Emerging Contaminants最新文献

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Occurrence, accumulation and potential toxicity of parent and halogenated polycyclic aromatic hydrocarbons in pooled serum of people in different age groups from four Chinese cities 中国4个城市不同年龄组人群血清中母体和卤代多环芳烃的存在、积累及潜在毒性
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-05-16 DOI: 10.1016/j.emcon.2025.100518
Jiali Han , Junsong Bao , Tianwei Li , Yao Jiang , Yuhao Fan , Junjie Jiang , Jun Jin , Jicheng Hu
{"title":"Occurrence, accumulation and potential toxicity of parent and halogenated polycyclic aromatic hydrocarbons in pooled serum of people in different age groups from four Chinese cities","authors":"Jiali Han ,&nbsp;Junsong Bao ,&nbsp;Tianwei Li ,&nbsp;Yao Jiang ,&nbsp;Yuhao Fan ,&nbsp;Junjie Jiang ,&nbsp;Jun Jin ,&nbsp;Jicheng Hu","doi":"10.1016/j.emcon.2025.100518","DOIUrl":"10.1016/j.emcon.2025.100518","url":null,"abstract":"<div><div>Halogenated polycyclic aromatic hydrocarbons (HPAHs) and polycyclic aromatic hydrocarbons (PAHs) were determined in human serum samples pooled by donor age (&lt;20, 20–29, 30–39, 40–49 and ≥ 50 y). The pooled samples were collected from four Chinese cities, Yantai (Shandong Province), Ganzi (Sichuan Province), Huaihua (Hunan Province), and Lingshui (Hainan Province). The concentrations of HPAHs and PAHs were in the range of 4.26–633 ng/g lipid and 249–1642 ng/g lipid from the different cities. Although the levels of HPAHs in blood samples varied among the populations of the four cities, 1,5-dichloroanthracene (1,5-Cl<sub>2</sub>Ant) was the predominant contributor to HPAHs in the serum samples, accounting for over 85.7 % of its total concentration. Furthermore, 1,5-Cl<sub>2</sub>Ant serum concentrations increased significantly with age. Notably, molecular docking results show that 1,5-Cl<sub>2</sub>Ant not only acquires the ability to bind d-AhR PAS-B domain, but also binds at the similar sites as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benzo[a]pyrene (BaP), suggesting that 1,5-Cl<sub>2</sub>Ant, like TCDD and BaP, may cause a wide variety of toxicity via AhR-mediated signaling pathways. The bioaccumulation potential of 1,5-Cl<sub>2</sub>Ant in the human body and its associated toxicity observed in this study need special attention.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100518"},"PeriodicalIF":5.3,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atmospheric detection, prevalence, transmission, health and ecological consequences of antibiotic resistance genes and resistant bacteria: A comprehensive review 大气检测、流行、传播、健康和生态后果抗生素耐药基因和耐药细菌:综合综述
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-05-13 DOI: 10.1016/j.emcon.2025.100514
Liang Fan , Chun Chen , Haijie Zhang , Yang Zeng , Tiejun Li , Rui Gao , Junling Li , Yanqin Ren , Zhenhai Wu , Fang Bi , Yangxi Chu , Hong Li , Jingnan Hu , Jian Xu , Yisheng Xu
{"title":"Atmospheric detection, prevalence, transmission, health and ecological consequences of antibiotic resistance genes and resistant bacteria: A comprehensive review","authors":"Liang Fan ,&nbsp;Chun Chen ,&nbsp;Haijie Zhang ,&nbsp;Yang Zeng ,&nbsp;Tiejun Li ,&nbsp;Rui Gao ,&nbsp;Junling Li ,&nbsp;Yanqin Ren ,&nbsp;Zhenhai Wu ,&nbsp;Fang Bi ,&nbsp;Yangxi Chu ,&nbsp;Hong Li ,&nbsp;Jingnan Hu ,&nbsp;Jian Xu ,&nbsp;Yisheng Xu","doi":"10.1016/j.emcon.2025.100514","DOIUrl":"10.1016/j.emcon.2025.100514","url":null,"abstract":"<div><div>Globally atmospheric transmission of antibiotic-resistance genes (ARGs) and antibiotic-resistant bacteria (ARB) poses a serious challenge to human health and the environment. Thus, a comprehensive and systematic review was established to focus on the detection and analytical methods, distribution characteristics, transmission mechanisms, potential impact on human health and ecological environment of ARGs and ARB in the atmosphere. Emerging methods, such as machine learning and deep learning in artificial intelligence, as well as isothermal amplification methods, have considerably improved the detection efficiency of ARGs and ARB in the atmosphere, along with conventional methods such as Polymerase chain reaction (PCR), PCR derivative methods, and metagenomic sequencing. ARGs and ARB are widely detected in various atmospheric environment, significantly in hospitals, pharmaceutical factories, animal farms, wastewater treatment plants, municipal solid waste landfills and densely populated indoor environments. They can be transferred over extensive distances in the atmosphere <em>via</em> bioaerosols, with their distribution and survival markedly affected by meteorological and climatic factors as well as air contaminants. The transmissions of ARGs and ARB may alter microbial community structures, impact biodiversity, and enhance human exposure risks via inhalation, skin contact, and ingestion. This review synthesizes ARGs and ARB in the atmosphere and provides scientific evidence for policy development and further research, which should focus on the development of intelligent and accurate detection methods, construction of cross-media transmission mechanism and global model, establishment of global health risk assessment system to face the global challenge of antimicrobial resistance.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100514"},"PeriodicalIF":5.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144089109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Veterinary antibiotics in contaminated animal manure: Fate, removal challenges, and future perspectives on conventional and emerging technologies 受污染动物粪便中的兽医抗生素:命运,去除挑战,以及对传统和新兴技术的未来展望
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-05-12 DOI: 10.1016/j.emcon.2025.100515
Chen Ding , Yun Lang , Liwen Xiao , Xinmin Zhan , Lin Shi
{"title":"Veterinary antibiotics in contaminated animal manure: Fate, removal challenges, and future perspectives on conventional and emerging technologies","authors":"Chen Ding ,&nbsp;Yun Lang ,&nbsp;Liwen Xiao ,&nbsp;Xinmin Zhan ,&nbsp;Lin Shi","doi":"10.1016/j.emcon.2025.100515","DOIUrl":"10.1016/j.emcon.2025.100515","url":null,"abstract":"<div><div>The pollution caused by veterinary antibiotics (VAs) has become a global concern due to their role in promoting antimicrobial resistance in the environment. Animal manure, often referred to as animal slurry, contains substantial amounts of VAs originating from animal urine and feces. Since animal manure is commonly used as a nutrient-rich fertilizer, understanding the degradation of VAs and ensuring their efficient removal are essential for effective manure management. This article critically reviews the emerging technologies effective in VA removal, such as adsorption, membrane separation, advanced oxidation processes, carbonization, and bioelectrochemical systems. While these technologies have been extensively studied for their ability to remove pharmaceuticals from common water and wastewater, their applicability to real manure treatment remains insufficiently explored. This article outlines the challenges associated with each technology, particularly concerning the complex composition of animal manure. It highlights the potential of these technologies as supplementary or post-treatment options to improve VA removal, particularly during periods of high VA usage for therapeutic purposes. Finally, the article offers several recommendations, including advancements in animal manure collection, the importance of VA removal to mitigate antimicrobial resistance, and the potential for integrating multiple technologies to optimize VA removal.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100515"},"PeriodicalIF":5.3,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence and ecotoxicity of cosmetic ingredients in aquatic ecosystems: A narrative review 化妆品成分在水生生态系统中的发生及生态毒性研究进展
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-05-08 DOI: 10.1016/j.emcon.2025.100512
Sandra Mota , Emília Sousa , Maria Teresa Cruz , Isabel Martins de Almeida
{"title":"Occurrence and ecotoxicity of cosmetic ingredients in aquatic ecosystems: A narrative review","authors":"Sandra Mota ,&nbsp;Emília Sousa ,&nbsp;Maria Teresa Cruz ,&nbsp;Isabel Martins de Almeida","doi":"10.1016/j.emcon.2025.100512","DOIUrl":"10.1016/j.emcon.2025.100512","url":null,"abstract":"<div><div>Consumer demand for cosmetic products continues to rise which can pose an environmental risk as cosmetic ingredients can enter aquatic systems through wastewater discharge, consumer behaviors, inadequate environmental policies, and ineffective water treatment processes. This review compiles the evidence regarding the occurrence of cosmetic ingredients in aquatic systems, and their potential toxicity to aquatic life and the associated environmental concerns. Existing research primarily targets exfoliants, ultraviolet (UV) filters, antioxidants, preservatives, fragrances, and solvents, representing less than 1 % of known cosmetic ingredients. Plastic microbeads and preservatives were identified as the predominant ingredients in aquatic environments, primarily in wastewater samples. Many of the identified compounds were reported to exhibit toxicity towards aquatic organisms, namely invertebrates, algae and fish. Among the cosmetic ingredients assessed, octocrylene and ethylhexyl dimethyl <em>p</em>-aminobenzoic acid (UV filters), butylated hydroxytoluene (antioxidant), musk xylene (fragrance), and diethylhexyl phthalate (solvent) exhibited the highest degree of toxicity towards aquatic organisms. Understanding these dynamics is important for devising mitigation strategies on environmental risks and providing knowledge for future research and regulatory endeavors in this field.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100512"},"PeriodicalIF":5.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unleashing the power of receptor-based assay on high-throughput detection: Assessing the feasibility of enzyme-linked immunosorbent assay on large-scale antibiotic monitoring 释放基于受体的检测在高通量检测中的力量:评估酶联免疫吸附法在大规模抗生素监测中的可行性
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-25 DOI: 10.1016/j.emcon.2025.100511
Yun Yang , Jinxin Wang , Lulu Li , Haofei Yang , Yu Quan , Jason Jia Shun Liao , Wei Ouyang , Gang Yu , Li Ling
{"title":"Unleashing the power of receptor-based assay on high-throughput detection: Assessing the feasibility of enzyme-linked immunosorbent assay on large-scale antibiotic monitoring","authors":"Yun Yang ,&nbsp;Jinxin Wang ,&nbsp;Lulu Li ,&nbsp;Haofei Yang ,&nbsp;Yu Quan ,&nbsp;Jason Jia Shun Liao ,&nbsp;Wei Ouyang ,&nbsp;Gang Yu ,&nbsp;Li Ling","doi":"10.1016/j.emcon.2025.100511","DOIUrl":"10.1016/j.emcon.2025.100511","url":null,"abstract":"<div><div>Antibiotics are detected in aquatic environments with heterogeneity in their occurrence and associated risk levels. Thus, high spatiotemporal resolution monitoring in a large scale is essential to better cope with their risks. Mass spectrometry (MS) techniques are sensitive and precise, yet complex, expensive, and time-consuming for antibiotic detection. The enzyme-linked immunosorbent assay (ELISA) is among a mature receptor-based assays that offer a cost-effective alternative and are particularly notable for their high throughput analytical capabilities. However, its high throughput power on environmental monitoring is underutilized. ELISA is remarkably rapid (3800–37,000 tests per day), inexpensive ($1.8 per test, capital costs ranging from $35,000 to $270,000), and ready-to-use (97 commercial kits available) for detecting frequently reported antibiotics. Adopting solid phase extraction decreases their limits of detection to as low as 0.125 ng/L. Their quantification results are robust as they also generally agreed well with those of MS methods. A conservative way at present is to use ELISA for initial screening of large numbers of samples, with subsequent quantification of a small proportion of “positive” samples through MS methods. Yet, the applicability of ELISA can be further improved, such as developing a standardized quantification procedure for ELISA and microfluid chip-based ELISA kits and instruments.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100511"},"PeriodicalIF":5.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial distribution of microplastic pollution and its relation to pollution index-based water quality status in Progo River, Indonesia 印尼Progo河微塑料污染空间分布及其与基于污染指数的水质状况的关系
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-16 DOI: 10.1016/j.emcon.2025.100510
Prieskarinda Lestari, Bayu Dwi Apri Nugroho, Hanggar Ganara Mawandha, Chandra Setyawan, Eka Riskawati, Anggraeni Intan Maharani, Brillian Ravi Alvriano, Dhanny Riski Hutama, Nashita Andjani Ludmila Saraswita
{"title":"Spatial distribution of microplastic pollution and its relation to pollution index-based water quality status in Progo River, Indonesia","authors":"Prieskarinda Lestari,&nbsp;Bayu Dwi Apri Nugroho,&nbsp;Hanggar Ganara Mawandha,&nbsp;Chandra Setyawan,&nbsp;Eka Riskawati,&nbsp;Anggraeni Intan Maharani,&nbsp;Brillian Ravi Alvriano,&nbsp;Dhanny Riski Hutama,&nbsp;Nashita Andjani Ludmila Saraswita","doi":"10.1016/j.emcon.2025.100510","DOIUrl":"10.1016/j.emcon.2025.100510","url":null,"abstract":"<div><div>Progo River, one of the largest rivers on Java Island, serves as the primary source of clean water and irrigation for Central Java and the Special Region of Yogyakarta, Indonesia. Despite its importance, the Progo ranks among the top 20 global plastic-polluted rivers. Therefore, the objectives of this study were 1) to investigate spatial distribution and characteristics of microplastic (MP) pollution in the Progo River, and 2) to examine MP relation to the Nemerow Pollution Index (NPI) based water quality status, 15 physicochemical biological water quality parameters, flow velocity and anthropogenic factors, marking the first comprehensive effort in Indonesia. Water and MP samples were collected simultaneously from eight sampling locations. MP abundance in the Progo River ranged from 75.02 to 435.53 particles/m<sup>3</sup>. The MP characteristics were predominantly large, transparent, film-shaped particles, and identified variably as LDPE, PET, PP, PS, PAA, cellophane. The Pearson Correlation Test results revealed positive correlations between MP abundance and nine water quality parameters (TSS, turbidity, salinity, BOD, COD, phosphate, nitrate, detergent, Cd) and flow velocity. The other six parameters (pH, temperature, TDS, DO, total coliforms, Pb) and two anthropogenic factors (population number and density) were negatively correlated with MP abundance. Notably, DO exhibited a strong and significant negative correlation with MP abundance (<em>r = -0.770, p = 0.043</em>). NPI scores (2.10–16.02) revealed slight to heavy polluted levels in the Progo River and were positively correlated with MP abundance (<em>r=0.336, p=0.461</em>). Multiple Linear Regression analysis (<em>R</em><sup><em>2</em></sup> = <em>0.639</em>) identified flow velocity, BOD, COD, turbidity, total coliform, and population number as significant predictors of MP distribution. These findings emphasize the impact of MP pollution on river water quality status, highlighting the need of a novel approach to incorporate MP pollution in periodic water quality assessment to address ecological risks.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100510"},"PeriodicalIF":5.3,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143882356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occurrence of micropollutants and enterobacteria in Ticino Valley: an insight of water contamination in an agricultural area with highly anthropogenic impact 提契诺山谷微污染物和肠杆菌的发生:对高度人为影响农业区水污染的洞察
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-14 DOI: 10.1016/j.emcon.2025.100509
Aurora Piazza , Francesca Merlo , Aseel AbuAlshaar , Francesca Piscopiello , Federica Maraschi , Alice Bernini , Melissa Spalla , Michela Sturini , Roberta Migliavacca , Giorgio Pilla , Antonella Profumo
{"title":"Occurrence of micropollutants and enterobacteria in Ticino Valley: an insight of water contamination in an agricultural area with highly anthropogenic impact","authors":"Aurora Piazza ,&nbsp;Francesca Merlo ,&nbsp;Aseel AbuAlshaar ,&nbsp;Francesca Piscopiello ,&nbsp;Federica Maraschi ,&nbsp;Alice Bernini ,&nbsp;Melissa Spalla ,&nbsp;Michela Sturini ,&nbsp;Roberta Migliavacca ,&nbsp;Giorgio Pilla ,&nbsp;Antonella Profumo","doi":"10.1016/j.emcon.2025.100509","DOIUrl":"10.1016/j.emcon.2025.100509","url":null,"abstract":"<div><div>This study investigates the groundwater quality of an aquifer located in medium-populated area of the Ticino Valley with strong agricultural vocation. Two monitoring campaigns were carried out according to the phases of rice cultivation (pre- and post-flooding) on the subsurface and surface irrigation network, Ticino River and wastewater effluents, highlighting a diffuse contamination. The isotopic analyses evidenced mixing phenomena, with both contributions from local rainfall and irrigation network. Combining chemical and microbiological approaches, the anthropogenic impact was evaluated by analysing a selection of traditional and emerging pollutants, such as pesticides, antibiotics and hormones, and assessing the extent of enterobacterial contamination and potential antibiotic resistance genes. Most of the investigated contaminants were found in concentrations from 0.1 ng/L to 632 ng/L, with the exception of Glyphosate and AMPA up to 5 and 20 μg/L, respectively. Even at these low concentrations, contamination of water resources is a serious issue because long-term exposure to such pollutants may cause detrimental effects. The most frequently detected pesticide was the fungicide Tricyclazole, while glucocorticoid Dexamethasone was the most frequent steroid hormone. Noteworthy is the ubiquity of Trimethoprim and a recurrent presence of fluoroquinolones. The occurrence of antibiotics at most sites, although at very low levels, is of environmental and public health concern, as they exert a selective pressure on bacterial populations, allowing the development of antibiotic resistant microbes, as highlighted by microbiological investigations. Indeed, a high microbial load was found in both campaigns, in particular in those sampling sites close to wastewater treatment plants, with the β-lactams and quinolones classes of antibiotics as the most affected by the phenomenon of resistance.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100509"},"PeriodicalIF":5.3,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143847815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic resistance occurrence and ecological impact in landfill leachate: A review on compound effect of antibiotics and non-antibiotics 垃圾渗滤液中抗生素耐药性的发生及生态影响:抗生素与非抗生素复合效应研究进展
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-10 DOI: 10.1016/j.emcon.2025.100508
Yongtao Xu , Dan Li , Ying Yuan , Fei Fang , Beidou Xi , Wenbing Tan
{"title":"Antibiotic resistance occurrence and ecological impact in landfill leachate: A review on compound effect of antibiotics and non-antibiotics","authors":"Yongtao Xu ,&nbsp;Dan Li ,&nbsp;Ying Yuan ,&nbsp;Fei Fang ,&nbsp;Beidou Xi ,&nbsp;Wenbing Tan","doi":"10.1016/j.emcon.2025.100508","DOIUrl":"10.1016/j.emcon.2025.100508","url":null,"abstract":"<div><div>Landfilling remains one of the primary methods for managing municipal solid waste (MSW), processing approximately 350 million tons of waste annually. Among the various components of landfill waste, pharmaceuticals and personal care products (PPCPs), including both antibiotics and non-antibiotic compounds, pose significant environmental challenges. Landfill leachate is a highly complex medium, consisting of diverse contaminants such as non-antibiotic pharmaceuticals (average concentration ∼1.74 μg/L), antibiotics (average concentration ∼527 ng/L), heavy metals, dissolved organic matter, and micro/nano-plastics (concentration range 0.64–2.16 mg/L). This unique mixture can alter the native microbial community structure, profoundly impacting antibiotic resistance, potentially disrupting soil and groundwater ecosystems, and threatening ecological balance. Existing research has extensively investigated the composition, physicochemical properties, environmental behavior, and microbial community structure of landfill leachate, leading to significant advancements in the field. However, due to the complexity and large volume of landfill leachate, current risk assessment approaches predominantly rely on conventional pollutant indicators, and most treatment strategies are designed for general contaminants. There is a lack of systematic descriptions that integrate pollutants with their direct impacts on microbial communities. This review focuses on the current pollution status, spatiotemporal trends, interactions, and migration risks of antibiotics and non-antibiotic pollutants in landfill leachate. In particular, we explore the in situ emergence of antibiotic resistance in landfill leachate (rather than the horizontal transfer of antibiotic resistance genes) and examine the influence of various leachate components on antibiotic resistance. By emphasizing the importance of understanding the combined effects of antibiotics and non-antibiotic pollutants in landfill environments, this review highlights the necessity of long-term ecological risk assessments for antibiotic-induced resistance as an emerging contaminant.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100508"},"PeriodicalIF":5.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of anti-androgen cyproterone acetate on sperm characteristics, testosterone level, testicular and liver histology in male goldfish (Carassius auratus) 抗雄激素乙酸环丙孕酮对雄性金鱼精子特征、睾酮水平及睾丸和肝脏组织学的影响
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-04 DOI: 10.1016/j.emcon.2025.100507
Hamed Abdollahpour , Milad Karimzadeh , Naghmeh Jafari Pastaki , Hosseinali Zamani
{"title":"Influence of anti-androgen cyproterone acetate on sperm characteristics, testosterone level, testicular and liver histology in male goldfish (Carassius auratus)","authors":"Hamed Abdollahpour ,&nbsp;Milad Karimzadeh ,&nbsp;Naghmeh Jafari Pastaki ,&nbsp;Hosseinali Zamani","doi":"10.1016/j.emcon.2025.100507","DOIUrl":"10.1016/j.emcon.2025.100507","url":null,"abstract":"<div><div>Cyproterone acetate (CA), a synthetic anti-androgen, was injected intraperitoneally into fish at two doses (5 and 50 mg/kg body weight) to evaluate its effects on physiological, biochemical, and reproductive parameters. A total of 180 fish were divided into three groups: Control (C), low-dose (LCA), and high-dose (HCA), with two replicates per group. Fish were observed daily for behavior, and water quality was controlled throughout the study. After 28-days of exposure, blood samples were collected to analyze plasma biochemical parameters. Sperm motility, concentration, and histological analyses of testes and liver tissues were also conducted. Results showed a significant dose-dependent decrease in cholesterol, triglycerides, and testosterone levels in the CA-treated groups, with the highest reduction observed in the HCA group (P &lt; 0.05). Sperm motility was significantly reduced in the low-dose (66.1 ± 2.2 %) and high-dose (36.5 ± 3.9 %) groups compared to the control group (79.5 ± 2.2 %). Similarly, sperm concentration and motility time were significantly reduced in the CA-treated groups (P &lt; 0.05). The gonadosomatic index (GSI) also decreased significantly in the treated groups, with the HCA group showing the lowest GSI (P &lt; 0.05), indicating impaired gonadal development. Histological analysis of the testes revealed delayed spermatogenesis, with the HCA group predominantly showing immature gonadal stages (Stage II), and a significant reduction in spermatocytes and spermatozoa. Liver histology indicated necrosis, cell death, blood congestion, and vacuolization in both the LCA and HCA groups, particularly at the high dose (P &lt; 0.05), suggesting hepatotoxicity. In conclusion, CA exerted significant endocrine-disrupting effects in fish, impairing sperm motility, gonadal development, and liver function in a dose-dependent manner. The high-dose treatment caused pronounced effects, including hepatocellular injury and a severe decline in reproductive health. These findings highlight the potential risks of cyproterone acetate as an endocrine disruptor and emphasize the importance of its effects on aquatic species, particularly in ecotoxicological assessments.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100507"},"PeriodicalIF":5.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143806784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microplastics in settled indoor dust: Implications for human exposure 室内尘埃中的微塑料:对人体暴露的影响
IF 5.3 2区 环境科学与生态学
Emerging Contaminants Pub Date : 2025-04-04 DOI: 10.1016/j.emcon.2025.100506
Hassan Khalid Ageel, Stuart Harrad, Mohamed Abou-Elwafa Abdallah
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