{"title":"Affective reinforcement of simultaneous versus single use of alcohol and cannabis","authors":"Andrea M. Wycoff , Timothy J. Trull","doi":"10.1016/j.drugalcdep.2025.112612","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Simultaneous alcohol and cannabis use is prevalent among adults who drink alcohol and is associated with more negative consequences than use of either substance alone. Understanding reinforcement processes that maintain simultaneous versus single-substance use will highlight intervention targets specific to this pattern of use. In individuals’ daily lives, we tested whether simultaneous use moments are associated with more affectively reinforcing outcomes compared to single use moments.</div></div><div><h3>Methods</h3><div>We used ecological momentary assessment with 6 + daily reports for 14 days. Participants were 88 adults ages 18–44 who reported simultaneous use at least twice per week. Mean age was 25.22 years and participants were 60.2 % female. At each momentary survey, participants reported alcohol and cannabis use, affect, momentary coping and enhancement motives, and subjective appraisals of use.</div></div><div><h3>Results</h3><div>Simultaneously using cannabis during alcohol-use moments attenuated the <em>increase</em> in negative affect that accompanied coping-motivated drinking (anxious mood <em>b</em> = −0.11, <em>95 % CI</em> = [-0.19, −0.02], <em>p</em> = .016; depressed mood <em>b</em> = −0.14, <em>95 % CI</em> = [-0.23, −0.05], <em>p</em> = .003). Simultaneously using cannabis during alcohol-use moments attenuated the positive association between enhancement drinking motives and subjective drinking-contingent pleasure (<em>b</em> = −0.34, <em>95 % CI</em> = [-0.50, −0.18], <em>p</em> < .001).</div></div><div><h3>Conclusions</h3><div>Simultaneously using cannabis during alcohol-use moments altered the subjective effects of alcohol, whereas simultaneously consuming alcohol during cannabis-use moments did not alter the subjective effects of cannabis. Individuals may perceive that simultaneous cannabis use mitigates undesirable effects of coping-motivated drinking, thereby driving simultaneous use of cannabis alongside alcohol.</div></div>","PeriodicalId":11322,"journal":{"name":"Drug and alcohol dependence","volume":"270 ","pages":"Article 112612"},"PeriodicalIF":3.9000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug and alcohol dependence","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0376871625000651","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0
Abstract
Background
Simultaneous alcohol and cannabis use is prevalent among adults who drink alcohol and is associated with more negative consequences than use of either substance alone. Understanding reinforcement processes that maintain simultaneous versus single-substance use will highlight intervention targets specific to this pattern of use. In individuals’ daily lives, we tested whether simultaneous use moments are associated with more affectively reinforcing outcomes compared to single use moments.
Methods
We used ecological momentary assessment with 6 + daily reports for 14 days. Participants were 88 adults ages 18–44 who reported simultaneous use at least twice per week. Mean age was 25.22 years and participants were 60.2 % female. At each momentary survey, participants reported alcohol and cannabis use, affect, momentary coping and enhancement motives, and subjective appraisals of use.
Results
Simultaneously using cannabis during alcohol-use moments attenuated the increase in negative affect that accompanied coping-motivated drinking (anxious mood b = −0.11, 95 % CI = [-0.19, −0.02], p = .016; depressed mood b = −0.14, 95 % CI = [-0.23, −0.05], p = .003). Simultaneously using cannabis during alcohol-use moments attenuated the positive association between enhancement drinking motives and subjective drinking-contingent pleasure (b = −0.34, 95 % CI = [-0.50, −0.18], p < .001).
Conclusions
Simultaneously using cannabis during alcohol-use moments altered the subjective effects of alcohol, whereas simultaneously consuming alcohol during cannabis-use moments did not alter the subjective effects of cannabis. Individuals may perceive that simultaneous cannabis use mitigates undesirable effects of coping-motivated drinking, thereby driving simultaneous use of cannabis alongside alcohol.
期刊介绍:
Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.