Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology最新文献_第9页

[[The Pathogenetic Approaches to the Chronic Liver Diseases Treatment].] 慢性肝病的病因学治疗方法[j]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

E V Golovanova

引用次数: 0

[THE DEFEAT OF BONE TISSUE IN CHILDREN WITH INFLAMMATORY BOWEL DISEASES]. [炎症性肠病儿童骨组织的失败]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

T V Gabrusskaya

引用次数: 0

[The report of the plenary session of the gastroenterological scientific society of Russia and interregional scientific-practical conference dedicated to the 90th birthday anniversary of the outstanding physiologist, academician A. M. Ugolev, and the 80th anniversary of the Tver state medical academy, scientific and practical school for gastroenterologists and therapists]. [俄罗斯胃肠病学科学学会全体会议和区域间科学实践会议的报告，专门纪念杰出生理学家A. M. Ugolev院士90周年诞辰，以及特维尔州医学院，胃肠病学家和治疗师的科学和实践学校80周年]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

G S Dzhulay

引用次数: 0

MELD SCORE CORRELATION WITH LABORATORY FINDINGS AND COMPLICATIONS OF HEPATITIS C CAUSED LIVER CIRRHOSIS. Meld评分与实验室检查结果及丙型肝炎肝硬化并发症相关。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

M Mjasnikova, I Rudaka, I Zeltina, S Laivacuma, A Derovs

{"title":"MELD SCORE CORRELATION WITH LABORATORY FINDINGS AND COMPLICATIONS OF HEPATITIS C CAUSED LIVER CIRRHOSIS.","authors":"M Mjasnikova, I Rudaka, I Zeltina, S Laivacuma, A Derovs","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Model for End-Stage Liver Disease (MELD) is a scoring system used to estimate the severity of chronic liver disease. Score is based on objective variables and predicts survival among different populations of patients. Study Aim. The aim of the study was to retrospectively analyze potential connection between MELD score and laboratory findings and complications of hepatitis C caused liver cirrhosis.Materials and methods: A retrospective cross-sectional study based on data from Riga East Clinical University Hospital from the time period of 2010 to 2014 was performed. Original protocol and database were developed with consequential data statistical analysis using IBM SPSS Statistics ver.20.0.Results: In total 221 cirrhosis cases were enrolled in the study. 128 (58%) cases were male and 93 (42%) female. Mean age was 52.7 ± 13.4 years. Statistically significant correlation was found between leukocytes (r = 0.4, p < 0.001), blood urea (r = 0.4, p < 0.001), serum albumin (r = -0.4, p < 0.001), C-reactive protein (r = 0.4, p < 0.001) and MELD score. Higher leukocytes, higher urea, C-reactive protein and lower serum albumin rates give higher MELD score. At the time of hospitalization 208 (94%) of the patients had different complications of liver cirrhosis. Correlation between MELD score varied significantly with esophageal varices (r = 0.2, p < 0.05) and esophageal vein bleeding (r = 0.2, p < 0.05). Results show, if patient is present with esophageal varices and esophageal vein bleeding, MELD score is higher.Conclusion: Patients with higher leukocytes, blood urea nitrogen and lower serum albumin level are presenting higher MELD score. In patients who presented with esophageal varices and esophageal vein bleeding, higher MELD score was observed.","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36598398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[GENETIC PREDISPOSITION TO DEVELOPMENT OF TOXIC HEPATITIS]. [中毒性肝炎的遗传易感性]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

T G Kutlina, R R Galimova, M M Shaymukhametova, G F Muchammadiyeva, A B Bakirov, D O Karimov

引用次数: 0

[THE CLINICAL COURSE OF HEPATITIS C IN CHILDREN WITH DIFFERENT VARIANTS OF THE GENE POLYMORPHISM IL28B]. [il28b基因多态性不同变体儿童的丙型肝炎临床病程]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

I A Matinyan, T B Sentsova, I V Vorozhko, O O Chernyak, T V Strokova, M M G Gapparov

{"title":"[THE CLINICAL COURSE OF HEPATITIS C IN CHILDREN WITH DIFFERENT VARIANTS OF THE GENE POLYMORPHISM IL28B].","authors":"I A Matinyan, T B Sentsova, I V Vorozhko, O O Chernyak, T V Strokova, M M G Gapparov","doi":"","DOIUrl":"","url":null,"abstract":"Aim of investigation: The aim of the research is to study the clinical course of hepatitis C in children with different variants of the gene polymorphism of IL-28B.Materials and methods: We observed 94 children (46 girls and 48 boys) with chronic hepatitis C (CHC) in age from 3 to 17 years (mean age 10 years). There were significant differences in the distribution of allele frequencies in children with chronic hepatitis C and in the population. In children with chronic hepatitis C significantly increased the incidence of the T allele at the locus of the gene IL-28B rs12979860 C>T, which makes it possible to consider it as a predictor of antiviral therapy ineffective.Results: When analyzing the frequency of occurrence of a polymorphic variant T>G [rs8099917] IL-28B gene in children with chronic hepatitis C and healthy children revealed no differences in the distribution of alleles.Conclusion: Personalized approach to the appointment of HCV antiviral therapy in children is to carry out genetic studies to determine on the basis of predictive features of the course of HCV in children during the treatment.","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36598404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[COMORBIDITY AND POLYMORBIDITY IN ADULTS AND CHILDREN IN THE LIGHT OF THE PROBLEM OF NSAID-GASTROPATHY]. [在非甾体类药物胃病的问题下，成人和儿童的共病和多病]。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

Y U S Serebrova, A B Prokofiev, M V Zhuravleva, I B Sichinava, E A Smolyarchuk, P L Galstyan, D O Kurguzova, N A Pankratova

引用次数: 0

[GASTROENTEROLOGICAL MASK OF CARDIOVASCULAR DISEASE]. 【心血管病胃肠病学口罩】。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

T A Ruzhentsova

引用次数: 0

URGENT COLONOSCOPY IN LOWER INTESTINAL BLEEDING. 下肠出血的紧急结肠镜检查。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

A G Korotkevich, E V Zakharchenko, A S Leont'ev, R A Plyusnin

{"title":"URGENT COLONOSCOPY IN LOWER INTESTINAL BLEEDING.","authors":"A G Korotkevich, E V Zakharchenko, A S Leont'ev, R A Plyusnin","doi":"","DOIUrl":"","url":null,"abstract":"The aim of the study was to compare the diagnostic efficacy and safety of emergency colonoscopy without colon preparation at patients with intestinal bleeding.Material and methods: In a comparative cohort study included 252 patients admitted due to intestinal bleeding in 2006- 2015. 118 men, women 134. The average age was 60.15 ± 15,7 years. Patients with explicit anal / hemorrhoidal bleeding at admission or manifestations of gastroesophageal bleeding were excluded. Randomization was performed by alternating days of hospitalization. In Hospital N~ 29 colonoscopy was performed at admission without prior colon preparation, patients of Hospital N~ 1 performed lavage or enema preparation prior to colonoscopy within 24-48hours of hospitalization.Results: Significant differences in the structure of intestinal bleeding source were identified. In patients without bowel preparation most frequently detected bleeding diverticula and cancer - 17%, ulcerative colitis - 1096, intestinal bleeding - 1696, upper bleeding - 16%. At preliminary colon preparation most often as likely causes bleeding source detected cancers - 22%, ulcerative colitis - 15%, angiodysplasia - 13%. Analysis of the dependence of bleeding sources structure from bowel preparation revealed differences only in women. The number of endoscopic findings at colon preparation was 1.5 times higher versus emergency colonoscopy without colon preparation. The number and structure of the observed changes were significantly different between groups, and depending on the sex of patients. There were no complications.Conclusion: Colonoscopy at intestinal bleeding without colon preparation is safe and highly informative in identifying of.","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36198378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

NEW OPPORTUNITIES OF THE QUALIFYING ENDOSCOPIC DIAGNOSTICS OF PANCREAS NEOPLASMS. 胰腺肿瘤内镜诊断的新机遇。

Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology Pub Date : 2016-01-01

P V Pavlov, S S Pirogov, E S Karpov, V V Sokolov, S O Stepanov

{"title":"NEW OPPORTUNITIES OF THE QUALIFYING ENDOSCOPIC DIAGNOSTICS OF PANCREAS NEOPLASMS.","authors":"P V Pavlov, S S Pirogov, E S Karpov, V V Sokolov, S O Stepanov","doi":"","DOIUrl":"","url":null,"abstract":"Objective: the aim of study was testing and introduction in clinical practice combination of EUS with sonoelastography, fine-needle biopsy and needle-based confocal laser endomicroscopy in advanced diagnostic of pancreatic disease.Materials and methods: in the period from February 2014 to December 2015, we accumulated experience of EUS-FNA in 72 patients mostly with tumor pathology of the pancreas. In 16 cases we used 19G, in 49-22G, and in 7 patients - 25G needles. In 5 patients we used COOK Echotip Procore needle. In 8 cases we performed confocal laser endomicroscopy through the 19G needle (nCLE) in 3 patients with cystic and in 5 - with solid tumors. In 20 patients, there we used.HITA-CHI-PENTAX sonoelastography was performed.Results: There were no complications in EUS-FNA. In all cases we received pathology verification of disease. nCLE results always confirmed by morphological examination of material. In elastography examination normal pancreatic tissue had a equable green-yellow color, in chronic pancreatitis on the same background there were areas of blue seal parenchyma, in the cases pancreatic adenocarcinoma it was marked predominance of blue color scale, in neuroendocrine tumors - diffuse distribution of green and blue areas. Using nCLE in patients with adenocarcinoma revealed the destruction of certain glands, polymorphic nuclei of epithelial cells, with their enlargement, deformation, loss of polarity. Appliance of Procore needle has its technical features, but allowed us to obtain more material with less bloody - due to fewer number of passes.Conclusion: Thus, our study confirms the effectiveness of EUS-FNA with sonoelastography and nCLE. It defines objectives for improvement and expansion of the range for their clinical use.","PeriodicalId":11555,"journal":{"name":"Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36210605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0