Mariaelisa Carbonara, Simona Gabrielli, Alessia Ricci, Roberta Iatta, Riccardo Paolo Lia, Maria Virginia Tomassi, Andrea Mariano, Jairo Alfonso Mendoza-Roldan, Domenico Otranto
{"title":"Rapid Subcutaneous Migration of Dirofilaria repens Nematode in Facial Tissue, Italy","authors":"Mariaelisa Carbonara, Simona Gabrielli, Alessia Ricci, Roberta Iatta, Riccardo Paolo Lia, Maria Virginia Tomassi, Andrea Mariano, Jairo Alfonso Mendoza-Roldan, Domenico Otranto","doi":"10.3201/eid3106.241915","DOIUrl":"https://doi.org/10.3201/eid3106.241915","url":null,"abstract":"<p>We report a <em>Dirofilaria repens</em> nematode infection in a woman in Italy who sought care for a fast-creeping lesion within her subcutaneous facial tissue. Dirofilariosis should be included in differential diagnosis of subcutaneous nodules or creeping lesions. This case highlights the need for controlling canine dirofilarioses to mitigate zoonotic risk.</p>\u0000<p></p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"19 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiara Sepulcri, Rachele Pincino, Federico Baldi, Giovanni Cenderello, Stefania Zanet, Daniela Boccolini, Anna Rosa Sannella, Mariangela L’Episcopia, Carlo Severini, Matteo Bassetti, Chiara Dentone, Ezio Ferroglio
{"title":"Three Cases of Human Babesiosis, Italy, 2017–2020","authors":"Chiara Sepulcri, Rachele Pincino, Federico Baldi, Giovanni Cenderello, Stefania Zanet, Daniela Boccolini, Anna Rosa Sannella, Mariangela L’Episcopia, Carlo Severini, Matteo Bassetti, Chiara Dentone, Ezio Ferroglio","doi":"10.3201/eid3106.241776","DOIUrl":"https://doi.org/10.3201/eid3106.241776","url":null,"abstract":"<p>We report 3 cases of babesiosis in Italy caused by <em>Babesia</em> species that are rarely reported in humans. The circulation of <em>Babesia</em> spp. among vectors, animals, and humans might be more common than previously thought, and babesiosis might be an underdiagnosed and emerging disease in Italy and Europe.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"94 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan O. Rosas, Alejandra Benitez, James A. McKinnell, Reena Shah, Michael Waters, Bradley D. Hunter, Robert Jeanfreau, Larry Tsai, Margaret Neighbors, Ben Trzaskoma, Rita de Cassia Castro, Fang Cai
{"title":"Long-Term Clinical Outcomes of Adults Hospitalized for COVID-19 Pneumonia","authors":"Ivan O. Rosas, Alejandra Benitez, James A. McKinnell, Reena Shah, Michael Waters, Bradley D. Hunter, Robert Jeanfreau, Larry Tsai, Margaret Neighbors, Ben Trzaskoma, Rita de Cassia Castro, Fang Cai","doi":"10.3201/eid3106.241097","DOIUrl":"https://doi.org/10.3201/eid3106.241097","url":null,"abstract":"<p>We conducted a multicenter, observational, 12-month follow-up study to identify the extended health burden of severe COVID-19 pneumonia by characterizing long-term sequelae of acute infection in participants previously enrolled in clinical trials for severe COVID-19 pneumonia requiring hospitalization. Overall, 134 (77.5%) of 173 participants completed the study. At 12 months, 51 (29.5%) participants reported cough, 60 (34.7%) reported dyspnea, 56 (32.4%) had residual lung texture abnormalities on high-resolution computed tomography scans, 26 (15.0%) had impaired forced vital capacity, 52 (30.1%) had cognitive impairment, and 77 (44.5%) reported fatigue. Disease severity during acute infection and age were associated with persistent lung abnormalities; history of hypertension was associated with higher prevalence of fatigue and more frequent dyspnea and cough; and age and obesity were associated with long-term cognitive impairment. Our findings underscore the long-term health burden of severe COVID-19 pneumonia, reinforcing the importance of regular monitoring in older persons and those with underlying illnesses.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"148 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariangela L’Episcopia, Albadawi A. Talha, Bakri Y.M. Nour, Ibrahim Mohamed Ahmed Sana, Emmanuelle Caspar, Lucas Thiebaut, Lucien Platon, Buze Chala, Laurence Ma, Lemu Golassa, Edvige Perrotti, Carlo Severini, Didier Menard
{"title":"High Prevalence of Artemisinin-Resistant Plasmodium falciparum, Southeastern Sudan","authors":"Mariangela L’Episcopia, Albadawi A. Talha, Bakri Y.M. Nour, Ibrahim Mohamed Ahmed Sana, Emmanuelle Caspar, Lucas Thiebaut, Lucien Platon, Buze Chala, Laurence Ma, Lemu Golassa, Edvige Perrotti, Carlo Severini, Didier Menard","doi":"10.3201/eid3106.241810","DOIUrl":"https://doi.org/10.3201/eid3106.241810","url":null,"abstract":"<p>We conducted a hospital-based cross-sectional study of <em>Plasmodium falciparum</em> in 2017 in southeastern Sudan. Among 257 <em>P. falciparum</em> samples, we found 22% harbored the <em>pfkelch13</em> R622I mutation and 10.7% showed <em>hrp2/3</em> gene deletions. Our findings highlight the urgent need for enhanced surveillance of drug- and diagnostic-resistant parasites in the Horn of Africa.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"63 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lucious Chabuka, Wonderful T. Choga, Carla N. Mavian, Monika Moir, Christian Morgenstern, Houriiyah Tegaly, Abhinav Sharma, Eduan Wilkinson, Yeshnee Naidoo, Rhys Inward, Samir Bhatt, G.R. WilliamWint, Kamran Khan, Isaac I. Bogoch, Moritz U.G. Kraemer, José Lourenço, Cheryl Baxter, Massimiliano Tagliamonte, Marco Salemi, Richard J. Lessells, Collins Mitambo, Ronald Chitatanga, Joseph Bitilinyu-Bango, Mabvuto Chiwaula, Yollamu Chavula, Mphatso Bukhu, Happy Manda, Moses Chitenje, Innocent Malolo, Alex Mwanyongo, Bernard Mvula, Mirrium Nyenje, Tulio de Oliveira, Mathew Kagoli
{"title":"Genomic Surveillance of Climate-Amplified Cholera Outbreak, Malawi, 2022–2023","authors":"Lucious Chabuka, Wonderful T. Choga, Carla N. Mavian, Monika Moir, Christian Morgenstern, Houriiyah Tegaly, Abhinav Sharma, Eduan Wilkinson, Yeshnee Naidoo, Rhys Inward, Samir Bhatt, G.R. WilliamWint, Kamran Khan, Isaac I. Bogoch, Moritz U.G. Kraemer, José Lourenço, Cheryl Baxter, Massimiliano Tagliamonte, Marco Salemi, Richard J. Lessells, Collins Mitambo, Ronald Chitatanga, Joseph Bitilinyu-Bango, Mabvuto Chiwaula, Yollamu Chavula, Mphatso Bukhu, Happy Manda, Moses Chitenje, Innocent Malolo, Alex Mwanyongo, Bernard Mvula, Mirrium Nyenje, Tulio de Oliveira, Mathew Kagoli","doi":"10.3201/eid3106.240930","DOIUrl":"https://doi.org/10.3201/eid3106.240930","url":null,"abstract":"<p>In the aftermath of 2 extreme weather events in 2022, Malawi experienced a severe cholera outbreak; 59,325 cases and 1,774 deaths were reported by March 31, 2024. We generated 49 <em>Vibrio cholerae</em> full genomes from isolates collected during December 2022–March 2023. Phylogenetic and phylogeographic methods confirmed that the Malawi outbreak strains originated from Pakistan’s 2022 cholera outbreak. That finding aligns with substantial travel between the 2 countries. The estimated most recent ancestor of this lineage was from June–August 2022, coinciding with Pakistan’s floods and cholera surge. Our analysis indicates that major floods in Malawi contributed to the outbreak; reproduction numbers peaked in late December 2022. We conclude that extreme weather events and humanitarian crises in Malawi created conditions conducive to the spread of cholera, and population displacement likely contributed to transmission to susceptible populations in areas relatively unaffected by cholera for more than a decade.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"25 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Villamizar Gomez, Sandra Patricia Pérez Español, Marco Alexander Figueroa Caicedo, Andrea Camila Márquez Nossa
{"title":"Aedes aegypti Mosquito Detection at Bus Stations, Bogota, Colombia, 2023–2024","authors":"Andrea Villamizar Gomez, Sandra Patricia Pérez Español, Marco Alexander Figueroa Caicedo, Andrea Camila Márquez Nossa","doi":"10.3201/eid3106.241052","DOIUrl":"https://doi.org/10.3201/eid3106.241052","url":null,"abstract":"<p>We monitored mosquitoes in 3 bus stations in Bogota, Colombia, located at 2,625 m above sea level. During December 2023–January 2024, we collected 27 larvae and 1 adult female <em>Aedes aegypti</em> mosquitoes at 1 station. Detection of <em>Ae. aegypti</em> mosquitoes in Bogota is a call to continue monitoring mosquitoes at stations.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"135 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Force of Infection Model for Estimating Time to Dengue Virus Seropositivity among Expatriate Populations, Thailand","authors":"Erica Rapheal, Amornphat Kitro, Hisham Imad, Marco Hamins-Peurtolas, Jutarmas Olanwijitwong, Lapakorn Chatapat, Taweewun Hunsawong, Kathryn Anderson, Watcharapong Piyaphanee","doi":"10.3201/eid3106.241686","DOIUrl":"https://doi.org/10.3201/eid3106.241686","url":null,"abstract":"<p>Dengue is a major cause of illness among local populations and travelers in dengue-endemic areas, particularly those who stay for an extended period. However, little is known about dengue risk among expatriates and other long-term travelers. We used catalytic models of force of infection to estimate time to 60% dengue virus (DENV) seropositivity for a cross-section of expatriates living in Bangkok and Pattaya, Thailand. Our model adjusted for daily time spent outside, years not exposed to DENV, sex, living environment, and use of mosquito repellent, nets, long sleeves, and air conditioning. We estimated an adjusted annual force of infection of 0.014 (95% CI 0.003–0.054) per year spent in dengue-endemic areas (67.3 years to 60% seropositivity), below that of local populations. Our findings suggest that expatriates have a DENV exposure profile distinct from locals and short-term travelers and should likely be considered independently when developing vaccine and prevention recommendations.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"15 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tani Ly, Marcus de Melo Teixeira, Gaston I. Jofre, Denis Blanchet, Sigrid MacDonald, Primavera Alvarado, Silvia Helena Marques da Silva, Victoria E. Sepúlveda, Qandeel Zeb, Stephen Vreden, Antoine Adenis, Francisco Yegres, Magalie Demar, Maria José Serna Buitrago, Bridget M. Barker, Mathieu Nacher, Daniel R. Matute
{"title":"High Genetic Diversity of Histoplasma in the Amazon Basin, 2006–2017","authors":"Tani Ly, Marcus de Melo Teixeira, Gaston I. Jofre, Denis Blanchet, Sigrid MacDonald, Primavera Alvarado, Silvia Helena Marques da Silva, Victoria E. Sepúlveda, Qandeel Zeb, Stephen Vreden, Antoine Adenis, Francisco Yegres, Magalie Demar, Maria José Serna Buitrago, Bridget M. Barker, Mathieu Nacher, Daniel R. Matute","doi":"10.3201/eid3106.241386","DOIUrl":"https://doi.org/10.3201/eid3106.241386","url":null,"abstract":"<p>Histoplasmosis is one of the most common pulmonary mycosis diseases in the world. Genome sequencing has revealed that <em>Histoplasma</em>, the cause of histoplasmosis, is composed of several phylogenetic species. The genetic diversity of the pathogen remains largely unknown, especially in the tropics. We sequenced the genomes of 91 <em>Histoplasma</em> isolates from the Amazon basin of South America and used phylogenomics and population genetic evidence to measure the genetic variation of the genus in South America. We report a previously unidentified clade of <em>Histoplasma</em> endemic to the Amazon basin. The lineage is widespread across the continent and contains 5 lineages that are sufficiently differentiated to be considered phylogenetic species. We found the geographic range of those lineages is largely but not completely overlapping. Finally, we found that the patient median age and sex ratio differs among species, suggesting differences in the epidemiology of histoplasmosis caused by each <em>Histoplasma</em> lineage.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"37 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144104731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Art of the Interwoven","authors":"Byron Breedlove","doi":"10.3201/eid3106.ac3106","DOIUrl":"https://doi.org/10.3201/eid3106.ac3106","url":null,"abstract":"About the Cover","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144067197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}