Diseases of the Colon & Rectum最新文献

{"title":"Watch-and-Wait for Rectal Cancer: Insights from American Society of Colon and Rectal Surgeons Members.","authors":"Racquel S Gaetani, Tara Russell, Kera Kwan, Keren Ladin, Jonathan Abelson","doi":"10.1097/DCR.0000000000003862","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003862","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heineke-Mikulicz Strictureplasty of the Pouch Inlet.","authors":"Jeongyoon Moon, Olga Lavryk, Taha Qazi, Stefan D Holubar","doi":"10.1097/DCR.0000000000003764","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003764","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144590681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nodal Downstaging in Rectal Cancer Patients: Survival is Promising if YpN0 is Achieved.","authors":"Haigui Wan, Jingrong Weng, Jinlin Cai, Zhenghua Chen, Peisi Li, Junyi Han, Ziming Li, Zixiao Wan, Ze Yuan, Yingguo Gan, Mingzhe Huang, Xuan Li, Tuoyang Li, Xiaoxia Liu, Xiaolin Wang, Huichuan Yu, Binbin Liu, Jinxin Lin, Yanxin Luo","doi":"10.1097/DCR.0000000000003846","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003846","url":null,"abstract":"<p><strong>Background: </strong>Locally advanced rectal cancer is a critical health concern, with neoadjuvant therapy emerging as a pivotal strategy to enhance survival rates.</p><p><strong>Objective: </strong>This study aims to evaluate the prognostic value of achieving ypN0 status following neoadjuvant therapy patients with locally advanced rectal cancer, comparing survival outcomes among natural N0, downstaged N0, and ypN + groups.</p><p><strong>Design: </strong>We conducted a post hoc analysis of the FOWARC trial, employing Kaplan-Meier survival analysis and Cox regression models to assess overall survival, disease-free survival, and locoregional recurrence-free survival.</p><p><strong>Settings: </strong>The multicenter, randomized phase III FOWARC trial was conducted across 15 hospitals in China, adhering to ethical standards.</p><p><strong>Patients: </strong>Our cohort included 449 patients with locally advanced rectal cancer who underwent neoadjuvant chemoradiotherapy followed by total mesorectal excision.</p><p><strong>Interventions: </strong>Neoadjuvant chemoradiotherapy followed by total mesorectal excision.</p><p><strong>Main outcome measures: </strong>The primary endpoint was 5-year overall survival, with secondary endpoints being 3-year disease-free survival and 3-year locoregional recurrence-free survival.</p><p><strong>Results: </strong>The 5-year overall survival for natural N0 and downstaged N0 groups were 88% and 89%, respectively, significantly higher than the 73% observed in the ypN+ group (p = 0.0034). The complete pathological response rate was markedly lower in the ypN+ group. Multivariable analysis showed the ypN stage as an independent prognostic factor for overall survival.</p><p><strong>Limitations: </strong>The study's retrospective design may introduce potential biases in patient selection and preoperative staging.</p><p><strong>Conclusions: </strong>Achieving ypN0 status via neoadjuvant chemoradiotherapy significantly improves survival in patients with locally advanced rectal cancer, regardless of ypT or cN status. This status not only serves as an independent prognostic factor, but may also help to guide hypothesis-driven, individualized postoperative-treatment strategies. See Video Abstract.ClinicalTrials.gov identifier: NCT01211210.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on Standardizing the Definition of Each Colon Cancer Segment: Delphi Consensus on Clinical Decision-Making for Oncologic Outcomes.","authors":"Bingxu Liu, Hui Yang","doi":"10.1097/DCR.0000000000003877","DOIUrl":"10.1097/DCR.0000000000003877","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic Single-Port Trans-Stomal Proctectomy and Ileal-Pouch Anal Anastomosis Construction With Exoscope-Assisted Transanal Transection and Single-Stapled Anastomosis for Ulcerative Colitis.","authors":"Antonino Spinelli, Carlotta La Raja, Matteo Sacchi, Caterina Foppa","doi":"10.1097/DCR.0000000000003874","DOIUrl":"10.1097/DCR.0000000000003874","url":null,"abstract":"<p><strong>Background: </strong>Proctectomy with ileal pouch-anal anastomosis is a promising indication for the single-port approach, as the procedure can be performed using a single-port platform placed at the stoma site. A single-port robotic platform may address many of the challenges associated with single-incision laparoscopy. However, it lacks compatible stapling devices. Consequently, performing the distal rectal transection with linear laparoscopic staplers is suboptimal, as it often requires significant enlargement of the abdominal defect at the stoma site. The transanal transection and single-stapled anastomosis technique offers a practical solution, compensating for the absence of staplers while potentially providing additional benefits.</p><p><strong>Impact of innovation: </strong>Integrating the single-port robotic platform with the transanal transection and single-stapled anastomosis technique may provide technical advantages for restorative rectal surgery through a minimally invasive, single-incision approach. This strategy eliminates the need for fascial enlargement, additional ports and staplers, potentially lowering procedural costs. The use of an exoscope enhances the visualization of the transanal phase and improves the potential for learning.</p><p><strong>Technology materials and methods: </strong>A fully robotic single-port mesenteric lengthening and proctectomy were performed. The pouch was constructed through the stoma site, and the specimen retrieved transanally. An exoscope-assisted transanal transection and single-stapled anastomosis ileal pouch-anal anastomosis was performed.</p><p><strong>Preliminary results: </strong>The video shows the technique in a 26-year-old male patient with ulcerative colitis. The operation was completed without additional ports placement. No intraoperative or postoperative complications occurred. The patient was discharged on postoperative day 4. The ileostomy was reversed after six weeks.</p><p><strong>Conclusions and future directions: </strong>The fully robotic SP technique is feasible and safe in selected cases, particularly in centers with specialized expertise in ileal pouch-anal anastomosis surgery and robotic procedures. Its broader implementation will be further supported by the integration of advanced devices into the SP platform.</p>","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter.","authors":"Mehmet Ayhan Kuzu, Cigdem Benlice, Liliana G Bordeianou","doi":"10.1097/DCR.0000000000003876","DOIUrl":"https://doi.org/10.1097/DCR.0000000000003876","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Rectal Cuff Can Worsen the Results of an IPAA.","authors":"Antonio Manenti, Stefania Caramaschi, Luca Reggiani Bonetti, Gianrocco Manco","doi":"10.1097/DCR.0000000000003756","DOIUrl":"10.1097/DCR.0000000000003756","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"e1086"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardizing the Definition of Each Colon Cancer Segment: Delphi Consensus on Clinical Decision-Making for Oncologic Outcomes.","authors":"Mehmet Ayhan Kuzu, Cigdem Benlice, Amjad Parvaiz, Emre Gorgun, Claus A Bertelsen, Steven Wexner, Eric J Dozois, Werner Hohenberger, Danilo Miskovic, Konichi Sugihara, Antonino Spinelli, Theo Wiggers, Woo Yong Lee, Gabriela Möslein, Petr Tsarkov, Eloy Espin Basany, Juan Carlos Patron Uriburu, Rodrigo Olivia Perez, Craig Lynch, Zheng Liu, Dieter Hahnloser, Per J Nilsson, Nisar Ahmad Chowdri, Gina Brown, Philippe Rouanet, Robert D Madoff, Nick P West, Turgut Sahin, Atilla Halil Elhan, Liliana G Bordeianou","doi":"10.1097/DCR.0000000000003739","DOIUrl":"10.1097/DCR.0000000000003739","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Data registries lack a definitive classification system that distinguishes different locations of colon cancer from one another.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To establish an international consensus on the definition of primary colon cancer segment locations.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;Between December 2022 and June 2023, the Delphi survey study was conducted to seek opinions from relevant international experts and eventually develop a consensus definition of each colon cancer segment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Three-round online-based Delphi survey study.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Interventions: &lt;/strong&gt;The online survey included 17 questions. In the first 2 rounds, participating experts were asked to rank each statement on a scale of 1 (least relevant) to 9 (most relevant). Consensus statements and definitions were revised according to the results for statements obtaining a consensus score of 7 to 9. During the third round and online meeting, definitions and statements that reached a moderate or high consensus (above 4 for more than 70% of participants) were included.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome measures: &lt;/strong&gt;The primary goal of our project was focused on precisely localizing the specific segment affected by primary colon cancer rather than identifying surgical treatment or type of resection needed for a particular segment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The first round included 331 experts; 301 (91%) completed the second round and 295 (98%) completed the final round. Experts strongly supported the use of a \"10-cm rule\" to describe colon cancer sites at the flexures and anatomical landmarks for other segments. Regarding the definition of rectosigmoid cancer, experts from United States and Europe reached a high consensus that the term rectosigmoid as a colon cancer location must be abolished in contrast to experts from Asia. The description of overlapping segments of cancers achieved a consensus of 64%.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Limitations: &lt;/strong&gt;Subjective decisions are based on individual expert clinical experience.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This Delphi survey, the first internationally conducted consensus study, achieved a remarkable level of consensus among a panel of global experts. Ambiguity still exists regarding overlapping lesions. See Video Abstract .&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Estandarizacin de la definicin de cada segmento de cncer de colon consenso delphi sobre la toma de decisiones clnicas para resultados oncolgicos: &lt;/strong&gt;ANTECEDENTES:Las bases de datos carecen de un sistema de clasificación definitivo que distinga las diferentes localizaciones del cáncer de colon.OBJETIVO:Establecer un consenso internacional sobre la definición de las localizaciones de los segmentos del cáncer de colon priamrio.DISEÑO:Entre diciembre de 2022 y junio de 2023, se realizó un estudio Delphi para recabar la opinión de expertos internacionales relevantes y, finalmente, desarrollar una definición consensuada de cada segme","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"835-844"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Declining Colorectal Cancer Operations After Neoadjuvant Therapy: Having the Difficult Conversations.","authors":"Bailey K Hilty Chu, Fergal J Fleming","doi":"10.1097/DCR.0000000000003783","DOIUrl":"10.1097/DCR.0000000000003783","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"810-813"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143802734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The History of the New Jersey Salvati-Rubin Colon and Rectal Surgery Residency (Rutgers Robert Wood Johnson Medical School).","authors":"Theodore E Eisenstat, Daniel L Feingold, Kelly M Tyler, Bertram T Chinn, Kirsten B Wilkins","doi":"10.1097/DCR.0000000000003736","DOIUrl":"10.1097/DCR.0000000000003736","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"803-809"},"PeriodicalIF":3.2,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}