Endoscopic UltrasoundPub Date : 2023-05-01Epub Date: 2023-07-25DOI: 10.1097/eus.0000000000000007
Bojan Kovacevic, Anders Toxværd, Pia Klausen, Michael H Larsen, Simon Grützmeier, Sönke Detlefsen, John Gásdal Karstensen, Lene Brink, Hazem Hassan, Estrid Høgdall, Peter Vilmann
{"title":"Tissue amount and diagnostic yield of a novel franseen EUS-FNB and a standard EUS-FNA needle-A randomized controlled study in solid pancreatic lesions.","authors":"Bojan Kovacevic, Anders Toxværd, Pia Klausen, Michael H Larsen, Simon Grützmeier, Sönke Detlefsen, John Gásdal Karstensen, Lene Brink, Hazem Hassan, Estrid Høgdall, Peter Vilmann","doi":"10.1097/eus.0000000000000007","DOIUrl":"10.1097/eus.0000000000000007","url":null,"abstract":"<p><strong>Background and objectives: </strong>Several types of needles are available for EUS-guided tissue sampling of pancreatic lesions. Whereas fine-needle aspiration (FNA) needles typically provide cytological samples, fine-needle biopsy (FNB) needles are designed to obtain microcores with preserved tissue architecture. The aim of this study was to compare tissue amount and diagnostic yield between a modified Franseen-type FNB needle (TopGain; Medi-Globe GmbH, Grassau, Germany) and a standard FNA needle.</p><p><strong>Methods: </strong>We performed a prospective, multicenter randomized controlled study between June 2020 and September 2021, including patients with a solid pancreatic lesion referred for EUS-guided tissue sampling at 3 centers in Denmark. The patients were randomized 1:1 to either FNA needle or the novel FNB needle. Primary outcomes included the number of obtained tissue microcores and total and diagnostic tissue area.</p><p><strong>Results: </strong>Sixty-four patients were included. The median number of tissue microcores procured per pass was significantly higher in the FNB group compared with FNA (3 <i>vs</i>. 2, <i>P</i> < 0.001). Similarly, the mean total tissue area (2.74 <i>vs</i>. 0.44 mm<sup>2</sup>, <i>P</i> < 0.001) and mean diagnostic tissue area (1.74 <i>vs</i>. 0.28 mm<sup>2</sup>, <i>P</i> < 0.001) were more than 6-fold larger in the FNB samples compared with FNA. The median number of passes needed for a diagnostic sample was 1 for the FNB needle and 2 for FNA needle (<i>P</i> = 0.12). The novel FNB needle provided a higher percentage of samples of excellent quality (<i>P</i> = 0.002).</p><p><strong>Conclusions: </strong>The novel Franseen-type FNB needle seems to be significantly superior to a conventional FNA needle. The results of this study underline excellent performance of crown-cut needles.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"12 3","pages":"319-325"},"PeriodicalIF":4.5,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ff/82/eusj-12-319.PMC10437204.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10225150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endoscopic UltrasoundPub Date : 2023-05-01Epub Date: 2023-07-25DOI: 10.1097/eus.0000000000000021
Wen Shi, Zhiwei Wang, Di Shi, Xi Wu, Aiming Yang, Yunlu Feng
{"title":"A stent spat up: can EUS-guided biliary drainage stents be removed now that cancer patients live longer?","authors":"Wen Shi, Zhiwei Wang, Di Shi, Xi Wu, Aiming Yang, Yunlu Feng","doi":"10.1097/eus.0000000000000021","DOIUrl":"10.1097/eus.0000000000000021","url":null,"abstract":"A 61-year-old woman with advanced pancreatic cancer presented with fever and jaundice. A duodenal stent had been placed 10 days previously for duodenal obstruction. A computed tomographic scan revealed obstruction of the common bile duct with proximal dilatation [Figure","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"12 3","pages":"349-350"},"PeriodicalIF":4.5,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/ef/eusj-12-349.PMC10437200.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Endoscopic UltrasoundPub Date : 2023-05-01Epub Date: 2023-07-25DOI: 10.1097/eus.0000000000000022
Claudia Lucius, Michael Bachmann Nielsen, Michael Blaivas, Eike Burmester, Susan Campbell Westerway, Chit Yan Chu, George Condous, Xin-Wu Cui, Yi Dong, Gill Harrison, Jonas Koch, Barbara Kraus, Christian Pállson Nolsøe, Leizl Joy Nayahangan, Malene Roland V Pedersen, Adrian Saftoiu, Eric Savitsky, Christoph F Dietrich
{"title":"The use of simulation in medical ultrasound: Current perspectives on applications and practical implementation (WFUMB state-of-the-art paper).","authors":"Claudia Lucius, Michael Bachmann Nielsen, Michael Blaivas, Eike Burmester, Susan Campbell Westerway, Chit Yan Chu, George Condous, Xin-Wu Cui, Yi Dong, Gill Harrison, Jonas Koch, Barbara Kraus, Christian Pállson Nolsøe, Leizl Joy Nayahangan, Malene Roland V Pedersen, Adrian Saftoiu, Eric Savitsky, Christoph F Dietrich","doi":"10.1097/eus.0000000000000022","DOIUrl":"10.1097/eus.0000000000000022","url":null,"abstract":"<p><p>Simulation has been shown to improve clinical learning outcomes, speed up the learning process, and improve trainee confidence, while taking the pressure off initial face-to-face patient clinical areas. The second part of The World Federation for Ultrasound in Medicine and Biology state-of-the-art paper on the use of simulators provides a general approach on the practical implementation. The importance of needs assessment before developing a simulation-based training program is outlined. We describe the current practical implementation and critically analyze how simulators can be integrated into complex task scenarios to train small or large groups. A wide range of simulation equipment is available especially for those seeking interventional ultrasound training, ranging from animal tissue models, simple synthetic phantoms, to sophisticated high-fidelity simulation platforms using virtual reality. Virtual reality simulators provide feedback and thereby allow trainees to not only to practice their motor skills and hand eye coordination but also to interact with the simulator. Future developments will integrate more elements of automated assessment and artificial intelligence, thereby enabling enhanced realistic training experience and improving skill transfer into clinical practice.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"12 3","pages":"311-318"},"PeriodicalIF":4.4,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/88/eusj-12-311.PMC10437199.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10223035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abstracts from the 53rd Annual Scientific Meeting of the British Medical Ultrasound Society, 6–8 December 2022, City Hall, Cardiff, UK","authors":"L. Marsden","doi":"10.1177/1742271X231165179","DOIUrl":"https://doi.org/10.1177/1742271X231165179","url":null,"abstract":"We present how we used ultrasound to improve our diagnosis of lung Covid 19 and use ultrasound to diagnose the complications of Covid 19. Ultrasound was more sensitive in detecting early Covid 19 than chest radiograph. The complications of Covid 19 include renal impairment, liver impairment and vascular complications, mainly large vessel venous thrombosis, including renal vein thrombosis. We are all suffering from post-viral fatigue but lessons can be learnt from this pandemic and the use of ultrasound.","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"86 1","pages":"NP1 - NP40"},"PeriodicalIF":4.5,"publicationDate":"2023-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88395729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Troubleshooting the migration of a double-pigtail plastic stent into a pelvic abscess (with videos).","authors":"Koichi Soga, Hiroaki Kitae","doi":"10.4103/EUS-D-22-00161","DOIUrl":"10.4103/EUS-D-22-00161","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"12 2","pages":"303-304"},"PeriodicalIF":4.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0c/4f/EUS-12-303.PMC10237605.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of biological effect of nab-paclitaxel combined with gemcitabine, using contrast enhanced ultrasonography and elastography, in advanced pancreatic ductal carcinoma: A single-center pilot study.","authors":"Yanis Dahel, Brice Chanez, Christophe Zemmour, Gilles Piana, Emmanuel Mitry, Marc Giovannini","doi":"10.4103/EUS-D-22-00040","DOIUrl":"10.4103/EUS-D-22-00040","url":null,"abstract":"<p><p>EUS associated with contrast-enhanced harmonic EUS (CH-EUS) and EUS elastography (EUS-E) are used in clinical practice to assess pancreatic tumor at the diagnosis. In case of pancreatic ductal adenocarcinoma (PDAC) with liver metastasis, nab-paclitaxel combined with gemcitabine is a first-line treatment option. We aimed to assess the modification of PDAC microenvironment induced by the combination of nab-paclitaxel with gemcitabine, by endoscopic ultrasonography techinics. This single center phase III study conducted between February 2015 and June 2016 included patients with pancreatic adenocarcinoma with mesurable liver metastasis and no prior cancer treatment fit for two cycles of nab-paclitaxel combined with gemcitabine. We aimed to perform EUS with CH-EUS and EUS-E of the pancreatic tumor, CT scan and contrast enhanced ultrasonogram (CE-US) of a reference liver metastasis, before and after the two cylces of chemotherapy. Primary end point was modification of vascularizaion of primary tumor and a reference liver metastasis. Secondary end points were modification of stromal content, safety profile of drug combination and tumor response rate. Sixteen patients were analyzed, but only 13 received two cycled of chemotherapy (CT) (toxicity [n = 1] or death [n = 2]). There was no statistical modification induced by CT concering vascularity of primary tumor (time to maximum intensity P = 0.24, value of maximum intensity P = 0.71, hypoechogenic aspect generated by injection of contrast enhancing agent), vascularity of a reference liver metastasis (time to maximum intensity P = 0.99, value of maximum intensity P = 0.71) and tumor elasticity (P = 0.22). Eleven patients had tumor response assessement, 6/11 (54%) had measurable disease response 4/11 (36%) with partial responses and 2/11 (18%) with stable disease. All other patients showed disease progression. No serious side effects occurred, 6/11 patients had a dose adjustment. We did not show significant modification of vascularity and elasticity but these results should be taken with caution because of important limitations.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"12 2","pages":"273-276"},"PeriodicalIF":4.5,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/68/37/EUS-12-273.PMC10237618.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9558098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}