Drug and alcohol dependence最新文献

{"title":"The System Isn’t Broken; How do we fix it? The Need for Workplace Education About Harm Reduction","authors":"Nithya Narayanan * , Miryam Baied , Debbie Humphries , Katie Wang , Phillip Marotta , Robert Heimer","doi":"10.1016/j.drugalcdep.2024.111509","DOIUrl":"10.1016/j.drugalcdep.2024.111509","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111509"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Cannabis Use Frequency and Total Body Water Among Young Black Adults","authors":"Larry Keen *","doi":"10.1016/j.drugalcdep.2024.111459","DOIUrl":"10.1016/j.drugalcdep.2024.111459","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111459"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143092508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interprofessional Perspectives on Caring for Hospitalized Patients With Opioid Use Disorder","authors":"Margaret Lowenstein * , M Holliday-Davis , Lilah Lesniak , David Mandell , Judy Shea","doi":"10.1016/j.drugalcdep.2024.111517","DOIUrl":"10.1016/j.drugalcdep.2024.111517","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111517"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Informing the Development of Interventions for E-Cigarette Use and Smoking Risk in Young Adults","authors":"Denise Tran * , Jordan Davis , Colin Ring , Keegan Buch , Eric Pedersen","doi":"10.1016/j.drugalcdep.2024.111483","DOIUrl":"10.1016/j.drugalcdep.2024.111483","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111483"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143105247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Intravenous vs Subcutaneous Administration of the Monoclonal Antibody, CSX-1004 That Blocks Fentanyl’s Effects in Squirrel Monkeys","authors":"Rajeev Desai * , Brissa Black , Emily Burke , Paul Bremer","doi":"10.1016/j.drugalcdep.2024.111504","DOIUrl":"10.1016/j.drugalcdep.2024.111504","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111504"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143132144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioral Economic Interactions Between Cannabis and Delta-8","authors":"Maribel Rodriguez Perez * , Shahar Almog , Meredith Berry","doi":"10.1016/j.drugalcdep.2024.111441","DOIUrl":"10.1016/j.drugalcdep.2024.111441","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111441"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cannabis Use and Cannabis Use Disorder by Psychiatric Disorders: 2001-2002 and 2012-2013","authors":"Julia Bujno * , Caroline Wisell , Malki Stohl , Deborah Hasin","doi":"10.1016/j.drugalcdep.2024.111454","DOIUrl":"10.1016/j.drugalcdep.2024.111454","url":null,"abstract":"","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 111454"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143164884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tobacco cessation, mental health, and substance use in a community pharmacist-linked cessation program for people experiencing homelessness","authors":"Kaitlyn Kui ,&nbsp;Christian Hailozian ,&nbsp;Mable Thai ,&nbsp;Deepalika Chakravarty ,&nbsp;Dorie E. Apollonio ,&nbsp;Lisa Kroon ,&nbsp;Maya Vijayaraghavan","doi":"10.1016/j.drugalcdep.2024.112527","DOIUrl":"10.1016/j.drugalcdep.2024.112527","url":null,"abstract":"<div><h3>Introduction</h3><div>The prevalence of tobacco use among people experiencing homelessness is 70 %. Mental health and substance use disorders are associated with tobacco use and pose challenges for tobacco cessation.</div></div><div><h3>Methods</h3><div>Between 2019 and 2024, we recruited 206 adults experiencing homelessness from three homeless shelters in San Francisco, California. Participants were enrolled in a 12-week pharmacist-linked smoking cessation program that involved pharmacist counseling and furnishing of nicotine replacement therapy (NRT) and brief cessation coaching by trained shelter staff. We examined the association of provision of tobacco cessation interventions with two outcomes—weekly cigarette consumption and quit attempts—using mixed effects Poisson and logistic regression models respectively. We ran separate models with baseline mental health conditions and substance use disorders and adjusted for age, gender, race-ethnicity, time to first cigarette after waking, and baseline cigarette consumption in all models.</div></div><div><h3>Results</h3><div>Adjusting for baseline mental health conditions and other covariates, the use of pharmacist-furnished NRT was associated with lower weekly consumption (Incidence Rate Ratio [IRR]: 0.74, 95 % Confidence Interval [CI]: 0.71–0.76) and increased weekly quit attempts (Adjusted Odds Ratio (AOR): 1.78, 95 % CI: 1.23–2.58). After adjusting for baseline substances used and other covariates, use of pharmacist-furnished NRT was associated with lower weekly consumption (IRR: 0.74, 95 % CI: 0.73–0.76) and increased weekly quit attempts (AOR: 1.99, 95 % CI: 1.45–2.74).</div></div><div><h3>Conclusions</h3><div>A community pharmacist-linked cessation program in homeless shelters was associated with reduced consumption and increased weekly quit attempts, highlighting its potential for scalability among people experiencing homelessness with high rates of co-occurring behavioral health conditions.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 112527"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the first try: How many quit attempts are necessary to achieve substance use cessation?","authors":"Rafaela M. Fontes ,&nbsp;Allison N. Tegge ,&nbsp;Roberta Freitas-Lemos ,&nbsp;Daniel Cabral ,&nbsp;Warren K. Bickel","doi":"10.1016/j.drugalcdep.2024.112525","DOIUrl":"10.1016/j.drugalcdep.2024.112525","url":null,"abstract":"&lt;div&gt;&lt;div&gt;Substance use disorder (SUD) is a chronically relapsing disorder; thus, individuals with SUD may require several attempts before achieving abstinence. The goal of the present study was to investigate what variables are associated with the number of quit attempts before successful abstinence was achieved. Data were collected from 421 International Quit &amp; Recovery Registry participants. Participants answered several questions for each substance they reported being in recovery, including how many times they had attempted to quit that substance and whether they still used that substance. The results showed that the number of quit attempts was associated with the substance one was trying to quit, SUD severity (i.e., mild, moderate, severe SUD) for that substance, the number of years using that substance, and the age of use onset. Pairwise comparisons among substances indicated that pain medication and opioids had a significantly higher number of quit attempts than all other substances (&lt;em&gt;p&lt;/em&gt;s &lt; .001) but were not different from each other (&lt;em&gt;p&lt;/em&gt; = 1.0). Pairwise comparisons across levels of SUD severity showed a significantly higher number of attempts for those with moderate than mild SUD (&lt;em&gt;p&lt;/em&gt; &lt; .001) and for those with severe than mild or moderate SUD (&lt;em&gt;p&lt;/em&gt;s &lt; .001). Overall, the results indicate that individuals who use opioids and pain medication, have more severe SUD, and more years of use need significantly more attempts before achieving successful abstinence. Thus, those might benefit from more targeted and effective interventions.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Background and aims&lt;/h3&gt;&lt;div&gt;Substance use disorder (SUD) is a chronically relapsing disorder. Thus, individuals with SUD may need several attempts before achieving abstinence. The present study investigated the variables associated with the number of quit attempts before achieving successful abstinence.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;Data were collected from 421 International Quit &amp; Recovery Registry participants. Participants answered several questions for each substance they reported being in recovery from, such as the age of first use, how many times they had attempted to quit that substance, and whether they still used that substance.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The number of quit attempts was associated with the substance one was trying to quit, SUD severity (i.e., mild, moderate, severe SUD) for that substance, the number of years using that substance, and the age of use onset. Pairwise comparisons among substances indicated that pain medication and opioids had a significantly higher number of quit attempts than all other substances (&lt;em&gt;p&lt;/em&gt;s &lt; .001) but were not different from each other (&lt;em&gt;p&lt;/em&gt; = 1.0). Pairwise comparisons across levels of SUD severity showed a significantly higher number of attempts for those with moderate than mild SUD (&lt;em&gt;p&lt;/em&gt; &lt; .001) and for those with severe than mild or moderate SUD (&lt;em","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 112525"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opioid use disorder prevalence in 57 New York counties from 2017 to 2019: A Bayesian evidence synthesis","authors":"Tian Zheng ,&nbsp;Katherine Keyes ,&nbsp;Shouxuan Ji ,&nbsp;Anna Calderon ,&nbsp;Elwin Wu ,&nbsp;Nathan J. Doogan ,&nbsp;Jennifer Villani ,&nbsp;Redonna Chandler ,&nbsp;Joshua A. Barocas ,&nbsp;Trang Nguyen ,&nbsp;Nabila El-Bassel ,&nbsp;Daniel J. Feaster","doi":"10.1016/j.drugalcdep.2025.112548","DOIUrl":"10.1016/j.drugalcdep.2025.112548","url":null,"abstract":"<div><h3>Introduction</h3><div>Prevalence estimates of opioid use disorder (OUD) at local levels are critical for public health planning and surveillance, yet largely unavailable across the US especially at the local county level.</div></div><div><h3>Methods</h3><div>We used a Bayesian evidence synthesis approach to estimate the prevalence of OUD for 57 counties across New York State for 2017–2019 and compare rates of OUD across counties as well as assess the extent of undiagnosed OUD. We developed a generative model to assess conditional probabilistic relations between different subgroups of the OUD population defined by diagnosis, treatment, and overdose fatality.</div></div><div><h3>Results</h3><div>Average OUD prevalence from 2017 to 2019 ranged from 2.4 % (Westchester County) to 8.3 % (Sullivan County). Overall OUD prevalence estimates were relatively stable year to year, from 4.5 % in 2018 and 4.6 % in both 2017 and 2019. The Bayesian evidence synthesis estimate is consistently higher than the percentage diagnosed in Medicaid, by age and sex. By 2019, the estimated proportion of OUD that was undiagnosed ranged from 16.7 % in Clinton County to 62.7 % in Onondaga County. Counties with relatively high overdose death rates and low buprenorphine prescription percentages had the highest estimated level of undiagnosed OUD.</div></div><div><h3>Conclusion</h3><div>OUD prevalence varied considerably across the state. We identified counties with high OUD and overdose levels and a high proportion of undiagnosed OUD, providing insight into areas of the state in need of rapid expansion of services for people with OUD. Bayesian evidence synthesis approaches for OUD prevalence estimation represent a reliable and rigorous approach to providing local areas with information on OUD magnitude.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"267 ","pages":"Article 112548"},"PeriodicalIF":3.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}