Endoscopic Ultrasound最新文献

{"title":"Long-term prognosis and risk factor-based surveillance strategy for patients with small gastric subepithelial lesion using endoscopic ultrasonography.","authors":"Jong Sun Park, Ji Hyun Park, Bumhee Park, Jong Hoon Park, Sun Gyo Lim, Sung Jae Shin, Kee Myung Lee, Sung Soo Ahn, Choong-Kyun Noh, Gil Ho Lee","doi":"10.1097/eus.0000000000000166","DOIUrl":"10.1097/eus.0000000000000166","url":null,"abstract":"<p><strong>Background and objectives: </strong>Initial surveillance strategy and subsequent monitoring for small gastric subepithelial lesions (SELs) lack a consensus. This study aimed to investigate the risk factors and performance of predictive markers for lesions requiring surgical intervention in patients with small gastric SELs.</p><p><strong>Methods: </strong>We retrospectively reviewed data of patients who underwent EUS at least twice between 2010 and 2023. Group S1 was defined as patients with a ≥20% increase in size from the initial EUS. The S1 was further divided into 2 groups according to requiring surgical intervention (S2 and S3).</p><p><strong>Results: </strong>Of the 476 patients, 106 (22.2%) had increase in size by ≥20% compared with the initial EUS (S1). The mean follow-up duration in the S1 was 70.2 months. Seven (1.5%) and 38 (8.0%) lesions were observed to have increased in size and were confirmed as gastrointestinal stromal tumors, respectively (S2). Lesions in the lesser curvature (odds ratio [OR]: 6.0, 95% confidence interval [CI]: 2.087-17.148, <i>P</i> < 0.001) and size of ≥12.8 mm (OR: 4.2, 95% CI: 2.083-8.542, <i>P</i> < 0.001) were risk factors for S2. Lesion size ≥12.8 mm is a key risk factor requiring timely intervention based on the Kaplan-Meier analysis. An increasing rate (0.7 mm/yr) showed superior performance as a predictive risk factor for S2 than having a lesion size ≥12.8 mm (area under the receiver-operating characteristic curve: 0.887 <i>vs.</i> 0.734, <i>P</i> < 0.001).</p><p><strong>Conclusions: </strong>Although the size of the SELs increased, the classification for group S2 was very important. These results emphasize the necessity for effective follow-up strategies, including timely interventions, for small gastric SELs.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"15 1","pages":"62-70"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13048641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Device failures and patient adverse events from EUS: 26-year FDA MAUDE analysis (2000-2025).","authors":"Sijia Zhai, Xiaolu Lin, Yiming Song, Zeyu Li, Jingjing Chen, Xiaojie Huang, Zhongge Ji, Qingran Liu, Yufei Xiao, Ruijie Han, Ruitian Zeng, Yuxin Yang, Qingwei Zhang, Wanyin Deng, Xiaobo Li","doi":"10.1097/eus.0000000000000170","DOIUrl":"10.1097/eus.0000000000000170","url":null,"abstract":"<p><strong>Background and objectives: </strong>EUS has emerged as an essential instrument in the field of gastroenterology, significantly enhancing both diagnostic evaluations and therapeutic procedures. By delivering high-resolution imaging and precise guidance, EUS facilitates a range of interventional techniques. This study sought to examine the adverse events linked to EUS devices following their approval by the US Food and Drug Administration.</p><p><strong>Methods: </strong>We performed a retrospective analysis utilizing postmarketing surveillance data sourced from the Food and Drug Administration's Manufacturer and User Facility Device Experience (MAUDE) database. This analysis encompasses data from January 1, 2000, to August 31, 2025.</p><p><strong>Results: </strong>A total of 7608 reports detailing 8778 device-related issues and 7875 patient complications were analyzed. The most commonly reported device-related problems included peeling or delamination, with 1251 reports, followed by device breakage at 837 reports, microbial contamination at 781 reports, and inadequate cleaning at 704 reports. In terms of patient-related complications, the most frequently reported adverse events were blood loss (73 reports), tissue perforation (44 reports), and pancreatitis (32 reports). Furthermore, there were 743 documented instances of microbial contamination in EUS devices, with <i>Coagulase-negative staphylococci</i> being identified as the predominant pathogen, appearing in 151 reports.</p><p><strong>Conclusions: </strong>The examination of the MAUDE database reveals significant device and patient-related adverse events that endoscopists must consider during EUS procedures. Continuous postmarketing surveillance and the evaluation of real-world data are crucial for determining the safety and effectiveness of endoscopic devices, which in turn enhances patient outcomes.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"15 1","pages":"39-48"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13048624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147621917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective evaluation study of EUS-guided hepaticogastrostomy without tract dilation: Comparison to with tract dilation.","authors":"Mitsuki Tomita, Takeshi Ogura, Akitoshi Hakoda, Saori Ueno, Atsushi Okuda, Nobu Nishioka, Jun Matsuno, Nobuhiro Hattori, Junichi Nakamura, Takafumi Kanadani, Kimi Bessho, Hiroki Nishikawa","doi":"10.1097/eus.0000000000000148","DOIUrl":"10.1097/eus.0000000000000148","url":null,"abstract":"<p><strong>Background and objectives: </strong>During EUS-guided hepaticogastrostomy (EUS-HGS), bile leak usually occurs in the interval between tract dilation and stent deployment. Recently, a novel partially covered self-expandable metal stent (PCSEMS) with fine gauge stent delivery system (5.9Fr) has become available. Therefore, the aim of this prospective study was to evaluate the technical feasibility of EUS-HGS using this novel stent without tract dilation and compare it with EUS-HGS with tract dilation.</p><p><strong>Method: </strong>Patients with biliary disease who required EUS-BD were eligible for enrollment in this study. The primary outcome was the technical success rate of stent deployment without tract dilation.</p><p><strong>Results: </strong>The technical success rate of the one-step technique was 92.0% (23/25). Mean procedure time was 10.1 min, and the clinical success rate was 96% (24/25). As adverse events, bile peritonitis and stent migration were observed in one patient each. As historical controls, 75 patients who underwent EUS-HGS were enrolled in this study. As adverse events, bile peritonitis was observed in eight patients and cholangitis in three patients. After propensity score matching analysis, procedure time was significantly shorter in the one-step group compared with the two-step group (9.84 <i>vs</i>. 19.0 min, <i>P</i> < 0.001). In addition, bile peritonitis as an adverse event was significantly more frequent in the two-step group than the one-step group (<i>P</i> = 0.018).</p><p><strong>Conclusions: </strong>In conclusion, EUS-HGS using this novel PCSEMS might be feasible and safe, and performance of tract dilation might influence the occurrence of bile peritonitis.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"15 1","pages":"49-56"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13048639/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative diagnosis of a recurrent anaplastic lymphoma kinase-negative inflammatory myofibroblastic tumor of the sigmoid colon using EUS-guided fine-needle aspiration: A case report.","authors":"Ning Xie, Yutong Cheng, Tao Wu, Li Miao, Zhe Kang, Haitao Shi","doi":"10.1097/eus.0000000000000167","DOIUrl":"10.1097/eus.0000000000000167","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"15 1","pages":"79-81"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13048667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary hepatic neuroendocrine neoplasm (with video).","authors":"Ming Zhao, Xi Zhou, Xiaobin Sun, Jing Shan","doi":"10.1097/eus.0000000000000169","DOIUrl":"10.1097/eus.0000000000000169","url":null,"abstract":"","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"15 1","pages":"84-85"},"PeriodicalIF":4.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13048670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147622110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning curve and predictors of technical failure in EUS-guided antegrade interventions: A retrospective analysis of 138 consecutive cases.","authors":"Dexin Chen, Senlin Hou, Yongzhan Zhao, Min Zhu, Mingyang Li, Lichao Zhang","doi":"10.1097/eus.0000000000000160","DOIUrl":"10.1097/eus.0000000000000160","url":null,"abstract":"<p><strong>Background and objectives: </strong>EUS-guided biliary drainage (EUS-BD) is an alternative to ERCP for patients with altered anatomy or duodenal obstruction. EUS-guided antegrade intervention (EUS-AG) offers physiological drainage with lower reintervention rates and higher stent patency. However, the technical complexity of EUS-AG limits its success rate, and factors associated with technical failure remain controversial. This study aimed to evaluate the learning curve for EUS-AG and identify predictors of technical failure.</p><p><strong>Patients and methods: </strong>A cohort of 138 patients intended for EUS-AG between December 2019 and January 2025 was analyzed. CUSUM analysis was used to assess the learning curve based on procedure time. Technical failure was defined as failure to advance the antegrade guidewire across the duodenal papilla or bilioenteric anastomosis, failure of stent deployment, or failure to extract stones. Univariable and multivariable logistic regression analyses were performed to identify independent predictors of technical failure.</p><p><strong>Results: </strong>The overall technical success rate of EUS-AG was 78.2% (108/138). The CUSUM learning curve demonstrated a significant decrease in procedure time after 50 cases, indicating the transition to the proficiency phase. Multivariable analysis identified preproficiency phase (OR, 9.70; 95% CI, 2.91-32.30; <i>P</i> < 0.001), hilar bile duct obstruction (HBO) (OR, 14.36; 95% CI, 3.41-60.49; <i>P</i> < 0.001), and excessive bile duct dilation (EBD) (OR, 17.09; 95% CI, 4.80-60.89; <i>P</i> < 0.001) as independent predictors of technical failure.</p><p><strong>Conclusion: </strong>For endoscopists with proficient ERCP experience, the EUS-AG learning curve plateaued after approximately 50 cases. The preproficiency phase, HBO, and EBD were identified as independent predictors of technical failure.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"14 6","pages":"343-350"},"PeriodicalIF":5.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AI-assisted rapid on-site evaluation ROSE of EUS-FNA cytopathology for pancreatic solid lesions: A two-stage deep learning approach.","authors":"Yuan Tian, Jixin Zhang, Xiaolong Rao, Bin Zhou, Xudong Zhao, Yan He, Haiqiang Sheng, Weidong Nian, Yunlong Cai, Long Rong","doi":"10.1097/eus.0000000000000154","DOIUrl":"10.1097/eus.0000000000000154","url":null,"abstract":"<p><strong>Background: </strong>EUS-guided fine-needle aspiration (EUS-FNA) combined with rapid on-site evaluation (ROSE) is crucial for diagnosing pancreatic solid lesions. However, the widespread application of ROSE faces challenges, particularly the limited availability of specialized cytopathologists for immediate interpretation. Furthermore, the inherent variability in EUS-FNA sample quality (e.g., cellularity and debris) and suboptimal smear preparation during procedures can impede reliable automated analysis.This study aimed to develop and validate a novel 2-stage deep learning-based diagnostic model for the automated analysis of EUS-FNA cytological images of pancreatic solid lesions captured using mobile phones during the ROSE process, with the goal of automating diagnosis and improving efficiency.</p><p><strong>Methods: </strong>We retrospectively collected 882 EUS-FNA cytological images from 92 patients with pancreatic solid lesions at Peking University First Hospital, captured using mobile phones, during ROSE. A 2-stage deep learning model was developed. The first stage utilized YOLOv8n-p2 for robust tissue cell detection, addressing background complexity, and enabling preprocessing steps such as cell size normalization. In the second stage, DenseNet201 was employed to classify the detected cellular regions as malignant or normal. The dataset was divided into training, validation, and testing sets. The model performance was evaluated using a dedicated test set consisting of whole images.</p><p><strong>Results: </strong>On the independent test set, the proposed 2-stage method achieved high performance in classifying images for malignancy, yielding an accuracy of 93.3%, an area under the precision-recall curve (AUC-PR) of 0.958, and an area under the receiver operating characteristic curve (AUC-ROC) of 0.962.</p><p><strong>Conclusion: </strong>The diagnostic accuracy of the proposed AI method is comparable to that of traditional expert-involved ROSE, while offering the potential to significantly reduce diagnostic time and dependency on immediate pathologist availability. This 2-stage deep learning approach effectively analyzes variable mobile phone-captured EUS-FNA images, demonstrating its potential as an automated, AI-assisted diagnostic system for the ROSE process. It holds significant potential for clinical application, particularly in facilitating timely pancreatic cancer diagnosis in resource-constrained settings and in scenarios where on-site pathological expertise is limited.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"14 6","pages":"314-327"},"PeriodicalIF":5.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146051006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and diagnostic yield of 19G <i>versus</i> 22G fine needle biopsy needles in EUS-guided liver biopsy: A systematic review and meta-analysis.","authors":"Harsimran Kalsi, Sahib Singh, Babu P Mohan, Rabindra Watson, Rashmi Advani","doi":"10.1097/eus.0000000000000163","DOIUrl":"10.1097/eus.0000000000000163","url":null,"abstract":"<p><p>EUS-guided liver biopsy (EUS-LB) is an alternative to traditional percutaneous and transjugular approaches. Determining the optimal needle gauge requires balancing diagnostic yield with procedural safety. This meta-analysis compares the efficacy and safety of 19-gauge (19G) <i>versus</i> 22-gauge (22G) fine needle biopsy (FNB) needles in EUS-LB. We searched PubMed, Google Scholar, and Cochrane databases for studies comparing 19G and 22G FNB needles with Franseen or Fork tip designs. Outcomes assessed included tissue adequacy, diagnostic adequacy, number of complete portal tracts (CPTs), length of the longest tissue segment, and total specimen length (TSL). Data were analyzed using a random-effects model, presenting results as standardized mean differences (SMDs) and relative risks (RRs) with 95% confidence intervals (CIs). Five studies with 205 patients were included. The 19G needle demonstrated higher tissue adequacy (RR, 1.596; 95% CI, 0.969-2.631; <i>P</i> = 0.066) and diagnostic adequacy (RR, 1.421; 95% CI, 0.942-2.145; <i>P</i> = 0.094) compared to the 22G needle. It yielded greater CPTs (SMD, 1.705; 95% CI, -0.652 to 4.062; <i>I</i> ² = 97.34%), longer tissue segments (SMD, 5.039; 95% CI, -0.276 to 10.354; <i>I</i> ² = 97.24%), and increased TSL (SMD, 4.156; 95% CI, -0.268 to 8.579; <i>I</i> ² = 98.75%). The 19G needle may provide superior tissue and diagnostic outcomes in EUS-LB without increasing adverse effects compared to the 22G needle, although these differences were not statistically significant. This suggests a need for further high-quality research to confirm these preliminary findings.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"14 6","pages":"297-303"},"PeriodicalIF":5.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does endoscopic magnetic resonance imaging challenge EUS?","authors":"Peng Wu, Wenxin Zhang, Tingting Wang, Lixue Xu, Zhihua Ren, Yi Li, Yang Xia, Jian Zhu, Qi Liu, Shen Pan, Kai Zhang, Siyu Sun","doi":"10.1097/eus.0000000000000151","DOIUrl":"10.1097/eus.0000000000000151","url":null,"abstract":"<p><strong>Background and objectives: </strong>EUS is widely used in diagnosing and treating digestive system diseases. However, its diagnostic accuracy is frequently compromised by physiological motion from respiration and cardiac activity, as well as interference from gas. To address these limitations, we developed a wireless endoscopic magnetic resonance imaging (EndoMRI) system with balloon-assisted stabilization technology.</p><p><strong>Methods: </strong>The system features a novel wireless EndoMRI coil that uses inductive coupling technology, designed to operate through standard endoscopic working channels. An inflatable balloon with an adjustable diameter range of 10-35 mm maintains optimal coil positioning within the digestive tract. System performance was evaluated using <i>ex vivo</i> porcine esophageal specimens (<i>n</i> = 5) at 5.0T magnetic field strength. Comparative analysis with miniprobe EUS encompassed image quality assessment and histopathological correlation.</p><p><strong>Results: </strong>The results demonstrated that EndoMRI achieved superior esophageal image stability compared to EUS microprobes (<i>P</i> < 0.05). In a thermal injury model, EndoMRI signal continuity showed a strong correlation with histopathological findings of tissue damage, enabling accurate assessment of both lesion depth and severity. The wireless balloon-equipped EndoMRI system provides stable and reliable continuous imaging of <i>ex vivo</i> esophagi.</p><p><strong>Conclusions: </strong>These findings establish EndoMRI as a promising technology in digestive system evaluation.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"14 6","pages":"351-356"},"PeriodicalIF":4.7,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146045815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative EUS-guided biopsy does not affect survival in patients with pancreatic cancer: A nationwide cohort study.","authors":"Bojan Kovacevic, Claus Fristrup, Carsten P Hansen, Michael B Mortensen, Frank Mortensen, Jakob Kirkegård, Mogens T Stender, Sönke Detlefsen, Peter Vilmann","doi":"10.1097/eus.0000000000000156","DOIUrl":"10.1097/eus.0000000000000156","url":null,"abstract":"<p><strong>Background and objectives: </strong>Pancreatic cancer is a highly aggressive malignancy with poor prognosis. Surgery is the only curative treatment, but it carries a significant risk of morbidity. The role of preoperative EUS-guided biopsy (EUS-B) in up-front resectable patients has been a matter of debate, with some centers strongly advocating its use, whereas others limit it to indeterminate cases.We aimed to examine whether preoperative EUS-guided biopsy (EUS-B) has an impact on overall survival (OS) using nationwide data.</p><p><strong>Methods: </strong>The data of patients who underwent curatively intended surgical resection for pancreatic cancer were retrieved from the prospectively maintained national Danish Pancreatic Cancer Group database. Associations between preoperative EUS-B and survival were evaluated using Kaplan-Meier plots and univariable and multivariable Cox proportional hazards models. OS was examined in the overall cohort and in a propensity score-matched subgroup, where EUS-B cases were matched to controls in a 1:2 ratio.</p><p><strong>Results: </strong>Between 2011 and 2023, 1889 patients who underwent surgery for pancreatic cancer constituted the overall cohort. The mean age was 67.4 (SD, 9.1) years, and 53.5% were male. The median overall survival was 28.5 months in the EUS-B group compared to 26.7 months in the non-EUS-B group (HR, 1.07; 95% CI, 0.91-1.26; <i>P</i> = 0.411). In the propensity score-matched subgroup (<i>n</i> = 582), the median survival time was 28.6 months (EUS-B group) and 24.7 months (non-EUS-B group; HR, 1.04; 95% CI, 0.84-1.29; <i>P</i> = 0.691).</p><p><strong>Conclusions: </strong>Preoperative EUS-B did not influence survival in patients with pancreatic cancer in this nationwide retrospective study.</p>","PeriodicalId":11577,"journal":{"name":"Endoscopic Ultrasound","volume":"14 6","pages":"328-333"},"PeriodicalIF":5.4,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12829701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146050984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}