Dermatology Research and Practice最新文献

{"title":"The Effect of Whey Protein Supplements on Acne Vulgaris among Male Adolescents and Young Adults: A Case-Control Study from North of Jordan","authors":"J. Muhaidat, Almutazballlah Qablan, Faris Gharaibeh, Ghaith H. Albataineh, Nour Abdo, D. Alshiyab, Firas A. Al-qarqaz","doi":"10.1155/2024/2158229","DOIUrl":"https://doi.org/10.1155/2024/2158229","url":null,"abstract":"Background Young people and athletes willing to gain muscle mass and strength are likely to consume whey protein supplements. The effect of milk as a dietary source of whey protein on acne is still controversial. At the same time, a few studies have suggested an acnegenic impact of whey protein supplements. Objectives To examine the association of whey protein supplements on acne risk among male adolescents and young adults. Materials and Methods 201 male teenagers and young adults attending fitness centers in Irbid/Jordan were involved in an observational case-control research; those with acne were deemed cases, and those without acne were considered controls. The primary outcome was a comparison of the proportion of participants in each group who consumed whey protein supplements within the previous three months. Results 100 acne-afflicted participants were compared to 101 healthy controls with similar demographics, including age, body mass index, educational level, and smoking habits, as well as intake of vitamin B12, corticosteroids, and anabolic steroids. However, considerably more participants in the acne group (47%) were taking whey protein supplements than in the control group (27.7%) (p=0.0047). The significance of this difference was maintained after multivariate analysis. Conclusion This case-control study provides evidence of a positive association between whey protein consumption and acne risk.","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"64 4","pages":""},"PeriodicalIF":1.5,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140725022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous T-Cell Lymphoma and Microbiota: Etiopathogenesis and Potential New Therapeutic Targets.","authors":"Daniel Rodríguez Baeza, Lía Bejarano Antonio, Marta González de Arriba, José Antonio Picó-Monllor, Javier Cañueto, Vicente Navarro-Lopez","doi":"10.1155/2024/9919225","DOIUrl":"10.1155/2024/9919225","url":null,"abstract":"<p><strong>Objective: </strong>To review the scientific literature related to human microbiota and cutaneous T-cell lymphoma. <i>Methodology</i>. An exploratory and systematic review of the articles retrieved from the bibliographic databases MEDLINE (PubMed), Embase, The Cochrane Library, and Scopus, published in the last 10 years with the following descriptors: \"lymphoma, T-cell, cutaneous,\" \"microbiota,\" \"Mycosis Fungoides,\" \"Sézary Syndrome,\" \"lymphoma, primary cutaneous anaplastic large cell,\" \"Lymphomatoid Papulosis\" and \"Microbiota,\" \"microbiota,\" \"Microbial Community,\" and \"Microbial Communities.\"</p><p><strong>Results: </strong>Of the 87 references retrieved, after applying the inclusion and exclusion criteria, 21 articles were selected. Most studies linking cutaneous T-cell lymphoma and the microbiota focus on the cutaneous microbiome, with <i>Staphylococcus aureus</i> being the main related agent. Skin colonization by this bacterium could be involved in the hyperactivation of the STAT3 inflammatory pathway and in the overproduction of IL-17, both of which are widely related to the development of more aggressive and advanced forms of cutaneous T-cell lymphoma. We also found evidence of a possible relationship between intestinal dysbiosis and the development of cutaneous T-cell lymphoma, observing a decrease in taxonomic variability and an increase in certain genera such as <i>Prevotella</i> in the intestinal microbiome of patients with cutaneous T-cell lymphoma. The possible etiopathogenic mechanism underlying this relationship could be explained by an increase in systemic cytokine release, promoting the hyperactivation of STAT3 at the skin level.</p><p><strong>Conclusion: </strong>There appears to be a relationship between cutaneous T-cell lymphoma and the cutaneous and intestinal microbiome, as well as a possible pathophysiological pathway involved. The possible modulation of the cutaneous and intestinal microbiome or the action on the signaling inflammatory pathway, using pharmacological tools such as JAK inhibitors or IL-17 inhibitors in the latter case, could open the possibility for future therapeutic studies for cutaneous T-cell lymphoma.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2024 ","pages":"9919225"},"PeriodicalIF":1.5,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10904680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140021107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facial Papulopustular Eruption during the COVID-19 Pandemic in Patients Treated with EGFR Inhibitors.","authors":"Eleonora De Luca, Pietro Sollena, Lucia Di Nardo, Ettore D'Argento, Emanuele Vita, Giampaolo Tortora, Ketty Peris","doi":"10.1155/2024/8859032","DOIUrl":"10.1155/2024/8859032","url":null,"abstract":"<p><p>Papulopustular rash (PPR) is the most frequent cutaneous adverse event during treatment with epidermal growth factor receptor inhibitors (EGFRis). Although often mild in severity, it can impair patients' quality of life and may also be a reason for discontinuing or changing the dose of the antineoplastic treatment. During COVID-19 pandemics, the use of surgical masks drastically increased and it had an impact on the face skin microenvironment, favoring the worsening of dermatological pathologies. We reported the relapse of PPR in patients treated with EGFR inhibitors who consistently wore face masks (>6 hours/day). All the patients developed the PPR within 6 months of starting mask use. Compared to the PPR occurred previously, after mask use, the skin eruption was more severe and affected mainly those regions of the face which came into contact with the mask. Patients received topical or systemic treatment, obtaining complete response in 65.7% of the cases. The establishment of an early treatment for the PPR allows continuing the oncologic treatment, without any suspension which could result in a decreased oncologic outcome. In conclusion, when using these devices, it is recommended to use special precautions, particularly in oncologic patients, by using a daily prophylactic skincare and replacing masks regularly with regular and frequent breaks.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2024 ","pages":"8859032"},"PeriodicalIF":1.5,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herpes Zoster after COVID-19 Infection or Vaccination: A Prospective Cohort Study in a Tertiary Dermatology Clinic","authors":"C. Leeyaphan, Pattriya Jirawattanadon, S. Bunyaratavej, Waratchaya Panjapakkul, Thrit Hutachoke, Yanisorn Nanchaipruek, Phumithep Phumariyapong","doi":"10.1155/2023/2206498","DOIUrl":"https://doi.org/10.1155/2023/2206498","url":null,"abstract":"Background. Herpes zoster (HZ) has been observed to occur after COVID-19 infection and vaccination; however, knowledge regarding the demographic data, clinical presentations, and treatment outcomes of HZ is limited. Objective. To compare the demographic data, clinical manifestations, treatments, and outcomes of patients with and without HZ within 14 days of COVID-19 infection or vaccination. Methods. This prospective cohort study involving patients diagnosed with cutaneous HZ was conducted at a dermatology clinic from October 2021 to January 2023. Results. Among a total of 232 patients with HZ, the median age was 62.0 years and 59.1% were female. HZ developed in 23 (9.9%) and four (1.7%) patients after COVID-19 vaccination and infection, respectively. The mean duration from vaccination and the median duration from infection to HZ onset were 5.7 and 8.5 days, respectively. The proportion of female patients was significantly higher in the group of patients with COVID-19 vaccination or infection than in those without such a history (P = 0.035). Patients who developed HZ following the recent COVID-19 infection had a median age of 42.5 years, which was lower than that of the other groups. Dissemination occurred in 8.7% of the patients after COVID-19 vaccination. HZ recurrence was reported in five cases, of which 80% had been vaccinated or infected with COVID-19 during the previous 21 days. All patients had similar durations of antiviral treatment, crust-off time, and duration of neuralgia. Conclusions. HZ after COVID-19 vaccination is more frequently observed in females, while HZ after COVID-19 infection tends to occur in younger patients. Disseminated HZ is more common in patients recently vaccinated against COVID-19. COVID-19 vaccination or infection may trigger recurrent HZ infection.","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"97 17","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139131583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing Granuloma Annulare in 73 Pediatric Patients","authors":"Ania Stolarczyk, F. Bawany, Simon Hernandez, Glynis A. Scott, M. Cordisco","doi":"10.1155/2023/9267263","DOIUrl":"https://doi.org/10.1155/2023/9267263","url":null,"abstract":"Background. Granuloma annulare (GA) is a common, benign, idiopathic inflammatory dermatosis. Aside from case reports and small studies, there are limited data about the characteristics of GA in children. Objective. This study aimed to better characterize the epidemiologic and clinical features, triggering factors, disease associations, and outcomes of GA in the pediatric population. Methods. We conducted a retrospective study of 73 pediatric patients diagnosed with GA at the University of Rochester Medical Center over a 7-year period. Results. The most common subtype was localized GA (71.2%, n = 52), followed by subcutaneous (also known as “deep GA”; 16.4%, n = 12) and generalized (12.3%, n = 9) subtypes. Over 90% of patients had idiopathic GA, with the remaining patients reporting viral infection or trauma as triggers. Half of the patients studied had comorbid conditions, most frequently atopic dermatitis (17.8%, n = 13), obesity (9.59%, n = 7), asthma (6.85%, n = 5), and allergic rhinitis (6.85%, n = 5). The median duration of the disease was 11.00 months (interquartile range (IQR) 15.75 months); generalized GA had the shortest duration (median 10.00 months, IQR 15.50 months), while subcutaneous GA had the longest duration (median 12.00 months and IQR 29.00 months). Although recurrence rates for subcutaneous and generalized GA were high at 45.5% and 33.3%, respectively, most patients achieved clearance or improvement with treatment. Conclusion. Most cases of GA in our study were idiopathic, with no clear differences between GA subtypes and associated comorbidities. Topical steroids were the most prescribed treatment with mixed efficacy.","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"7 9","pages":""},"PeriodicalIF":1.5,"publicationDate":"2023-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Three Types of Moisturizers on Senile Dry Skin: A Randomized Controlled Pilot Trial.","authors":"Miku Aoki,&nbsp;Natsuki Hata,&nbsp;Junko Yotsuya","doi":"10.1155/2023/1809109","DOIUrl":"10.1155/2023/1809109","url":null,"abstract":"<p><strong>Background: </strong>For dry skin, the application of a hypoallergenic moisturizer twice daily is recommended in elderly individuals. However, it is not known which is the most effective and appropriate moisturizer among the commercially available moisturizers.</p><p><strong>Aims: </strong>In this study, we aimed to investigate the efficacy of the three widely used moisturizers for the treatment of senile dry skin. <i>Patients/Methods</i>. This interventional study involved elderly individuals aged >65 years who were living in a nursing home. The participants were randomly divided into the interventional (moisturizers A, B, and C) and conventional care groups. Moisturizers A, B, and C were applied on the skin of each member of the three intervention groups twice daily for 8 weeks. The water content of the stratum corneum and transepidermal water loss (TEWL) were evaluated before and after the intervention. Changes in these parameters among the groups were compared using two-way analysis of variance and a posthoc test.</p><p><strong>Results: </strong>Moisturizers A, B, and C and conventional care groups comprised six, seven, five, and four participants, respectively. The water content of the stratum corneum was significantly higher in the moisturizer A (<i>p</i> = 0.01) and B (<i>p</i> = 0.047) groups than in the conventional care group. There was no significant difference in TEWL among the groups.</p><p><strong>Conclusions: </strong>In terms of the appearance of the skin, white powder and small scales were both reduced in group A. Taken together with the water content, this was considered a clinically significant change.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2023 ","pages":"1809109"},"PeriodicalIF":1.5,"publicationDate":"2023-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9910033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential Expression of Claudin 1 and 4 in Basal Cell Carcinoma of the Skin.","authors":"T Nakazawa,&nbsp;A Hasegawa,&nbsp;T Nagasaka,&nbsp;K Yoshida,&nbsp;F Guo,&nbsp;D Wu,&nbsp;K Hiroshima,&nbsp;M Takeuchi","doi":"10.1155/2023/9936551","DOIUrl":"https://doi.org/10.1155/2023/9936551","url":null,"abstract":"<p><p>Basal cell carcinoma (BCC) is the most common human malignancy. The biological behavior of this entity is remarkably indolent. Claudin plays an important role in tight junctions, regulating paracellular passage of variable substance including growth factors and maintaining the polarity of epithelia. Up- or downregulated claudin expression has been reported in many cancers. Nevertheless, claudin expression in BCC of the skin remains unclear. We therefore examined the status of claudin 1 and 4 expressions in BCC and adjacent normal skin by immunohistochemistry (IHC). Our IHC results demonstrated high claudin 1 expression and low claudin 4 expression in 33 of 34 lower-grade BCCs. In lower-grade BCC, claudin 1 was increased and claudin 4 was decreased compared with the normal skin. Claudin 1 was inclined to be highly expressed in the membrane and cytoplasm of tumour cells in the periphery of tumour nest. Conversely, almost all lower-grade BCCs (33/34) and one of two higher-grade BCC lacked or showed focal positivity for claudin 4. These results imply that the expression pattern is characteristics of lower-risk BCC. Interestingly, one of the two higher-grade BCCs demonstrated the converse expression patterns of claudins, with decreased claudin 1 and increased claudin 4. The combination of immunohistochemical claudin 1 and 4 expression may offer a useful ancillary tool for the pathological diagnosis of BCC. Furthermore, membranous and intracellular claudins may present future therapeutic targets for uncontrollable BCC.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2023 ","pages":"9936551"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10584280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glove-Induced Hand Dermatitis: A Study in Healthcare Workers during COVID-19 Pandemic in Indonesia.","authors":"Cita Rosita Sigit Prakoeswa,&nbsp;Damayanti,&nbsp;Sylvia Anggraeni,&nbsp;Menul Ayu Umborowati,&nbsp;Fajar Waskito,&nbsp;Niken Indrastuti,&nbsp;Sri Awalia Febriana,&nbsp;Agnes Rosarina Prita Sari,&nbsp;Kristo Alberto Nababan,&nbsp;Cut Putri Hazlianda,&nbsp;Nopriyati,&nbsp;Windy Keumala Budianti,&nbsp;Miranti Pangastuti,&nbsp;Faridha Ilyas,&nbsp;Agnes Kartini,&nbsp;Nurwestu Rusetiyanti,&nbsp;Ika Anggraini,&nbsp;Idrianti Idrus,&nbsp;Herwinda Brahmanti,&nbsp;Gardenia Akhyar","doi":"10.1155/2023/6600382","DOIUrl":"https://doi.org/10.1155/2023/6600382","url":null,"abstract":"<p><p>Skin damage among healthcare workers has been reported by many centers around the world. Occupational hand dermatitis is one of the most commonly known occupational skin diseases and a socially significant health issue. The use of gloves is one of the risk factors for the occurrence and/or aggravation of hand dermatitis. This cross-sectional study involved healthcare workers in 14 referral hospitals for COVID-19 throughout Indonesia. Questionnaires were distributed to the participants, which consisted of the subject's characteristics, glove-related skin problems, history of glove use, and clinical history. This study involved a total of 845 healthcare workers. Approximately 156 healthcare workers (18.46%) had glove-induced hand dermatitis during the pandemic. Itchy skin was the most common symptom (44.23%), and the palm was the most frequently complained area (48.72%). There was a significant association between glove use and glove-induced hand dermatitis among healthcare workers. In particular, equal to or more than 2 hours per day of glove use was significantly associated with hand dermatitis. Glove-induced hand dermatitis also had a significant association with the subject's history of atopic dermatitis and previous history of hand dermatitis. The use of gloves by healthcare workers should be considered carefully, especially in individuals at increased risk, including those who use gloves for 2 hours or more per day and those who have a history of atopic or hand dermatitis, in order to prevent the incidence of glove-induced hand dermatitis among healthcare workers, as well as to provide a safe working environment.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2023 ","pages":"6600382"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10412120/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10349976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dupilumab: Direct Cost and Clinical Evaluation in Patients with Atopic Dermatitis.","authors":"Marco Ferrari,&nbsp;Matthew G Donadu,&nbsp;Gabriele Biondi,&nbsp;Laura Saderi,&nbsp;Federica Sucato,&nbsp;Maria A Montesu,&nbsp;Paola Ruggiu,&nbsp;Paola Merella,&nbsp;Carla Chessa,&nbsp;Angela Sias,&nbsp;Gabriella Carmelita,&nbsp;Vittorio Mazzarello,&nbsp;Giovanni Sotgiu,&nbsp;Satta Rosanna","doi":"10.1155/2023/4592087","DOIUrl":"https://doi.org/10.1155/2023/4592087","url":null,"abstract":"<p><p>Health care spending in Italy is high and continues to increase; assessing the long-term health and economic outcomes of new therapies is essential. Atopic dermatitis (AD) is a chronic, pruritic, immune-mediated inflammatory dermatosis, a clinical condition that significantly affects patients' quality of life at a high cost and requires continuous care. This retrospective study aimed to assess the direct cost and adverse drug reactions (ADRs) of Dupilumab and patients' clinical outcomes. All AD patients treated with Dupilumab at the Sassari University Hospital, Italy, between January 2019 and December 2021 were included. Eczema Area Severity Index, Dermatology Life Quality Index, and Itch Numeric Rating Scale scores were measured. ADRs and drug expenses were analyzed. A statistically significant posttreatment improvement was observed for all the indices measured: EASI (<i>P</i> < 0.0001), DLQI (<i>P</i> < 0.0001), NRS (<i>P</i> < 0.0001). The total expenditure for Dupilumab, in the observed period, amounted to € 589.748,66 for 1358 doses, and a positive correlation was shown between annual expenditure and delta percentage of variation pre- and posttreatment for the clinical parameters evaluated.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2023 ","pages":"4592087"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9946764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9342391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic Characteristics in the Fingers and Other Superficial Glomus Tumours.","authors":"Noboru Takanashi,&nbsp;Satomi Asai,&nbsp;Yoko Ogase,&nbsp;Akiko Fujii,&nbsp;Haruyo Atsumi,&nbsp;Mika Doi,&nbsp;Nobue Kumaki,&nbsp;Tomotaka Mabuchi,&nbsp;Hayato Miyachi","doi":"10.1155/2023/7126799","DOIUrl":"https://doi.org/10.1155/2023/7126799","url":null,"abstract":"<p><p>Glomus tumours are painful superficial tumours, and ultrasonography is an extremely useful and noninvasive diagnostic technique for superficial organs. In this study, we retrospectively examined glomus tumours using ultrasonography. Among 18 patients histopathologically diagnosed with glomus tumours via ultrasonography, we observed five different development sites: subungual areas or those surrounding the nail bed (12), other areas on the finger surface (3), abdominal wall (1), upper arm (1), and forearm (1). The ultrasonographic images revealed significant differences in tumour size, indicating that tumours on other body surfaces tended to be smaller than those on patients' fingers (<i>p</i> < 0.01). The depth/width ratios of tumours on the other body surfaces were significantly higher than those on the fingers (<i>p</i> < 0.05). The tumours showed a regular shape (72.2%) and clear border (100%). Furthermore, most tumours were low-echo tumours with a diameter of up to 15 mm, clear margins, and no lateral shadows. Abundant blood flow and vessels in and out of the tumours were also observed. In conclusion, our study describes the ultrasonographic characteristics of glomus tumours and reveals that they cannot be ruled out when diagnosing small painful subcutaneous tumours.</p>","PeriodicalId":11338,"journal":{"name":"Dermatology Research and Practice","volume":"2023 ","pages":"7126799"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10397493/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10308778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}