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[[The Pathogenetic Approaches to the Chronic Liver Diseases Treatment].] 慢性肝病的病因学治疗方法[j]。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
E V Golovanova
{"title":"[[The Pathogenetic Approaches to the Chronic Liver Diseases Treatment].]","authors":"E V Golovanova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper reflects the issues of pathogenesis of the chronic liver diseases (CLD). The role of the cell membrane lipid peroxidation as well as oxidative stress and fibrosis formation in the development and progression of liver lesions of various aetiologies. are represented in details. Particular attention is given to the justification of pathogenetic approaches to the treatment of liver disease. Presented the evidence base of successful application of the standardized silymarin as a part of the drug Legalon in the CLD of different etiology.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 5","pages":"65-73"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35089327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[COMORBIDITY AND POLYMORBIDITY IN ADULTS AND CHILDREN IN THE LIGHT OF THE PROBLEM OF NSAID-GASTROPATHY]. [在非甾体类药物胃病的问题下，成人和儿童的共病和多病]。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
Y U S Serebrova, A B Prokofiev, M V Zhuravleva, I B Sichinava, E A Smolyarchuk, P L Galstyan, D O Kurguzova, N A Pankratova
{"title":"[COMORBIDITY AND POLYMORBIDITY IN ADULTS AND CHILDREN IN THE LIGHT OF THE PROBLEM OF NSAID-GASTROPATHY].","authors":"Y U S Serebrova,&nbsp;A B Prokofiev,&nbsp;M V Zhuravleva,&nbsp;I B Sichinava,&nbsp;E A Smolyarchuk,&nbsp;P L Galstyan,&nbsp;D O Kurguzova,&nbsp;N A Pankratova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most demanded drugs. Paper presents the data review on the drug activity mechanisms, effectiveness, safety, and major drug interactions of NSAIDs at co-morbid conditions in different age groups, as well as measures of prevention of NSAID-gastropathy, which can occur even against the use of small doses of NSAIDs. The existing recommendations on the selection of NSAIDs and the complex therapy with drugs of this pharmacological group are shown in considering the individual characteristics of the patient, the pharmacological properties of drugs, the clinical picture of the disease, the presence of risk factors for adverse reactions and drug interactions.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 6","pages":"80-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36551792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
URGENT COLONOSCOPY IN LOWER INTESTINAL BLEEDING. 下肠出血的紧急结肠镜检查。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
A G Korotkevich, E V Zakharchenko, A S Leont'ev, R A Plyusnin
{"title":"URGENT COLONOSCOPY IN LOWER INTESTINAL BLEEDING.","authors":"A G Korotkevich,&nbsp;E V Zakharchenko,&nbsp;A S Leont'ev,&nbsp;R A Plyusnin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was to compare the diagnostic efficacy and safety of emergency colonoscopy without colon preparation at patients with intestinal bleeding.</p><p><strong>Material and methods: </strong>In a comparative cohort study included 252 patients admitted due to intestinal bleeding in 2006- 2015. 118 men, women 134. The average age was 60.15 ± 15,7 years. Patients with explicit anal / hemorrhoidal bleeding at admission or manifestations of gastroesophageal bleeding were excluded. Randomization was performed by alternating days of hospitalization. In Hospital N~ 29 colonoscopy was performed at admission without prior colon preparation, patients of Hospital N~ 1 performed lavage or enema preparation prior to colonoscopy within 24-48hours of hospitalization.</p><p><strong>Results: </strong>Significant differences in the structure of intestinal bleeding source were identified. In patients without bowel preparation most frequently detected bleeding diverticula and cancer - 17%, ulcerative colitis - 1096, intestinal bleeding - 1696, upper bleeding - 16%. At preliminary colon preparation most often as likely causes bleeding source detected cancers - 22%, ulcerative colitis - 15%, angiodysplasia - 13%. Analysis of the dependence of bleeding sources structure from bowel preparation revealed differences only in women. The number of endoscopic findings at colon preparation was 1.5 times higher versus emergency colonoscopy without colon preparation. The number and structure of the observed changes were significantly different between groups, and depending on the sex of patients. There were no complications.</p><p><strong>Conclusion: </strong>Colonoscopy at intestinal bleeding without colon preparation is safe and highly informative in identifying of.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 8","pages":"51-56"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36198378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NEW OPPORTUNITIES OF THE QUALIFYING ENDOSCOPIC DIAGNOSTICS OF PANCREAS NEOPLASMS. 胰腺肿瘤内镜诊断的新机遇。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
P V Pavlov, S S Pirogov, E S Karpov, V V Sokolov, S O Stepanov
{"title":"NEW OPPORTUNITIES OF THE QUALIFYING ENDOSCOPIC DIAGNOSTICS OF PANCREAS NEOPLASMS.","authors":"P V Pavlov,&nbsp;S S Pirogov,&nbsp;E S Karpov,&nbsp;V V Sokolov,&nbsp;S O Stepanov","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>the aim of study was testing and introduction in clinical practice combination of EUS with sonoelastography, fine-needle biopsy and needle-based confocal laser endomicroscopy in advanced diagnostic of pancreatic disease.</p><p><strong>Materials and methods: </strong>in the period from February 2014 to December 2015, we accumulated experience of EUS-FNA in 72 patients mostly with tumor pathology of the pancreas. In 16 cases we used 19G, in 49-22G, and in 7 patients - 25G needles. In 5 patients we used COOK Echotip Procore needle. In 8 cases we performed confocal laser endomicroscopy through the 19G needle (nCLE) in 3 patients with cystic and in 5 - with solid tumors. In 20 patients, there we used.HITA-CHI-PENTAX sonoelastography was performed.</p><p><strong>Results: </strong>There were no complications in EUS-FNA. In all cases we received pathology verification of disease. nCLE results always confirmed by morphological examination of material. In elastography examination normal pancreatic tissue had a equable green-yellow color, in chronic pancreatitis on the same background there were areas of blue seal parenchyma, in the cases pancreatic adenocarcinoma it was marked predominance of blue color scale, in neuroendocrine tumors - diffuse distribution of green and blue areas. Using nCLE in patients with adenocarcinoma revealed the destruction of certain glands, polymorphic nuclei of epithelial cells, with their enlargement, deformation, loss of polarity. Appliance of Procore needle has its technical features, but allowed us to obtain more material with less bloody - due to fewer number of passes.</p><p><strong>Conclusion: </strong>Thus, our study confirms the effectiveness of EUS-FNA with sonoelastography and nCLE. It defines objectives for improvement and expansion of the range for their clinical use.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 10","pages":"80-85"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36210605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[THE DEFEAT OF BONE TISSUE IN CHILDREN WITH INFLAMMATORY BOWEL DISEASES]. [炎症性肠病儿童骨组织的失败]。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
T V Gabrusskaya
{"title":"[THE DEFEAT OF BONE TISSUE IN CHILDREN WITH INFLAMMATORY BOWEL DISEASES].","authors":"T V Gabrusskaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Article (literature review) is devoted to the actual problem of osteopenia and osteoporosis in children with Crohn's disease and ulcerative colitis</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 2","pages":"70-8"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34468429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The report of the plenary session of the gastroenterological scientific society of Russia and interregional scientific-practical conference dedicated to the 90th birthday anniversary of the outstanding physiologist, academician A. M. Ugolev, and the 80th anniversary of the Tver state medical academy, scientific and practical school for gastroenterologists and therapists]. [俄罗斯胃肠病学科学学会全体会议和区域间科学实践会议的报告，专门纪念杰出生理学家A. M. Ugolev院士90周年诞辰，以及特维尔州医学院，胃肠病学家和治疗师的科学和实践学校80周年]。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
G S Dzhulay
{"title":"[The report of the plenary session of the gastroenterological scientific society of Russia and interregional scientific-practical conference dedicated to the 90th birthday anniversary of the outstanding physiologist, academician A. M. Ugolev, and the 80th anniversary of the Tver state medical academy, scientific and practical school for gastroenterologists and therapists].","authors":"G S Dzhulay","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 3","pages":"70-1"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34641841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HEPATIC SARCOIDOSIS. 肝脏结节病。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
M F Osipenko, N B Voloshina
{"title":"HEPATIC SARCOIDOSIS.","authors":"M F Osipenko,&nbsp;N B Voloshina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sarcoidosis is a multisystemic disease of unknown origin characterized by the formation of non caseating granulomas. Thoracic involvement is the most common presentation; however, sarcoidosis can involve almost any other organ. Liver is one of the most frequently affected organs after lungs and lymph nodes. Microscopic hepatic involvement is common in these patients but is mostly clinically silent. specific symptoms include jaundice and pruritus, mostly from chronic cholestasis. In a significant portion of these patients, macroscopic findings can be detected by ultrasound examination ,abdominal CT or magnetic resonance imaging and these findings may easily be confused with other benign and malignant conditions of the liver. Liver biopsy is usually required to confirm the diagnosis. Not all cases of hepatic sarcoidosis require treatment. For symptomatic patients, the first line treatment includes corticosteroids or ursodeoxycholic acid.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 9","pages":"86-90"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36211840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE LONG - TERM RESULTS OF USEFUL ERADICAION PATIENTS WITH PEPTIC ULSERS (a five-year monitoring). 消化性溃疡患者有效根除的长期结果(5年监测)。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
I V Zverkov, O N Minushkin
{"title":"THE LONG - TERM RESULTS OF USEFUL ERADICAION PATIENTS WITH PEPTIC ULSERS (a five-year monitoring).","authors":"I V Zverkov,&nbsp;O N Minushkin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There was held an useful eradication of Helicobacter Pylon in 20 patients with peptic ulcers (Omeprazole, Clarithromycin and Amoxicillin in normal doses). A five - year monitoring period revealed clinical manifestations of relapse in 50% of cases and endoscopic manifestatiQns in 60% of cases (15% - ulcers and 45% - gastral erosions). Relapse of peptic ulcers was accompanied with change of clinical course, it became oligo- or asymptomatic in 83% of patients. Relapse of peptic ulcers was fixed in 45% of patients (15% - in patients with ulcer and 30% - in patients with gastral erosions), at that, erosions were caused by NSAIDs in a half of cases, accompanied with a weak degree of contamination and inflammation of gastral rnucosa.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 10","pages":"15-18"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36211209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FULMINANT PARACETAMOL HEPATITIS. 暴发性扑热息痛肝炎。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
N B Voloshina, M F Osipenko, N V Litvinova
{"title":"FULMINANT PARACETAMOL HEPATITIS.","authors":"N B Voloshina,&nbsp;M F Osipenko,&nbsp;N V Litvinova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article describes a clinical case of fulminant paracetamoly hepatitis a young woman of 33 years. Fulminant hepatitis has developed as a consequence of uncontrolled reception paracetamol-containing medicines for acute viral infection. Paracetamol poisoning conlirmed at autopsy.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 9","pages":"103-106"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36211839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[GASTROENTEROLOGICAL MASK OF CARDIOVASCULAR DISEASE]. 【心血管病胃肠病学口罩】。
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01
T A Ruzhentsova
{"title":"[GASTROENTEROLOGICAL MASK OF CARDIOVASCULAR DISEASE].","authors":"T A Ruzhentsova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article presents variants of the course of cardiovascular disease under a clinical mask of gastroenterological diseases. The author analyzes the clinical examples of atypical symptoms, discusses the diagnostic errors and shows ways to prevent them.</p>","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":" 6","pages":"114-7"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36552718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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