Designed Monomers and Polymers最新文献_第4页

The effect of inorganic salt on the morphology and nucleation of polyaniline nanofibers synthesized via self-assembly. 无机盐对自组装聚苯胺纳米纤维形态和成核的影响。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2166727

Ruijuan Wang, Yiqi Jing

{"title":"The effect of inorganic salt on the morphology and nucleation of polyaniline nanofibers synthesized via self-assembly.","authors":"Ruijuan Wang, Yiqi Jing","doi":"10.1080/15685551.2023.2166727","DOIUrl":"https://doi.org/10.1080/15685551.2023.2166727","url":null,"abstract":"Polyaniline (PANI), due to the various and controllable shapes, the environmental stability, the excellent physical and chemical property, has gained significant attention. PANI with abundant morphologies were successfully prepared through adjusting and controlling the state of the initial micelle-like in the micelle-like system composed by aniline and organic acids with relatively weak intermolecular interaction. Although the influence of the inorganic salts on their morphology, including the surface and the diameter, was investigated, the influence of salt on the nucleation of PANI was still unclear. Therefore, PANI nanofibers were fabricated through the addition of inorganic salt such as NaCl, MgSO4 and AlCl3 into the micelle-like composed of aniline and D-camphor-10-sulfonic acid. The influence of types and concentration of inorganic salts, doped acids and temperature on PANI was studied by Transmission Electron Microscope (TEM), UV-vis and Fourier Transform Infrared Spectroscopy (FTIR) spectroscopy. In addition, in situ UV-vis and 1H Nuclear Magnetic Resonance technology (NMR) were applied to observe the process of aniline polymerization, and it was indicated the polymerization rate of aniline changed after the addition of inorganic salt NaCl into the initial solution.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"45-53"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858426/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9132344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A spotlight on application of microwave-assisted modifications of plant derived polymers in designing novel drug delivery systems. 重点介绍了微波辅助修饰植物衍生聚合物在设计新型给药系统中的应用。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2194176

Girish Meravanige Basavarajappa, K M Priyanka, Prakash Goudanavar, Lakshmi G Narasimha, N Raghavendra Naveen, Buduru Gowthami, Santosh Fattepur, Predeepkumar Narayanappa Shiroorkar, Sreeharsha Nagaraja, Mallikarjun Telsang, Veeriah Chowdary Jasthi, Pavan Kumar Pavagada Sreenivasalu

{"title":"A spotlight on application of microwave-assisted modifications of plant derived polymers in designing novel drug delivery systems.","authors":"Girish Meravanige Basavarajappa, K M Priyanka, Prakash Goudanavar, Lakshmi G Narasimha, N Raghavendra Naveen, Buduru Gowthami, Santosh Fattepur, Predeepkumar Narayanappa Shiroorkar, Sreeharsha Nagaraja, Mallikarjun Telsang, Veeriah Chowdary Jasthi, Pavan Kumar Pavagada Sreenivasalu","doi":"10.1080/15685551.2023.2194176","DOIUrl":"https://doi.org/10.1080/15685551.2023.2194176","url":null,"abstract":"Polymers are a fundamental part of numerous industries and can be conjugated with many other materials and components to have a vast array of products. Biomaterials have been extensively studied for their application in pharmaceutical formulation development, tissue engineering, and biomedical areas. However, the native form of many polymers has limitations concerning microbial contamination, susceptibility, solubility, and stability. Chemical or physical modifications can overcome these limitations by tailoring the properties of polymers to meet several requirements. The polymer modifications are interdisciplinary, cutting across conventional materials, physics, biology, chemistry, medicine, and engineering limitations. Microwave irradiation has become a well-established technique for a few decades to drive and promote chemical modification reactions. This technique allows ease of temperature and power control to perform the synthesis protocols efficiently. Additionally, microwave irradiation contributes to green and sustainable chemistry. In this contribution, microwave-assisted polymer modifications were described with a special focus on their application in developing several novel dosage forms.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"106-116"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/1a/TDMP_26_2194176.PMC10064828.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9241826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation and physicochemical studies on polymeric nanocomposites containing copper oxide nanoparticles. 含氧化铜纳米聚合物复合材料的制备及物理化学研究。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2190222

Soad Alsheheri, Zahra Alamshany, Magdy Y Abdelaal

引用次数: 3

Facile fabrication of polystyrene particles/graphene composites for improved dielectric and thermal properties. 用于改善介电和热性能的聚苯乙烯颗粒/石墨烯复合材料的简易制备。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2022.2162282

Wei Deng, Guoan Li, Wanyu Li, Meng Yang, Weiwei Cui

引用次数: 4

Synthesis and characterization of novel thermoresponsive suspensions via physical adsorption of poly[di(ethylene glycol) methyl methacrylate] onto polystyrene microparticles. 聚苯乙烯微粒物理吸附聚二(乙二醇)甲基丙烯酸甲酯新型热响应悬浮液的合成与表征。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2211356

Azad Sadraddin

{"title":"Synthesis and characterization of novel thermoresponsive suspensions via physical adsorption of poly[di(ethylene glycol) methyl methacrylate] onto polystyrene microparticles.","authors":"Azad Sadraddin","doi":"10.1080/15685551.2023.2211356","DOIUrl":"https://doi.org/10.1080/15685551.2023.2211356","url":null,"abstract":"Thermoreversible colloidal suspensions/gels have attracted recent research attention in the field of biomedical applications. In this study, a novel thermoresponsive particle suspension with thermoreversible gelation properties has been prepared for biomedical application. First, polystyrene (PS) microspheres were synthesized by dispersion polymerization and poly diethyleneglycolmethylmethacrylate (PDEGMA) polymer were synthesized via free radical polymerisation. Then, the new developed thermoresponsive suspensions were prepared via physical adsorption of a thermoresponsive polymer, poly[di (ethylene glycol) methyl methacrylate] (PDEGMA), onto the surface of polystyrene microspheres. PDEGMA acts as a steric stabilizer and induces thermoreversible gelation via chain extending and collapsing below and above its lower critical solution temperature (LCST), respectively. Scanning electron microscopy (SEM), 1H NMR spectroscopy, Gel permeation chromatography (GPC), UV-vis spectroscopy, Rheometric measurement were conducted to characterize the prepared particles, polymers and suspensions. SEM images show that monodisperse microspheres with the sizes range 1.5-3.5 μm were prepared. UV-vis measurements demonstrate thermoresponsive properties of PDEGMA. 1H NMR and GPC analysis confirms structural properties of prepared PDEGMA. Tube inversion tests demonstrated that the aqueous suspensions of the particles and polymer exhibited thermoreversible fluid-to-gel transitions. Rheological characterization revealed that the viscoelastic properties of the prepared suspension/gels can be fine tuned. This enables applications of the prepared gels as scaffolds for three-dimensional (3D) cell cultures.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"163-170"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10192345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation and properties of silica sol/melamine glyoxal resin. 硅溶胶/三聚氰胺乙二醛树脂的制备及性能研究。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2022.2162280

Zexiu Qin, Yinliang Zhang, Mingli Liu, Chunfeng Li

{"title":"Preparation and properties of silica sol/melamine glyoxal resin.","authors":"Zexiu Qin, Yinliang Zhang, Mingli Liu, Chunfeng Li","doi":"10.1080/15685551.2022.2162280","DOIUrl":"https://doi.org/10.1080/15685551.2022.2162280","url":null,"abstract":"In this study, a composite modifier for wood impregnation is prepared, which is functional and environmentally friendly. The surface of silica sol was modified by using KH-560. The modified silica sol, melamine, and glyoxal were used as raw materials. The silica sol/melamine glyoxal resin (from now on referred to as Silica sol/MG) composite modifier was prepared based on in-situ polymerization. The physicochemical properties (viscosity, solid content and etc.) of the composite modifier were evaluated. The structural and thermal properties were characterized and analyzed by FTIR spectroscopy, particle size distribution, TG and DSC. The results showed that the viscosity and solid content of the composite modifier decreased with the increase in the mass of the silica sol. The FTIR spectroscopy showed peaks at 473 cm-1 and 1101 cm-1, which were assigned to bending and stretching vibrations of the Si-O-Si bond, respectively, indicating that the modified silica sol was successfully introduced into the MG resin. When the modified silica sol mass fraction was 30%-40%, the particle size distribution of the composite modifier was relatively uniform. TG analysis found that the thermal stability of the composite modifier was significantly improved compared with the unmodified resin. DSC analysis showed that adding the modified silica sol reduced the curing temperature of the modifier from 115.5 °C to 107.9 °C.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"15-22"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/e2/TDMP_26_2162280.PMC9809364.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10488600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Ethylene polymerization using N-Heterocyclic carbene complexes of silver and aluminum. 银和铝的n -杂环羰基配合物的乙烯聚合。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2229641

Nanako Kimura, Daisuke Takeuchi, Sayoko Ogura, Ayaka Takazawa, Masaki Kakiage, Takeshi Yamanobe, Hiroki Uehara

{"title":"Ethylene polymerization using N-Heterocyclic carbene complexes of silver and aluminum.","authors":"Nanako Kimura, Daisuke Takeuchi, Sayoko Ogura, Ayaka Takazawa, Masaki Kakiage, Takeshi Yamanobe, Hiroki Uehara","doi":"10.1080/15685551.2023.2229641","DOIUrl":"https://doi.org/10.1080/15685551.2023.2229641","url":null,"abstract":"Various transition metal catalysts have been utilized for ethylene polymerization. Silver catalysts have attracted less attention as the catalysts, but are potential for production of high molecular weight polyethylene. Herein, we report that silver complexes with various N-heterocyclic carbene (NHC) ligands in combination with modified methylaluminoxane (MMAO) afford polyethylene with high molecular weight (melting point over 140°C). SEM observation showed that the produced polyethylene has ultra-high molecular weight. NMR investigation of the reaction between the silver complexes with organoaluminums indicate that the NHC ligands transfer from the silver complex to aluminum to produce NHC aluminum complexes. Ph3C[B(C6F5)4] abstract methyl group from the NHC aluminum complex to afford cationic aluminum complex. The NHC aluminum complex promoted ethylene polymerization in the presence of Ph3C[B(C6F5)4] and organoaluminums. NHC ligand also promoted ethylene polymerization in combination with MMAO to produce polyethylene with high melting point (140.7°C). Thus, the aluminum complexes are considered to be the actual active species in silver-catalyzed ethylene polymerization.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"182-189"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10324440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10545627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parallel synthesis of donor-acceptor π-conjugated polymers by post-element transformation of organotitanium polymer. 有机钛聚合物元素后转化平行合成供受体π共轭聚合物。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2233228

Yoshimasa Matsumura, Alvin Tanudjaja, Mizuki Fukushima, Makoto Higuchi, Shin Ogino, Makoto Ishidoshiro, Yasuyuki Irie, Hiroaki Imoto, Kensuke Naka, Ryoyu Hifumi, Shinsuke Inagi, Ikuyoshi Tomita

{"title":"Parallel synthesis of donor-acceptor π-conjugated polymers by post-element transformation of organotitanium polymer.","authors":"Yoshimasa Matsumura, Alvin Tanudjaja, Mizuki Fukushima, Makoto Higuchi, Shin Ogino, Makoto Ishidoshiro, Yasuyuki Irie, Hiroaki Imoto, Kensuke Naka, Ryoyu Hifumi, Shinsuke Inagi, Ikuyoshi Tomita","doi":"10.1080/15685551.2023.2233228","DOIUrl":"https://doi.org/10.1080/15685551.2023.2233228","url":null,"abstract":"The donor-acceptor type π-conjugated polymers having heterole units were prepared by the reaction of a regioregular organometallic polymer having both reactive titanacyclopentadiene and electron-donor thiophene-2,5-diyl units in the main chain with electrophiles such as diphenyltin dichloride, dichlorophenylphosphine, and diiodophenylarsine. For example, a polymer having electron-accepting phosphole unit was obtained in 54% yield whose number-average molecular weight (Mn) and molecular weight distribution (Mw/Mn) were estimated as 3,000 and 1.9, respectively. The obtained polymer exhibits a high highest occupied molecular orbital (HOMO) and low lowest unoccupied molecular orbital (LUMO) energy levels (-5.13 eV and -3.25 eV, respectively) due to the electron-donating thiophene and electron-accepting phosphole units. Reflecting upon the alternating structure of thiophene and phosphole, the polymer exhibits a band gap energy level (Eg) of 1.78 eV which is narrower than that of a derivative of poly(thiophene) (Eg = 2.25 eV).","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"190-197"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10327520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10564367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cascading Beta-oxidation Intermediates for the Polyhydroxyalkanoate Copolymer Biosynthesis by Metabolic Flux using Co-substrates and Inhibitors. 利用共底物和抑制剂代谢通量合成聚羟基烷酸酯共聚物的级联β -氧化中间体。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2179763

Geethu Madhusoodhanan, Shruthi Ks, Raghu Chandrashekar Hariharapura, Divyashree M Somashekara

{"title":"Cascading Beta-oxidation Intermediates for the Polyhydroxyalkanoate Copolymer Biosynthesis by Metabolic Flux using Co-substrates and Inhibitors.","authors":"Geethu Madhusoodhanan, Shruthi Ks, Raghu Chandrashekar Hariharapura, Divyashree M Somashekara","doi":"10.1080/15685551.2023.2179763","DOIUrl":"https://doi.org/10.1080/15685551.2023.2179763","url":null,"abstract":"Polyhydroxyalkanoates (PHAs) are biopolymers that are produced within the microbial cells in the presence of excess carbon and nutrient limitation. Different strategies have been studied to increase the quality and quantity of this biopolymer which in turn can be utilized as biodegradable polymers replacing conventional petrochemical plastics. In the present study, Bacillus endophyticus, a gram-positive PHA-producing bacterium, was cultivated in the presence of fatty acids along with beta-oxidation inhibitor acrylic acid. A novel approach for incorporating different hydroxyacyl groups provided using fatty acids as co-substrate and beta-oxidation inhibitors to direct the intermediates to co-polymer synthesis was experimented. It was observed that higher fatty acids and inhibitors had a greater influence on PHA production. The addition of acrylic acid along with propionic acid had a positive impact, giving 56.49% of PHA along with sucrose which was 1.2-fold more than the control devoid of fatty acids and inhibitors. Along with the copolymer production, the possible PHA pathway functional leading to the copolymer biosynthesis was hypothetically interpreted in this study. The obtained PHA was analyzed by FTIR and 1H NMR to confirm the copolymer production, which indicated the presence of poly3hydroxybutyrate-co-hydroxyvalerate (PHB-co-PHV), poly3hydroxybutyrate-co-hydroxyhexanoate (PHB-co-PHx).","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"1-14"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10824014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preparation and characterization of morphine gelatine microspheres. 吗啡明胶微球的制备和表征。

IF 1.8 4区化学

Designed Monomers and Polymers Pub Date : 2022-12-20 eCollection Date: 2023-01-01 DOI: 10.1080/15685551.2022.2158571

Xin Jin, Jun Ji, Yonghai Sun

{"title":"Preparation and characterization of morphine gelatine microspheres.","authors":"Xin Jin, Jun Ji, Yonghai Sun","doi":"10.1080/15685551.2022.2158571","DOIUrl":"10.1080/15685551.2022.2158571","url":null,"abstract":"Morphine is a widely used opioid analgesic. However, standard morphine dosages and administration methods exhibit a short half-life and pose a risk of respiratory depression. Sustained-release microspheres can deliver prolonged efficacy and reduce side effects. We present a new controlled-release morphine gelatine microsphere (MGM) prepared using an emulsification-crosslinking strategy. The gelatine microsphere design improves the bioavailability of morphine. And it not only increases the clinical analgesic efficacy but also the safety of clinical medication through a gradual, sustained release. Besides, we describe MGMs' preparation, release, pharmacodynamics, and pharmacokinetics. And the drug metabolism pathway. We calculate the release rate of morphine by measuring plasma morphine concentration over time and pharmacokinetic parameters. It optimized the manufacturing process of MGMs, which makes the analgesic effect have a longer duration. MGMs analgesic effect shows dose dependence. After they were administrated, MGMs were released more slowly. Peak concentration was reduced, and the relative bioavailability improved. It even reached 88.84%. Its pharmacokinetic process was consistent with the two-component first-order absorption model. MGMs deliver sustained-release and long-action pharmacokinetics. It shows design goals of improving drug bioavailability, prolonging drug residence time in vivo, and maintaining stable blood drug concentration.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"1-14"},"PeriodicalIF":1.8,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0