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Edible mushrooms: A sustainable novel ingredient for meat analogs 食用菌:肉类类似物的可持续新型配料
eFood Pub Date : 2023-12-10 DOI: 10.1002/efd2.122
Umesh Singh, Pooja Tiwari, Sneha Kelkar, Dikshita Kaul, Abhay Tiwari, Mandira Kapri, Satyawati Sharma
{"title":"Edible mushrooms: A sustainable novel ingredient for meat analogs","authors":"Umesh Singh,&nbsp;Pooja Tiwari,&nbsp;Sneha Kelkar,&nbsp;Dikshita Kaul,&nbsp;Abhay Tiwari,&nbsp;Mandira Kapri,&nbsp;Satyawati Sharma","doi":"10.1002/efd2.122","DOIUrl":"https://doi.org/10.1002/efd2.122","url":null,"abstract":"<p>Meat products are ubiquitously consumed for their higher protein content and characteristic organoleptic properties. The enhanced capacities of meat production to meet the demands of the rapidly increasing global population is causing serious issues relating to health, environment, and animal welfare. Suitable meat alternatives that are protein-rich, sustainable, and healthier are being continuously explored by scientists globally. In this direction, edible medicinal mushrooms can be used as promising healthier meat alternatives as they provide natural meaty texture, flavors and are also rich in proteins, essential amino acids, β-glucans, vitamins, minerals, polyphenols, and antioxidants. Mushrooms have proven medicinal benefits including anticancer, immunomodulatory, antiviral, antihypertensive, antidiabetic, and anti-inflammatory properties. The aim of the present review is to highlight the potential of edible mushrooms to produce meat analogs, various meat and nonmeat-based studies focussing on mushrooms as key meat analog ingredients, impact on the product quality, associated nutraceutical aspects, consumer behavior and market availability of mushroom-based meat analogs.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138564795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A guideline of antiphotoaging activity of polysaccharide assay in vitro and in vivo 多糖体外和体内抗光老化活性测定指南
eFood Pub Date : 2023-11-28 DOI: 10.1002/efd2.121
Hua-Mai Qiu, Lijun You
{"title":"A guideline of antiphotoaging activity of polysaccharide assay in vitro and in vivo","authors":"Hua-Mai Qiu,&nbsp;Lijun You","doi":"10.1002/efd2.121","DOIUrl":"https://doi.org/10.1002/efd2.121","url":null,"abstract":"<p>People have become increasingly concerned about skin beauty and health issues, especially skin photoaging. Previous studies showed that skin photoaging was characterized by skin roughness and dryness. It was caused by UV radiation-related dysregulation of matrix metalloproteinases (MMPs) and oxidative stress. Therefore, to investigate the antiphotoaging activity of polysaccharides, it is critical to establish the skin photoaging model, including the in vitro cellular model and the in vivo animal model. The in vitro cellular model is judged by cell viability, the MMPs expression, oxidative detection, and the quantities of inflammation cytokines. Moreover, both the damage to the epidermis and dermis of nude mice and the change of collagen content in the skin are indicators of the in vivo animal model. Thus, in this guideline, we tried to summarize the practice of antiphotoaging activity for polysaccharides.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138449225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probiotic or probiotics add supplement interferes with coronary heart disease: A meta-analysis of randomized controlled trials 益生菌或添加益生菌补充剂干扰冠心病:随机对照试验的荟萃分析
eFood Pub Date : 2023-11-27 DOI: 10.1002/efd2.120
Lingshuang Yang, Jumei Zhang, Juan Wang, Hui Zhao, Xinqiang Xie, Qingping Wu
{"title":"Probiotic or probiotics add supplement interferes with coronary heart disease: A meta-analysis of randomized controlled trials","authors":"Lingshuang Yang,&nbsp;Jumei Zhang,&nbsp;Juan Wang,&nbsp;Hui Zhao,&nbsp;Xinqiang Xie,&nbsp;Qingping Wu","doi":"10.1002/efd2.120","DOIUrl":"https://doi.org/10.1002/efd2.120","url":null,"abstract":"<p>The effect of probiotics or probiotics add supplement on improving clinical outcomes of coronary heart disease (CHD) has produced conflicting results. This meta-analysis aimed to evaluate the effect of probiotics supplementation or probiotics add supplement on blood glucose, lipids, blood pressure, inflammatory reaction, oxidative stress, and depress score in patients with CHD. Search PubMed, Web of Science, Embase, and Cochrane Library databases for relevant studies from February 1974 to September 2022. Pooled results were calculated using a fixed-effect model to assess the effects of probiotics supplementation or probiotics add supplement in CHD. A total of 10 randomized controlled trials were included in this analysis. Overall, probiotics add supplement showed statistically significant reductions in triglycerides, insulin, homeostasis model of assessment-insulin resistance (HOMA-IR), high-sensitivity C-reactive protein (hs-CRP), interleukin-6, and Beck Depression Inventory (BDI) score, compared to the control group (standardized mean difference [SMD]: −0.35 mg/dL; SMD: −0.64 μIU/mL; SMD: −0.90; SMD: −0.57 mg/dL; SMD: −0.60 pg/mL; SMD: −0.52; respectively), but high-density lipoprotein cholesterol, nitric oxide (NO) were statistically significant increased (SMD: 0.45 mg/dL; SMD: 1.01 μmol/L; respectively). Then, probiotics showed statistically significant reductions in hs-CRP, and Beck Anxiety Inventory score BDI (SMD: −0.50 mg/dL; SMD: −0.67; SMD: −0.41; respectively). Moreover, subgroup analyses revealed that low-density lipoprotein cholesterol, HOMA-IR, diastolic blood pressure, NO indicators may influence by patients age, body mass index (BMI), duration of the supplement and dose of probiotics. Our analysis showed that probiotics supplementation or probiotics add supplement improved glucolipid metabolism, inflammatory response, oxidative stress, and depressive disorder, particularly the patients who ages ≥60, baseline BMI &lt;30 kg/m<sup>2</sup>, duration of intervention more than 12 weeks and the dose of probiotics ≥8 × 10<sup>9</sup> CFU/day. The PROSPERO ID was CRD42022357385.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138449530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10-induced pulmonary inflammation by promoting PINK1/Parkin signaling pathway-mediated alveolar macrophage mitophagy 黑果野莓花青素-3-半乳糖苷通过促进PINK1/Parkin信号通路介导的肺泡巨噬细胞自噬来改善pm10诱导的肺部炎症
eFood Pub Date : 2023-11-06 DOI: 10.1002/efd2.119
Xia Liu, Xiaowei Zhang, Yan Gao, Jinlong Tian, Jin Zhao
{"title":"Cyanidin-3-galactoside from Aronia melanocarpa ameliorates PM10-induced pulmonary inflammation by promoting PINK1/Parkin signaling pathway-mediated alveolar macrophage mitophagy","authors":"Xia Liu,&nbsp;Xiaowei Zhang,&nbsp;Yan Gao,&nbsp;Jinlong Tian,&nbsp;Jin Zhao","doi":"10.1002/efd2.119","DOIUrl":"10.1002/efd2.119","url":null,"abstract":"<p><i>Aronia melanocarpa</i> is rich in anthocyanin, among which cyanidin-3-galactoside (C3G) is the most abundant. Here, we established an experimental model of mice and alveolar macrophage cell line MH-S exposed to PM10, and C3G was administered to explore the underlying mechanism of C3G exerting protective effects on PM10-induced lung inflammation. The results showed C3G alleviated PM10-induced lung inflammation by reducing matrix metalloproteinases production at both gene and protein levels as well as pro-inflammatory cytokine levels. Autophagy was activated in PM10-injured alveolar macrophages (AMs), and C3G promoted autophagy indicated by LC3, BECN1, Atg5, Bcl-2, and P62 expression, and C3G further resisted PM10-induced AMs apoptosis. Besides, C3G could promote Pink1/Parkin-mediated mitochondrial autophagy of AMs to alleviate the overexpression of mitochondrial reactive oxygen species (ROS) so that maintain mitochondrial membrane potential and ATP productions to restrict the distribution of Cyt-c and further reduce the increasing of caspase 3/7 activity. Therefore, C3G enhanced the clearance of PM10-damaged mitochondria by promoting AMs mitophagy, thereby reducing the activation of mitochondria-dependent apoptosis pathway and the production of excess ROS, which reduced AMs apoptosis and secretion of pro-inflammatory factors to ameliorate PM10-induced pulmonary inflammation, suggesting that C3G may be as a functional food ingredient with the potential to improve lung health.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135684696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zhenjiang aromatic vinegar prevents the alcohol liver disease in mice via autophagy 镇江香醋通过自噬预防小鼠酒精性肝病
eFood Pub Date : 2023-10-25 DOI: 10.1002/efd2.118
Yuxuan Zhao, Ting Xia, Xiao Qiang, Yongqi Wang, Chaoyan Kang, Yuan Meng, Yan Cheng, Min Wang, Jianbo Xiao
{"title":"Zhenjiang aromatic vinegar prevents the alcohol liver disease in mice via autophagy","authors":"Yuxuan Zhao,&nbsp;Ting Xia,&nbsp;Xiao Qiang,&nbsp;Yongqi Wang,&nbsp;Chaoyan Kang,&nbsp;Yuan Meng,&nbsp;Yan Cheng,&nbsp;Min Wang,&nbsp;Jianbo Xiao","doi":"10.1002/efd2.118","DOIUrl":"10.1002/efd2.118","url":null,"abstract":"<p>Alcoholic liver disease (ALD) is an ignored global issue of public health. It is urgent for searching bioactive foods to prevent ALD. Zhenjiang aromatic vinegar (ZAV) contained antioxidant compounds, including polyphenols, flavonoids, and melanoidins. The mechanism of ZAV on preventing acute liver injury was evaluated in alcohol-treated mice. Our results showed that ZAV ameliorated morphological damage by hematoxylin and eosin and Oil Red O staining in alcohol-treated liver. ZAV relieved symptoms of ALD, which presented as decreased serum triacylglycerol, total cholesterol, alanine transaminase, and aspartate aminotransferase levels. In addition, ZAV treatment inhibited hepatic oxidative stress levels by downregulating reactive oxygen species generation, and the oxidative products (malonaldehyde, 4-hydroxynonenal, and 8-hydroxydeoxyguanosine), and upregulating catalase, superoxide dismutase, glutathione, and glutathione peroxidase. ZAV further reduced production of tumor necrosis factor-α and monocyte chemoattractant protein-1, and elevated levels of interleukin-4 and transforming growth factor-β indicating the inhibition of alcohol-induced inflammation. Furthermore, ZAV treatment increased expression levels of autophagy-associated proteins in ALD mice by western blot, which participated in anti-ALD effect of ZAV. These findings demonstrate that ZAV could be an alternative for ALD intervention by regulating oxidative stress and autophagy.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135169427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of extraction methods, proximate composition, and physicochemical and functional properties of fruit seed proteins: A comprehensive review 水果种子蛋白的提取方法、基本成分、理化性质和功能特性的比较分析
eFood Pub Date : 2023-10-24 DOI: 10.1002/efd2.117
Adharsh Ashok N., Manmath Sontakke
{"title":"Comparative analysis of extraction methods, proximate composition, and physicochemical and functional properties of fruit seed proteins: A comprehensive review","authors":"Adharsh Ashok N.,&nbsp;Manmath Sontakke","doi":"10.1002/efd2.117","DOIUrl":"10.1002/efd2.117","url":null,"abstract":"<p>This comprehensive review delves into the realm of fruit seed proteins, examining their extraction methods, physicochemical properties, and functional characteristics. These proteins exhibit tremendous potential for diverse applications within the food industry. By gaining insights into efficient extraction techniques and understanding the physicochemical and functional properties of fruit seed proteins, researchers and industry professionals can harness their advantages to develop innovative food products. Various extraction methods, such as acid alkali, microwave-assisted, ultrasound-assisted, reverse micelle extraction, and the Box–Behnken experimental design, have been used for extracting proteins from a range of fruit seeds, including jackfruit, kiwi, watermelon, date palm, and grape seeds. The selection of these methods was based on their efficiency, protein yield, and compatibility with fruit seed proteins, with any associated limitations duly acknowledged by the researchers. The review also explores physicochemical characterization techniques such as Fourier transform infrared, thermogravimetric analysis, differential scanning calorimetry, and scanning electron microscopy, used specifically for jackfruit seed protein, while delving into essential functional properties including solubility, water-binding capacity, oil-binding capacity, emulsifying capacity, foaming capacity, and bulk density. These properties play a crucial role in determining the suitability of fruit seed proteins for various food applications, significantly impacting factors like texture, crispiness, and color. Waste fruit seeds, often overlooked, can serve as a valuable source of proteins, possessing multifunctional properties encompassing nutrition, structure, enzymes, emulsification, foaming, gelation, and thickening. However, compared to other protein sources, fruit seed proteins have received limited scientific attention, rendering this review a distinctive and valuable contribution to the existing literature by offering comprehensive insights into extraction methods and properties.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135267022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pomegranate peel polyphenols as an antioxidant additive for the development and characterization of a new active pectin edible film 石榴皮多酚抗氧化添加剂用于新型活性果胶食用膜的研制与表征
eFood Pub Date : 2023-10-19 DOI: 10.1002/efd2.115
Rene Diaz-Herrera, Olga B. Alvarez-Pérez, Janeth Ventura-Sobrevilla, Alberto Ascacio-Valdés, Miguel A. Aguilar-Gonzalez, Juan Buenrostro-Figueroa, Cristobal N. Aguilar
{"title":"Pomegranate peel polyphenols as an antioxidant additive for the development and characterization of a new active pectin edible film","authors":"Rene Diaz-Herrera,&nbsp;Olga B. Alvarez-Pérez,&nbsp;Janeth Ventura-Sobrevilla,&nbsp;Alberto Ascacio-Valdés,&nbsp;Miguel A. Aguilar-Gonzalez,&nbsp;Juan Buenrostro-Figueroa,&nbsp;Cristobal N. Aguilar","doi":"10.1002/efd2.115","DOIUrl":"https://doi.org/10.1002/efd2.115","url":null,"abstract":"<p>Natural origin products are an appealing substitute for nonbiodegradable materials in the production of new materials to improve the packaging properties and to extend the shelf life quality of foods. The objective of this study was to formulate, elaborate, select, partially characterize, and evaluate the biological properties of an edible film based on pectin, candelilla wax, and glycerol, added with pomegranate peel polyphenols (PPP). An exploratory design 2<sup>k</sup> Box Hunter and Hunter was made, followed by a Box-Behnken design 3<sup>k</sup> to evaluate the properties of water vapor permeability (WVP) of the film, resulting in the film with 0.75% w/v of pectin, 0.2% w/v of candelilla wax, 0.05% v/v of glycerol and 0.02% w/v of PPP with one of the lowest values of WVP (1.78E<sup>−10</sup> g/m.s.Pa). After characterization, this treatment showed good structural and optical properties and low humidity values compared to a control film. PPP showed the inhibitory capacity for DPPH (61.2%) and ABTS (48.5%) radicals and reducing activity with the reduction of ferric ion (FRAP) reaching a value of 1676.5 mg TE/g PPP.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50138302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of food μPADs with the new tech perspectives and future prospects 食品μPAD的新技术评价及未来展望
eFood Pub Date : 2023-10-19 DOI: 10.1002/efd2.116
Nagihan Okutan Arslan, Levent Trabzon
{"title":"Evaluation of food μPADs with the new tech perspectives and future prospects","authors":"Nagihan Okutan Arslan,&nbsp;Levent Trabzon","doi":"10.1002/efd2.116","DOIUrl":"https://doi.org/10.1002/efd2.116","url":null,"abstract":"<p>Food microfluidic paper-based analytical devices (µPADs) are powerful tools to create total analysis systems and have long been demonstrated to be useful for safety and quality applications. Thanks to new technological innovations food µPADs offer exciting new possibilities. This review introduces how µPADs are obtained from chromatography, filter, or office papers and detect analytes from a food sample. We introduce the most current developments in the use of µPADs with an emphasis on paper types, adapted new technologies, and detection limits. Classifications are also made on food µPADs according to applied innovations and adapted novel technologies. In the first section, simple forms of µPADs for the detection of pathogen, mycotoxin, pesticides, and other food components are discussed with technical details. Then, we introduce multisensing approaches for high throughput analysis and a concise summary will be given. In the case of three-dimensional (3D) µPADs, the use of 3D is discussed and compared to 2D µPADs in terms of its advantageous with the example of a food colorant test device. In the following section, smartphone adoption to µPADs is introduced in detail with eight different assay examples. Centrifugal platform for nickel assay is demonstrated as an enabling approach with shortened assay times by rotational velocity. The potential of user-friendly hybrid devices is also summarized in the last part. Finally, we present an outlook to underline the opportunities created by smartphone-based and intelligent µPADs for food safety and quality with real success perspectives</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.116","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50138301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional exploration of foxtail millet (Setaria italica) in addressing food security and its utilization trends in food system 谷子应对粮食安全的营养探索及其在粮食系统中的利用趋势
eFood Pub Date : 2023-09-27 DOI: 10.1002/efd2.111
Rhythm Kalsi, Jasleen Kaur Bhasin
{"title":"Nutritional exploration of foxtail millet (Setaria italica) in addressing food security and its utilization trends in food system","authors":"Rhythm Kalsi,&nbsp;Jasleen Kaur Bhasin","doi":"10.1002/efd2.111","DOIUrl":"https://doi.org/10.1002/efd2.111","url":null,"abstract":"<p>Millets are recognized as nutritional grains that have been important for preventing the malnutrition and significantly enhancing the human health. Foxtail millet (<i>Setaria italica</i>) is a C4, self pollinating millet species belonging to family <i>Poaceae</i>; acknowledged as Italian millet, Chinese millet or German millet. Being the oldest crops to be cultivated and produced, it is also utilized as a bird feed in African regions of the world. As far as the nutritional content is concerned, it has substantial amounts of carbohydrates (60–65 g), protein (12.3 g), fiber (6 g), minerals (Phosphorous, calcium, iron, zinc, magnesium, sodium), and phytochemicals (Phenols, Ferulic, chlorogenic acids, and p-coumaric, flavonoids, carotenoids, tocopherol, and tocotrienol). Additionally foxtail millet is reported to have anti inflammatory, antioxidant, anticancerous, antihypolipidemic antihyperglycemic properties that may serve well with respect to pharmacological relevance. Apart from the medicinal prospect, its food utilization for making bakery, weaning, fermented as well as extruded goods are studied in the literature. Thus it can be mentioned that foxtail millet has a promising position in strengthening dietary quality and food security of world, thereby functioning as an emissary crop to replenish other economically valuable crops against environmental constraints even while supplying food for people and livestock via biotechnological techniques.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.111","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50145815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curcumin-loaded nanomedicines as therapeutic strategy in malaria management 姜黄素负载纳米药物在疟疾管理中的治疗策略
eFood Pub Date : 2023-09-18 DOI: 10.1002/efd2.113
Ruhul Amin, Chanam Melody Devi, Dona Sarkar, Javad Sharifi-Rad, Eda Sönmez Gürer, Anca Oana Docea, Daniela Calina
{"title":"Curcumin-loaded nanomedicines as therapeutic strategy in malaria management","authors":"Ruhul Amin,&nbsp;Chanam Melody Devi,&nbsp;Dona Sarkar,&nbsp;Javad Sharifi-Rad,&nbsp;Eda Sönmez Gürer,&nbsp;Anca Oana Docea,&nbsp;Daniela Calina","doi":"10.1002/efd2.113","DOIUrl":"https://doi.org/10.1002/efd2.113","url":null,"abstract":"<p>Malaria, a parasitic protozoan disease widespread in tropical climates, is transmitted by <i>Plasmodium</i> spp. Many people are affected by this significant public health disease, which has a high incidence of illness and mortality worldwide. Because drug-resistant parasites are on the rise, there are not enough controls on mosquitoes, and there are not any malaria vaccinations. Malaria is particularly challenging in developing countries. Antimalarial drugs approved by Food and Drug Administration are the main options for combating and preventing malaria; also the control of transmission at the level of mosquitoes is important. Current antimalarial chemotherapeutic therapies have significant clinical flaws such as Plasmodium resistance, the drugs that call for the development of novel drug candidates. To combat malaria, nanotechnology may give a viable alternative that is both more effective and safer than current treatment options. Nanotechnology-based curcumin formulations have proved to overcome the limitations of current therapies in terms of optimum therapeutic benefits, safety, and cost-efficiency, which increases a patient's capacity to adhere to prescribed medicine. The limits of current malaria therapies and the need to employ nanotechnological curcumin to treat malaria were addressed and discussed in this paper.</p>","PeriodicalId":11436,"journal":{"name":"eFood","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/efd2.113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50137475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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