Interventions targeting adolescent substance use and misuse in South Asian Countries: A systematic review

IF 3.9 2区医学 Q1 PSYCHIATRY

Drug and alcohol dependence Pub Date : 2025-02-17 DOI:10.1016/j.drugalcdep.2025.112614

Rabia Hanif , Wendy Kliewer , John W. Cyrus

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引用次数: 0

Abstract

Background

This systematic review synthesizes evidence from 10 intervention studies focused on substance use interventions for adolescents across eight South Asian countries.

Methods

A literature search was conducted across MEDLINE (Ovid), Embase (Ovid), PsycINFO (EBSCO), Global Index Medicus, Web of Science (Clarivate), and Global Health (CAB Direct), covering studies from database October 1, 2016 to May 28, 2024. Only randomized control trials and quasi-experimental designs were included. The search strategy was pre-registered on the Open Science Framework.

Results

Out of 6356 studies identified, 4494 were screened, 193 were assessed for eligibility, and 10 studies were included in the review after consensus by two independent reviewers. Across these studies, which included 16,241 participants aged 9–18, seven were universal interventions, while three were targeted toward adolescents who were already using substances. Interventions primarily were conducted in school settings (n = 8) with a focus on tobacco, alcohol, inhalants, and supari use. Most studies demonstrated low selection and reporting bias, though performance and detection bias were unclear due to blinding limitations. Intervention duration ranged from 2 to 24 weeks and included between 2 and 119 sessions. Effectiveness was noted in four studies, three had mixed outcomes, two reported no significant effects, and one showed effects opposite of predicted outcomes.

Conclusion

This review reveals varied intervention outcomes on adolescent substance use in South Asia, with positive effects in a subset of studies. These findings highlight the need for additional interventions with strong methodological rigor to reduce adolescent substance use and misuse in this region.

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方法在MEDLINE（Ovid）、Embase（Ovid）、PsycINFO（EBSCO）、Global Index Medicus、Web of Science（Clarivate）和Global Health（CAB Direct）等数据库中进行文献检索，涵盖2016年10月1日至2024年5月28日期间的研究。仅纳入随机对照试验和准实验设计。检索策略在开放科学框架上进行了预先注册。结果在确定的 6356 项研究中，筛选出 4494 项研究，对 193 项研究进行了资格评估，经两位独立审稿人协商一致后，将 10 项研究纳入了综述。这些研究共纳入了 16241 名年龄在 9-18 岁的参与者，其中 7 项研究为普遍干预，3 项研究针对已经使用药物的青少年。干预措施主要在学校环境中进行（n = 8），重点关注烟草、酒精、吸入剂和 supari 的使用。大多数研究的选择偏差和报告偏差较低，但由于盲法的限制，效果偏差和检测偏差尚不明确。干预持续时间从 2 周到 24 周不等，包括 2 到 119 个疗程。四项研究显示干预有效，三项研究结果不一，两项研究报告无显著效果，一项研究显示的效果与预测结果相反。这些研究结果突出表明，有必要采取更多方法严谨的干预措施，以减少该地区青少年的药物使用和滥用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Drug and alcohol dependence 医学-精神病学

CiteScore

7.40

自引率

7.10%

发文量

409

审稿时长

41 days

期刊介绍： Drug and Alcohol Dependence is an international journal devoted to publishing original research, scholarly reviews, commentaries, and policy analyses in the area of drug, alcohol and tobacco use and dependence. Articles range from studies of the chemistry of substances of abuse, their actions at molecular and cellular sites, in vitro and in vivo investigations of their biochemical, pharmacological and behavioural actions, laboratory-based and clinical research in humans, substance abuse treatment and prevention research, and studies employing methods from epidemiology, sociology, and economics.