Emerging Contaminants最新文献

{"title":"Biochemical investigation of association of arsenic exposed polymorphic variants and disease susceptibility","authors":"Syed Muhammad Shoaib ,&nbsp;Samina Afzal ,&nbsp;Muhammad Sajid Hamid Akash ,&nbsp;Kanwal Rehman ,&nbsp;Amjad Hussain ,&nbsp;Ahmed Nadeem ,&nbsp;Asif Shahzad ,&nbsp;Sabry M. Attia","doi":"10.1016/j.emcon.2024.100393","DOIUrl":"10.1016/j.emcon.2024.100393","url":null,"abstract":"<div><p>Our study aimed to establish the association of polymorphic variants and disease susceptibility in arsenic-induced metabolic disorders raised due to the variability of arsenic methylation in human population exposed to arsenic in drinking water. Water samples were systematically collected from various regions of Faisalabad, Pakistan, and subjected to arsenic quantification through inductively coupled plasma emission spectrophotometry (ICP-OES). The groundwater exhibited significantly elevated arsenic concentrations (68.18 ± 21.28 μg/L) in comparison to both water and sanitation agency Faisalabad (WASA)-supplied water (9.81 ± 1.2 μg/L) and locally filtered water (8.12 ± 1.42 μg/L), as determined by one-way ANOVA followed by Bonferroni's post-test at <em>P</em> &lt; 0.05. An association was established between arsenic concentration and the incidence of disease, such as diabetes mellitus. A cohort of 120 participants residing in six areas of District Faisalabad was recruited. Urine and blood specimens were collected for analysis. Urine samples underwent ICP-MS analysis in helium collision mode, utilizing germanium as an internal standard. Blood samples were collected for biomarker assessments, including HbA1c, BUN, creatinine, CRP, ALT, AST, GSH, SOD, and MDA, to investigate the evidence of diabetes mellitus. Urinary arsenic concentrations were found to be considerably higher (<em>P</em> &lt; 0.05) in about 22.50 % of the participants, with a mean value of 68.43 ± 16.73 ppb. Biomarker analysis in these participants revealed mean values for BUN (37.19 ± 2.87 mg/dL), creatinine (2.58 ± 0.18 mg/dL), IL-6 (11.35 ± 6.98 pg/mL), CRP (1.90 ± 0.26 mg/dL), MDA (3.70 ± 0.18 nmol/mL), ALT (40.27 ± 5.41 U/L), and AST (38.92 ± 4.72 U/L). Furthermore, the gender-based analysis indicated the higher levels of DMA, MMA, TAs, and TiAs in males compared to females when urine samples were analyzed with HPLC-ICP-MS. Participants with the positive genotype of GSTM exhibited significantly higher levels of TAs, and TiAs concentration in their urine than those with the null genotype of GSTM. Moreover, participants with positive genotypes for GSTT1 and GSTM1 demonstrated elevated levels of DMA in their urine compared to those with genotypes of GSTT1 (−) and GSTM1 (−), although this difference did not attain statistical significance. Participants with the genotype of GSTT1 (+) displayed a considerably higher secondary methylation index than those with genotype of GSTT1 (−). MMA and DMA levels were found to be correlated with the genotypes of GSTT1 and GSTM1 and the amounts of TAs in urine. In conclusion, our findings suggest a linkage between arsenic methylation, particularly levels of DMA and SMI, and GSTT1 and GSTM1 polymorphisms.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 1","pages":"Article 100393"},"PeriodicalIF":5.3,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000945/pdfft?md5=bdd2304a320d732c5a04ad7ac646ce67&pid=1-s2.0-S2405665024000945-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141845979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-occurrence of microplastics and heavy metals in a freshwater lake system in Indian Himalaya: Distribution and influencing factors","authors":"Sunil Kumar ,&nbsp;Kumar Ajay ,&nbsp;Diptimayee Behera ,&nbsp;Aarif Yaseen ,&nbsp;Balasubramanian Karthick ,&nbsp;Sushma Prasad ,&nbsp;Sami Ullah Bhat ,&nbsp;Arshid Jehangir ,&nbsp;Ambili Anoop","doi":"10.1016/j.emcon.2024.100394","DOIUrl":"10.1016/j.emcon.2024.100394","url":null,"abstract":"<div><p>Microplastic (MP) contamination in freshwater systems is a prevalent and persistent environmental issue, yet their occurrence and distribution remain poorly constrained. The present study examines the MPs abundance in sediment and water samples and factors controlling their distribution in the Manasbal Lake, north-western (NW) Himalaya. Additionally, the study investigates the relationship between heavy metals and the distribution of MPs in sediment, as well as their potential interactions. The MPs counts in lake surface sediment and water samples varied from 840 nkg⁻¹ to 4020 nkg⁻¹ and 13 nL⁻¹ to 89 nL⁻¹, respectively. The MPs distribution in Manasbal Lake exhibited spatial heterogeneity, with the greatest abundance observed in the eastern and northeastern areas near lake inlets. Grain size and land use appear to collectively modulate the variability of MPs in Manasbal Lake sediments. Five main MPs types were identified: beads/pellets, fragments, fibres, foams, and films, with beads being the predominant type. Polypropylene, polyethylene, and polystyrene are the dominant constituents of the observed MPs, with domestic sewage suggested as the predominant source for their abundance in the lake. Furthermore, the contamination factor for heavy metals indicated a high level of lead contamination in surface sediments, while copper and cobalt showed moderate contamination near the lake inlet. The SEM-EDS analysis illustrated the presence of toxic elements such as Hg, Zn, Pb, Cr, Cd, Ni, and Cu to the surface of MPs. This study expands the baseline characterization of MPs in freshwater systems and enhances our understanding of the potential sources and factors influencing MP distribution.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 1","pages":"Article 100394"},"PeriodicalIF":5.3,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000957/pdfft?md5=db40ceae065c50f9a44da8330f7db7d3&pid=1-s2.0-S2405665024000957-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current status and risk assessment of perfluoroalkyl acids in surface water and sediments of the Yellow River in Shandong, China","authors":"Xiubao Wang ,&nbsp;Wenjing Chen ,&nbsp;Qingwei Guo ,&nbsp;Zheng Peng ,&nbsp;Qian Sun ,&nbsp;Chuanming Zhao ,&nbsp;Ruirui Zhang","doi":"10.1016/j.emcon.2024.100391","DOIUrl":"10.1016/j.emcon.2024.100391","url":null,"abstract":"<div><p>The Yellow River is the main source of water for urban and rural area and agricultural irrigation in northern China. Herein, the distribution and risk assessment of perfluoroalkyl acids (PFAAs) were investigated from the Yellow River in Shandong Province, China. The total concentration of PFAAs (∑PFAAs) in surface water and sediments were 37.5–2128 ng/L (mean: 167 ng/L) and not detected−6.95 ng/g dry weight (dw) (mean: 1.02 ng/g dw), respectively. Short-chain PFAAs-perfluorobutanoic acid (PFBA), perfluorohexanoic acid (PFHxA), and perfluorobutane sulfonic acid (PFBS) were the most prevalent PFAAs in surface water. Source analysis showed that firefighting foam (proportion: 31.3 %) and textile treatments and food packaging (proportion: 30.3 %) were the main sources of PFAAs in water. Based on the concentration of PFAAs in water, ecological and potential human health risks were assessed. Perfluorooctanoic acid (PFOA), perfluorononanoate (PFNA), perfluorodecanoate (PFDA) and perfluoroundecanoic acid (PFUnDA) posed nonnegligible ecological risk for some aquatic organisms. Levels of PFAAs (e.g., PFOA, PFNA, and PFDA etc.) in some water samples were higher than the advisory guidelines of PFAAs concentrations in water worldwide, indicating a potential human health risk. Therefore, PFOA, PFNA, PFDA, and PFUnDA are the key focus of pollutants in the water of the Yellow River in Shandong Province, and the standards and limits of these PFAAs in environments including surface water and sediment should be promoted.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 1","pages":"Article 100391"},"PeriodicalIF":5.3,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000921/pdfft?md5=0a7328455dda0bafb1d99cef6281cddd&pid=1-s2.0-S2405665024000921-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emergence of antibiotic resistance due to the excessive use of antibiotics in medicines and feed additives: A global scenario with emphasis on the Indian perspective","authors":"Mithuna R ,&nbsp;Tharanyalakshmi R ,&nbsp;Ishan Jain ,&nbsp;Shivangi Singhal ,&nbsp;Divyanshu Sikarwar ,&nbsp;Sovik Das ,&nbsp;J. Ranjitha ,&nbsp;Devanita Ghosh ,&nbsp;Mohammad Mahmudur Rahman ,&nbsp;Bhaskar Das","doi":"10.1016/j.emcon.2024.100389","DOIUrl":"10.1016/j.emcon.2024.100389","url":null,"abstract":"<div><p>Antibiotics were discovered for medicinal applications, notably in the last century and since then, they have been prevalently employed for prophylactic purposes in various sectors in the last few decades. Due to the non-judicial usage of antibiotics in sectors like agriculture, aquaculture, and animal husbandry, and as therapeutic substances, antibiotics have started to become a nuisance for the environment and human beings. Furthermore, the accumulation of antibiotics in the biosphere has led to the development of antibiotic resistance in microorganisms making it difficult to treat a growing number of infections. Hereafter to understand the holistic picture of the impacts associated with antibiotics on the environment, the evolution of individual antibiotic pathways for therapeutic and non-therapeutic purposes needs to be studied along with their effect on the environment. Most of the recent reviews on antibiotics either concentrate on a particular source, pathway or environmental impact; however, the present state-of-the-art review attempts to summarize and update the possible sources of antibiotics, usage, their impact on humans, and environmental health on a global scale with a special emphasis on India. Also, there is a critical discussion about the various methods employed for the removal of antibiotics from an array of sources, on both water and soil matrix. The review finally emphasize that the implication of stringent regulation and selection of appropriate technology are required to alleviate antibiotics menace from the environment.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100389"},"PeriodicalIF":5.3,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000908/pdfft?md5=b92165a30aa8a976a40531e8b57f6c6f&pid=1-s2.0-S2405665024000908-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141704516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application and efficacy of beidellite clay for the adsorption and detoxification of deoxynivalenol (vomitoxin)","authors":"Johnson O. Oladele,&nbsp;Meichen Wang,&nbsp;Kelly J. Rivenbark,&nbsp;Timothy D. Phillips","doi":"10.1016/j.emcon.2024.100390","DOIUrl":"10.1016/j.emcon.2024.100390","url":null,"abstract":"<div><p>The incidence of mycotoxin occurrence throughout the entire lifespan of some agricultural products could be due to climatic conditions and environmental factors (including high temperature, drought, and heavy rainfall) that enhance growth of fungi. Deoxynivalenol (DON) which is also referred to as vomitoxin is a mycotoxin produced from many Fusarium species. DON ranks high among the prominent mycotoxins in cereal products and is a ubiquitous toxin in livestock feeds. DON's adverse effects present major health challenges in both livestock and humans. The use of natural sorbents including smectite clays, is an economically feasible strategy to mitigate mycotoxin toxicities. Previous studies have demonstrated the potential of edible clays as protective components of human food and animal feed to alleviate toxicity associated with short-term exposure to mycotoxins including DON. Hence, this study was designed to investigate the sorption mechanisms of DON onto the binding surfaces of beidellite clay, assessing essential binding parameters such as enthalpy, free energy, binding capacity, affinity, and plateau surface density. These markers were used to predict availability of DON under the experimental conditions. Furthermore, the protection of beidellite clay against DON-induced toxicity was carried out using living organisms susceptible to DON toxicity, including <em>Hydra vulgaris</em> and <em>Lemna minor</em>. These studies investigated the dose-dependent detoxification of DON by 0.05–2 % inclusion of beidellite. Beidellite exhibited more than 75 % protection in <em>Lemna minor</em> and 53 % in <em>Hydra vulgaris</em> validating that this clay is effective in detoxifying DON. During emergencies, or after disasters, inclusion of edible clay like beidellite in food, water or capsules could reduce bioavailability of DON and halt potential exposures to humans and animals.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100390"},"PeriodicalIF":5.3,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S240566502400091X/pdfft?md5=16129059715bdd05ac03dd2fe6756188&pid=1-s2.0-S240566502400091X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141714658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the environmental impact and risks of organic additives in plastics: A call for sustained research and sustainable solutions","authors":"Zehui Wang ,&nbsp;Gang Liang ,&nbsp;Shanxue Jiang ,&nbsp;Fang Wang ,&nbsp;Haifeng Li ,&nbsp;Bingru Li ,&nbsp;Hong Zhu ,&nbsp;Anxiang Lu ,&nbsp;Wenwen Gong","doi":"10.1016/j.emcon.2024.100388","DOIUrl":"https://doi.org/10.1016/j.emcon.2024.100388","url":null,"abstract":"<div><p>The pervasive use of plastics in modern society necessitates the incorporation of organic additives to enhance their performance. However, the leachability of these additives and their potential adverse effects on environmental and biological health have raised significant concerns. This review provides a comprehensive evaluation of the factors influencing the release of organic additives from plastics and examines their detrimental impacts on organisms and humans. It discusses effective degradation techniques, such as photodegradation and biodegradation, to mitigate these adverse effects. Furthermore, this review explores recent advancements in eco-friendly plastic additives, including bio-based plasticizers, flame retardants, antioxidants, and environmentally friendly non-biobased additives. It highlights their potential as alternatives to traditional additives. This review integrates the latest research findings and emerging trends, underscoring the need for continued research and development of sustainable solutions. It aims to facilitate the transition to environmentally friendly degradation techniques and greener plastic additives. This effort contributes to environmental protection and sustainable development, providing crucial guidance and insights for future research and practical applications.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100388"},"PeriodicalIF":5.3,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000891/pdfft?md5=30b8067a5f66741f010e118448b9961b&pid=1-s2.0-S2405665024000891-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141583441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental genotoxicity assessment of nanoparticles using human airway epithelial model","authors":"Sirirak Hemmaphan ,&nbsp;Kotchapawn Somprasong ,&nbsp;Narisa K. Bordeerat","doi":"10.1016/j.emcon.2024.100386","DOIUrl":"https://doi.org/10.1016/j.emcon.2024.100386","url":null,"abstract":"<div><p>Because of the growing use of nanoparticles (NPs) in manufacturing consumer goods, it is essential to identify new <em>in vitro</em> approaches to assess their toxicity and improve risk assessment. Humans are exposed to NPs from contaminated aerosol via multiple routes, such as inhalation, ingestion, and dermal absorption. Human airway epithelial cells are a promising tool for assessing the genotoxicity of NPs <em>in vitro</em>. This study aims to evaluate the genotoxic effects of titanium dioxide (TiO₂), zinc oxide (ZnO), and silver oxide (AgO) NPs on human bronchial/tracheal epithelial cells (HBTECs) using the comet assay. The exposure duration was set to 24 h, and two- (2D) and three-dimensional (3D) spheroid models were used. The genotoxicity of TiO₂ NPs in 2D and 3D HBTEC cells was not statistically significant based on the concentration points examined <em>in vitro</em>. ZnO NPs at concentrations ranging from 10 to 50 μg/mL, when exposed to 2D HBTEC cultures for 24 h, did not show any genotoxic effects. However, genotoxicity was observed at higher concentrations. In contrast, treatment of 2D HBTEC cultures with AgO NPs increased the percentage of tail DNA damage from 50 to 100 μg/mL in a concentration-dependent manner. Within a controlled laboratory environment, ZnO and AgO NPs exhibited a reduction in the length of the tail in 3D spheroid cells. When evaluating genotoxicity, spheroids (3D) represent <em>in vivo</em>-like cell behavior more accurately than monolayer cultures (2D). Collectively, our findings illustrate the harmful effects of NPs on genetic material and emphasize the significance of employing cell culture models to evaluate the risk of toxicity.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100386"},"PeriodicalIF":5.3,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000878/pdfft?md5=a3503e6b0acd0c962874a059db274da1&pid=1-s2.0-S2405665024000878-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking the potential: A comprehensive review on blast furnace slag and silica analog adsorbents for sustainable industrial and pharmaceutical pollution control and resource utilization","authors":"Qing-Guo Dong ,&nbsp;Jing Li ,&nbsp;Zhi-Qing Kang ,&nbsp;Muhammad Imran Anwar ,&nbsp;Muhammad Asad ,&nbsp;Baoji Miao ,&nbsp;Shuanghu Wang ,&nbsp;Ayesha Younas","doi":"10.1016/j.emcon.2024.100387","DOIUrl":"https://doi.org/10.1016/j.emcon.2024.100387","url":null,"abstract":"<div><p>Blast furnace slag (BFS) is a secondary material generated during the process of producing iron in blast furnaces, prompting scholars to concentrate on its efficient management and broad application for the creation of valuable commodities. This study examines the mineral composition, adsorption characteristics, and utilization of BFS and its silica counterparts. Recent developments in the application of BFS and its functionalized materials for pollution mitigation are examined, specifically concentrating on the elimination of nitrogen, phosphorus, metal ions, pharmaceutical effluents, waste oils, and dye molecules from wastewater. Moreover, these inexpensive adsorbents exhibit significant specific surface areas, possess microporous configurations, and contain alkaline components like calcium oxide, magnesium oxide, and aluminum oxide. This review further elucidates the present state of BFS-based adsorbents in the absorption of acid gases, with a specific focus on CO₂. The problems associated with widespread BFS usage are analyzed, and potential solutions for effective resource utilization are discussed.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100387"},"PeriodicalIF":5.3,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S240566502400088X/pdfft?md5=41d23923a9bc42ffb40b425fb5bbf4ae&pid=1-s2.0-S240566502400088X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genomic insights into resistome, virulome, and mobilome as organic contaminants of ESKAPE pathogens and E. coli recovered from milk, farm workers, and environmental settings in Hainan, China","authors":"Ruochen Hao ,&nbsp;Muhammad Shoaib ,&nbsp;Minjia Tang ,&nbsp;Zongxi Cao ,&nbsp;Guangliang Liu ,&nbsp;Yan Zhang ,&nbsp;Shengyi Wang ,&nbsp;Ruofeng Shang ,&nbsp;Hongjuan Zhang ,&nbsp;Wanxia Pu","doi":"10.1016/j.emcon.2024.100385","DOIUrl":"10.1016/j.emcon.2024.100385","url":null,"abstract":"<div><p>The ESKAPE pathogens and <em>E. coli</em> are of significant public health concern and are listed among the top priorities of the World Health Organization. These pathogens are equally important for animal and public health, but their interaction with animal, human, and environmental aspects needs to be sufficiently studied. We investigated the comprehensive molecular characterization of three ESKAPE pathogens and <em>E. coli</em> recovered from milk, farm workers, and environmental settings in Hainan province. Minimum inhibitory concentration (MIC), extended-spectrum β-lactamase production, and biofilm production were performed per set standard protocols. The isolates were further processed by PCR and sequencing to detect resistome, virulome, and mobilome. The study found four <em>Enterobacteriaceae</em> species (<em>E. coli</em>, n=32; <em>K. pneumoniae</em>, n=13; <em>E. cloacae</em>, n=3; <em>E. aerogenes</em>, n=1) among n=49 bacterial isolates from the study area. Most of the strains exhibited resistance against tetracycline (71.4%), ampicillin (61.2%), florfenicol (44.9%), and ciprofloxacin (42.9%), while none of the strains was resistant against meropenem and amikacin. The MDR and ESBL-production percentages were 55.1% and 34.7 %, respectively. The resistance determinants for β-lactams (<em>bla</em>_TEM<em>, bla</em>_OXA-2<em>, bla</em>_SHV<em>, bla</em>_CTX-M), aminoglycosides (<em>aac(3ʹ)-IIa</em>), quinolones (<em>qnrB, qnrS</em>), tetracyclines (<em>tetA, tetD</em>), florfenicol (<em>floR</em>), sulfonamides (<em>sul1</em>, <em>sul2</em>), trimethoprim (<em>dfrA14</em>), and MDR efflux pumps (<em>oqxA, oqxB</em>) were detected along with diverse plasmid replicon types and integrons (<em>intl3</em>, 55.1%; <em>intl1</em>, 18.4%). The detection of virulence determinants was noted at a higher rate, and most of the strains were identified as biofilm producers by genotype (85.7%). The current study findings revealed diversified resistance and virulence determinants along with mobilome in ESKAPE pathogens and <em>E. coli</em>, which may pose a significant threat to human health through the food chain and environmental exposure and need immediate attention.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100385"},"PeriodicalIF":5.3,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000866/pdfft?md5=769bf4e36a472c5b0e8572c33fa5ea44&pid=1-s2.0-S2405665024000866-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review and assessment of mercury contamination and risk in sediment and food chain near a chlor-alkali plant","authors":"Sedigheh Mohamadi ,&nbsp;Mohsen Saeedi","doi":"10.1016/j.emcon.2024.100384","DOIUrl":"https://doi.org/10.1016/j.emcon.2024.100384","url":null,"abstract":"<div><p>Mercury pollution from a chlor-alkali plant has caused a long-term impact on the northwest of the Persian Gulf. In this article, the history of mercury concentration in Musa estuary, Iran, is summarized from previous research and reports and used to estimate the health risk assessment. Despite the closure of the chlor-alkali plant in 2016, the mercury level in sediments and biota is still higher than the acceptable standards in some parts of the estuary. Mercury concentrations and bioaccumulation in the food chain, including fish, crustaceans, birds, and humans, were evaluated. Health risk assessments indicate that consuming some fish species may put children and adults at risk of mercury exposure. Further study is required to fill the gaps for mercury monitoring and recovery.</p></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"10 4","pages":"Article 100384"},"PeriodicalIF":5.3,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405665024000854/pdfft?md5=6d36d5e426aa4164306b8d2e6b970769&pid=1-s2.0-S2405665024000854-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}