcia, Luis Varandas, Dinora Lopes
{"title":"Imported Malaria and Congenital Acquisition in Infant, Portugal, 2024.","authors":"Inês Lopes, Joana Dias, Edvaldo Das Neves, Maria Morais, Ana Santos-Reis, Ana M Garcia, Luis Varandas, Dinora Lopes","doi":"10.3201/eid3109.250536","DOIUrl":"10.3201/eid3109.250536","url":null,"abstract":"<p><p>Plasmodium falciparum infection was diagnosed in a 3-month-old baby in Portugal by optical microscopy. The mother had had malaria in Angola 13 months earlier, before she emigrated to Portugal. She remained asymptomatic throughout and after pregnancy. We confirmed the diagnosis of an imported malaria case and congenital transmission using molecular techniques.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 9","pages":"1843-1846"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skyler Brennan, Julie M Thompson, Christopher A Gulvik, Taylor K Paisie, Mindy Glass Elrod, Jay E Gee, Caroline A Schrodt, Katherine M DeBord, Brian T Richardson, Cherie Drenzek, William A Bower, Alex R Hoffmaster, Zachary P Weiner, Caitlin M Cossaboom, Julie Gabel
{"title":"Related Melioidosis Cases with Unknown Exposure Source, Georgia, USA, 1983-2024.","authors":"Skyler Brennan, Julie M Thompson, Christopher A Gulvik, Taylor K Paisie, Mindy Glass Elrod, Jay E Gee, Caroline A Schrodt, Katherine M DeBord, Brian T Richardson, Cherie Drenzek, William A Bower, Alex R Hoffmaster, Zachary P Weiner, Caitlin M Cossaboom, Julie Gabel","doi":"10.3201/eid3109.250804","DOIUrl":"10.3201/eid3109.250804","url":null,"abstract":"<p><p>We identified 4 cases of presumptive autochthonous melioidosis during 1983-2024 in Georgia, USA. Epidemiologic investigation identified no recent international travel before illness; all cases were geographically linked, and 3 patients became ill after a severe weather event. Bioinformatic analyses revealed Burkholderia pseudomallei genome sequences were highly related, suggesting a shared exposure.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 9","pages":"1802-1806"},"PeriodicalIF":6.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12407204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}