Early Intervention in Psychiatry最新文献

{"title":"“Young People Come to Youth Workers First”: A Mixed Methods Evaluation of the Role of Youth Workers in Youth Psychosis Detection","authors":"Gabriele Gusciute,&nbsp;Ahmed Hassab Errasoul,&nbsp;Sean Naughton,&nbsp;Keith Gaynor,&nbsp;Niall Turner,&nbsp;Mary Clarke","doi":"10.1111/eip.70021","DOIUrl":"https://doi.org/10.1111/eip.70021","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Reducing the duration of untreated psychosis (DUP) is a cornerstone of effective early intervention for psychosis (EIP) services. Delays in help seeking are a significant component of DUP, particularly among youth. Given their role as trusted adults in young people's lives, youth workers are uniquely positioned to play a role in early detection networks. However, their views regarding this remain largely unexamined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study aimed to explore youth workers' perspectives on identifying and responding to psychosis in youth and the training needed to support them in this role.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A sequential-independent mixed methods design was employed. A brief questionnaire was given to youth workers (<i>n</i> = 86) who attended a 1-day EIP training session, followed by semi-structured interviews with a subset of participants (<i>n</i> = 10) 3 months later.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Most participants (98.8%) expressed confidence in recognising psychosis; however, stigma and challenging relationships with mental health services emerged as systemic barriers. Although most participants (98.8%) found the EIP training relevant to their role, they suggested it should form part of a broader mental health curriculum. There was a clear consensus among participants that such training is necessary and should be accessible, practical and actionable.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Youth workers are uniquely positioned in identifying and supporting young people at risk of psychosis, and this study underscores their willingness to take on this role. To best support them, training efforts should focus on trans-diagnostic approaches that enhance mental health literacy, address systemic barriers and promote multidisciplinary partnerships.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70021","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143489820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dynamic Association Between Physical Activity and Psychological Symptoms in Young People With Major Depressive Disorder: An Active and Passive Sensing Longitudinal Cohort Study","authors":"Rosalind Baynham,&nbsp;Andres Camargo,&nbsp;Simon D'Alfonso,&nbsp;Tianyi Zhang,&nbsp;Zamantha Munoz,&nbsp;Pemma Davies,&nbsp;Mario Alvarez-Jimenez,&nbsp;Niels van Berkel,&nbsp;Vassilis Kostakos,&nbsp;Lianne Schmaal,&nbsp;Scott D. Tagliaferri","doi":"10.1111/eip.70018","DOIUrl":"https://doi.org/10.1111/eip.70018","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Physical activity could be associated with psychological symptoms in young people with major depressive disorder (MDD). Using actigraphy and ecological momentary assessment (EMA), we investigated the associations between physical activity and stress, anxiety and positive and negative affect in young people with MDD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Actigraphy and EMA were collected daily in 40 young participants (aged 16–25 years) with MDD over 8 weeks. Multi-level linear mixed models were used to examine within- and between-person daily associations between physical activity and symptoms of stress, depression and positive and negative affect.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Participants with at least 14 days of complete data were included in the analysis (<i>n</i> participants = 22; total days = 598). Typical (defined as average across the assessment period) vigorous physical activity was significantly associated with lower daily stress (<i>β</i>[95% CI] = −0.152 [−0.298, −0.007], <i>p</i> = 0.041) and higher daily positive affect (0.526 [0.061, 0.992], <i>p</i> = 0.028). Variability in daily light (0.004 [0.001, 0.006], <i>p</i> = 0.010) and moderate physical activity (0.004 [0.001, 0.007], <i>p</i> = 0.009) were positively associated with daily stress. Variability in daily light (0.003 [0.001, 0.006], <i>p</i> = 0.018) and moderate physical activity (0.004 [0.001, 0.007], <i>p</i> = 0.011) were positively associated with daily anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Various intensities of daily physical activities were associated with symptoms of stress, anxiety and positive affect in young people with MDD. Future research on larger samples should validate the causal and daily associations between physical activity and psychological symptoms to promote evidence-based behavioural strategies to improve psychological symptoms in young people with MDD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Reported Cognitive Bias in Psychosis: Further Validation of the Cognitive Biases Questionnaire for Psychosis (CBQ-P) and the Davos Assessment of Cognitive Biases (DACOBS) in a Large Iranian Clinical and Non-Clinical Sample","authors":"Mohammad Aminaee,&nbsp;Vahid Khosravani,&nbsp;Seyed Mehdi Samimi Ardestani,&nbsp;Mohammad Reza Fayyazi Bordbar,&nbsp;Mark van der Gaag,&nbsp;Michael Berk","doi":"10.1111/eip.70023","DOIUrl":"https://doi.org/10.1111/eip.70023","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Various factor structures have been suggested for the Davos Assessment of Cognitive Biases (DACOBS) and the Cognitive Biases Questionnaire for Psychosis (CBQ-P), assessing cognitive bias, necessitating additional validation in diverse languages to enhance the validity of the scales.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Persian versions of these scales were validated within an Iranian cohort comprising 1719 individuals: patients with schizophrenia (<i>n</i> = 334) and major depressive disorder (MDD; <i>n</i> = 346) and a non-clinical group (<i>n</i> = 1039). The participants completed both self-report and clinician-administered assessments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The 18-item DACOBS version, comprising four factors, and the single-factor structure of the CBQ-P exhibited the optimal model fit, with confirmed reliability. Both scales showed significant correlations with constructs such as paranoid ideation, social cognition, schizotypal personality and positive symptoms. Additionally, the scales differentiated patients with schizophrenia and individuals at high risk for psychosis from those at low risk or patients with MDD. The CBQ-P and certain subscales of the DACOBS predicted susceptibility to psychosis, positive symptoms and psychosis-related manifestations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The research highlights the validity and reliability of the Persian adaptations of the 18-item DACOBS and the CBQ-P for evaluating cognitive bias in individuals diagnosed with schizophrenia and for identifying individuals at an elevated risk for psychosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143475457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Latent Profile Analysis of Psychosis Symptoms to Examine Distress and Depression as Pathways to Suicide Ideation Among Individuals in an Early Phase of Psychosis Illness","authors":"Lindsay A. Bornheimer,&nbsp;Nicholas M. Brdar,&nbsp;Adrienne Lapidos,&nbsp;Alexandra N. Kelter,&nbsp;Chloe Miner,&nbsp;Andrew Grogan-Kaylor","doi":"10.1111/eip.70013","DOIUrl":"https://doi.org/10.1111/eip.70013","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Suicide rates are high among individuals in first episode psychosis and there is a critical need to better understand drivers of suicide risk to inform treatment efforts. This study identified profiles of psychosis symptoms and examined a mediation model of depression and distress as mechanisms in the relationships between psychosis symptoms and suicide ideation by latent profiles.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were obtained from the Human Connectome Project for Early Psychosis (<i>n</i> = 166) of individuals between 16 and 35 years of age who had onset of affective or non-affective psychosis within 5 years of consent. Data were analysed using Latent Profile Analysis (LPA) and Structural Equation Modelling in MPlus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>LPA revealed the following groups: (1) relatively lower and more balanced levels of symptoms, (2) highest positive and general symptoms and (3) highest negative symptoms. Findings indicated the relationships in the model differed between by LPA groups. Distress and depression functioned as mediators between psychosis symptoms and suicide ideation for Groups 1 and 2.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>A better understanding of the roles that distress and depression play in the relationships between psychosis symptoms and suicide ideation can help inform modifiable targets of early intervention and subsequently decrease risk for suicide.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences Between Users and Professionals in Preferences for Youth Mental Health Service Attributes: A Discrete Choice Experiment","authors":"Eline Wittevrongel,&nbsp;Roselinde Kessels,&nbsp;Geert Everaert,&nbsp;May Vrijens,&nbsp;Marina Danckaerts,&nbsp;Ruud van Winkel","doi":"10.1111/eip.70012","DOIUrl":"https://doi.org/10.1111/eip.70012","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Previous work showed that young people prefer youth-oriented mental health services that offer individual help in houses in urban areas, with short wait times and low costs. The present paper aims to examine which service options professionals working in social welfare or mental health services prefer for addressing young people's mental health needs, comparing their views with those of young people.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Professionals (N = 176) and youth aged 16–24 years (N = 258) participated in a discrete choice experiment (DCE). Panel mixed logit (PML) models were used in both stakeholder groups to ascertain relative differences in attribute weights. We also estimated an overall PML model incorporating the effect of stakeholder group on the attributes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Professionals found the attributes ‘cost’ and ‘wait times’ most relevant to young people's mental health service needs, indicating a preference for services characterised by affordability and minimal wait periods. In contrast, young people adhered more importance to the attribute ‘format’ (individual rather than group therapy). Furthermore, professionals considered a café or youth centre the most suitable location for a service, rather than a house in the city, and they disfavoured care provision by professionals in adult mental health services more than young people did. Finally, the attributes ‘peer support’, ‘opening hours’ and ‘anonymity’ were deemed relevant by professionals but not by young people.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The perspectives of both professionals and young people offer a unique point of view on care provision, stressing the importance of integrating them in preference-based research and service design.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143404648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Remediation for Adolescents With Mental Health Disorders: A Systematic Review and Meta-Analysis","authors":"Caroline East-Richard,&nbsp;Audrey Cayouette,&nbsp;Kelly Allott,&nbsp;Élizabeth Anderson,&nbsp;Frédéric Haesebaert,&nbsp;Matteo Cella,&nbsp;Caroline Cellard","doi":"10.1111/eip.70016","DOIUrl":"https://doi.org/10.1111/eip.70016","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The effects of cognitive remediation therapy (CRT) in adults with mental health disorders have been widely documented, but its effects in adolescents with mental health disorders remain poorly understood. This review aims to (1) determine the effects of CRT on cognition, symptoms and functioning for adolescents with mental health disorders and (2) evaluate the methodological quality of studies on CRT.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic review and meta-analysis were conducted of randomised controlled trials of CRT involving adolescents with mental health disorders. Searches were conducted in databases for studies pertaining to CRT effects on cognition, social functioning and clinical symptoms. Methodological quality was assessed using the Clinical Trials Assessment Measure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fourteen studies (<i>N</i> = 14) were included, with 11 independent samples (<i>k</i> = 11, 592 participants). Participants had various mental health disorders. CRT showed a small significant effect on cognition (<i>g</i> = 0.14, <i>p</i> = 0.02), particularly on processing speed, working memory and episodic memory. No significant effects were found for clinical symptoms (<i>g</i> = 0.04, <i>p</i> = 0.58) and social functioning (g = 0.06, <i>p</i> = 0.39). Methodological quality of included studies was variable, ranging from poor to good quality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Included studies showed a small significant effect of CRT on cognition, and non-significant effects on clinical symptoms and social functioning in adolescents with mental health disorders. The lack of effects may be partly explained by limitations in the methodology of included studies. A critical analysis of current studies is presented and recommendations of core techniques to consider for future CRT studies are discussed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suicidality in Primary Care, Youth Mental Health Services: Prevalence, Risk Factors and Implications for Practice","authors":"Sabina Albrecht,&nbsp;Debra Rickwood,&nbsp;Nic Telford,&nbsp;Georgia Privitera,&nbsp;Nicola Palfrey","doi":"10.1111/eip.70020","DOIUrl":"https://doi.org/10.1111/eip.70020","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Youth suicide is a concern worldwide, and suicidality—the presence of suicidal ideation or intent—is a critical risk for youth mental health services. This study aimed to determine the prevalence of suicidality in primary care, youth mental health services, along with its correlates and the course of treatment offered to clients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Routinely collected data from Australia's <i>headspace</i> National Youth Mental Health Foundation, which has over 160 centres across Australia providing mental health care to young people aged 12–25 years, were analysed for new clients who started and completed their first episode of care between 1 July 2022 and 30 June 2023. This included 30 437 young people/episodes of care and 74 393 occasions of service.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results showed that suicidality was evident in almost one-quarter of young people, although it was rarely reported as a primary presenting issue. When present, it was usually identified at first visit. Those most at risk were young people in unstable accommodation, who identified as LGBTIQA+ or who were indigenous.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The findings show that suicidality should be anticipated in young people presenting to primary care mental health settings, and youth services need to be able to competently deal with suicide risk rather than using this as exclusion criteria.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143380859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Client Perspectives on Addressing Intimacy, Romance and Sexuality in Early Psychosis Intervention Programmes","authors":"Stephanie M. Woolridge,&nbsp;Emma Wilkinson,&nbsp;Isabelle Hau,&nbsp;Chloe A. Stewart,&nbsp;Savie Edirisinghe,&nbsp;Robert Aidelbaum,&nbsp;Michael W. Best,&nbsp;Christopher R. Bowie","doi":"10.1111/eip.70014","DOIUrl":"https://doi.org/10.1111/eip.70014","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study investigated the perspectives of clients in early psychosis intervention programmes regarding the types, quality and relevance of information they desire and receive, particularly related to intimacy, romance and sexuality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants (<i>N</i> = 35) rated the degree to which they desired and received information on topics related to treatment and recovery, as well as the quality and importance of that information.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between 25% and 50% of participants desired information on friendships, sexual functioning, sexual desire, sexual risk factors and romantic relationships. Less than half of participants who wanted information on romantic relationships, friendships, sexual desire and sexual functioning received this information. When this information was provided, however, participants reported it to be of high quality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Findings demonstrate that intimacy, romance and sexuality remain areas of need that are relevant to recovery for people with psychosis, yet they continue to be insufficiently addressed in healthcare settings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143389138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying Preliminary Risk Profiles for Dissociation in 16- to 25-Year-Olds Using Machine Learning","authors":"Roberta McGuinness,&nbsp;Daniel Herring,&nbsp;Xinyi Wu,&nbsp;Maryam Almandi,&nbsp;Daveena Bhangu,&nbsp;Lucia Collinson,&nbsp;Xiaocheng Shang,&nbsp;Emma Černis","doi":"10.1111/eip.70015","DOIUrl":"https://doi.org/10.1111/eip.70015","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Dissociation is associated with clinical severity, increased risk of suicide and self-harm, and disproportionately affects adolescents and young adults. Whilst evidence indicates multiple factors contribute to dissociative experiences, a multi-factorial explanation of increased risk for dissociation has yet to be achieved.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used multiple regression to investigate the relative influence of five plausible risk factors (childhood trauma, loneliness, marginalisation, socio-economic status, and everyday stress), and machine learning to generate tentative high-risk profiles for ‘felt sense of anomaly’ dissociation (FSA-dissociation) using cross-sectional online survey data from 2384 UK-based 16- to 25-year-olds.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Multiple regression indicated that four risk factors significantly contributed to FSA-dissociation, with relative order of contribution: everyday stress, childhood trauma, loneliness and marginalisation. Exploratory analysis using machine learning suggested dissociation results from a complex interplay between interpersonal, contextual, and intrapersonal pressures: alongside marginalisation and childhood trauma, negative self-concept and depression were important in younger (16–20 years), and anxiety and maladaptive emotion regulation in older (21–25 years) respondents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Validation of these findings could inform clinical assessment, and prevention and outreach efforts, improving the under-recognition of dissociation in mainstream services.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eip.70015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143380035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial High-Risk for Psychosis and Bipolar Disorder Amongst Youth in an Academic Healthcare System: A Real-World Assessment of Clinical Characteristics and Implications for Clinical Care","authors":"Halide Bilge Türközer,&nbsp;Perihan Esra Guvenek-Cokol,&nbsp;Zachary B. Millman,&nbsp;Daniel Dickstein,&nbsp;Dost Öngür","doi":"10.1111/eip.70019","DOIUrl":"https://doi.org/10.1111/eip.70019","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Family history is amongst the most significant risk factors for psychotic and bipolar disorders. Despite being clearly defined, easily and early identifiable, familial high-risk status is minimally accounted for in mainstream prevention paradigms. This study reports on the demographics and clinical characteristics of youth with a first-degree relative affected by psychotic or bipolar disorders within a large academic healthcare system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>In this quality improvement study, using electronic medical records, the authors examined demographics, psychiatric and medical diagnoses, substance use, service utilisation, and psychotropic medication use in children, adolescents and young adults (age 24 or younger) with and without a family history of psychotic or bipolar disorders within the Mass General Brigham (MGB) healthcare system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Family history-positive (FHP) youth demonstrated markedly higher rates of psychiatric problems (57.8%) compared to family history-negative (FHN) youth (8.5%), including higher rates of psychotic and bipolar disorders, as well as anxiety disorders and depression. FHP youth also had more frequent psychotropic medication use and medical problems. Additionally, FHP youth reported higher cannabis and alcohol use, along with higher rates of suicidal ideation and trauma. Despite this, only 4% of FHP youth visited an MGB psychiatry or psychology department within the six months preceding the analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>FHP youth constitute a distinct and practically identifiable risk cohort within a large academic healthcare system. Increased psychiatric and medical problems coupled with more prevalent risk factors amongst familial high-risk youth highlight the need for tailored clinical programmes to achieve both primary and secondary prevention.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11385,"journal":{"name":"Early Intervention in Psychiatry","volume":"19 2","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143380036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}