Emerging Infectious Diseases最新文献_第3页

Population-Based Matched Cohort Study of COVID-19 Healthcare Costs, Ontario, Canada.

IF 7.2 2区医学

Emerging Infectious Diseases Pub Date : 2025-04-01 DOI: 10.3201/eid3104.241463

Beate Sander, Sharmistha Mishra, Sarah Swayze, Yeva Sahakyan, Raquel Duchen, Kieran Quinn, Naveed Janjua, Hind Sbihi, Jeffrey Kwong

{"title":"Population-Based Matched Cohort Study of COVID-19 Healthcare Costs, Ontario, Canada.","authors":"Beate Sander, Sharmistha Mishra, Sarah Swayze, Yeva Sahakyan, Raquel Duchen, Kieran Quinn, Naveed Janjua, Hind Sbihi, Jeffrey Kwong","doi":"10.3201/eid3104.241463","DOIUrl":"10.3201/eid3104.241463","url":null,"abstract":"Estimates of COVID-19-related healthcare costs are key to health system planning, but attributable cost data remain limited. We characterized healthcare costs attributable to COVID-19 through a population-based matched cohort study in Ontario, Canada, by using health administrative data. We matched SARS-CoV-2-positive persons from 2020 to unexposed historical control persons from 2016-2018. We estimated phase-based and survival-adjusted COVID-19-attributable healthcare costs from the health system perspective. We matched 159,817 persons. Mean (95% CI) attributable 10-day costs per person were $1 ($-4 to $6) preindex, $240 ($231-$249) during acute care, $18 ($14-$21) in postacute phases, $3,928 ($3,471-$4,384) in the terminal phase for early deaths, and $1,781 ($1,182-$2,380) for late deaths. Mean cumulative survival-adjusted cost at 360 days was $2,553 ($2,348-$2,756) per person. SARS-CoV-2 infection is associated with substantial long-term healthcare costs, consistent with understanding of post-COVID condition. Determining phase-specific costs can inform budget and pandemic planning.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 4","pages":"710-719"},"PeriodicalIF":7.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strategies and Opportunities to Improve Community Health through Advanced Molecular Detection and Genomic Surveillance of Infectious Diseases

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-04-01 DOI: 10.3201/eid3113.241408

Jazmyn Moore, Ruth Sanon, Yury Khudyakov, Nathelia Barnes

引用次数: 0

Neutralizing Antibodies against California Serogroup Orthobunyaviruses in Human Serum Samples, Montana, USA.

IF 7.2 2区医学

Emerging Infectious Diseases Pub Date : 2025-04-01 DOI: 10.3201/eid3104.241520

Tyson A Woods, Stephen F Johnson, Alyssa B Evans, Karin E Peterson

{"title":"Neutralizing Antibodies against California Serogroup Orthobunyaviruses in Human Serum Samples, Montana, USA.","authors":"Tyson A Woods, Stephen F Johnson, Alyssa B Evans, Karin E Peterson","doi":"10.3201/eid3104.241520","DOIUrl":"10.3201/eid3104.241520","url":null,"abstract":"Viral encephalitis is often underreported and undiagnosed. To understand the potential causes of viral encephalitis in the state of Montana, USA, we examined the relative incidence of human infections for the California serogroup (CSG) of Orthobunyaviruses by screening random convenience serum samples obtained from different hospitals across Montana. We initially screened deidentified samples for neutralizing antibodies against Jamestown Canyon virus (JCV), a CSG virus that has caused encephalitis in Montana. We then analyzed JCV-positive samples for neutralization of other CSG viruses, and detected neutralizing antibodies against La Crosse virus, California encephalitis virus, and Trivittatus virus. We also found a high level of cross-reactivity, particularly between JCV and California encephalitis virus. Our findings indicate that the relative CSG virus infection rates in humans are quite high, between 21% and 40%. Clinicians should consider CSG viruses in differential diagnosis for cases of encephalitis of unknown etiology in Montana.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 4","pages":"699-709"},"PeriodicalIF":7.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oz Virus Infection in 6 Animal Species, Including Macaques, Bears, and Companion Animals, Japan.

IF 7.2 2区医学

Emerging Infectious Diseases Pub Date : 2025-04-01 DOI: 10.3201/eid3104.241574

Aya Matsuu, Kango Tatemoto, Keita Ishijima, Ayano Nishino, Yusuke Inoue, Eunsil Park, Hiroo Tamatani, Junji Seto, Hideo Higashi, Yuichi Fukui, Takashi Noma, Kandai Doi, Rumiko Nakashita, Haruhiko Isawa, Shinji Kasai, Ken Maeda

{"title":"Oz Virus Infection in 6 Animal Species, Including Macaques, Bears, and Companion Animals, Japan.","authors":"Aya Matsuu, Kango Tatemoto, Keita Ishijima, Ayano Nishino, Yusuke Inoue, Eunsil Park, Hiroo Tamatani, Junji Seto, Hideo Higashi, Yuichi Fukui, Takashi Noma, Kandai Doi, Rumiko Nakashita, Haruhiko Isawa, Shinji Kasai, Ken Maeda","doi":"10.3201/eid3104.241574","DOIUrl":"10.3201/eid3104.241574","url":null,"abstract":"Oz virus (OZV) was isolated from an Amblyomma tick in Japan and shown to cause lethal viral myocarditis in humans. However, the natural reservoirs and the distribution of OZV remain unknown. We describe epidemiologic studies conducted by using serum samples collected from mammals throughout Japan. The results showed that 27.5% of wild boars, 56.1% of Sika deer, 19.6% of Japanese macaques, and 51.0% of Asian black bears were positive for virus-neutralizing antibodies against OZV. Approximately 2.8% of dogs and 1.0% of cats also were seropositive. OZV RNA was not detected in any of the examined animal serum samples. Most seropositive animals were distributed in central and western Japan. OZV infects a wide range of animal species, including companion animals and nonhuman primates, and is distributed through central and western Japan, suggesting that further countermeasures are required to prevent this tickborne zoonotic infection.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"31 4","pages":"720-727"},"PeriodicalIF":7.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11950278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-Circulation of 2 Oropouche Virus Lineages during Outbreak, Amazon Region of Peru, 2023-2024.

IF 7.2 2区医学

Emerging Infectious Diseases Pub Date : 2025-04-01 Epub Date: 2024-03-10 DOI: 10.3201/eid3104.241748

Cristhopher D Cruz, Victoria Espejo, Angelica Espinoza, Roger M Castillo-Oré, Gilda Troncos, Julia S Ampuero, Maria E Silva

引用次数: 0

Correction: Vol. 31, No. 3

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-03-26 DOI: 10.3201/eid3105.c13105

引用次数: 0

Correction: Vol. 31, No. 3

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-03-26 DOI: 10.3201/eid3105.c23105

引用次数: 0

Establishing Methods to Monitor Influenza (A)H5N1 Virus in Dairy Cattle Milk, Massachusetts, USA

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-03-26 DOI: 10.3201/eid3113.250087

Elyse Stachler, Andreas Gnirke, Kyle McMahon, Michael Gomez, Liam Stenson, Charelisse Guevara-Reyes, Hannah Knoll, Toni Hill, Sellers Hill, Katelyn S. Messer, Jon Arizti-Sanz, Fatinah Albeez, Elizabeth Curtis, Pedram Samani, Natalia Wewior, David H. O’Connor, William Vuyk, Sophia E. Khoury, Matthew K. Schnizlein, Nicole C. Rockey, Zachariah Broemmel, Michael Mina, Lawrence C. Madoff, Shirlee Wohl, Lorraine O’Connor, Catherine M. Brown, Al Ozonoff, Daniel J. Park, Bronwyn L. MacInnis, Pardis C. Sabeti

{"title":"Establishing Methods to Monitor Influenza (A)H5N1 Virus in Dairy Cattle Milk, Massachusetts, USA","authors":"Elyse Stachler, Andreas Gnirke, Kyle McMahon, Michael Gomez, Liam Stenson, Charelisse Guevara-Reyes, Hannah Knoll, Toni Hill, Sellers Hill, Katelyn S. Messer, Jon Arizti-Sanz, Fatinah Albeez, Elizabeth Curtis, Pedram Samani, Natalia Wewior, David H. O’Connor, William Vuyk, Sophia E. Khoury, Matthew K. Schnizlein, Nicole C. Rockey, Zachariah Broemmel, Michael Mina, Lawrence C. Madoff, Shirlee Wohl, Lorraine O’Connor, Catherine M. Brown, Al Ozonoff, Daniel J. Park, Bronwyn L. MacInnis, Pardis C. Sabeti","doi":"10.3201/eid3113.250087","DOIUrl":"https://doi.org/10.3201/eid3113.250087","url":null,"abstract":"Highly pathogenic avian influenza A(H5N1) virus has caused a multistate outbreak among US dairy cattle, spreading across 16 states and infecting hundreds of herds since its onset. We rapidly developed and optimized PCR-based detection assays and sequencing protocols to support H5N1 molecular surveillance. Using 214 retail milk samples from 20 states for methods development, we found that H5N1 virus concentrations by digital PCR strongly correlated with quantitative PCR cycle threshold values; digital PCR exhibited greater sensitivity. Metagenomic sequencing after hybrid selection was best for higher concentration samples, whereas amplicon sequencing performed best for lower concentrations. By establishing these methods, we were able to support the creation of a statewide surveillance program to perform monthly testing of bulk milk samples from all dairy cattle farms in Massachusetts, USA, which remain negative to date. The methods, workflow, and recommendations described provide a framework for others aiming to conduct H5N1 surveillance efforts.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"50 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143713541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Vol. 31, No. 2

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-03-26 DOI: 10.3201/eid3105.c33105

引用次数: 0

Epidemiology of Tularemia among Humans and Animals, Baden-Wuerttemberg, Germany, 2012–2022

IF 11.8 2区医学

Emerging Infectious Diseases Pub Date : 2025-03-21 DOI: 10.3201/eid3104.240414

Sabrina Nothdurfter, Jörg Linde, Reinhard Sting, Herbert Tomaso, Klaus Heuner, Maylin Meincke, Stefan O. Brockmann, Christiane Wagner-Wiening

{"title":"Epidemiology of Tularemia among Humans and Animals, Baden-Wuerttemberg, Germany, 2012–2022","authors":"Sabrina Nothdurfter, Jörg Linde, Reinhard Sting, Herbert Tomaso, Klaus Heuner, Maylin Meincke, Stefan O. Brockmann, Christiane Wagner-Wiening","doi":"10.3201/eid3104.240414","DOIUrl":"https://doi.org/10.3201/eid3104.240414","url":null,"abstract":"Tularemia, a zoonosis caused by Francisella tularensis, is endemic in Baden-Wuerttemberg, Germany. To determine tularemia epidemiology in this region, we characterized the genetic diversity of F. tularensis in human and animal isolates during 2012–2022 by using whole-genome sequencing, combined with human and veterinary surveillance data analysis. Human case numbers varied; most cases occurred in 2021 (n = 34). Arthropod bites were reported most in cases with information on animal exposure (45%, n = 43). Poisson regression confirmed a significant increase in human cases during the study period (p<0.001). No seasonal pattern was identified, but case numbers were lowest in winter. Human surveillance data often lacked exposure details. Positivity rates in animals were 5%–34%, increasing since 2017. Human isolates often clustered with hare-derived strains, although transmission routes often remain unclear. These findings emphasize the importance of combining genome sequencing with detailed epidemiologic tracing to identify infection sources and improve surveillance data.","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"56 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143672746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0