ecancermedicalscience最新文献

{"title":"Feasibility and stage at diagnosis for children with cancer: a pilot study on population-based data in a middle-income country using the Toronto childhood cancer stage guidelines.","authors":"Marceli de Oliveira Santos, Paulo Cesar Fernandes de Souza, Fernanda C da Silva de Lima, Nathalie V Balmant, Carolina Motta, Michele Gonçalves da Costa, Rejane de Souza Reis, Gemma Gatta, Beatriz de Camargo","doi":"10.3332/ecancer.2024.1795","DOIUrl":"10.3332/ecancer.2024.1795","url":null,"abstract":"<p><strong>Background: </strong>The aim was to conduct a pilot study in a middle-income country testing the use of the Toronto Childhood Cancer Staging System by Population-Based Cancer Registry (PBCR).</p><p><strong>Methods: </strong>This study involved first the translation of the Australian pediatric cancer staging manual for 16 types of pediatric tumours. Four PBCRs from different regions of Brazil were selected for a pilot study. The study period was from 2005 to 2014, and data were collected from notification sources, including hospitals, pathological laboratories and routine medical records, and staging was done retrospectively.</p><p><strong>Results: </strong>We identified 1,560 pediatric cancer cases diagnosed between 2005 and 2014. Notably, 94.7% met Tier 1 criteria, and 91.9% met Tier 2 criteria. The PBCR from Curitiba (south region) demonstrated higher staging feasibility (99.3% Tier 1; 96.7% Tier 2) than from Aracaju (northeast) (87.5% Tier 1; 81.3% Tier 2). Most cases had localised or regional disease (77.7%), while 14.3% were metastatic, and 8.0% could not be staged. Osteosarcoma had the highest metastasis rate (50.0%).</p><p><strong>Conclusion: </strong>Our study demonstrates the feasibility of collecting pediatric cancer stage data from population-based registries in resource-limited settings, advancing our understanding of pediatric cancer outcomes in Brazil.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1795"},"PeriodicalIF":1.2,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and predictors of chemotherapy-induced peripheral neuropathy among female breast cancer patients undergoing chemotherapy in Lagos.","authors":"Ademola Oluwatosin Oyekan, Omolara Aminat Fatiregun, Muhammad Habeebu, Ifeanyichukwu Augustine Onyeodi, Adebayo Deborah Adeoluwa","doi":"10.3332/ecancer.2024.1791","DOIUrl":"10.3332/ecancer.2024.1791","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy-induced peripheral neuropathy (CIPN) is a major side effect associated with chemotherapy. It can lead to detrimental dose reductions and discontinuation of treatment because of its significant effect, which impairs the quality of life among the surviving population of cancer patients. This study assesses the prevalence and predictors of CIPN among female breast cancer patients receiving chemotherapy at the Lagos University Teaching Hospital and Lagos State University Teaching Hospital (LUTH and LASUTH), respectively.</p><p><strong>Methods: </strong>261 women with histologically confirmed breast cancer who had just concluded first line chemotherapy were recruited for this study. The relevant data was obtained using a designed/semi-structured questionnaire for patient demographic information, and clinical information was retrieved from the participants' medical records, CIPN symptoms were collected using the European Organisation for Research and Treatment of Cancer CIPN20 and analysed.</p><p><strong>Results: </strong>Two hundred and sixty-one female breast cancer patients receiving either neoadjuvant or adjuvant chemotherapy were enrolled in the study. The mean age was 49.98 +/- 11.4 years. 72.9% (183) among the study participants reported symptoms of CIPN at the end of chemotherapy. One hundred and fifty-seven (62.5%) had mild neuropathy, 23(9.2%) had moderate neuropathy and 3 (1.2%) had severe neuropathy. 31.1% (74) of patients at 2 months after completion of chemotherapy still reported symptoms of CIPN. Numbness in both hands and legs was found to be the most common symptom reported by the participants and the majority of the participants experienced mild to moderate symptoms.</p><p><strong>Conclusion: </strong>The prevalence of CIPN was high at the completion of chemotherapy (72.9%), and there was a significant decline in the prevalence at two months after completion of treatment (31.1%). Numbness was the most commonly reported symptom among the participants and the majority of the participants experienced mild symptoms of peripheral neuropathy.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1791"},"PeriodicalIF":1.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735128/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of glass slide morphology (GSM) and whole slide image (WSI) in the diagnosis of acute leukemia (AL) by types.","authors":"Hamisa Iddy, Ahlam Nasser, Ally Hussein, Anna Schuh, Clara Chamba","doi":"10.3332/ecancer.2024.1790","DOIUrl":"10.3332/ecancer.2024.1790","url":null,"abstract":"<p><p>Acute leukemia (AL) is a diverse group of hematological malignancies characterised by the accumulation of immature blast cells in the bone marrow. Accurate classification into acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) is essential for treatment and prognosis. This study aimed to assess the performance of glass slide morphology (GSM) using a light microscope versus whole slide imaging (WSI) in diagnosing and classifying AL, using flow cytometry as the gold standard test. Peripheral smears and bone marrow aspirates from 97 patients suspected of AL were stained with Romanowsky stain and reviewed by a single hematologist. For GSM, the hematologist was provided with a single slide, which was to be evaluated under a light microscope. For WSI, the Alexapath mobile scanner (ADA1) was used to scan the slides for review by the hematologist. Patient identification was concealed from the interpreting hematologist, and an interval of 2 weeks was set between the review of GSM and WSI of the same patient. The sensitivity and specificity of GSM and WSI were compared to the results of flow cytometry. Out of the 97 patients suspected to have AL, 47 were confirmed to have AL by flow cytometry. Among these, 19 (40.4%) were diagnosed with AML and 28 (59.6%) with ALL. GSM demonstrated high sensitivity (89.4%) and specificity (90.0%) for diagnosing AL, but lower sensitivity in distinguishing AML (57.9%) from ALL (75.0%). Similarly, WSI exhibited a reasonable sensitivity (80.9%) and high specificity (98.0%) for diagnosing AL, but lower sensitivity in differentiating AML (57.9%) and ALL (46.4%). GSM and WSI are reasonable and acceptable techniques for accurately screening AL cases and accelerating referral to tertiary centers of excellence.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1790"},"PeriodicalIF":1.2,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrathecal pemetrexed in NSCLC patients with leptomeningeal metastasis.","authors":"Vanita Noronha, Vijay Patil, Zoya Peelay, Monica Reddy Yallala, Nandini Menon, Minit Shah, Shatabdi Chakraborty, Kumar Prabhash","doi":"10.3332/ecancer.2024.1792","DOIUrl":"https://doi.org/10.3332/ecancer.2024.1792","url":null,"abstract":"<p><p>Spread of lung cancer to the leptomeninges is rare and difficult to treat. Standard therapy comprises CNS-penetrant targeted agents with or without intrathecal chemotherapy. We performed a retrospective analysis of 16 patients with advanced NSCLC and leptomeningeal disease treated with intrathecal pemetrexed 50 mg. All tumours were adenocarcinoma histology; 13 (81.3%) had EGFR mutations, and 3 (18.8%) had no targetable mutations. Prior therapies included EGFR-directed tyrosine kinase inhibitors (TKI) with/without chemotherapy/antiangiogenic agents (9 [56.3%]), chemotherapy alone (4 [25%]), intrathecal methotrexate with/without hydrocortisone (3 [18.9%]), and radiation (12 [75%]). Presenting symptoms of leptomeningeal disease included headache (10 [62.5%]), dizziness (8 [50%]), and seizures (7 [43.8%]). Systemic therapy administered along with intrathecal pemetrexed included osimertinib (5 [31.3%]), gefitinib in 1 (6.3%), chemotherapy in 4 (25%) (pemetrexed + carboplatin-2, cisplatin + etoposide-1, paclitaxel-1), chemotherapy + oral TKI in 5 (31.3%) and no systemic therapy in 1 (6.3%). Neurological symptoms following intrathecal pemetrexed included headache in 1 (6.3%) patient which was likely due to raised intracranial pressure from underlying leptomeningeal disease, and anxiety/uneasiness in 1 (6.3%). Grade 3 or higher toxicities included thrombocytopenia (6 [37.5%]), anaemia (4 [25%]), neutropenia (4 [25%]), febrile neutropenia (3 [18.8%]), mucositis (4 [25%]), diarrhoea (1 [6.3%]), rash (1 [6.3%]) and hypokalemia (1 [6.3%]. Most toxicities were likely caused by systemic chemotherapy, rather than by intrathecal pemetrexed. Intrathecal pemetrexed was delayed in 9 (56.3%) patients, due to cytopenias/febrile neutropenia (8 [50%]) and poor general condition (1 [6.3%]). Median OS from diagnosis of leptomeningeal disease was 7.5 months (95% CI: 1.2-13.8). Median OS from start of intrathecal pemetrexed was 2.7 months (95% CI, 1.1-4.3). Thus, intrathecal pemetrexed combined with systemic antitumor therapy was tolerable, with promising clinical outcomes in patients with NSCLC and leptomeningeal disease. It is important to explore this option, especially in driver mutation-negative NSCLC patients.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1792"},"PeriodicalIF":1.2,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nodular basal cell carcinoma of the scrotum: a case report and review of the literature.","authors":"Gustavo Hipólito Diaz Infantes, Edgar Fermín Yan Quiroz, Luis Fernando Meza Montoya, José Richard Tenazoa Villalobos","doi":"10.3332/ecancer.2024.1789","DOIUrl":"10.3332/ecancer.2024.1789","url":null,"abstract":"<p><p>Basal cell carcinoma (BCC) is the most common non-melanoma type of skin cancer described in humans that originates in the epidermis, more specifically in the basal layer and its appendages. Environmental, genetic and phenotypic factors contribute to the onset of this cancer; however, damage caused by ultraviolet radiation from sunlight is the primary risk factor. The emergence of this neoplasm in unexposed body areas, such as the soles, groin, armpit, scrotum or vulva is very rare. We present this case of a 71-year-old man with a tumour in the middle raphe of the scrotum histologically confirmed as BCC, which was successfully surgically managed.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1789"},"PeriodicalIF":1.2,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of a communal multidisciplinary tumour board on medical education.","authors":"Oluwaseyi K Idowu, Adewumi O Alabi, Ibijoke A Idowu, Opeyemi I Olusunmade, Bright A Igbinoba, Abdulwahab Ajani, Mohammed Y M Habeebu, Jane U Igwilo, Kolawole O Aramide, Eyitayo O Alabi, Fatimah B Abdulkareem, Samuel U Eyesan, Suleiman O Giwa","doi":"10.3332/ecancer.2024.1788","DOIUrl":"10.3332/ecancer.2024.1788","url":null,"abstract":"<p><strong>Introduction: </strong>Numerous challenges hinder the development of multidisciplinary medical education in a resource-constrained environment. Communal tumour boards built through networking could be a suitable model for the effective management of diseases and enhancement of medical education. This study evaluated the impact of an integrated care pathway for patients with musculoskeletal tumours via multi-institutional networking in a metropolis.</p><p><strong>Methodology: </strong>Musculoskeletal tumours managed in different institutions in a large metropolis were included for discussion at monthly meetings, under the aegis of the Lagos Musculoskeletal Oncology Network (LAMON). The cases discussed were collated and presented by designated senior residents. The meetings ensured adherence to agreed national and international guidelines in the management of musculoskeletal tumours. Decisions about the treatment modalities were planned at the meetings. The impact on medical residency training was evaluated using the achievement of significant milestones by the residents supported by the network.</p><p><strong>Results: </strong>The tumour board network included health professionals from various specialist hospitals in the metropolis. Within the decade (2013-2022), 1,272 patients were reviewed of which 968 patients had definitive histological diagnoses. There was an improvement in limb salvage rate and disease outcome. The tumour board supported significant milestones in graduate medical training, including the completion of 4 residents' fellowship dissertations, 22 conference presentations by residents, the publication of 12 articles by residents and the completion of an orthopaedic oncology subspecialty fellowship by 9 orthopaedic surgeons.</p><p><strong>Conclusion: </strong>The tumour board/network improved the outcome of musculoskeletal tumours over the study period. The network improved the education of medical doctors and increased the capacity for training newer instructors in a resource-limited environment. Perhaps with appropriate social and corporate support, communal tumour boards like LAMON may translate into a good model for multidisciplinary care of diseases and capacity building in resource-limited settings.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1788"},"PeriodicalIF":1.2,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment landscape of patients with HER2+ early breast cancer: an overview.","authors":"Frederic Ivan L Ting","doi":"10.3332/ecancer.2024.1787","DOIUrl":"10.3332/ecancer.2024.1787","url":null,"abstract":"<p><p>Breast cancer is the most common malignancy in terms of incidence and is the leading cause of cancer deaths among women worldwide. In the Philippines, 33,079 new cases of breast cancer were documented in 2020 comprising 17.5% of all new cancer diagnoses. With a rate of 27 deaths per 100,000 people, the Philippines is the frontrunner in Asia for breast cancer mortality. HER2/neu-positive breast cancer, a more aggressive subtype associated with poorer survival outcomes, is present in about 23.5%. Fortunately, the emergence of HER2-targeted therapies has considerably improved disease-free survival and overall survival. This article reviews the most recent data in the HER2+ early breast cancer space.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1787"},"PeriodicalIF":1.2,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health literacy and breast cancer preventive practices among market women in Oshodi Local Government Area of Lagos State, Nigeria.","authors":"Omolara Aminat Fatiregun, Yetunde Kuyinu, Adewunmi Alabi, Anthonia Sowunmi, Okunuga Ndidi, Popoola O Abiodun, Temitope Olatunji-Agunbiade, Oyekan Ademola, Nnodimele Onuigbo Atulomah, Awotayo Olajumoke","doi":"10.3332/ecancer.2024.1785","DOIUrl":"10.3332/ecancer.2024.1785","url":null,"abstract":"<p><strong>Background: </strong>Health literacy connotes understanding health-related issues and applying a clear understanding of implications in making decisions about one's healthcare needs. Early detection and prompt treatment are cornerstone strategies of breast cancer control. This study assessed the relationship between health literacy and breast cancer prevention practices.</p><p><strong>Methods: </strong>This study was conducted in Lagos State. Participants' socio-demographic characteristics, knowledge about breast cancer, attitude towards breast cancer and practice of screening methods available were obtained. Health literacy was assessed with the health literacy domain of a validated questionnaire (Cronbach's alpha of 0.75) validated by test-retest reliability) that evaluated the ability to use a language to understand health instructions, cognitive awareness of basic health-related situations, symptom recognitions and health actions required. Health literacy variables were measured on a 19-point rating scale.</p><p><strong>Results: </strong>Most participants(40%) were between the ages of 31 and 40, while women aged 60 years and above constituted the least proportion (3.1%) of the sample. The mean health literacy score was 12.27 (SD+1.5). A significant proportion(78.4%) of the women had heard of breast cancer. Participants with university/HND education are less likely (OR = 0.431; 95%CI = 0.039,0.759) to have low health literacy. Also, participants with higher income were less likely to have low health literacy, and knowledge of breast cancer risk factors was generally low.</p><p><strong>Conclusion: </strong>This study shows an above-average mean health literacy score amongst these women; however, inadequate knowledge of risk factors still exists. Education level and income are significant in increasing health literacy on breast cancer preventive practices amongst market women in Lagos, Nigeria.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1785"},"PeriodicalIF":1.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735129/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and associated factors of herbal medicine use among breast cancer patients: a cross-sectional study in Morocco.","authors":"Anass Baladi, Mohammed El Fadli, Hassan Abdelilah Tafenzi, Kawtar El Bouaouidi, Nada Benhima, Leila Afani, Ismail Essâdi, Rhizlane Belbaraka","doi":"10.3332/ecancer.2024.1786","DOIUrl":"10.3332/ecancer.2024.1786","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Despite advances in modern medicine, an increasing number of breast cancer (BC) patients are turning to complementary and alternative medicine, such as phytotherapy. Instead of being prescribed by breast medical oncologists, patients are often seeking out phytotherapy themselves. They typically resort to herbal medicine as an alternative treatment to alleviate symptoms and side effects and enhance their quality of life during cancer treatment. This study, conducted in Morocco, aimed to investigate the prevalence and associated factors of herbal medicine use among BC patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A cross-sectional study of 170 patients with BC was carried out from October 2021 to January 2022 at the Mohamed VI University Hospital in Marrakech. Participants were selected using convenience sampling based on specific criteria such as being over 18 years old, having a histological diagnosis of BC, and being in active treatment. Data were collected through a structured questionnaire administered by trained clinicians, and medical records were reviewed for clinical data. Statistical analysis was conducted using Microsoft Forms for data collection and SPSS version 26 for statistical analysis. Descriptive statistics summarised demographic and health-related characteristics. Associations between herbal medicine use and categorical variables were assessed using chi-square and Fisher exact tests. Logistic regression analyses were performed to identify predictors of herbal medicine use, with statistical significance set at &lt;i&gt;p&lt;/i&gt; &lt; 0.05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among the 170 BC patients included in the study, 37% reported using phytotherapeutics. One of the significant findings of this study was that nearly half of the BC patients surveyed believed herbal remedies to be harmless. None of the patients received information about herbal medicine use from their attending physicians. The use of herbal medication was significantly associated with marital status adjusted odds ratio (AOR: NR, &lt;i&gt;p&lt;/i&gt; = 0.019), residence (AOR: 2.291, 95% confidence interval (CI): 1.214-4.324, &lt;i&gt;p&lt;/i&gt; = 0.019), education levels (AOR: NR, &lt;i&gt;p&lt;/i&gt; = 0.04) and receipt of radiotherapy (AOR: 0.128, 95% CI: 0.016-1.007, &lt;i&gt;p&lt;/i&gt; = 0.023). Widowed women had a four times higher probability of using medicinal herbs than single or divorced women (AOR: 4.95, 95% CI: 1.16-20.90, &lt;i&gt;p&lt;/i&gt; = 0.03). Illiterate women (AOR: 0.18, 95% CI: 0.052-0.65, &lt;i&gt;p&lt;/i&gt; = 0.009) or those who attended Koranic school (AOR: 0.04, 95% CI: 0.004-0.47, &lt;i&gt;p&lt;/i&gt; = 0.01) were less likely to use herbal medicine. Urban women were about twice as likely to use herbal remedies as women from rural areas (AOR: 2.02, 95% CI: 1.002-4.09, &lt;i&gt;p&lt;/i&gt; = 0.049).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This study highlights the need for healthcare professionals to be aware of their patients' possible use of herbal medicine, be familiar with commonly used herbal treatments, and take proa","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1786"},"PeriodicalIF":1.2,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nasopharyngeal, tongue and laryngeal cancer in Southern Ethiopia: a seven-year retrospective cross-sectional review.","authors":"Achamyelesh Gebretsadik, Netsanet Bogale, Dereje Geleta, Nebiyu Melaku, Dubale Dulla","doi":"10.3332/ecancer.2024.1784","DOIUrl":"10.3332/ecancer.2024.1784","url":null,"abstract":"<p><strong>Background: </strong>The burden of cancer is increasing globally and is having a negative impact on people's physical, mental and financial health. On the other hand, developing countries are not progressing to prevent the disease at the same rate as the disease burden increases. The development of strategies for cancer prevention, control and treatment that contribute to the community's improved health requires knowledge of cancer epidemiologic data. There is relatively little epidemiologic evidence of nasopharyngeal, tongue and laryngeal cancer in southern Ethiopia. This study aimed to assess the epidemiological burden of nasopharyngeal, tongue and laryngeal cancer among patients treated at Hawassa University Comprehensive and Specialised Hospital (HUCSH) between 2013 and 2019.</p><p><strong>Methods: </strong>A cross-sectional retrospective review was conducted among 3,002 patients who attended the oncologic care at HUCSH. Data were retrieved between February and May 2020. Data were entered using Epi-data version 3.1 and the data were then exported to IBM SPSS version 22 (IBM Corporation, Armonk, NY, USA) for further processing and analysis. A descriptive analysis was done.</p><p><strong>Result: </strong>A total of 280 (9.3%) new head and neck cancer (HNC) patients were identified over a period of 7 years. Nasopharyngeal cancer accounts for more than one-fourth (26.4%) of all HNCs, followed by tongue 15% and laryngeal 14.6% cancers. Males constituted nearly two-thirds of the cases. The overall caseloads doubled over the retrieved years.</p><p><strong>Conclusion: </strong>According to this study, nasopharyngeal, tongue and laryngeal cancer is a more prominent cause of morbidity. According to place, person and time, the frequency of nasopharyngeal, tongue and laryngeal cancer steadily rose in both sexes and across all age categories. Therefore, immediate intervention is needed nationwide to monitor the disease's explosive growth.</p>","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"18 ","pages":"1784"},"PeriodicalIF":1.2,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143002034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}