Diseases of the Colon & Rectum最新文献

{"title":"Single-Port Robot Assisted Hartmann's Type End Ileostomy Reversal Using the Existing Ostomy Site.","authors":"Pavel Mazirka, Brittany Fenner, Krista P Terracina, Lindsey E Goldstein, Thomas E Read, Johan Nordenstam","doi":"10.1097/DCR.0000000000003648","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003648","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Program Directors for Colon and Rectal Surgery: First Four Decades.","authors":"Scott R Kelley","doi":"10.1097/DCR.0000000000003260","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003260","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Predictive Model for Colorectal Cancer Using Exhaled Volatile Organic Compounds.","authors":"Se-Jin Baek, Hosub Lim, Selim Oh, Seohee Lee, Yanghee Kim, Ji Eun Song, Jung Myun Kwak, Jin Kim, Seon-Hahn Kim, Dong Geun Sul","doi":"10.1097/DCR.0000000000003706","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003706","url":null,"abstract":"<p><strong>Background: </strong>Colorectal cancer is lacking non-invasive and efficient diagnostic markers. Recently, volatile organic compounds present in exhaled breath have emerged as potential diagnostic indicators for various diseases.</p><p><strong>Objective: </strong>This study aimed to establish a predictive model including exhaled volatile organic compounds for the diagnosis of colorectal cancer.</p><p><strong>Design: </strong>Prospective comparative study.</p><p><strong>Settings: </strong>Single academic medical center.</p><p><strong>Patients: </strong>Exhaled breath was collected prospectively from 112 colorectal cancer patients and 51 healthy controls. The exhaled breath of the research participants was collected under the control of various conditions, such as eating or smoking prior to collection.</p><p><strong>Interventions: </strong>A total of 53 volatile organic compounds was analyzed in exhaled breath using thermal desorption-gas chromatography/mass spectrometry.</p><p><strong>Main outcome measures: </strong>After correcting various clinical variables that may affect volatile organic compound, the concentrations detected in the colorectal cancer group and the healthy control group were compared.</p><p><strong>Results: </strong>Four predictive models were established using both matched clinical variables and volatile organic compound values to differentiate between colorectal cancer and healthy controls. In the four models, clinical variables of age, gender, room temperature, heating and cooling, fasting duration, intake of grilled meat or fish, and bowel preparation were included, along with levels of eight volatile organic compounds (ethanol, decanal, 1-iodononane, dodecane, hexanal, 1-nonene, (1S)-(-)-alpha-pinene, and acetophenone). The sensitivity of the four prediction models ranged from 84.0% to 98.2%, the specificity ranged from 89.2% to 93.8%, and the area under the receiver operating characteristic curve ranged from 92.1% to 98.3%.</p><p><strong>Limitations: </strong>The demographics of the participants in the groups were different.</p><p><strong>Conclusions: </strong>Eight types of volatile organic compounds in the exhaled breath of the colorectal cancer group were significantly different from those of the healthy control group. Our results support the diagnosis of colorectal cancer using a predictive model combining volatile organic compounds and specific clinical variables. See Video Abstract.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Commentary on Diagnosis and Management of Common Stomal Complications.","authors":"Jennifer S Davids","doi":"10.1097/DCR.0000000000003717","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003717","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Appraising a CREATEive Surgeon-Scientist Initiative: Impact and Future Directions.","authors":"Christopher J Neylan, Aron Bercz, Scott E Regenbogen, Emina Huang, J Joshua Smith, Lillias H Maguire, Jonathan B Mitchem","doi":"10.1097/DCR.0000000000003614","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003614","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approaches to Surgical Management of Anorectal Melanoma in the Pre- and Post-Immunotherapy Eras.","authors":"James A Pasch, Wendy Liu, Shahrir Kabir, Thomas Pennington","doi":"10.1097/DCR.0000000000003690","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003690","url":null,"abstract":"<p><strong>Background: </strong>Whilst revolutionary in cutaneous melanoma, immune checkpoint inhibitors have shown reduced efficacy in anorectal melanoma. Nevertheless, their emergence, and the possibility of improved outcomes, may have changed the surgical management paradigm.</p><p><strong>Objective: </strong>To review the surgical management of anorectal melanoma in pre- and post-immunotherapy eras.</p><p><strong>Design: </strong>A retrospective cohort study from the Melanoma Institute Australia Research Database.</p><p><strong>Settings: </strong>A quaternary melanoma referral center.</p><p><strong>Patients: </strong>Patients with anorectal melanoma from 1958 to 2021.</p><p><strong>Interventions: </strong>The use of abdominoperineal resection and wide local excision were compared in pre- and post-immunotherapy eras from first use in 2014.</p><p><strong>Main outcome measures: </strong>Type of surgery performed over time and overall survival.</p><p><strong>Results: </strong>A total of 56 patients were identified with anal (57.1%), anorectal (16.1%) and rectal melanoma (26.8%). Initial management was abdominoperineal resection (37.5%), low anterior resection (3.6%), wide local excision (46.4%) and non-surgical (12.5%) in metastatic or unresectable disease. Immunotherapy and targeted therapies were utilized in 21 patients (37.5%) from 2014 with no difference in mode of surgical management in pre- and post-immunotherapy eras (p = 0.134). Five-year survival was 12.5% for the entire cohort with no significant difference comparing patients receiving wide local excision or abdominoperineal resection (15.4% vs. 14.3%, log rank p = 0.77). Involved margins were significantly associated with wide local excision (15.4% vs. 4.8% p = 0.016) with similar rates of local recurrence (15.4% vs. 14.3% p = 0.58).</p><p><strong>Limitations: </strong>Anorectal melanoma is rare thus we present a small cohort managed across eight decades. Early checkpoint inhibitor trials excluded mucosal melanoma patients, limiting access in this cohort.</p><p><strong>Conclusions: </strong>Despite the introduction of immunotherapy, surgery remains pivotal in the management of anorectal melanoma. Surgical resection may be curative and prevent morbidity due to locoregional progression but can come at a cost of reduced quality of life. Centralized management in experienced centers should be encouraged for optimal multi-disciplinary management. See Video Abstract.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Anal Canal Mucosectomy: an Essential Step in Ileal Pouch Anastomosis.","authors":"Antonio Manenti, Stefania Caramaschi, Luca Reggiani Bonetti, Gianrocco Manco","doi":"10.1097/DCR.0000000000003713","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003713","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply.","authors":"Serena Perotti, Michela Mineccia, Paolo Massucco, Federica Gonella, A Ferrero","doi":"10.1097/DCR.0000000000003714","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003714","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial Intelligence Recognition System of Pelvic Autonomic Nerve During Total Mesorectal Excision.","authors":"Fanghai Han, Guangyu Zhong, Shilin Zhi, Naiqian Han, Yongjun Jiang, Jia'nan Tan, Lin Zhong, Shengning Zhou","doi":"10.1097/DCR.0000000000003547","DOIUrl":"10.1097/DCR.0000000000003547","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;The preservation of the pelvic autonomic nervous system in total mesorectal excision remains challenging to date. The application of laparoscopy has enabled visualization of fine anatomical structures; however, the rate of urogenital dysfunction remains high.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To establish an artificial intelligence neurorecognition system to perform neurorecognition during total mesorectal excision.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;This is a retrospective study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;The study was conducted at a single hospital.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Patients: &lt;/strong&gt;Intraoperative images or video screenshots of patients with rectal cancer admitted to the Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, between January 2016 and December 2023, were retrospectively collected.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measure: &lt;/strong&gt;Mean intersection over union, precision, recall, and F1 of the model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 1424 high-quality intraoperative images were included in the training group. The proposed model was obtained after 700 iterations. The mean intersection over union was 0.75, and it slowly increased with an increase in training time. The precision and recall of the nerve category were 0.7494 and 0.6587, respectively, and the F1 was 0.7011. The video prediction shows that the model achieves a high accuracy rate, which could facilitate effective neurorecognition.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitation: &lt;/strong&gt;This was a single-center study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The artificial intelligence model for real-time visual neurorecognition in total mesorectal excision was successfully established for the first time in China. Better identification of these autonomic nerves should allow for better preservation of urogenital function, but further research is needed to validate this claim. See Video Abstract .&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Sistema de reconocimiento con inteligencia artificial del nervio autnomo plvico durante la escisin total del mesorrectal: &lt;/strong&gt;ANTECEDENTES:La preservación del sistema nervioso autónomo pélvico en la escisión mesorrectal total sigue siendo un desafío hasta la fecha. La aplicación de la laparoscopia ha permitido la visualización de estructuras anatómicas finas; sin embargo, la tasa de disfunción urogenital sigue siendo alta.OBJETIVO:Establecer un sistema de reconocimiento neurológico con inteligencia artificial para realizar el reconocimiento neurológico durante la escisión mesorrectal total.DISEÑO Y ESCENARIO:Este estudio retrospectivo se realizó en un solo hospital.PACIENTES:Se recopilaron retrospectivamente imágenes intraoperatorias o capturas de pantalla de video de pacientes con cáncer de recto ingresados en el Departamento de Cirugía Gastrointestinal, del Hospital Memorial Sun Yat-sen, de la Universidad Sun Yat-sen, entre enero de 2016 y diciembre de 2023.PRINCIPALES MEDIDAS DE VALORACIÓN:Intersección media so","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"308-315"},"PeriodicalIF":3.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11837963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Low Anterior Resection With En Bloc Total Abdominal Hysterectomy With Bilateral Salpingo-oophorectomy.","authors":"Ankit Sharma, Yogesh Bansod, Avanish Saklani","doi":"10.1097/DCR.0000000000003396","DOIUrl":"10.1097/DCR.0000000000003396","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e103"},"PeriodicalIF":3.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}