Doklady Akademii nauk最新文献_第10页

CHANGES OF THE MICROCIRCULATORY SKIN BED AND ORGANS ASSOCIATED WITH THE HORMONAL-BIOCHEMICAL BACKGROUND IN WISTAR RATS WHEN MODELING DIABETES MELLITUS 糖尿病模型时wistar大鼠微循环皮肤、床和器官的激素生化变化

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-101-108

E. I. Kalinovskaya, L. Archakova, T. Kuznetsova, E. L. Ryzhkovskaya, T. A. Mityukova, O. E. Poluliakh, A. A. Basalai, T. V. Balashevich

引用次数: 0

ORIGIN OF AN ELECTROMAGNETIC FIELD UNDER IONIZATION CONDITIONS OF EXPLOSION PRODUCTS 爆炸产物电离条件下电磁场的起源

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-115-119

A. F. Ilyushchenko, V. Ovchinnikov

引用次数: 1

ВЛИЯНИЕ ГИБРИДНОГО НАПОЛНЕНИЯ КОРОТКИМ СТЕКЛОВОЛОКНОМ И ТЕРМОРАСШИРЕННЫМ ГРАФИТОМ НА СТРУКТУРУ И СВОЙСТВА ПОЛИЭТИЛЕНТЕРЕФТАЛАТА 短玻璃纤维和热膨胀石墨混合作用

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-120-128

Владимир Васильевич Дубровский, В. Н. Адериха, Владимир Анатольевич Шаповалов, С. С. Песецкий

{"title":"ВЛИЯНИЕ ГИБРИДНОГО НАПОЛНЕНИЯ КОРОТКИМ СТЕКЛОВОЛОКНОМ И ТЕРМОРАСШИРЕННЫМ ГРАФИТОМ НА СТРУКТУРУ И СВОЙСТВА ПОЛИЭТИЛЕНТЕРЕФТАЛАТА","authors":"Владимир Васильевич Дубровский, В. Н. Адериха, Владимир Анатольевич Шаповалов, С. С. Песецкий","doi":"10.29235/1561-8323-2018-62-1-120-128","DOIUrl":"https://doi.org/10.29235/1561-8323-2018-62-1-120-128","url":null,"abstract":"The effect of short glass fibers (GFs) and thermally expanded graphite (TEG), added to polyethyleneterephtalate (PET), on mechanical, including dynamical mechanical, and rheological properties, as well as the structural features of the produced composites is studied. Compounding with the PET melt is realized by reactive extrusion using a co-rotating twin screw extruder-reactor with L / D = 40. Analyzed composites contained from 15 to 60 wt. % of GFs, and the TEG concentration was 0.5 and 3.0 wt. It is found that hybrid filling of PET results in a synergetic increase of the tensile modulus of the composites reaching the values more than 22 GPa, as well as that of the dynamic shear modulus in a wide temperature range. Adding TEG into PET/GF composites increases the degree of binder crystallinity. An effect of an anomalous decrease in the intrinsic viscosity of PET solutions and an increase in the melt flow index of the melt composites observed at higher GF concentrations is attributed to a deeper degradation of polymer.","PeriodicalId":11227,"journal":{"name":"Doklady Akademii nauk","volume":"27 1","pages":"120-128"},"PeriodicalIF":0.0,"publicationDate":"2018-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84754420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

ANTICANCEROGENIC ACTIVITY OF BRASSINOSTEROIDS IN LIVER TUMOR CELLS 油菜素内酯在肝肿瘤细胞中的抗癌活性

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-66-72

O. V. Panibrat, P. Shabunya, S. Fatykhava, V. Zhabinskii, P. A. Kiselev

引用次数: 3

CHERENKOV-TYPE STIMULATED EMISSION IN GRAPHENE-BASED SYSTEMS 石墨烯基系统中的切伦科夫型受激辐射

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-33-40

K. Batrakov, S. Maksimenko

引用次数: 0

RAMAN SPECTROSCOPY STUDY OF THE BONE TISSUE WITH COXARTHROSIS 关节关节病骨组织的拉曼光谱研究

Doklady Akademii nauk Pub Date : 2018-03-05 DOI: 10.29235/1561-8323-2018-62-1-24-32

I. Parkhomenko, L. Vlasukova, F. Komarov, A. S. Kamyshan, G. A. Uryev, A. Murzich, R. Nemkaeva

引用次数: 0

ГЕНЕТИЧЕСКИЙ ПОЛИМОРФИЗМ ВНУТРИКЛЕТОЧНЫХ СИГНАЛЬНЫХ ПУТЕЙ У ПАЦИЕНТОВ С НЕМЕЛКОКЛЕТОЧНЫМ РАКОМ ЛЕГКОГО 非小细胞肺癌患者的细胞内信号通路基因多态性

Doklady Akademii nauk Pub Date : 2018-03-04 DOI: 10.29235/1561-8323-2018-62-1-78-85

А. Н. Щаюк, Э. В. Крупнова, М. Н. Шепетько, Е. П. Михаленко, Н. В. Чеботарёва, С. Ю. Дедик, А. В. Кильчевский

{"title":"ГЕНЕТИЧЕСКИЙ ПОЛИМОРФИЗМ ВНУТРИКЛЕТОЧНЫХ СИГНАЛЬНЫХ ПУТЕЙ У ПАЦИЕНТОВ С НЕМЕЛКОКЛЕТОЧНЫМ РАКОМ ЛЕГКОГО","authors":"А. Н. Щаюк, Э. В. Крупнова, М. Н. Шепетько, Е. П. Михаленко, Н. В. Чеботарёва, С. Ю. Дедик, А. В. Кильчевский","doi":"10.29235/1561-8323-2018-62-1-78-85","DOIUrl":"https://doi.org/10.29235/1561-8323-2018-62-1-78-85","url":null,"abstract":"The key process in the pathogenesis of any malignant neoplasms, including non-small cell lung cancer (NSCLC), is the angiogenesis that is activated by two tyrosine kinase cascades (RAS/RAF/MAPK and PI3K/AKT/mTOR). The main genes controlling these pathways are EGFR, KRAS, PIK3CA and PTEN. The study analyzed the mutations in 18–21 exons of the EGFR gene, 2 exons of the KRAS gene, 9 and 20 exons of the PIK3CA gene and 7 exons of the PTEN gene in patients with NSCLC living in Belarus and their relationship with the clinical and morphological characteristics of the tumor. Our results revealed that mutations in the EGFR gene are significantly frequent more than 5 times in patients with non-small cell lung cancer than those in the control group. Classical mutations in the EGFR gene are found only in patients with lung adenocarcinoma, predominantly in women. Mutations of the KRAS gene are found only in men, and in patients with adenocarcinoma it is 3 times more likely than in patients with squamous cell lung carcinoma. There are no somatic mutations in the PIK3CA and PTEN genes in patients with NSCLC in this study.","PeriodicalId":11227,"journal":{"name":"Doklady Akademii nauk","volume":"53 1","pages":"78-85"},"PeriodicalIF":0.0,"publicationDate":"2018-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89096387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ОБ ОЦЕНКАХ ВЕЛИЧИН РЕЗУЛЬТАНТОВ ЦЕЛОЧИСЛЕННЫХ ПОЛИНОМОВ БЕЗ ОБЩИХ КОРНЕЙ

Doklady Akademii nauk Pub Date : 2018-03-04 DOI: 10.29235/1561-8323-2018-62-1-18-23

Алексей Сергеевич Кудин

{"title":"ОБ ОЦЕНКАХ ВЕЛИЧИН РЕЗУЛЬТАНТОВ ЦЕЛОЧИСЛЕННЫХ ПОЛИНОМОВ БЕЗ ОБЩИХ КОРНЕЙ","authors":"Алексей Сергеевич Кудин","doi":"10.29235/1561-8323-2018-62-1-18-23","DOIUrl":"https://doi.org/10.29235/1561-8323-2018-62-1-18-23","url":null,"abstract":"In the article we present an improvement to the lemma on the order of simultaneous zero approximation by the values of two integer polynomials without common roots from A. O. Gelfond’s monograph “Transcendental and algebraic numbers”. The lemma says that if two integer polynomials P1 and P2 of degree not exceeding n1 and n2 and of height not exceeding Qµ1 and Qµ2 respectively having no roots in common take values 1 Px Q 1( ) −τ < and 2 Px Q 2 ( ) −τ < at some transcendental point x ∈i, then min( , ) τ τ < µ + µ +δ 1 2 12 21 n n . Gelfond’s lemma and similar results have important applications to many problems of the metric theory of Diophantine approximation. One of such applications is the result due to V. Bernik (1983) on the upper bound for the Hausdorff dimension of the set of real numbers with specified order of zero approximation by the values of integer polynomials. This result along with the result of A. Baker and W. Schmidt (1970) on the lower bound of the Hausdorff dimension of the set mentioned above gives the exact formula. In order to prove the upper bound V. Bernik improved and extended Gelfond’s lemma by considering the values of polynomials of degree not exceeding n and of height not exceeding Qµ on some interval of length Q−η and obtaining a stronger inequality τ+µ+ τ+µ−η < µ +δ 2max( , 0) 2 , n τ= τ τ min( , ). 1 2 However, the need to consider the same estimates for the degree and height of the polynomials is still restrictive and limits the range of problems this result could be applied to. In our work we consider the values of polynomials of different degrees and heights on an interval and obtain a stronger estimate by using higher order derivatives, thus improving and extending Gelfond’s lemma and existing similar results. The result is obtained using the methods of the theory of transcendental numbers.","PeriodicalId":11227,"journal":{"name":"Doklady Akademii nauk","volume":"56 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2018-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84782279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКАЯ ИДЕНТИФИКАЦИЯ ИНВАЗИВНОГО ВИДА – ШАКАЛА АЗИАТСКОГО (CANIS AUREUS) НА ТЕРРИТОРИИ БЕЛАРУСИ 入侵物种的分子-基因鉴定-亚洲豺狼(CANIS AUREUS)在白俄罗斯境内

Doklady Akademii nauk Pub Date : 2018-03-04 DOI: 10.29235/1561-8323-2018-62-1-86-92

E. Kheidorova, A. Shpak, K. Homel, Vadim E. Sidorovich, Victar V. Demianchyk, Vadzim V. Prakapchuk, M. Nikiforov

{"title":"МОЛЕКУЛЯРНО-ГЕНЕТИЧЕСКАЯ ИДЕНТИФИКАЦИЯ ИНВАЗИВНОГО ВИДА – ШАКАЛА АЗИАТСКОГО (CANIS AUREUS) НА ТЕРРИТОРИИ БЕЛАРУСИ","authors":"E. Kheidorova, A. Shpak, K. Homel, Vadim E. Sidorovich, Victar V. Demianchyk, Vadzim V. Prakapchuk, M. Nikiforov","doi":"10.29235/1561-8323-2018-62-1-86-92","DOIUrl":"https://doi.org/10.29235/1561-8323-2018-62-1-86-92","url":null,"abstract":"An ordinary jackal (Canis aureus Linnaeus, 1758) is a mammal species of the Canidae family that has been characterized by a rapid expansion of the range in recent decades. In Belarus, the first report on the registration of the jackal appeared in 2012 and concerned an animal that was found in the southeast of the Brest region at the end of 2011. However, this finding was not scientifically confirmed at that time. The purpose of this work was to establish by means of molecular genetic methods the species affiliation of “jackal-like” individuals hunted at different times in the territory of Belarus. Molecular genetic studies conducted on the biomaterial of three animals with unclear species affiliation confirmed the fact of the first registration of the Asian jackal in the territory of Belarus in December 2011. It is given that an Asian jackal has a connection with the Balkan distribution center. The other two “jackal-like” individuals were the representatives of the species Canis lupus on the maternal line. However, it is possible that their morphological features unusual for wolves are a consequence of their hybridization with domestic dogs. This requires a further careful study based on the nuclear genome.","PeriodicalId":11227,"journal":{"name":"Doklady Akademii nauk","volume":"1 1","pages":"86-92"},"PeriodicalIF":0.0,"publicationDate":"2018-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83016773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

LIGAND-BINDING AND CATALYTIC PROPERTIES OF RECOMBINANT HUMAN THROMBOXANE SYNTHASE 重组人血栓素合成酶的配体结合及催化性能

Doklady Akademii nauk Pub Date : 2018-01-01 DOI: 10.29235/1561-8323-2018-62-1-51-65

A. V. Svirid, M. Shapira, Pavel G. Shahoika, Y. Pakhadnia, A. Gilep, S. Usanov

引用次数: 0