Rhys H. Parry, KayLene Y.H. Yamada, Wendy R. Hood, Yang Zhao, Jinlong Y. Lu, Andrei Seluanov, Vera Gorbunova, Naphak Modhiran, Daniel Watterson, Ariel Isaacs
{"title":"Henipavirus in Northern Short-Tailed Shrew, Alabama, USA","authors":"Rhys H. Parry, KayLene Y.H. Yamada, Wendy R. Hood, Yang Zhao, Jinlong Y. Lu, Andrei Seluanov, Vera Gorbunova, Naphak Modhiran, Daniel Watterson, Ariel Isaacs","doi":"10.3201/eid3102.241155","DOIUrl":"https://doi.org/10.3201/eid3102.241155","url":null,"abstract":"<p>RNA metagenomic analysis of tissues from 4 wild-caught northern short-tailed shrews in Alabama, USA, revealed a novel henipavirus (family Paramyxoviridae). Phylogenetic analysis supported the placement of the virus within the shrew henipavirus clade, related to human-infecting shrewborne henipaviruses. Our study results highlight the presence of henipavirus infections in North America.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"30 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christine Marie George, Alves Namunesha, Kelly Endres, Willy Felicien, Presence Sanvura, Jean-Claude Bisimwa, Jamie Perin, Justin Bengehya, Ghislain Maheshe, Cirhuza Cikomola, Lucien Bisimwa, Alain Mwishingo, David A. Sack, Daryl Domman
{"title":"Epidemiologic and Genomic Surveillance of Vibrio cholerae and Effectiveness of Single-Dose Oral Cholera Vaccine, Democratic Republic of the Congo","authors":"Christine Marie George, Alves Namunesha, Kelly Endres, Willy Felicien, Presence Sanvura, Jean-Claude Bisimwa, Jamie Perin, Justin Bengehya, Ghislain Maheshe, Cirhuza Cikomola, Lucien Bisimwa, Alain Mwishingo, David A. Sack, Daryl Domman","doi":"10.3201/eid3102.241777","DOIUrl":"https://doi.org/10.3201/eid3102.241777","url":null,"abstract":"<p>We conducted 4 years of epidemiologic and genomic surveillance of single-dose effectiveness of a killed whole-cell oral cholera vaccine (kOCV) and <em>Vibrio cholerae</em> transmission in the Democratic Republic of the Congo. We enrolled 1,154 patients with diarrhea; 342 of those had culture-confirmed cholera. We performed whole-genome sequencing on clinical and water <em>V. cholerae</em> isolates from 200 patient households, which showed annual bimodal peaks of <em>V. cholerae</em> clade AFR10e infections. A large clonal cholera outbreak occurred 14 months after a kOCV campaign of >1 million doses, likely because of low (9%) vaccine coverage in informal settlements. Clinical and water isolates collected in the same household were closely related, suggesting person-to-person and water-to-person transmission. Single-dose kOCV vaccine effectiveness 24 months after vaccination was 59.8% (95% CI 19.7%–79.9%), suggesting modest single-dose kOCV protection. kOCV campaigns combined with water, sanitation, and hygiene programs should be used to reduce cholera in disease-endemic settings worldwide.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"93 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reemergence of Echinococcus granulosus Infections after 2004 Termination of Control Program in Magallanes Region, Chile","authors":"Cristian A. Alvarez Rojas, Juan Francisco Alvarez","doi":"10.3201/eid3102.240980","DOIUrl":"https://doi.org/10.3201/eid3102.240980","url":null,"abstract":"<p>After termination of a control program in 2004, <em>Echinococcus granulosus</em> infections have reemerged in Magallanes Region, Chile. Prevalence in sheep >2 years of age in 2023 resembled levels observed at the start of the program. Resurgence underscores the need for continued surveillance, particularly in younger sheep, to monitor recent transmission trends.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"77 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexis Siegler, Lauryn Ursery, Dana A. Giandomenico, Melissa B. Miller, Johanna S. Salzer, Alexis M. Barbarin, Carl Williams, Ross M. Boyce
{"title":"Contribution of Limited Molecular Testing to Low Ehrlichiosis Diagnosis in High Incidence Area, North Carolina, USA","authors":"Alexis Siegler, Lauryn Ursery, Dana A. Giandomenico, Melissa B. Miller, Johanna S. Salzer, Alexis M. Barbarin, Carl Williams, Ross M. Boyce","doi":"10.3201/eid3102.240281","DOIUrl":"https://doi.org/10.3201/eid3102.240281","url":null,"abstract":"<p>Indirect immunofluorescence antibody assays have been the primary method for laboratory diagnosis of ehrlichiosis. Detection of <em>Ehrlichia</em> spp. DNA by using PCR is now widely available through commercial laboratories. To prepare for <em>Ehrlichia</em> spp. PCR introduction, we assessed ehrlichiosis testing practices, quantified the proportion of samples eligible for PCR testing, and estimated the potential effect of implementing PCR at the University of North Carolina health system in North Carolina, USA, which is in an area with a high-incidence of ehrlichiosis. We found <1% of patient samples underwent PCR testing, even though rates of serodiagnostic algorithm completion (testing of acute and convalescent samples) were low (18.4%). Our findings show a need to educate providers on diagnostic and treatment guidelines for ehrlichiosis and raise awareness of the availability and advantage of PCR testing. </p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"22 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jérémie Prévost, Nikesh Tailor, Anders Leung, Bryce Warner, David Safronetz
{"title":"Sin Nombre Virus as Unlikely Reverse Zoonotic Threat","authors":"Jérémie Prévost, Nikesh Tailor, Anders Leung, Bryce Warner, David Safronetz","doi":"10.3201/eid3102.241532","DOIUrl":"https://doi.org/10.3201/eid3102.241532","url":null,"abstract":"<p>We inoculated clinical materials into deer mice to attempt isolation of Sin Nombre virus. We did not observe productive infection in the natural rodent reservoir. Genomic comparisons between rodent reservoirs and human disease may provide insight into hantavirus evolution and genetic determinants, but reverse zoonosis of Sin Nombre virus appears unlikely. </p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"45 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Borrelia spielmanii–Associated Neuroborreliosis in Patient Receiving Rituximab, Belgium","authors":"Timothée Carette, Louisien Lebrun, Benoît Kabamba-Mukadi, Jean-Marc Raymackers, Jean-Louis Bayart","doi":"10.3201/eid3102.240777","DOIUrl":"https://doi.org/10.3201/eid3102.240777","url":null,"abstract":"<p>A 58-year-old woman in Belgium with a history of follicular lymphoma treated with rituximab sought care for a rapid sensory-motor deficit. Seronegative neuroborreliosis caused by <em>Borrelia spielmanii</em> was diagnosed, likely related to humoral deficiency. High CXC motif chemokine ligand 13 levels and PCR confirmed the diagnosis. Ceftriaxone treatment led to full recovery.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"6 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Terry Komo, Patrick K. Munywoki, Maria da Gloria Carvalho, Joshua Auko, Alice Ouma, Allan Audi, George O. Agogo, Daniel Omondi, Arthur Odoyo, Herine Odiembo, Newton Wamola, Mike Osita, Clayton Onyango, Naomi Lucchi, Peninah Munyua, Amy Herman-Roloff, Shanda Larson, Sopio Chochua, Fabiana C. Pimenta, Godfrey Bigogo, Jennifer R. Verani
{"title":"Outbreak of Serotype 1 Invasive Pneumococcal Disease, Kibera Urban Informal Settlement, Nairobi, Kenya, 2023","authors":"Terry Komo, Patrick K. Munywoki, Maria da Gloria Carvalho, Joshua Auko, Alice Ouma, Allan Audi, George O. Agogo, Daniel Omondi, Arthur Odoyo, Herine Odiembo, Newton Wamola, Mike Osita, Clayton Onyango, Naomi Lucchi, Peninah Munyua, Amy Herman-Roloff, Shanda Larson, Sopio Chochua, Fabiana C. Pimenta, Godfrey Bigogo, Jennifer R. Verani","doi":"10.3201/eid3102.241652","DOIUrl":"https://doi.org/10.3201/eid3102.241652","url":null,"abstract":"<p>Use of 10-valent pneumococcal conjugate vaccine in Kenya has led to substantial reductions in vaccine-type pneumococcal carriage and invasive pneumococcal disease. However, analysis of recent surveillance data indicates an outbreak of vaccine-type serotype 1 in 2023 in Kibera, Kenya. Continued monitoring of invasive pneumococcal disease in Kenya is warranted.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"30 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142988352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bjerkandera adusta Fungi as Causative Agent of Invasive Chronic Rhinosinusitis","authors":"Yuhei Kurata, Yoshifumi Kimizuka, Takashi Yaguchi, Kanshu Ito, Tetsuya Yamamoto, Yusuke Serizawa, Akira Kamiya, Takaaki Hamamoto, Taishi Sakima, Tomomi Tanigaki, Hiromi Edo, Yu Hongo, Akira Watanabe, Kazushi Suzuki, Terushige Toyooka, Akihiko Kawana","doi":"10.3201/eid3102.241275","DOIUrl":"https://doi.org/10.3201/eid3102.241275","url":null,"abstract":"<p>We report an invasive mycosis case in Japan caused by <em>Bjerkandera adusta</em>, a fungal species not previously reported as a causative pathogen of invasive mycosis. <em>B. adusta</em> was identified by using phylogenetic analysis. Voriconazole was used successfully for treatment. Immunodeficient patients may be susceptible to infection by rare causative fungi.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"50 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John Newman, Caitlin Hughes, Karen C. Bloch, Khalil J. Deveaux, Scott Allen, Thao T. Truong, Behzad Najafian, Abelardo C. Moncayo, Lili Tao, Joshua Lieberman, Hernán Correa
{"title":"Infection by Tickborne Bacterium Candidatus Midichloria Associated with First Trimester Pregnancy Loss, Tennessee, USA","authors":"John Newman, Caitlin Hughes, Karen C. Bloch, Khalil J. Deveaux, Scott Allen, Thao T. Truong, Behzad Najafian, Abelardo C. Moncayo, Lili Tao, Joshua Lieberman, Hernán Correa","doi":"10.3201/eid3102.240870","DOIUrl":"https://doi.org/10.3201/eid3102.240870","url":null,"abstract":"<p>A previously healthy 26-year-old woman in middle Tennessee, USA, experienced a first trimester pregnancy loss after multiple tick bites. Histopathology, 16S rRNA sequencing, and electron microscopy examination of the products of conception revealed an infection by a bacterium within the <em>Candidatus</em> Midichloria genus.</p>","PeriodicalId":11595,"journal":{"name":"Emerging Infectious Diseases","volume":"14 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}