ECSOC-25最新文献

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Reaction of Some Substituted (Un)Substituted Isatins with 1,ω-Alkanes and Their Products with Sodium Azide 一些1 ω-烷烃取代(Un)取代异黄酮及其产物与叠氮化钠的反应
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11716
Nguyen Minh Tri, V. N. Toan, H. M. Linh, Ngô Thị Thanh Mai, Tran Thi-Hai-Yen, Ngo Thi Thuy, Nguyen Thi Thu Huong, Pham Thi Thuy Van, T. P. H. Yen, Nguyen Thi Quynh Giang, H. T. Van, N. Thanh
{"title":"Reaction of Some Substituted (Un)Substituted Isatins with 1,ω-Alkanes and Their Products with Sodium Azide","authors":"Nguyen Minh Tri, V. N. Toan, H. M. Linh, Ngô Thị Thanh Mai, Tran Thi-Hai-Yen, Ngo Thi Thuy, Nguyen Thi Thu Huong, Pham Thi Thuy Van, T. P. H. Yen, Nguyen Thi Quynh Giang, H. T. Van, N. Thanh","doi":"10.3390/ecsoc-25-11716","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11716","url":null,"abstract":": Azide derivatives of isatins were the initial materials needed for click chemistry, so as to form 1,2,3-triazoles in order to synthesize the hybrid compounds of 1,2,3-triazole–isatin with monosaccharide moieties. The required substituted isatins were prepared according to the Sandmeyer method from corresponding substituted anilines. N -( ω -bromoalkyl) isatins were prepared through the nucleophilic reaction, S N 2, of (un)substituted isatins with appropriate dibromoalkanes. Some ω -azidoalkylisatins were synthesized by the reaction of corresponding ω -bromoalkylisatins with sodium azide. The reactions were performed in dry DMF as solvents in the presence of K 2 CO 3 as the base and KI as the promoting agent. The product yields reached 30–85%.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87368892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Weak Donor, Strong Acceptor Thienopyrazine-Based Polymers for Fine Tuning of LUMO Levels—Suitable Materials for Energy and Storage Solutions 弱施主,强受体噻吩吡嗪基聚合物用于LUMO能级微调-适合于能源和存储解决方案的材料
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11742
B. Squeo, Elisa Lassi, C. Botta, S. Luzzati, B. Vercelli, S. Zappia, M. Pasini
{"title":"Weak Donor, Strong Acceptor Thienopyrazine-Based Polymers for Fine Tuning of LUMO Levels—Suitable Materials for Energy and Storage Solutions","authors":"B. Squeo, Elisa Lassi, C. Botta, S. Luzzati, B. Vercelli, S. Zappia, M. Pasini","doi":"10.3390/ecsoc-25-11742","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11742","url":null,"abstract":"A single paragraph of about 100 words to give a brief introduction to your work.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86993960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reaction of N-(tosylmethyl)ureas with NaCN: Synthetic and Mechanistic Aspects N-(甲基)脲与NaCN的反应:合成及机理研究
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11759
A. Fesenko, A. Shutalev
{"title":"Reaction of N-(tosylmethyl)ureas with NaCN: Synthetic and Mechanistic Aspects","authors":"A. Fesenko, A. Shutalev","doi":"10.3390/ecsoc-25-11759","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11759","url":null,"abstract":": Reaction of NaCN with N -(tosylmethyl)ureas, prepared by condensation of urea with aldehydes and p -toluenesulfinic acid, has been studied. Generally, this reaction afforded the corresponding α -ureido nitriles. Some mechanistic aspects of cyanide-anion amidoalkylation with N -(to-sylmethyl)ureas were discussed based on DFT calculations.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76657907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis, Insecticidal Activity and Nanoencapsulation Studies of Alkoxy Alcohols from Eugenol 丁香酚烷氧醇的合成、杀虫活性及纳米包封研究
ECSOC-25 Pub Date : 2021-11-14 DOI: 10.3390/ecsoc-25-11788
Catarina M. M. Coelho, M. J. Fernandes, David M. Pereira, R. Pereira, A. Fortes, M. S. T. Gonçalves, E. M. Castanheira
{"title":"Synthesis, Insecticidal Activity and Nanoencapsulation Studies of Alkoxy Alcohols from Eugenol","authors":"Catarina M. M. Coelho, M. J. Fernandes, David M. Pereira, R. Pereira, A. Fortes, M. S. T. Gonçalves, E. M. Castanheira","doi":"10.3390/ecsoc-25-11788","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11788","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82974901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Green Synthesis of Fluorescent Carbon Dots through Solvothermal Treatment of Buchnania lanzan Leaf Extract 溶剂热处理蓝菖蒲叶提取物绿色合成荧光碳点
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11648
P. Jana, A. Dev
{"title":"Green Synthesis of Fluorescent Carbon Dots through Solvothermal Treatment of Buchnania lanzan Leaf Extract","authors":"P. Jana, A. Dev","doi":"10.3390/ecsoc-25-11648","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11648","url":null,"abstract":": In the present work we have synthesized fluorescent carbon dots (CDs) through solvothermal treatment of Buchnania lanzan leaves extract at 160 °C for 4 h in oven. Here, Buchnania lanzan leaves serve as a renewable source of carbon. The obtained blackish brown CDs solution was centrifuged and the supernatant was filtered through syringe filter (0.22 µm). Further, the CDs solution was dried in vacuum oven to obtain powder. The synthesized CDs were characterized by different techniques including UV-Visible spectroscopy, fluorescence spectroscopy, fourier trans-form infrared (FTIR), zeta potential, x-ray diffraction (XRD). The as prepared CDs solution was found brownish colored in day light while exhibited green fluorescence under UV light. UV-Visible absorption spectrum displayed characteristic shoulder peaks of CDs at 257 nm and at 356 nm. In the fluorescence spectra, excitation dependent emission behaviour of CDs was seen, which is one of the distinct characteristics of CDs. The negative zeta potential and characteristic peaksin FTIR, suggested presence of carbonyl, amine and hydroxyl functional groups on the CDs surface. XRD spectrum exhibited broad peak at 2θ=19°, suggesting amorphous nature of CDs similar as reported in earlier works. As we have synthesized surface functionalized fluorescent carbon dots from a renewable and abundant precursor, this method can be highly useful in large scale synthesis of carbon dots with reduced costs and will find potential applications in the field of drug delivery,","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80092845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Development and Evaluation of Eberconazole-Loaded Niosomes 埃伯康唑负载Niosomes的开发与评价
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11664
Priyadarshi Aparajay, A. Dev
{"title":"Development and Evaluation of Eberconazole-Loaded Niosomes","authors":"Priyadarshi Aparajay, A. Dev","doi":"10.3390/ecsoc-25-11664","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11664","url":null,"abstract":": Invasive fungal infections require a long treatment schedule; however, treatment has become more cumbersome due to the development of resistance. Most antifungal moieties show systemic toxicity upon oral administration, leading to delivery of antifungal moieties via a topical route. Eberconazole (EBZ) is a BCS class II drug that has poor solubility and high permeability. It is a broad-spectrum imidazole derivative, which acts as a both fungicidal and fungistatic drug by inhibiting ergosterol synthesis. Various topical creams of EBZ are available in the market, but the lack of a proper dosing schedule and rapid removal lead to poor bioavailability. Niosomes are vesicular carriers that can entrap both hydrophilic and lipophilic drugs. Niosomal formulations have been prepared using Span20 (nonionic surfactant) and cholesterol by thin-film hydration (TFH) technique. During preformulation studies, the purity of EBZ was ascertained using FT-IR and melting point studies, while the standard calibration curve was prepared using UV-visible spectroscopy. The prepared niosomal formulations were characterized for their morphology, entrapment efficiency, particle size, and zeta potential. The formulation has shown 86 ± 0.85% entrapment efficiency, while the noisome appeared in a ring-like structure during its microscopic evaluation. Further evaluations of in vitro and in vivo release studies will be performed in the future for its efficacy and antifungal activity.","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87873277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Amide-Stabilized Enols in the Enol-Ugi Reaction: A Five-Component Synthesis of Triamides 烯醇- ugi反应中的酰胺稳定烯醇:五组分合成三酰胺
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11665
A. Neo, M. Castellano, J. L. Ramiro, C. Marcos
{"title":"Amide-Stabilized Enols in the Enol-Ugi Reaction: A Five-Component Synthesis of Triamides","authors":"A. Neo, M. Castellano, J. L. Ramiro, C. Marcos","doi":"10.3390/ecsoc-25-11665","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11665","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78124630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity 富勒烯-1,2,3-三唑:合成及其细胞毒活性
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11659
Z. Sadretdinova, A. Akhmetov, L. Dzhemileva, V. D’yakonov, A. Tuktarov, U. Dzhemilev
{"title":"Fullerenyl-1,2,3-Triazoles: Synthesis and Cytotoxic Activity","authors":"Z. Sadretdinova, A. Akhmetov, L. Dzhemileva, V. D’yakonov, A. Tuktarov, U. Dzhemilev","doi":"10.3390/ecsoc-25-11659","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11659","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75038447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Palladacycles as Functionalized Metal-Ligand Precursors, Contain Tridentate [Csp2, N, S] Ligands 含三齿[Csp2, N, S]配体的功能化金属前体钯环
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11663
Basma Al Janabi, J. M. Vila, J. M. Ortigueira
{"title":"Palladacycles as Functionalized Metal-Ligand Precursors, Contain Tridentate [Csp2, N, S] Ligands","authors":"Basma Al Janabi, J. M. Vila, J. M. Ortigueira","doi":"10.3390/ecsoc-25-11663","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11663","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89000220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the Effect of Selected Piperazine-2,5-Diones on Cartilage-Related Cells 哌嗪-2,5-二酮对软骨相关细胞影响的研究
ECSOC-25 Pub Date : 2021-11-13 DOI: 10.3390/ecsoc-25-11650
J. Jampílek, J. Hošek, P. Bobál
{"title":"Investigation of the Effect of Selected Piperazine-2,5-Diones on Cartilage-Related Cells","authors":"J. Jampílek, J. Hošek, P. Bobál","doi":"10.3390/ecsoc-25-11650","DOIUrl":"https://doi.org/10.3390/ecsoc-25-11650","url":null,"abstract":"","PeriodicalId":11441,"journal":{"name":"ECSOC-25","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86126496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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