EndoscopyPub Date : 2025-01-01Epub Date: 2024-09-03DOI: 10.1055/a-2382-5795
Carlos Fernandes, Manuela Estevinho, Manuel Marques Cruz, Leonardo Frazzoni, Pedro Pereira Rodrigues, Lorenzo Fuccio, Mário Dinis-Ribeiro
{"title":"Adenoma detection rate by colonoscopy in real-world population-based studies: a systematic review and meta-analysis.","authors":"Carlos Fernandes, Manuela Estevinho, Manuel Marques Cruz, Leonardo Frazzoni, Pedro Pereira Rodrigues, Lorenzo Fuccio, Mário Dinis-Ribeiro","doi":"10.1055/a-2382-5795","DOIUrl":"10.1055/a-2382-5795","url":null,"abstract":"<p><strong>Background: </strong>Adenoma detection rate (ADR) is a quality indicator set at a minimum of 25% in unselected populations by the European Society of Gastrointestinal Endoscopy (ESGE). Nevertheless, a lack of pooled observational data resembling real-world practice limits support for this threshold. We aimed to perform a systematic review with meta-analysis to evaluate the pooled rates for conventional adenoma detection, polyp detection (PDR), cecal intubation, bowel preparation, and complications in population-based studies.</p><p><strong>Methods: </strong>The PubMed, Scopus, and Web of Science databases were searched until May 2023 for populational-based studies reporting overall ADR in unselected individuals. A random-effects model was used for meta-analysis.</p><p><strong>Results: </strong>31 studies were included, comprising 3 644 561 subjects. A high quality of procedures was noticeable, with a high cecal intubation rate and low complication rate. The overall pooled ADR, PDR, and rate of cancer detection were 26.5% (95%CI 23.3% to 29.7%), 38.3% (95%CI 32.5% to 44.1%), and 2.7% (95%CI 1.5% to 3.9%), respectively. ADR varied according to indication: screening 33.3% (95%CI 24.5% to 42.2%), surveillance 42.9% (95%CI 36.9% to 49.0%), and diagnostic 24.7% (95%CI 19.5% to 29.9%), with subgroup analysis revealing rates of 34.4% (95%CI 22.0% to 40.5%) for post-fecal occult blood test and 26.6% (95%CI 22.6% to 30.5%) for primary colonoscopy screening. Diminutive conventional adenomas yielded a pooled rate of 59.9% (95%CI 43.4% to 76.3%). The pooled rate for overall serrated lesion detection was 12.4% (95%CI 8.8% to 16.0%). Male sex and higher age were significantly associated with an ADR above the benchmark.</p><p><strong>Conclusion: </strong>This first meta-analysis relying on real-world observational studies supports the ESGE benchmark for ADR, while suggesting that different benchmarks might be used according to indication, sex, and age.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"49-61"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-08-29DOI: 10.1055/a-2378-1464
Umair Kamran, Felicity Evison, Eva Judith Ann Morris, Matthew J Brookes, Matthew David Rutter, Mimi McCord, Nicola J Adderley, Nigel Trudgill
{"title":"The variation in post-endoscopy upper gastrointestinal cancer rates among endoscopy providers in England and associated factors: a population-based study.","authors":"Umair Kamran, Felicity Evison, Eva Judith Ann Morris, Matthew J Brookes, Matthew David Rutter, Mimi McCord, Nicola J Adderley, Nigel Trudgill","doi":"10.1055/a-2378-1464","DOIUrl":"10.1055/a-2378-1464","url":null,"abstract":"<p><strong>Background: </strong>Post-endoscopy upper gastrointestinal cancer (PEUGIC) is an important key performance indicator for endoscopy quality. We examined variation in PEUGIC rates among endoscopy providers in England and explored associated factors.</p><p><strong>Methods: </strong>The was a population-based, retrospective, case-control study, examining data from National Cancer Registration and Analysis Service and Hospital Episode Statistics databases for esophageal and gastric cancers diagnosed between 2009 and 2018 in England. PEUGIC were cancers diagnosed 6 to 36 months after an endoscopy that did not diagnose cancer. Associated factors were identified using multivariable logistic regression analyses.</p><p><strong>Results: </strong>The national PEUGIC rate was 8.5%, varying from 5% to 13% among endoscopy providers. Factors associated with PEUGIC included: female sex (odds ratio [OR] 1.29 [95%CI 1.23-1.36]); younger age (age >80 years, OR 0.52 [0.48-0.56], compared with ≤60 years); increasing comorbidity (Charlson score >4, OR 5.06 [4.45-5.76]); history of esophageal ulcer (OR 3.30 [3.11-3.50]), Barrett's esophagus (OR 3.21 [3.02-3.42]), esophageal stricture (OR 1.28 [1.20-1.37]), or gastric ulcer (OR 1.55 [1.44-1.66]); squamous cell carcinoma (OR 1.50 [1.39-1.61]); and UK national endoscopy accreditation status - providers requiring improvement (OR 1.10 [1.01-1.20]), providers never assessed (OR 1.24 [1.04-1.47]).</p><p><strong>Conclusion: </strong>PEUGIC rates varied threefold among endoscopy providers, suggesting unwarranted differences in endoscopy quality. PEUGIC was associated with endoscopy findings known to be associated with upper gastrointestinal cancer and a lack of national endoscopy provider accreditation. PEUGIC variations suggest an opportunity to raise performance standards to detect upper gastrointestinal cancers earlier and improve outcomes.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"17-28"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142105473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-09-03DOI: 10.1055/a-2386-9098
Adolfo Parra-Blanco
{"title":"Overtubes: a bridge to successful colonoscopic resection?","authors":"Adolfo Parra-Blanco","doi":"10.1055/a-2386-9098","DOIUrl":"10.1055/a-2386-9098","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"74-76"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-07-11DOI: 10.1055/a-2350-4059
Salmaan Jawaid, Ahmed F Aboelezz, Gehad Daba, Mai Khalaf, Fares Ayoub, Noor Zabad, Michael Mercado, Tara Keihanian, Mohamed Othman
{"title":"Prospective feasibility study of a novel rigidizing stabilizing overtube in the resection of complex gastrointestinal polyps.","authors":"Salmaan Jawaid, Ahmed F Aboelezz, Gehad Daba, Mai Khalaf, Fares Ayoub, Noor Zabad, Michael Mercado, Tara Keihanian, Mohamed Othman","doi":"10.1055/a-2350-4059","DOIUrl":"10.1055/a-2350-4059","url":null,"abstract":"<p><strong>Background: </strong>A novel rigidizing overtube (ROT) was developed to facilitate endoscopic removal of complex gastrointestinal polyps. We aimed to prospectively evaluate the efficacy and safety of the device in the management of large gastrointestinal polyps.</p><p><strong>Methods: </strong>A prospective, single-center study, conducted between May 2021 and April 2023, enrolled patients undergoing endoscopic resection of colon/duodenal polyps ≥25 mm. Primary outcomes were safety, technical success, and clinical success defined as the ability of ROT to facilitate endoscopic polyp removal without changing the initial resection method.</p><p><strong>Results: </strong>97 patients (98 polyps), with a mean polyp size of 33.2 mm (median 31.1), were evaluated. Technical and clinical success rates were 100% and 84%, respectively. Ileocecal valve location was the only predictor of clinical failure (P = 0.02). The mean time to reach the lesion was 7.2 minutes (95%CI 5-8), with overall resection and procedure times of 53.6 minutes (95%CI 48-61) and 88.9 minutes (95%CI 79-95), respectively. No device-related adverse events occurred. Lower technical (67%) and clinical (67%) success rates were seen for duodenal polyps (n = 6).</p><p><strong>Conclusion: </strong>The novel ROT was safe, with high technical and clinical success during resection of complex colon polyps. Future studies will determine timing of implementation during routine endoscopic resection.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"68-73"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141589938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2368-2271
{"title":"Author commentary on Paula Arruda do Espirito Santo et al.","authors":"","doi":"10.1055/a-2368-2271","DOIUrl":"https://doi.org/10.1055/a-2368-2271","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"v2"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-12-19DOI: 10.1055/a-2438-0202
Yaxian Kuai, Shiwei Zhou, Bin Sun, Xu Wang, Youwei Xiao, Aijiu Wu, Derun Kong
{"title":"Use of an endoscopic virtual ruler based on the fiber laser principle and artificial intelligence technology.","authors":"Yaxian Kuai, Shiwei Zhou, Bin Sun, Xu Wang, Youwei Xiao, Aijiu Wu, Derun Kong","doi":"10.1055/a-2438-0202","DOIUrl":"https://doi.org/10.1055/a-2438-0202","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":"57 1","pages":"86-87"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-10-16DOI: 10.1055/a-2427-7128
Kornpong Vantanasiri, Prasad G Iyer
{"title":"Comparing recurrence rates between endoscopic mucosal resection and endoscopic submucosal dissection in Barrett's endoscopic therapy: timing and definitions matter!","authors":"Kornpong Vantanasiri, Prasad G Iyer","doi":"10.1055/a-2427-7128","DOIUrl":"10.1055/a-2427-7128","url":null,"abstract":"","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"14-16"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142460678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EndoscopyPub Date : 2025-01-01Epub Date: 2024-08-28DOI: 10.1055/a-2368-4608
Paula Arruda do Espirito Santo, Gilmara Coelho Meine, Angélica Luciana Nau, Eduardo Cerchi Barbosa, Stefano Baraldo, Luciano Lenz, Fauze Maluf-Filho
{"title":"Endoscopic ultrasound-guided versus percutaneous liver biopsy: a systematic review and meta-analysis of randomized controlled trials.","authors":"Paula Arruda do Espirito Santo, Gilmara Coelho Meine, Angélica Luciana Nau, Eduardo Cerchi Barbosa, Stefano Baraldo, Luciano Lenz, Fauze Maluf-Filho","doi":"10.1055/a-2368-4608","DOIUrl":"10.1055/a-2368-4608","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous liver biopsy (PC-LB) has long been the usual method for acquisition of liver tissue. Recently, endoscopic ultrasound-guided liver biopsy (EUS-LB) has gained popularity as an alternative modality. We aimed to compare the efficacy and safety of EUS-LB versus PC-LB.</p><p><strong>Methods: </strong>We systematically searched PubMed, Embase, and the Cochrane Library databases for randomized controlled trials (RCTs) comparing EUS-LB with PC-LB published until October 20, 2023. The primary outcome was diagnostic adequacy. Secondary outcomes were: the number of complete portal tracts (CPTs), longest sample length (LSL), total sample length (TSL), post-procedure pain scores, and adverse events (AEs), including overall AEs and AEs excluding minor post-procedure symptoms. We compared binary outcomes using risk ratios (RRs) and continuous outcomes using the mean difference (MD) or standardized mean difference (SMD), with 95%CIs.</p><p><strong>Results: </strong>Four RCTs (258 patients) were included. The EUS-LB group presented lower post-procedure pain scores (SMD -0.58, 95%CI -0.95 to -0.22) than the PC-LB group. Both groups performed similarly in terms of diagnostic adequacy (RR 1.0, 95%CI 0.96 to 1.04), number of CPTs (MD 2.57, 95%CI -4.09 to 9.22), LSL (MD -2.91 mm, 95%CI -5.86 to 0.03), TSL (MD 4.16 mm, 95%CI -10.12 to 18.45), overall AEs (RR 0.54, 95%CI 0.20 to 1.46), and AEs excluding minor post-procedure symptoms (RR 1.65, 95%CI 0.21 to 13.02).</p><p><strong>Conclusions: </strong>This meta-analysis suggests that EUS-LB is as safe and effective as PC-LB and is associated with lower post-procedure pain scores.Registration on PROSPERO: CRD42023469469.</p>","PeriodicalId":11516,"journal":{"name":"Endoscopy","volume":" ","pages":"41-48"},"PeriodicalIF":11.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}