ecancermedicalscience最新文献

{"title":"Determinants of breast cancer in Ethiopia: a systematic review and meta-analysis","authors":"Lencho Kajela Solbana, Eshetu Ejeta Chaka","doi":"10.3332/ecancer.2023.1624","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1624","url":null,"abstract":"Background: Breast cancer (BC) is the first leading cancer sharing about 25% of the cancer burden among women globally. This study aimed to identify the determinants of BC in Ethiopia. Methods: We comprehensively searched primary studies conducted in Ethiopia on associated factors of BC in PubMed, Cochrane Library, Hinari, Google, and Google Scholar) and available online until 2 June 2023. The necessary data were extracted from relevant studies and exported to STATA version 15 for analysis. The pooled odds ratio with its 95% confidence interval (CI) was estimated using a random effect model. The finding was reported following preferred reporting items for systematic reviews and meta-analyses guidelines. Results: Five studies with 1,819 participants (792 cases and 1,027 controls) were included. The significant determinants of BC were age at menarche <12 years (adjusted odds ratio (AOR) = 3.36, 95% CI: 1.68–5.04), post-menopause (AOR = 2.37, 95% CI: 1.67–3.06), ever breastfeeding (AOR = 0.28, 95% CI: 0.15–0.42), and family history of cancer (AOR = 2.39, 95% CI: 1.29–3.44). Conclusion: In Ethiopia, the significant determinants of BC among women were age at menarche <12 years, post-menopause, Ever breastfeeding, and family history of cancer. We","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"107 31","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135136801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change and oncology nursing: the African perspective","authors":"Vera Larfi Samba, Esubalew Mezgebu, Habtamu Habtes, Naomi Ohene Oti, Bilonda Michou Mangongolo, Ritah Bafumba, Kathryn Burns, Maria Fernanda Olarte Sierra, Julia Challinor, Martjie de Villiers","doi":"10.3332/ecancer.2023.1621","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1621","url":null,"abstract":"Climate change is impacting the lives of millions around the world and exacerbating existing challenges in healthcare globally. Although Africa contributes only 2%–3% of global greenhouse gas emissions, it suffers a disproportionate share of the environmental impact. High-income countries dominate the global discourse on climate change, while their continued utilisation of extractive policies exacerbates climate hazards and impacts economies in regions not responsible for the damage. Cancer is on the rise and constitutes a significant public health burden in low-and middle-income countries, yet little is known about the impact of climate change on oncology nursing on the African continent. To address the ways that climate change is exacerbating existing challenges and adding new difficulties for oncology care, it is essential that the expertise of professionals working in settings that are most impacted by the threats of climate change is amplified if climate crisis risks are to be effectively mitigated. Seven African oncology nurses from across sub-Saharan Africa were reflexively interviewed by voice over internet protocol (VOIP) in English to learn about their understanding of climate change and experiences with its impact on nursing care. Using a conceptual framework to map the impact of climate change on health and considering the vulnerability and social capacity of patients with cancer, our findings show how existing challenges to oncology nursing care are exacerbated by climate change on the continent. Food insecurity, national economic dependency on the agricultural sector, economic inequality, social vulnerability and isolation, transportation challenges, and the immuno-compromised status of patients with cancer are all key concerns for oncology nurses in this context. We also present the nurses’ specific recommendations for governments, hospital authorities, and oncology nurses regarding climate change mitigation, adaptation, and event response strategies. With this work, we aim to lay a foundation for further investigation and action to mitigate the oncoming challenges of climate disaster for oncology nurses across sub-Saharan Africa and the patients and families they care for.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cancer care in Lebanon and the climate-proofing of a burning phoenix","authors":"Mohamad Ibrahim","doi":"10.3332/ecancer.2023.ed130","DOIUrl":"https://doi.org/10.3332/ecancer.2023.ed130","url":null,"abstract":",","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change in Türkiye and its impact on oncology nurses","authors":"Afsin Ahmet Kaya, Aydanur Aydin, Gülcan Bağçivan","doi":"10.3332/ecancer.2023.1623","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1623","url":null,"abstract":"Climate change threatens human life and health by negatively affecting the basic components of health such as clean air, safe drinking water, nutritious food supply, and safe shelter. Türkiye is a country that is largely exposed to climate change with its cosmopolitan location, which is a bridge between Asia and Europe. Due to climate change, serious effects are seen in all sectors from energy to agriculture, from the economy to health. Climate change is defined as the most important global health threat of the next century, and the problems it brings are seen as the most important pressure factor for the life opportunities of future generations. Food and fresh water availability, rising sea levels, abnormal weather events, migration, and diseases are thought to affect human health. A multidisciplinary approach is required to adapt to climate change’s health effects and reduce its negative health effects. In addition, it is predicted that diseases that are about to disappear will re-emerge and become threats. It is thought that as a result of the contamination of food and water resources with the changing ecosystem, some infections will increase and society will face them. Nurses are both affected by climate change and its effects on public health. Nurses who remain in this situation have a great role in providing effective awareness for raising public awareness. In recent years, oncology clinics have not been affected by fire, earthquakes, and pandemics in our country. In this respect, it can be stated that the health service in Turkish oncology clinics is carried out uninterrupt-edly and by experts in the field. We learned during the pandemic that the whole world is unprepared for the future effects of climate change. In this direction, nurses should think about solutions for the problems related to climate change in the future.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135285599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Filipino nurses’ experiences and perceptions of the impact of climate change on healthcare delivery and cancer care in the Philippines: a qualitative exploratory survey","authors":"Mary Anne Tanay, Josie Quiambao-Udan, Oliver Soriano, Genevieve Aquino, Paula Melizza Valera","doi":"10.3332/ecancer.2023.1622","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1622","url":null,"abstract":"Background: Because of its geographical location, the Philippines is vulnerable to the effects of climate change and almost all types of natural hazards such as typhoons, earth-quakes, and volcanic eruptions. Cancer is one of the leading causes of death in the Philip-pines and is one of the major public health concerns. Little is known about how climate change affects cancer services in the Philippines. As the biggest workforce in most institutions, having awareness and knowledge about disaster preparedness and management among nurses can help in reducing the devastating effects of natural disasters on health services. Thus, it is important to understand Filipino nurses’ experiences and perception of the impact of climate change on healthcare delivery and cancer care in the Philippines. Aim: This study explored Filipino nurses’ experiences and perception of the impact of climate change on healthcare delivery and cancer care in the Philippines. Methods: This is a descriptive qualitative exploratory study. Participants were recruited using the snowballing technique and completed an online survey. Forty-six nurses who were working in Luzon, Philippines at the time of the data collection were included in the analysis. Data were analysed using thematic analysis. Findings: Three themes were identified, namely: (1) effects of climate change causing disruption and delay in provision of patient care, (2) impact of climate change on nurses and a deep sense of duty, and (3) perceived impact on patients with cancer. Conclusion: Our study findings contribute to the existing literature that focuses on the impact of climate change-related events such as typhoons and floods on healthcare services and nursing staff. Several areas of cancer care are also impacted, particularly delays in treatment such as chemotherapy. Despite the challenges, the nurses in our study demonstrated a deep sense of commitment in carrying out their roles.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of climate change on cancer nursing in Palestine","authors":"Jehad Hawaamdah, Matthew Fowler","doi":"10.3332/ecancer.2023.ed129","DOIUrl":"https://doi.org/10.3332/ecancer.2023.ed129","url":null,"abstract":",","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135241399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change and cancer: an oncology nurse perspective in two Colombian regions","authors":"Natalia Martínez Arias, Ángel Alfonso Aguirre Durán, Mayra Yiseth Ramírez Lozano, Celia Díez de los Ríos de la Serna, María Fernanda Olarte-Sierra, Julia Challinor, Yuli Vanessa Girón Arbelaez, Magali Yolima Mera Díaz, Luz Damaris Rojas Rodríguez","doi":"10.3332/ecancer.2023.1620","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1620","url":null,"abstract":"Given the lack of publications and public policies addressing the relationship between climate change and cancer care in Colombia, we present an exploration of the perspectives and communication practices of a group of nurses from Valle del Cauca and Antioquia. We provide a context based on the available literature on climate change and general health then provide an overview of cancer in the country. Next, we present how oncology nurses have incorporated information about strategies their patients can use to mitigate the effects of climate change on their health. We highlight the centrality of patient-centered communication using a framework from the US National Cancer Institute) and the fundamental role nurses have in patients' experiences throughout their treatment. We conclude with the need to investigate oncology nurse communication practices in other Colombian hospitals, with consideration of culture, cancer stigma, barriers to care and other factors that may influence successful climate change mitigation and to better understand how other Latin American oncology nurses are addressing this serious challenge.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":" 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135242493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging features of breast cancer subtypes on contrast enhanced ultrasound: a feasibility study","authors":"Stuti Chandola, Ekta Dhamija, Shashi B Paul, Smriti Hari, Atul Batra, Sandeep Mathur, SVS Deo","doi":"10.3332/ecancer.2023.1619","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1619","url":null,"abstract":"The objective of this research was to study the contrast enhancement patterns of the different molecular subtypes of breast cancer on contrast-enhanced ultrasound (CEUS) using both qualitative and quantitative parameters. This prospective study included females with a single breast mass which was histopathologically proven carcinoma. B mode ultrasound (USG) and CEUS were performed in all patients during baseline assessment. Qualitative CEUS assessment encompassed enhancement pattern, presence of fill-in and washout. Quantitative assessment included measurement of peak enhancement, time to peak; area under the curve and mean transit time. A p-value < 0.05 was considered statistically significant for differentiating the subtypes. The included thirty masses were categorised into two subtypes—triple negative breast cancer (TNBC) (36.7%) and non-TNBC (63.3%) subtypes. With B-mode USG, a statistically significant difference was observed between the two groups with respect to their shape and margins. TNBC lesions showed an oval shape, circumscribed margins and peripheral nodular enhancement on CEUS with the absence of fill-in even in the delayed phase ( p-value – 0.04). The two subtypes did not significantly differ in terms of quantitative perfusion parameters. The various subtypes of breast cancer therefore possess distinct contrast enhancement patterns. CEUS potentially allows differentiation amongst these molecular subtypes that may aid in radiology-pathology (rad-path) correlation and follow up of the patients.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"15 18","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135973449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gynaecologic oncology surgical cancellations in Zambia","authors":"Samson Chisele, Milindi Mwanahamuntu, Paul Kamfwa, Mukatimui Kalima-Munalula, Swali Fundafunda, Kenneth Chanda, Maya M Hicks, Leeya F Pinder, Krista S Pfaendler, Groesbeck P Parham, Michael L Hicks","doi":"10.3332/ecancer.2023.1617","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1617","url":null,"abstract":"Introduction: Cancellations of elective surgery in low-and middle-income countries (LMIC) are common and a major hindrance for patients who are in need of surgical therapeutic modalities. This is especially important in the context of scaling up needed surgical interventions for gynaecological cancer care. There is a knowledge gap in the literature related to cancellation of gynaecologic oncology surgeries in LMIC, where there is enormous need for this specific cancer surgical capacity. We report in an observational descriptive fashion, our experience at the UTH/CDH in Lusaka, Zambia, on the causes of surgical cancellations in gynaecologic oncology. Methods: From January 1, 2021 through June 31, 2023, we retrospectively evaluated the surgical registry for gynaecologic oncology at the UTH/CDH in Lusaka, Zambia to assess the number and causes of surgical cancellations. Results: There were a total of 66 (16.96%) surgical cancellations out of 389 scheduled gynaecologic oncology cases. Lack of available blood and/or low haemoglobin was the most frequent cause of surgical cancellations, 27 cases (40.90%). Conclusion: We highlight in our series that the lack of blood, leading to surgical cancel-lations was the most frequent impediment related to performing scheduled gynaeco-logic oncology surgical procedures. As gynaecologic oncology services scale up in LMIC, given the radical nature of surgery and its association with blood loss, it is incumbent on the entire clinical ecosystem to address this issue and to develop mitigating strategies, specific to their respective resource setting.","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"19 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135972682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The occurrence and risk factors of chemotherapy-induced neutropenia in patients with breast cancer not receiving primary G-CSF prophylaxis","authors":"Susanna Hilda Hutajulu, Siswi Oktariani, Agus Jati Sunggoro, Bagas Suryo Bintoro, Yufi Kartika Astari, Juan Adrian Wiranata, Irianiwati Widodo, Anita Ekowati, Mardiah Suci Hardianti, Kartika Widayati Taroeno-Hariadi, Johan Kurnianda, Ibnu Purwanto","doi":"10.3332/ecancer.2023.1618","DOIUrl":"https://doi.org/10.3332/ecancer.2023.1618","url":null,"abstract":"Background: Chemotherapy-induced neutropenia (CIN) is a substantial side effect in chemotherapy of breast cancer patients. Administration of granulocyte colony stimulating factor (G-CSF) that may reduce CIN occurrence is not commonly available to many local cases. Objectives: To investigate the occurrence of grade 4 CIN and the influencing factors in breast cancer patients not receiving G-CSF prophylaxis. Methods: One-hundred and eighty-six newly diagnosed breast cancer patients who received a 3-weekly (neo)adjuvant or palliative chemotherapy without primary G-CSF prophylaxis were included. Grade 4 CIN was defined as absolute neutrophil count (ANC) <0.5 × 10 3 /mm 3 during any chemotherapy cycle. We used logistic regression to explore the association of clinical, pathological and treatment factors with the risk of grade 4 CIN in the first cycle and in any given cycle. Results: Fifty-seven (30.6%) patients experienced grade 4 CIN in the first cycle and 145 (78%) had it at least once during chemotherapy. In the first cycle, haemoglobin, ANC, and albumin levels were associated with grade 4 CIN (OR = 1.48, p = 0.031; OR = 0.68, p = 0.006; and OR = 2.07, p = 0.042). In any cycle, pre-treatment ANC levels and anthra-cycline-taxane combination regimen were associated with grade 4 CIN (OR = 0.78, p = 0.032 and OR = 3.64, p = 0.012).","PeriodicalId":11460,"journal":{"name":"ecancermedicalscience","volume":"11 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135973020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}