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Drug Metabolism and Pharmacokinetics最新文献

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Phenotyping assay using genetically manipulated human IPS cell-derived hepatocyte- like cells 利用基因操纵的人IPS细胞衍生的肝细胞样细胞进行表型分析
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101102
Hiroyuki Mizuguchi
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引用次数: 0
Bioanlaysis, biotransformation and pharmacokinetics of antibody-drug conjugate 抗体-药物偶联物的生物分析、生物转化和药代动力学
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101074
Yuki Kishino
{"title":"Bioanlaysis, biotransformation and pharmacokinetics of antibody-drug conjugate","authors":"Yuki Kishino","doi":"10.1016/j.dmpk.2025.101074","DOIUrl":"10.1016/j.dmpk.2025.101074","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101074"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Botanical-drug interactions: Blazing the trail using translational tools 植物-药物相互作用：利用翻译工具开辟道路
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101116
Mary Paine
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引用次数: 0
Discovery, validation, and application of transporter endogenous biomarkers: A work of translation 转运体内源性生物标志物的发现、验证和应用：翻译工作
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101093
Hong Shen
{"title":"Discovery, validation, and application of transporter endogenous biomarkers: A work of translation","authors":"Hong Shen","doi":"10.1016/j.dmpk.2025.101093","DOIUrl":"10.1016/j.dmpk.2025.101093","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101093"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selection of liver models of hepatic drug clearance: Improvements and implications for ivive and PBPK modeling 肝脏药物清除模型的选择：活体和PBPK模型的改进和意义
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101148
K. Sandy Pang, Weijia Ivy Lu, Gerard Mulder
{"title":"Selection of liver models of hepatic drug clearance: Improvements and implications for ivive and PBPK modeling","authors":"K. Sandy Pang, Weijia Ivy Lu, Gerard Mulder","doi":"10.1016/j.dmpk.2025.101148","DOIUrl":"10.1016/j.dmpk.2025.101148","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101148"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal secretion is potentially an important clearance mechanism for highly plasma-bound and low metabolic clearance efflux substrates 肠道分泌可能是高血浆结合和低代谢清除外排底物的重要清除机制
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101149
Murali Subramanian, Deepak Ahire, Rakshit Tanna, Josh Yu, Kelly Wang, Wei Wang, Gillian Smith, Xingrong Liu
{"title":"Intestinal secretion is potentially an important clearance mechanism for highly plasma-bound and low metabolic clearance efflux substrates","authors":"Murali Subramanian, Deepak Ahire, Rakshit Tanna, Josh Yu, Kelly Wang, Wei Wang, Gillian Smith, Xingrong Liu","doi":"10.1016/j.dmpk.2025.101149","DOIUrl":"10.1016/j.dmpk.2025.101149","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101149"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of physiological factors suppressing colonic drug absorption using quantum imaging technology 利用量子成像技术鉴定抑制结肠药物吸收的生理因素
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101141
Yugo Yasugi , Maho Hirosaki , Kazuki Hotta , Yumi Kato , Yasuyuki Ueda , Mayumi Iwatake , Hiroshi Yukawa , Ikumi Tamai , Yoshiyuki Shirasaka
{"title":"Identification of physiological factors suppressing colonic drug absorption using quantum imaging technology","authors":"Yugo Yasugi , Maho Hirosaki , Kazuki Hotta , Yumi Kato , Yasuyuki Ueda , Mayumi Iwatake , Hiroshi Yukawa , Ikumi Tamai , Yoshiyuki Shirasaka","doi":"10.1016/j.dmpk.2025.101141","DOIUrl":"10.1016/j.dmpk.2025.101141","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101141"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitigating strategy for drug induced liver injury LED by reactive metabolites 反应性代谢物对药物性肝损伤的缓解策略
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101065
Sean Zhu
{"title":"Mitigating strategy for drug induced liver injury LED by reactive metabolites","authors":"Sean Zhu","doi":"10.1016/j.dmpk.2025.101065","DOIUrl":"10.1016/j.dmpk.2025.101065","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101065"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling cannabinoids-drug interactions in aging: Insights from PBPK modeling 揭示大麻素-药物在衰老中的相互作用：来自PBPK模型的见解
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/j.dmpk.2025.101110
Zhu Zhou
{"title":"Unraveling cannabinoids-drug interactions in aging: Insights from PBPK modeling","authors":"Zhu Zhou","doi":"10.1016/j.dmpk.2025.101110","DOIUrl":"10.1016/j.dmpk.2025.101110","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101110"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144194669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TOC TOC
IF 2.7 4区 医学
Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI: 10.1016/S1347-4367(25)00438-0
{"title":"TOC","authors":"","doi":"10.1016/S1347-4367(25)00438-0","DOIUrl":"10.1016/S1347-4367(25)00438-0","url":null,"abstract":"","PeriodicalId":11298,"journal":{"name":"Drug Metabolism and Pharmacokinetics","volume":"61 ","pages":"Article 101488"},"PeriodicalIF":2.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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