Digestive Diseases and Sciences最新文献

{"title":"Another commentary on Our Article, \"Outcomes of Acute Pancreatitis in Lean Versus Non-lean MASLD Patients: A Nationwide Analysis\".","authors":"Prince A Ameyaw, Sarpong Boateng, Yussif Issaka, Erica S Ackah, Amita A Kasar, Yazan A Al-Ajlouni, Basile Njei","doi":"10.1007/s10620-025-09406-z","DOIUrl":"https://doi.org/10.1007/s10620-025-09406-z","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Choledochoduodenostomy Versus Gallbladder Drainage for Malignant Biliary Obstruction: A Propensity Score Matched Study.","authors":"Noppachai Siranart, Christopher C Thompson, Marvin Ryou, Steven N Steinway","doi":"10.1007/s10620-025-09417-w","DOIUrl":"https://doi.org/10.1007/s10620-025-09417-w","url":null,"abstract":"<p><strong>Introduction: </strong>Endoscopic ultrasound-guided gallbladder drainage (EUS-GB) is an emerging alternative to choledochoduodenostomy (EUS-CBD) for malignant distal biliary obstruction (MDBO), particularly when conventional access is not feasible.</p><p><strong>Methods: </strong>We conducted a multicenter, retrospective study of patients undergoing EUS-GB or EUS-CBD for MDBO between January 2015 and October 2024. Primary outcomes were technical and clinical success. Secondary outcomes included procedural time, 6-month reintervention, adverse events (AEs), and all-cause mortality. Propensity score matching (PSM) was used to adjust for baseline differences.</p><p><strong>Results: </strong>Eighty-two patients were included (22 EUS-GB, 60 EUS-CBD). Technical success was comparable between groups (95.5% vs. 96.7%). EUS-GB was used as salvage in 50% of cases when EUS-CBD was not feasible, with a 90.9% technical success rate. PSM yielded 21 matched pairs. After propensity score matching, clinical success was similar (95.2% EUS-GB vs. 85.7% EUS-CBD, p = 0.61). EUS-GB had significantly lower 6-month reintervention (4.8% vs. 23.8%, p = 0.004) and stent-related complications (0% vs. 18.9%). Adverse event rates and all-cause mortality were similar. Median follow-up was 116 days (IQR: 51-300). In the EUS-GB group, pre-procedural cystic duct patency predicted clinical success (94.1%).</p><p><strong>Conclusion: </strong>EUS-GB is a technically effective and clinically comparable alternative to EUS-CDS for MDBO, with significantly fewer reinterventions and stent-related complications. When cystic duct patency is confirmed on imaging, EUS-GB may be considered as a primary approach or salvage strategy for biliary drainage in MDBO.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopy Unit Implementation of a Sealed In-Room Air Purifier with Ultraviolet Irradiation Reduces Bacterial and Airborne Particle Levels.","authors":"Monique T Barakat, Linda D Lee, Natalie Conti, Timothy Angelotti","doi":"10.1007/s10620-025-09388-y","DOIUrl":"https://doi.org/10.1007/s10620-025-09388-y","url":null,"abstract":"<p><strong>Purpose: </strong>There is a need for enhanced air quality in healthcare settings, particularly in areas with high levels of airborne particles and complex room layouts. This study evaluated the impact of germicidal ultraviolet air purification devices (GUVAPD) on bacterial contamination and airborne particle levels in endoscopic procedural rooms.</p><p><strong>Methods: </strong>We compared two endoscopy rooms and assessed whether GUVAPDs would further improve air quality above standard cleaning protocols. We compared an experimental room equipped with four germicidal ultraviolet chambers (Clean Air Unit, UV Angel) and a control room; both rooms performed similar endoscopic procedures. Microbial air and settled surface samples were collected, and airborne particle counts (0.3 and 2.5 um) were performed before and after the installation of GUVAPD, using standard techniques.</p><p><strong>Results: </strong>A significant 79% reduction of airborne bacterial colony-forming units (CFUs) from 130.8 to 27.2 CFUs (p < 0.0001) and a 68% reduction in settled surface bacterial CFUs from 10.2 to 5.7 CFUs (p = 0.016) were observed following installation of GUVPADs. Additionally, particulate matter measurements indicated a particle reduction of 47% and 75% (0.3 and 2.5 micron, respectively) after installation of GUVAPDs.</p><p><strong>Conclusions: </strong>These findings demonstrate that supplemental UV air treatment administered via GUVAPD effectively reduced both microbial and particulate contaminants in a complex room environment. Integrating GUVAPDs into current infection control strategies holds promising potential for improving patient and staff safety. Future research should explore the long-term effects and applicability of these systems in diverse clinical settings to further establish their efficacy in mitigating infections.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145136843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Disorders Among Patients Diagnosed with Chronic Pancreatitis: A Systematic Review.","authors":"Ansuman Panigrahi, Jewel Ipsita Sahani, Swati Sambita Mohanty, Sanghamitra Pati","doi":"10.1007/s10620-025-09410-3","DOIUrl":"https://doi.org/10.1007/s10620-025-09410-3","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic pancreatitis is associated with various sleep disorders, impacting patients' quality of life. This systematic review aimed to synthesize existing evidence on the prevalence, associated risk factors, and health-related quality of life impacts of sleep disorders among patients diagnosed with chronic pancreatitis.</p><p><strong>Methods: </strong>We conducted a systematic search of PubMed, Embase, Scopus, Web of Science, ScienceDirect, ProQuest, EBSCO, Google Scholar, and Shodhganga for studies published between January 1, 1990 and May 31, 2024, using predefined keywords and MeSH terms related to chronic pancreatitis, sleep disorders, and sleep quality, following our PROSPERO-registered protocol. The review exclusively focused on English-published studies because of limited resources, potentially introducing language bias. Gray literature was explored via Shodhganga and Google Scholar. The review was registered with PROSPERO (CRD42024547787). Eligible studies included those that investigated sleep disorders or sleep quality among patients diagnosed with chronic pancreatitis. The methodological quality of all included studies was appraised using the Joanna Briggs Institute critical appraisal checklist. Study selection and data extraction were performed independently by three reviewers, with discrepancies resolved by consensus or adjudication to reduce selection bias.</p><p><strong>Results: </strong>Out of 995 records, 9 studies were included after screening. These comprised six cross-sectional studies, one prospective cohort, and two retrospective cohort studies. Studies reported sleep disorder prevalence ranging from 33 to 81.6%. The Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, and Insomnia Severity Index served as the primary assessment tools across the studies. Most studies demonstrated high methodological quality, with eight scoring ≥ 7 on the JBI checklist.</p><p><strong>Conclusion: </strong>This systematic review revealed a high prevalence of sleep disorders in patients with chronic pancreatitis, underscoring the poor sleep quality in this population. These disturbances adversely affect the overall quality of life, emphasizing the need to integrate sleep management into comprehensive care.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EUS-Guided Diagnosis of Hepatic Tuberculosis Presenting as Postoperative Fistula.","authors":"Ritesh Acharya, Raghuraman Soundararajan, Parikshaa Gupta, Rajesh Gupta, Surinder Singh Rana","doi":"10.1007/s10620-025-09421-0","DOIUrl":"https://doi.org/10.1007/s10620-025-09421-0","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Endoscopic Presentation of Sigmoid Colon MALT Lymphoma.","authors":"Jia-Min Wang, Li-Ming Wen, Li Wang, Jia-Min Qin, Zhen Tang","doi":"10.1007/s10620-025-09418-9","DOIUrl":"https://doi.org/10.1007/s10620-025-09418-9","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Endoscopic Ultrasound-Guided Laparoscopic Removal of Foreign Body That Penetrated the Stomach.","authors":"Jun Yao, Wenbiao Chen, Yiteng Meng","doi":"10.1007/s10620-025-09403-2","DOIUrl":"https://doi.org/10.1007/s10620-025-09403-2","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic Vertebral Osteophyte as an Unusual Cause of Dysphagia.","authors":"Rui Zhong, Baijun Chen, Jun Li, Chen Bai, Kui Zhao","doi":"10.1007/s10620-025-09423-y","DOIUrl":"https://doi.org/10.1007/s10620-025-09423-y","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexual Health and STI Counseling Is Critical but Often Overlooked in IBD.","authors":"Alexander Goldowsky, Andrew Eidelberg, Grace Geeganage, Ajay Gade, Oriana Pando, Alessandra Saraga, Tina Deyhim, Konstantinos Papamichael, Daniel Wong, Kristen Crowell, Sarah Flier, Kira L Newman, Adam S Cheifetz, Sarah Ballou, Loren G Rabinowitz","doi":"10.1007/s10620-025-09396-y","DOIUrl":"https://doi.org/10.1007/s10620-025-09396-y","url":null,"abstract":"<p><strong>Background: </strong>Sexual health counseling (SHC) is a critical aspect of inflammatory bowel disease (IBD) care. Less is known about sexual health counseling in patients who identify as members of a sexual or gender minority (SGM) group.</p><p><strong>Aims: </strong>This study aims to characterize patient-reported sexual health counseling in SGM vs. non-SGM patients with IBD.</p><p><strong>Methods: </strong>We conducted an anonymous, cross-sectional survey of patients over 18 years old with IBD, currently receiving care at a large, tertiary care IBD center. Data collection included demographics, IBD history, and patient recall of SHC. Patients who self-identified as SGM were compared to non-SGM patients, with subgroup analyses by sex assigned at birth. Means were compared using t tests and percentages compared using chi-square analysis.</p><p><strong>Results: </strong>A total of 162 patients (41 SGM and 121 non-SGM) completed the survey. Both groups reported IBD impacted their sexual practices (ranging from 44% non-SGM men to 64% SGM women). SGM patients were more likely to report that their gastroenterologist asked about sexual health compared to non-SGM patients (p < .005). Importantly, 31% of respondents reported seeking SHC from their gastroenterologist (GI), placing GIs among the top sources of information regarding sexual health in this cohort.</p><p><strong>Conclusion: </strong>Most study participants reported that IBD has impacted their sexual practices. SHC rates were low in all study groups despite GI providers being a primary source of information. Clearer recommendations on aspects of SHC could improve quality of care for both SGM and non-SGM patients with IBD.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diet in Ulcerative Colitis: A Narrative Review of Its Role in Pathogenesis and Treatment.","authors":"Fares Jamal, Nour B Odeh, Mayar Husam Iyad Alatout, Muhammad Ali Khan, Syed B Pasha, Talha A Malik","doi":"10.1007/s10620-025-09387-z","DOIUrl":"https://doi.org/10.1007/s10620-025-09387-z","url":null,"abstract":"<p><p>Ulcerative colitis (UC) is a chronic inflammatory bowel disease influenced by genetic, immune, microbial, and environmental factors, with diet emerging as a key modifiable element. This narrative review examines how specific macronutrients, food additives, and dietary patterns affect UC pathogenesis, symptom control, and clinical outcomes. High intake of saturated fats, red and processed meats, and ultra-processed foods promotes dysbiosis and mucosal inflammation, while diets rich in fiber, resistant starches, and omega-3 fatty acids support gut barrier integrity and exert anti-inflammatory effects. The Mediterranean diet is associated with reduced disease activity, improved microbial diversity, and a lower incidence of pouchitis. Although the low-FODMAP diet can alleviate functional gastrointestinal symptoms, it lacks evidence for reducing inflammation and may adversely impact beneficial bacteria. Parenteral nutrition remains a valuable intervention in select cases with compromised oral or enteral intake. Micronutrient deficiencies, including iron, vitamin D, zinc, and magnesium, are common and should be routinely monitored. A personalized, dietitian-led approach that incorporates cultural preferences and digital tools may enhance dietary adherence and disease management. Further research is needed to define long-term effects of dietary interventions and integrate nutrition more fully into UC treatment algorithms.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}