EndoscopyPub Date : 2026-10-20DOI: 10.1055/a-2960-1308
Georgios Kalopitas, Elisabet Maristany Bosch, Michael Spiro, Hironori Yamamoto, Alberto Murino, Edward John Despott
{"title":"Hypothermia: mitigating a hidden procedural risk of saline-immersion/irrigation endoscopic submucosal dissection.","authors":"Georgios Kalopitas, Elisabet Maristany Bosch, Michael Spiro, Hironori Yamamoto, Alberto Murino, Edward John Despott","doi":"10.1055/a-2960-1308","DOIUrl":"https://doi.org/10.1055/a-2960-1308","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149227388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-19DOI: 10.1055/a-2944-4098
Mayan Eitan, Sunil Gupta, Jun Young Kim, Yong Sul Kim, Charlene Deane, Albert Jeroen De Groof, Stephen Williams, Eric Y Lee, Brian Lam, Nicholas G Burgess, Michael J Bourke
{"title":"Prophylactic clip closure after right-colon endoscopic mucosal resection in a matched cohort of 470 patients exhibits subsite heterogeneity.","authors":"Mayan Eitan, Sunil Gupta, Jun Young Kim, Yong Sul Kim, Charlene Deane, Albert Jeroen De Groof, Stephen Williams, Eric Y Lee, Brian Lam, Nicholas G Burgess, Michael J Bourke","doi":"10.1055/a-2944-4098","DOIUrl":"10.1055/a-2944-4098","url":null,"abstract":"<p><strong>Background: </strong>Clinically significant post-endoscopic mucosal resection (EMR) bleeding (CSPEB) is the most common adverse event after EMR of large nonpedunculated colorectal polyps (LNPCPs). Randomized trials of prophylactic through-the-scope (TTS) clip closure have produced conflicting results, and it remains unclear whether the effect is uniform across right-colon subsites and whether complete apposition is required. We examined real-world outcomes of a universal right-colon clipping policy, with attention given to subsite heterogeneity and closure completeness.</p><p><strong>Methods: </strong>Consecutive patients who underwent EMR of right-sided LNPCPs ≥20 mm (January 2020-October 2025) with prophylactic TTS clip closure were identified from the prospectively maintained ACE (Australian Colonic Endoscopic resection) registry, and matched 1:1 by propensity score to a no-clip comparator from the same registry (pre-2020). The primary end point was CSPEB within 14 days; subsite heterogeneity and closure completeness were exploratory analyses.</p><p><strong>Results: </strong>Propensity score matching yielded 235 matched pairs (n = 470), who were well balanced on all covariates. CSPEB occurred in 8/235 clipped (3.4%) versus 26/235 unclipped patients (11.1%; relative risk 0.31, 95%CI 0.14-0.66; number needed to treat 13; <i>P</i> = 0.002). Exploratory subsite analyses suggested benefit concentrated at the hepatic flexure (0% vs. 17.2%; <i>P</i> = 0.02) and ascending colon (2.0% vs. 10.1%; <i>P</i> = 0.03), with a nonsignificant difference at the cecum (8.2% vs. 13.7%; <i>P</i> = 0.43). Within the clipped cohort, CSPEB rates were similar with complete (5/143; 3.5%) and partial (3/92; 3.3%) closure (<i>P</i> > 0.99).</p><p><strong>Conclusion: </strong>In this single-center analysis, TTS clip closure was associated with lower CSPEB after right-colon EMR, especially at the hepatic flexure and ascending colon; partial apposition appeared as effective as complete closure. These hypothesis-generating observations warrant prospective evaluation.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-19DOI: 10.1055/a-2971-3992
Hinrich Fehrendt, Hauke Hamel, Franziska Halfmann, Nikolaus Schäfer, Maximilian Bockhorn, Christian Meinhardt, Mark Ellrichmann
{"title":"Sweet relief-endoscopic ultrasound-guided jejunojejunostomy using a lumen-apposing metal stent for candy cane syndrome.","authors":"Hinrich Fehrendt, Hauke Hamel, Franziska Halfmann, Nikolaus Schäfer, Maximilian Bockhorn, Christian Meinhardt, Mark Ellrichmann","doi":"10.1055/a-2971-3992","DOIUrl":"https://doi.org/10.1055/a-2971-3992","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149223555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-16DOI: 10.1055/a-2953-9044
Leon M G Moons
{"title":"Beyond surface assessment: the emerging role of deep-margin optical diagnosis in early rectal cancer.","authors":"Leon M G Moons","doi":"10.1055/a-2953-9044","DOIUrl":"https://doi.org/10.1055/a-2953-9044","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-16DOI: 10.1055/a-2885-8416
Rui Wang, Shiqin Huang, Xiaoyan Wang
{"title":"A voice-guided real-time artificial intelligence system for navigation and quality control during standardized mediastinal endosonography scanning.","authors":"Rui Wang, Shiqin Huang, Xiaoyan Wang","doi":"10.1055/a-2885-8416","DOIUrl":"https://doi.org/10.1055/a-2885-8416","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-16DOI: 10.1055/a-2955-8529
Masau Sekiguchi, Marcus Westerberg, Anna Andreasson, Soran R Bozorg, Anna M Forsberg
{"title":"Serrated polyp detection rates beyond adenoma detection rate for postcolonoscopy colorectal cancer: findings from the SCREESCO trial.","authors":"Masau Sekiguchi, Marcus Westerberg, Anna Andreasson, Soran R Bozorg, Anna M Forsberg","doi":"10.1055/a-2955-8529","DOIUrl":"https://doi.org/10.1055/a-2955-8529","url":null,"abstract":"<p><strong>Background: </strong>The association between serrated polyp detection rates, including proximal serrated polyp detection rate (PSPDR), and postcolonoscopy colorectal cancer (PCCRC) remains unestablished. We investigated PCCRC incidence and characteristics, and explored associations of PSPDR and adenoma detection rate (ADR) with PCCRC in colonoscopy- and fecal immunochemical test (FIT)-based screening within the Screening of Swedish Colons (SCREESCO) trial.</p><p><strong>Methods: </strong>Data from participants who underwent colonoscopy in the colonoscopy and FIT arms were analyzed. PCCRC, defined as colorectal cancer (CRC) diagnosed >6 months after a colonoscopy that did not detect CRC, was identified through linkage with cancer registries. Associations between PSPDR and PCCRC incidence were assessed using Cox models.</p><p><strong>Results: </strong>Of 9982 and 5875 individuals in the colonoscopy and FIT arms, PCCRC was identified in 20 and 17 individuals, with 3-year PCCRC rates of 5.9% (3/51) and 3.5% (4/115), respectively. Compared with screening-detected CRC, PCCRC more often involved right-sided location and advanced stage. The 5-year cumulative incidence of PCCRC was 0.16% (95%CI 0.10%-0.27%) and 0.06% (95%CI 0.02%-0.15%) when colonoscopies were performed by endoscopists with low vs. high PSPDR (<10% vs. ≥10%), respectively. Among endoscopists with high ADR, 5-year PCCRC incidence was 0.13% (95%CI 0.04%-0.32%) vs. 0.06% (95%CI 0.02%-0.16%) for those with low vs. high PSPDR, respectively. Within this group, PCCRC incidence over 8 years decreased as PSPDR increased (hazard ratio per percentage-point increase, 0.90; 95%CI 0.82-1.00; P = 0.04).</p><p><strong>Conclusions: </strong>Despite the limited number of PCCRC events, this study suggests that PSPDR provides complementary information beyond ADR for identifying colonoscopies with higher PCCRC incidence.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2026-10-16DOI: 10.1055/a-2975-4821
Hanne Hellinckx, Michiel Bronswijk, Gitte Aabye Olsen, Giuseppe Vanella, Hanna Peeters, Marie-Anne Noreillie, Francesco Frigo, Roberto Leone, Hannah van Malenstein, Wim Laleman, Rogier Voermans, Paolo Giorgio Arcidiacono, Halit Topal, Baki Topal, Roy L J van Wanrooij, Schalk Van der Merwe
{"title":"Predictors of clinical success in endoscopic ultrasound-guided drainage of postoperative pancreatic fluid collections.","authors":"Hanne Hellinckx, Michiel Bronswijk, Gitte Aabye Olsen, Giuseppe Vanella, Hanna Peeters, Marie-Anne Noreillie, Francesco Frigo, Roberto Leone, Hannah van Malenstein, Wim Laleman, Rogier Voermans, Paolo Giorgio Arcidiacono, Halit Topal, Baki Topal, Roy L J van Wanrooij, Schalk Van der Merwe","doi":"10.1055/a-2975-4821","DOIUrl":"https://doi.org/10.1055/a-2975-4821","url":null,"abstract":"<p><strong>Background and aims: </strong>Endoscopic ultrasound (EUS)-guided drainage is increasingly used for the management of postoperative pancreatic fluid collections (POPFC). We aimed to identify factors associated with clinical success, and to perform exploratory analyses of outcomes stratified by surgery type and stent type.</p><p><strong>Patients and methods: </strong>We performed a retrospective multicenter cohort study including patients who underwent EUS-guided drainage of POPFC following pancreatic surgery between 2014 and August 2024 at three academic centers. The primary outcome was clinical success, defined as combined radiological and clinical resolution without the need for percutaneous or surgical step-up intervention.</p><p><strong>Results: </strong>A total of 265 patients were included (mean age 64±14 years; 57% male; 52% underwent drainage ≤14 days after surgery, necrotic component in 51%). Clinical success was achieved in 194 patients (73%; 95% CI 67.5-78.1%), including 160 (60%; 95% CI 54.5-66.3%) after a single procedure and 34 after additional endoscopic reinterventions, while 20 patients (7.6%; 95% CI 4.4-10.7%) required percutaneous or surgical step-up. Distal pancreatectomy, compared with pancreaticoduodenectomy, was associated with a higher rate of reintervention (32% vs. 20%, p=0.02) and independently associated with lower odds of clinical success (odds ratio 0.53, 95% confidence interval 0.29-0.98; p=0.04).</p><p><strong>Conclusions: </strong>EUS-guided drainage for POPFC appears effective, with an acceptable safety profile in expert centers, achieving clinical resolution in the majority of patients. Distal pancreatectomy was associated with a more complex treatment course. These findings support the use of EUS-guided drainage as a central component in the management of POPFC.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":""},"PeriodicalIF":11.8,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149206581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}