Emerging Contaminants最新文献

{"title":"Transcriptomic and metabolomic analysis reveals hepatic lipid metabolism disruption in Japanese quail under polystyrene microplastics exposure","authors":"Xinxin Zhang,&nbsp;Lingyang Jing,&nbsp;Xiaoqing Pei,&nbsp;Qingyu Zhang,&nbsp;Hongfeng Zhao","doi":"10.1016/j.emcon.2025.100548","DOIUrl":"10.1016/j.emcon.2025.100548","url":null,"abstract":"<div><div>Microplastics (MPs) become a global concern due to their impacts on human and wildlife health. In this study, we attempted to determine the hepatotoxic effects of MPs exposure on birds by using a laboratory model animal-Japanese quail (<em>Coturnix japonica</em>) through integrating transcriptomic and metabolomic analysis. Seven-day old female chicks were exposed to low concentrations (0.02 mg/kg, 0.4 mg/kg) and high concentration (8 mg/kg) polystyrene microplastics (PS-MPs) of environmental relevance in the feed for 35 days. The results showed that 0.02 mg/kg and 0.4 mg/kg PS-MPs exposure caused increasing food and water intake with weight gain and liver lipid droplets accumulation while 8 mg/kg PS-MPs exposure induced decreasing food and water intake with weight loss. Moreover, both microstructural damage and ultrastructural injury indicated liver malfunction by PS-MPs exposure. PS-MPs also led to hepatic oxidative stress. Furthermore, untargeted metabolomic analysis showed lipid metabolism disturbance in the liver of PS-MPs exposure. Transcriptomic results also showed molecular signaling pathway disruption in the liver of PS-MPs exposure. Especially, lipid metabolism including peroxisome proliferator activated receptor (PPAR) signaling pathway, fatty acid oxidation, primary bile acid synthesis and triglyceride metabolism were disrupted by PS-MPs exposure. The present study concluded MPs exposure might have hormetic effects on bird development and it posed risks to bird health with low dose MPs may induce non-alcoholic fatty liver disease while high dose MPs may cause severe histopathological injury and oxidative damage. This study underscored the importance of evaluating the chronic effects of microplastics on birds.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100548"},"PeriodicalIF":6.9,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transformation pathways, detection, removal, and sustainable alternatives of 6PPD and its quinone derivative (6PPDQ): A comprehensive review","authors":"Kavya Somepalli,&nbsp;Gangadhar Andaluri","doi":"10.1016/j.emcon.2025.100547","DOIUrl":"10.1016/j.emcon.2025.100547","url":null,"abstract":"<div><div>N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine (6PPD) is a widely used antioxidant and antiozonant in vehicle tires, commonly used to enhance rubber durability and performance. However, its environmental transformation, particularly into 6PPD-Quinone (6PPDQ) through oxidative processes like ozonation, has emerged as a serious concern due to the acute toxicity in aquatic systems. 6PPDQ has been linked to significant mortality in sensitive fish species, including coho salmon, at 41 ng/L concentrations. This review synthesizes recent advances in the understanding of 6PPD degradation pathways, including ozonation, photodegradation, hydrolysis, microbial metabolism, and atmospheric reactions. This paper systematically examines the formation and characterization of various TPs and outlines the methods used for their detection across water, air, soil, sediments, and biota. It also evaluates the efficiency of treatment approaches such as advanced oxidation processes (AOPs), microbial degradation, adsorption, and membrane technologies for the removal of 6PPDQ from contaminated media. Additionally, emerging research on bio-based, synthetic, and engineered antioxidant alternatives to 6PPD is reviewed, with attention to their environmental compatibility and industrial feasibility. The paper concludes with a comprehensive outline of future research priorities focused on improving analytical detection, understanding long-term environmental fate and toxicity, optimizing treatment technologies, and guiding the development of safer alternatives. Collectively, this review provides a foundation for environmental risk assessment, regulatory policy development, and sustainable innovation in rubber manufacturing.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100547"},"PeriodicalIF":6.9,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tackling per- and polyfluorinated alkyl substances in the North African Environment: Slight progress amidst significant challenges","authors":"Badreddine Barhoumi ,&nbsp;Hassan Alshemmari ,&nbsp;Abdulla M. Al-Rawabdeh ,&nbsp;Lassaad Chouba ,&nbsp;Mohamed Ridha Driss ,&nbsp;Soufiane Touil ,&nbsp;Philippe Bersuder ,&nbsp;Imma Tolosa","doi":"10.1016/j.emcon.2025.100546","DOIUrl":"10.1016/j.emcon.2025.100546","url":null,"abstract":"<div><div>Per- and polyfluoroalkyl substances (PFAS) have attracted global attention due to their persistence, potential for bioaccumulation, and adverse effects on both human health and the environment. However, the extent and implications of PFAS contamination in North Africa remain insufficiently explored. This review addresses this regional knowledge gap by critically evaluating the occurrence, sources, and potential impacts of PFAS in environmental and human matrices across North Africa. Based on a comprehensive review of credible scientific sources, this analysis consolidates evidence of PFAS contamination across various environmental and human matrices. All examined matrices, including water, biota, air, foodstuffs, food packaging materials, and human samples, were contaminated by at least one PFAS compound. Potential sources of PFAS are discussed in relation to the known applications of specific compounds. Although PFAS levels reported in the North African environment are generally lower than those observed in more urbanized and industrialized countries, the findings clearly demonstrate the presence and widespread distribution of PFAS in the region. Notably, fish livers collected from Sudan exhibited the highest PFAS concentrations, with perfluorooctane sulfonic acid (PFOS) levels reaching up to 331 ng g⁻¹ wet weight (ww), substantially exceeding the recommended Environmental Quality Standard (EQS) for PFOS in biota set at 9 ng g⁻¹ ww. Identified sources of PFAS contamination include both industrial activities (e.g., manufacturing discharges, aqueous film-forming foams) and consumer-related sources (e.g., municipal landfills, electronic waste, port operations, and precursor degradation). Although toxicological assessments currently suggest a generally low risk to human and ecological health, this may be due to limited monitoring data rather than an actual absence of PFAS. Overall, this review enhances the regional understanding of PFAS pollution in North Africa, highlights critical data gaps, and outlines priorities for future research and policy development aimed at monitoring, regulating, and mitigating PFAS exposure in the region.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100546"},"PeriodicalIF":6.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gadolinium exposure in Procambarus clarkii: tissue-specific bioaccumulation and oxidative stress responses","authors":"Paolo Pastorino ,&nbsp;Alessandra Maganza ,&nbsp;Camilla Mossotto ,&nbsp;Serena Anselmi ,&nbsp;Francesca Provenza ,&nbsp;Alice Gabetti ,&nbsp;Giuseppe Esposito ,&nbsp;Caterina Faggio ,&nbsp;Antonia Concetta Elia ,&nbsp;Monia Renzi ,&nbsp;Marino Prearo","doi":"10.1016/j.emcon.2025.100544","DOIUrl":"10.1016/j.emcon.2025.100544","url":null,"abstract":"<div><div>Gadolinium (Gd), a rare earth element widely used in medical imaging and industry, is increasingly detected in aquatic environments. This study examines tissue-specific bioaccumulation and antioxidant responses in <em>Procambarus clarkii</em> following exposure to environmentally relevant Gd concentrations (0.1, 1, 10, and 100 μg/L) over 14 days. Bioaccumulation was evident in the gills and hepatopancreas at higher exposure levels (10 and 100 μg/L), whereas muscle concentrations remained below the limit of quantification. Oxidative stress responses varied by tissue, with no clear trend revealed by the non-metric multidimensional scaling (NMDs), suggesting limited antioxidant activation likely due to low Gd accumulation and short exposure duration. However, superoxide dismutase (SOD) activity significantly increased in the gills and hepatopancreas at higher Gd concentrations. In contrast, glutathione peroxidase (GPx) activity showed inconsistent trends, while glutathione S-transferase (GST) activity was elevated in hepatppancreas and muscle only at 0.1 μg/L. Lipid peroxidation was most pronounced in the gills. The Integrative Biomarker Response-Threshold (IBR-T) index revealed low-dose effects consistent with hormetic responses, highlighting biologically relevant alterations observed at the lowest Gd concentrations. These findings suggest that <em>P. clarkii</em> exhibits tissue-specific Gd bioaccumulation and oxidative stress responses, albeit with variable biomarker activation. Further research is needed to assess the long-term effects of Gd exposure in freshwater crustaceans, particularly given rising anthropogenic Gd inputs.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100544"},"PeriodicalIF":5.3,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144695261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anion-mediated pathways in organophosphate degradation in the Oconee River watershed in Georgia","authors":"Grace Stamm ,&nbsp;Gayatri Basapuram ,&nbsp;Srimanti Duttagupta ,&nbsp;Avishek Dutta","doi":"10.1016/j.emcon.2025.100542","DOIUrl":"10.1016/j.emcon.2025.100542","url":null,"abstract":"<div><div>The degradation of organophosphate pesticides in aquatic ecosystems is influenced by various environmental factors. This study investigates the influence of nitrate, sulfate, and phosphate on the degradation of malathion, a commonly used organophosphate pesticide, in the North Oconee River watershed in Georgia. Microcosm experiments were conducted to simulate environmental conditions and assess both microbial and non-microbial transformation pathways. Nitrate, sulfate, and phosphate were found to enhance malathion degradation through microbially mediated oxidative and hydrolytic pathways. The presence of mercuric chloride, which suppressed microbial activity, resulted in slower degradation rates across all conditions, underscoring the pivotal role of microbial communities in pesticide transformation. Non-targeted analyses identified key degradation products, including malaoxon, succinic acid, and diethyl succinate, primarily under nitrate and sulfate conditions, supporting the involvement of these anions in the degradation process. These findings highlight the complex interactions between nutrient dynamics and pesticide persistence, offering valuable insights for sustainable water management and pollution control in agro-impacted freshwater systems.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100542"},"PeriodicalIF":5.3,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular response of Physarum melleum GZ381 to anatase TiO2 nanoparticles: Characteristic and application","authors":"Zhi Zhang ,&nbsp;Cheng Xin Wu ,&nbsp;Qin Hui Lu ,&nbsp;Xiu Yi Liang ,&nbsp;Zhi Cheng Liang ,&nbsp;Yi Yang","doi":"10.1016/j.emcon.2025.100539","DOIUrl":"10.1016/j.emcon.2025.100539","url":null,"abstract":"<div><div>Environmental pollution caused by nano titanium dioxide (nTiO₂) has become an increasingly pressing issue. Investigating environmental organisms capable of tolerating nTiO₂ stress, along with their molecular responses, can help us combat such pollution. In this study, we used multi-omics approaches, genetic manipulation, and physiological and biochemical methods to analyze the responses of <em>Physarum melleum</em> GZ381—which tolerates anatase-type nTiO₂ (nTiO₂-A) approximately 30 nm in size—and its responsive biomolecules. We observed that the primary molecular response characteristic of GZ381 was related to metabolism. Furthermore, we found that GZ381 utilizes circular RNA08121 in a competitive endogenous RNA network to regulate the transcriptional abundance of many metabolism-related genes, facilitating metabolic reprogramming and conferring obvious anti-nTiO₂-A stress capabilities. Based on these findings, we designed mitigation schemes that markedly enhanced the tolerance of various non-tolerant cells to nTiO₂-A of different sizes (approximately 30, 60, and 90 nm) under light and dark conditions. Overall, this study reports some important biomolecules that can enhance cellular nTiO₂-A resistance and may be used to combat such pollution in the future, deepens the understanding of environmental organisms, especially those tolerant to nTiO₂ stress, and provides new inspiration for combating such pollution challenges.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100539"},"PeriodicalIF":5.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salmon as an ecological pathway of contaminants into Alaskan food webs","authors":"Miranda Brohman ,&nbsp;Gretchen H. Roffler ,&nbsp;Dimitrios Giarikos ,&nbsp;David W. Kerstetter ,&nbsp;Amy C. Hirons","doi":"10.1016/j.emcon.2025.100541","DOIUrl":"10.1016/j.emcon.2025.100541","url":null,"abstract":"<div><div>Salmon are important fish taxa for humans and animals in hemiboreal and subarctic ecosystems. The presence of trace elements and their bioaccumulation across a marine food web raises potential health risk concerns associated with human consumption. Sixteen trace element concentrations and their health risk assessments were determined in seven different tissues from two Southeast Alaska salmon species. Chum salmon consistently had higher trace element concentrations which may be attributed to a wider variety of diets, generally longer lifespans, and more ocean time compared to pink salmon. Chum kidney and liver samples exceeded the tolerable daily intake for arsenic, indicating a significant risk to wildlife. However, muscle tissues revealed a low risk for human consumption. The target hazard quotients for chronic toxicological risk of all tissue samples did not exceed the hazardous threshold, and the carcinogenic risk values for arsenic, cadmium, chromium, and lead all indicate a negligible cancer risk from human consumption. These results highlight the critical need for continuous monitoring of trace elements in salmon and the potential implications for both human and animal health.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100541"},"PeriodicalIF":5.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seasonal differences, source, and fate of antibiotics in a plain river network-informed watershed","authors":"Shuting Pang ,&nbsp;Tao Li ,&nbsp;Ye Li ,&nbsp;Yadong Shi ,&nbsp;Donghao Wu ,&nbsp;Ce Wang","doi":"10.1016/j.emcon.2025.100540","DOIUrl":"10.1016/j.emcon.2025.100540","url":null,"abstract":"<div><div>The source apportionment and ecological risk assessment of antibiotics in plain river network areas have become a research hotspot. In this study, the Changxing Plain River Network in the Taihu Lake Basin was chosen as the research area, where the Positive Matrix Factorization (PMF) model was used for source apportionment and the Risk Quotient (RQ) and Hazard Index (HI) method were applied for ecological risk assessment. Seasonal variations revealed that antibiotic concentrations were higher during the dry season (N.D-138 ng/L) compared to the wet season (N.D ∼ 22 ng/L), with concentrations in the Jiapu River significantly exceeding those in the other three rivers. PMF model identified four major pollution sources: aquaculture (11 %), diffuse pollution (42 %), urban sewage (30 %), and agriculture (17 %), with diffuse pollution being the largest contributor to antibiotic pollution. Antibiotic flux calculations indicated that the Jiapu River contributed the highest antibiotic load to Taihu Lake, followed by the Changxing River. Ecological risk analysis based on RQ values revealed that erythromycin (ERY), sulfamethoxazole (SMX), and enrofloxacin (ENO) posed moderate risks during the dry season. This study underscores the impacts of various human activities on riverine antibiotic emissions; highlights the need for effective regulation of urban and diffuse pollution; and provides a scientific basis for the formulation of pollution prevention strategies for antibiotic management in Taihu Lake.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100540"},"PeriodicalIF":5.3,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144517488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling the presence of toxic transformation products and microfibers on end-of-life RO membranes","authors":"M.K. Akhil Nazim ,&nbsp;Amitha Unnikrishnan ,&nbsp;Anastasia Penkova ,&nbsp;Charuvila T. Aravindakumar ,&nbsp;Usha K. Aravind","doi":"10.1016/j.emcon.2025.100538","DOIUrl":"10.1016/j.emcon.2025.100538","url":null,"abstract":"<div><div>Point-of-use (PoU) drinking water treatment systems using reverse osmosis (RO) are becoming increasingly popular. Over time, the membrane cartridges in these systems accumulate a concentrated layer of contaminants on their surfaces. This study focuses on analysing this fouling layer by performing autopsies on spent membrane cartridges from PoU units. Four used RO membranes were collected from rural and urban locations in Kerala, India. Two of these membranes treated groundwater in rural areas, while the other two were supplied by municipal water and groundwater in urban settings. The foulants desorbed from the membrane surfaces were analysed using a combination of spectroscopic, microscopic, and chromatographic methods. Non-target analysis (NTA) revealed the presence of micropollutants, including herbicides, personal care products, and pharmaceuticals. Toxic transformation products of diuron, namely 3,4-dichloroaniline and 3,4-dichlorophenyl-N-methylurea, were also detected. Raman spectroscopy identified polyethylene terephthalate (PET) and cotton microfibers, while inorganic foulants such as calcium, iron, silicon, and aluminium were also found. Infrared spectra confirmed that the membranes were composed of polypropylene, polysulfone, and polyurethane. Improper disposal of these end-of-life membranes risks reintroducing these contaminants into the environment.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100538"},"PeriodicalIF":5.3,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the influence of redox and temperature variations on the attenuation of pharmaceuticals in groundwater: Insights from parallel batch reactor experiments","authors":"Alejandra Villa ,&nbsp;Nafiseh Salehi Siavashani ,&nbsp;Estanislao Pujades-Garnes ,&nbsp;Nicola Montemurro ,&nbsp;Sandra Pérez ,&nbsp;Jan Willem Foppen ,&nbsp;Marc Teixidó ,&nbsp;Anna Jurado","doi":"10.1016/j.emcon.2025.100537","DOIUrl":"10.1016/j.emcon.2025.100537","url":null,"abstract":"<div><div>Pharmaceuticals are present in the environment from anthropogenic pollution sources, leading to groundwater contamination when reaching urban aquifers. Once in the subsurface, their fate depends on the hydrochemical processes and environmental conditions within the aquifer. In this context, this study investigates how different redox and temperature conditions affect the natural attenuation of pharmaceuticals in the subsurface. Batch experiments were conducted under oxic and suboxic (i.e., up to nitrate reduction) conditions and at two temperatures (25 °C and 35 °C). The controlled conditions achieved with parallel batch reactor systems allowed us a systematic investigation of the processes and factors involved in the fate of ten pharmaceuticals (atenolol, citalopram, climbazole, irbesartan, lamotrigine, sitagliptin, carbamazepine, metoprolol, trimethoprim, and venlafaxine), providing insights into the mechanisms governing their attenuation. The results showed that oxic conditions were highly effective in reducing pharmaceuticals concentrations, achieving up to 91 % attenuation for irbesartan, followed by citalopram (90 %), climbazole (77 %), sitagliptin (76 %) and metoprolol (75 %). Atenolol and climbazole were also attenuated regardless of redox conditions. High temperatures increased the total removal of citalopram, irbesartan, sitagliptin, and trimethoprim by 5–12 %, while slightly enhancing the sorption affinity of carbamazepine, irbesartan, and atenolol by 5 %. However, trimethoprim, carbamazepine, and lamotrigine were the most persistent compounds, with average removal rates of 6 %, 15 %, and 24 %, respectively. Overall, more than half of the targeted pharmaceuticals showed significant average removal (&gt;60 %), highlighting the influence of the processes involved in groundwater on the natural attenuation of these compounds. Sorption seemed to be the primary process contributing to the target pharmaceuticals attenuation in oxic conditions, while biodegradation played a secondary role, particularly for atenolol and metoprolol. These findings contribute to improve our understanding of the behaviour of pharmaceuticals in aquatic environment and thus to improve management practices for better water quality.</div></div>","PeriodicalId":11539,"journal":{"name":"Emerging Contaminants","volume":"11 3","pages":"Article 100537"},"PeriodicalIF":5.3,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144522280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}