Designed Monomers and Polymers最新文献_第5页

Cascading Beta-oxidation Intermediates for the Polyhydroxyalkanoate Copolymer Biosynthesis by Metabolic Flux using Co-substrates and Inhibitors. 利用共底物和抑制剂代谢通量合成聚羟基烷酸酯共聚物的级联β -氧化中间体。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2023-01-01 DOI: 10.1080/15685551.2023.2179763

Geethu Madhusoodhanan, Shruthi Ks, Raghu Chandrashekar Hariharapura, Divyashree M Somashekara

{"title":"Cascading Beta-oxidation Intermediates for the Polyhydroxyalkanoate Copolymer Biosynthesis by Metabolic Flux using Co-substrates and Inhibitors.","authors":"Geethu Madhusoodhanan, Shruthi Ks, Raghu Chandrashekar Hariharapura, Divyashree M Somashekara","doi":"10.1080/15685551.2023.2179763","DOIUrl":"https://doi.org/10.1080/15685551.2023.2179763","url":null,"abstract":"Polyhydroxyalkanoates (PHAs) are biopolymers that are produced within the microbial cells in the presence of excess carbon and nutrient limitation. Different strategies have been studied to increase the quality and quantity of this biopolymer which in turn can be utilized as biodegradable polymers replacing conventional petrochemical plastics. In the present study, Bacillus endophyticus, a gram-positive PHA-producing bacterium, was cultivated in the presence of fatty acids along with beta-oxidation inhibitor acrylic acid. A novel approach for incorporating different hydroxyacyl groups provided using fatty acids as co-substrate and beta-oxidation inhibitors to direct the intermediates to co-polymer synthesis was experimented. It was observed that higher fatty acids and inhibitors had a greater influence on PHA production. The addition of acrylic acid along with propionic acid had a positive impact, giving 56.49% of PHA along with sucrose which was 1.2-fold more than the control devoid of fatty acids and inhibitors. Along with the copolymer production, the possible PHA pathway functional leading to the copolymer biosynthesis was hypothetically interpreted in this study. The obtained PHA was analyzed by FTIR and 1H NMR to confirm the copolymer production, which indicated the presence of poly3hydroxybutyrate-co-hydroxyvalerate (PHB-co-PHV), poly3hydroxybutyrate-co-hydroxyhexanoate (PHB-co-PHx).","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"1-14"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9970204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10824014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preparation and characterization of morphine gelatine microspheres. 吗啡明胶微球的制备和表征。

IF 1.8 4区化学

Designed Monomers and Polymers Pub Date : 2022-12-20 eCollection Date: 2023-01-01 DOI: 10.1080/15685551.2022.2158571

Xin Jin, Jun Ji, Yonghai Sun

{"title":"Preparation and characterization of morphine gelatine microspheres.","authors":"Xin Jin, Jun Ji, Yonghai Sun","doi":"10.1080/15685551.2022.2158571","DOIUrl":"10.1080/15685551.2022.2158571","url":null,"abstract":"Morphine is a widely used opioid analgesic. However, standard morphine dosages and administration methods exhibit a short half-life and pose a risk of respiratory depression. Sustained-release microspheres can deliver prolonged efficacy and reduce side effects. We present a new controlled-release morphine gelatine microsphere (MGM) prepared using an emulsification-crosslinking strategy. The gelatine microsphere design improves the bioavailability of morphine. And it not only increases the clinical analgesic efficacy but also the safety of clinical medication through a gradual, sustained release. Besides, we describe MGMs' preparation, release, pharmacodynamics, and pharmacokinetics. And the drug metabolism pathway. We calculate the release rate of morphine by measuring plasma morphine concentration over time and pharmacokinetic parameters. It optimized the manufacturing process of MGMs, which makes the analgesic effect have a longer duration. MGMs analgesic effect shows dose dependence. After they were administrated, MGMs were released more slowly. Peak concentration was reduced, and the relative bioavailability improved. It even reached 88.84%. Its pharmacokinetic process was consistent with the two-component first-order absorption model. MGMs deliver sustained-release and long-action pharmacokinetics. It shows design goals of improving drug bioavailability, prolonging drug residence time in vivo, and maintaining stable blood drug concentration.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":"26 1","pages":"1-14"},"PeriodicalIF":1.8,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10428168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dimanganese decacarbonyl catalyzed visible light induced ambient temperature depolymerization of poly(methyl methacrylate). 二羰基二锰催化可见光诱导的室温下聚甲基丙烯酸甲酯解聚。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-10-17 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2135730

Zeynep Arslan, Hüseyin Cem Kiliclar, Yusuf Yagci

{"title":"Dimanganese decacarbonyl catalyzed visible light induced ambient temperature depolymerization of poly(methyl methacrylate).","authors":"Zeynep Arslan, Hüseyin Cem Kiliclar, Yusuf Yagci","doi":"10.1080/15685551.2022.2135730","DOIUrl":"https://doi.org/10.1080/15685551.2022.2135730","url":null,"abstract":"Recent years have witnessed an enormous development in photoinduced systems, opening up possibilities for advancements in industry and academia in terms of green chemistry providing environmentally friendly conditions and spatiotemporal control over the reaction medium. A vast number of research have been conducted on photoinduced systems focusing on the development of new polymerization methods, although scarcely investigated, depolymerization of the synthesized polymers by photochemical means is also possible. Herein, we provide a comprehensive study of visible light induced dimanganese decacarbonyl (Mn2(CO)10) assisted depolymerization system for poly(methyl methacrylate) with chlorine chain end prepared by Atom Transfer Radical Polymerization. Contrary to the conventional procedures demanding high temperatures, the approach offers ambient temperature for the photodepolymerization process. This novel light-controlled concept is easily adaptable to macroscales and expected to promote further research in the fields matching with the environmental concerns.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"271-276"},"PeriodicalIF":1.6,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586668/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40664744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Synthesis of homo- and copolymer containing sulfonic acid via atom transfer radical polymerization. 原子转移自由基聚合法合成含磺酸的同聚物和共聚物。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-09-19 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2126092

Md Wali Ullah, Naoki Haraguchi, Md Azgar Ali, Md Rabiul Alam, Samiul Islam Chowdhury

{"title":"Synthesis of homo- and copolymer containing sulfonic acid via atom transfer radical polymerization.","authors":"Md Wali Ullah, Naoki Haraguchi, Md Azgar Ali, Md Rabiul Alam, Samiul Islam Chowdhury","doi":"10.1080/15685551.2022.2126092","DOIUrl":"https://doi.org/10.1080/15685551.2022.2126092","url":null,"abstract":"Well-defined functional poly(p-phenyl styrenesulfonate) and poly(p-phenyl styrene-sulfonate-co-styrene) were successfully synthesized by the atom transfer radical polymerization (ATRP) using CuBr/bpy(PMDETA) catalyst and 1-phenylethyl bromide (1-PEBr) as an ATRP initiator in diphenyl ether (DPE) or dimethyl formamide (DMF). In both homo- and copolymers, the CuBr/PMDETA catalytic system in DPE or DME showed higher yield than CuBr/bpy and the polydispersity index (PDI) of polymer was low. Using PMDETA or bpy as a ligand in DMF, the high yield with high PDI was obtained than in DPE. We found that the CuBr/PMDETA catalyzed ATRP of p-phenyl styrenesulfonate and copolymerization with styrene comonomer in DPE proceeded in a controlled manner. The polymers containing sulfonic acid were obtained by the chemical deprotection of protecting group, followed by acidification. The molecular structure, molecular weights and thermal properties of the copolymers were determined by nuclear magnetic resonance (1H NMR) spectroscopy, Fourier transform infrared (FT-IR) spectroscopy, size exclusion chromatography (SEC), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA), respectively.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"261-270"},"PeriodicalIF":1.6,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40392823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Co(II) compound: photocatalytic activity and application value in trigeminal neuralgia with minimally invasive interventional therapy guided by CT. 一种Co(II)化合物:CT引导下微创介入治疗三叉神经痛的光催化活性及应用价值

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-08-26 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2115207

Shu-Wen Wang, Ling-Chao Li

引用次数: 0

Polyester-releasing sesamin by electrospinning technique for the application of bone tissue engineering. 静电纺丝技术释聚酯芝麻素在骨组织工程中的应用。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-08-12 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2111857

Vachira Choommongkol, Jetsada Ruangsuriya, Panawan Suttiarporn, Winita Punyodom, Boontharika Thapsukhon

{"title":"Polyester-releasing sesamin by electrospinning technique for the application of bone tissue engineering.","authors":"Vachira Choommongkol, Jetsada Ruangsuriya, Panawan Suttiarporn, Winita Punyodom, Boontharika Thapsukhon","doi":"10.1080/15685551.2022.2111857","DOIUrl":"https://doi.org/10.1080/15685551.2022.2111857","url":null,"abstract":"Sesamin, a significant lignin compound isolated from sesame (Sesamum indicum Linn), is well known for its antioxidant, anti-inflammatory, and tissue growth promotion properties. Bioabsorbable poly(ε-caprolactone) (PCL) is also a well-known polymer applied to various fields of medicine as biomaterials. The main objective of this research was to produce a prototype material from PCL and sesamin by electrospinning technique for bone tissue engineering applications. Dichloromethane and dimethylformamide (7:3) mixture was used as the solvent system for fabrication of PCL nanofiber with different loads of sesamin concentrations (1-6 wt%). The crystallinity levels decreasing and the entrapment efficiency increasing (86.87%-93.97%) were observed while sesamin concentrations were increased. The infrared spectra of electrospun mats confirmed that sesamin corporated into fibrous networks. The sesamin-loaded PCL nanofibrous membranes showed a significant release of sesamin in the range of 1.28-8.16 μg/mL within 10 weeks. The release data were fitted to zero order, first order, Higuchi and Korsmeyer-Peppas models to evaluate sesamin-releasing mechanisms and kinetics. The releasing kinetics of sesamin followed the Fickian diffusion mechanism of Korsmeyer-Peppas (R2 = 0.99). In vitro experiments with an osteosarcoma cell line (MG-63) revealed cell attachment, biocompatibility, and promotion of bone marker expression, the alkaline phosphatase (ALP) activity were studied. The electrospun PCL nanofiber loaded with sesamin had the potential as a scaffold for sesamin delivery to bone cells and applications in biomedicine.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"231-244"},"PeriodicalIF":1.6,"publicationDate":"2022-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40422470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Design of novel temperature-resistant and salt-tolerant acrylamide-based copolymers by aqueous dispersion polymerization. 新型耐温耐盐丙烯酰胺基共聚物的水分散聚合设计。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-08-11 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2111845

Xiang Li, Ye Ju, Yongkang Jia, Fenggang Liu, Guangpu Liu, Shuo Wang, Haoyi Wang, Shihua Mao, Jintao Yang, Guangyan Du

{"title":"Design of novel temperature-resistant and salt-tolerant acrylamide-based copolymers by aqueous dispersion polymerization.","authors":"Xiang Li, Ye Ju, Yongkang Jia, Fenggang Liu, Guangpu Liu, Shuo Wang, Haoyi Wang, Shihua Mao, Jintao Yang, Guangyan Du","doi":"10.1080/15685551.2022.2111845","DOIUrl":"https://doi.org/10.1080/15685551.2022.2111845","url":null,"abstract":"Development of polymer-based flooding technology to improve oil recovery efficiency, water dispersion copolymerization of acrylamide, cationic monomer methacryloxyethyltrimethyl ammonium chloride (METAC), and anionic monomer acrylic acid (AA) were carried out in aqueous ammonium sulfate solution with polyvinyl pyrrolidone (PVP) as the stabilizer. The copolymers were characterized by 1H-NMR, FT-IR, TG, and SEM to confirm that they were prepared successfully and exhibited excellent salt-resistant property. Moreover, the effect of the aqueous solution of ammonium sulfate (AS) concentration, stabilizer concentration, and initiator concentration on the viscosity and size were systematically investigated. To further improve the thermal endurance properties of copolymer, hydrophobic monomers with different alkyl chain lengths were added to the above system. The acrylamide-based quadripolymer possessed prominent thermal and salt endurance properties by utilizing the advantages of zwitterionic structure and hydrophobic monomer. With the temperature rising, the viscosity retention could reach 70.2% in the water and 63.8% in the saline. This work had expected to provide a new strategy to design polymers with excellent salinity tolerance and thermal-resistance performances.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"220-230"},"PeriodicalIF":1.6,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40423111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Drug Release and Cytotoxicity of Hyaluronic Acid and Zinc Oxide Gels, An In-Vitro Study. 透明质酸和氧化锌凝胶的体外药物释放和细胞毒性研究。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-07-24 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2099647

Jaahnavi Lanka, Santhosh Kumar, Mohana Kumar B, Shama Rao, Shivaprasad Gadag, Usha Y Nayak

{"title":"Drug Release and Cytotoxicity of Hyaluronic Acid and Zinc Oxide Gels, An In-Vitro Study.","authors":"Jaahnavi Lanka, Santhosh Kumar, Mohana Kumar B, Shama Rao, Shivaprasad Gadag, Usha Y Nayak","doi":"10.1080/15685551.2022.2099647","DOIUrl":"https://doi.org/10.1080/15685551.2022.2099647","url":null,"abstract":"Hyaluronic acid (HA) is a naturally occurring biopolymer, with a remarkable wound healing property. Zinc-oxide non-eugenol is a material widely used for periodontal dressing in dentistry. However, it has been reported that zinc oxide non-eugenol is toxic to osteoblasts and fibroblasts. Hence, the present study aimed to evaluate the drug release and cytotoxicity of HA and zinc-oxide gels. Hydrogels of HA and zinc oxide were formulated with carbopol as a carrier. In vitro drug release was performed by UV spectrophotometry, dialysis, and vial bag methods. Cytotoxicity assessment of HA and zinc-oxide gels was performed in human periodontal ligament fibroblasts (HPdLF) and human gingival fibroblasts (hGFs). An inverted phase-contrast microscope was used to assess the morphological changes. At 24 and 48 hr, HPdLF cells showed the highest viability in 0.1% low molecular weight-HA (LMW-HA) with a median value of 131.9, and hGFs showed the highest viability in 5% LMW-HA with a median of 129.56. The highest viability of HPdLF cells was observed in 5% high molecular weight-HA (HMW-HA), with a median value of 127.11. hGFs showed the highest viability in 1% HMW-HA with a median value of 97.99. Within the limitations of the present study, we concluded that LMW-HA is more efficient than HMW-HA. Both HPdLF and hGF cells showed complete cell morbidity with zinc-oxide hydrogels. Therefore, zinc oxide-based gels in concentrations as low as 9% could be toxic intraorally to soft tissues that harbor gingival and periodontal ligament fibroblasts.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"212-219"},"PeriodicalIF":1.6,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9327778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40573424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Two new Cd(II)/Zn(II) coordination polymers: luminescence properties and synergistic treatment activity with ultrasound therapy on uterine fibroids. 两种新型Cd(II)/Zn(II)配位聚合物的发光特性及其与超声治疗子宫肌瘤的协同治疗活性。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-06-20 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2088976

Hong-Mei Liu, Xiao-Na Shang

{"title":"Two new Cd(II)/Zn(II) coordination polymers: luminescence properties and synergistic treatment activity with ultrasound therapy on uterine fibroids.","authors":"Hong-Mei Liu, Xiao-Na Shang","doi":"10.1080/15685551.2022.2088976","DOIUrl":"https://doi.org/10.1080/15685551.2022.2088976","url":null,"abstract":"Through the self-assembly reaction of 5-substituted isophthalic acid and bis(imidazolyl) ligands with Cd(II) ion or Zn(II) ion, two new coordination polymers with the chemical formulae of [Cd(5-meo-ip)(bmip)]n (1) and [Zn(5-pro-ip)(bip)]n·2 n(H2O) (2) (5-meo-H2ip = 5-methoxyisophthalic acid, 5-pro-H2ip = 5-propoxyisophthalic acid, bmip = 1,3-bis(2-methylimidazolyl)propane bip = 1,3-bis(imidazolyl)propane) were successfully obtained and structurally characterized by a series of characterization techniques. Moreover, compounds 1-2 show intense blue luminescence at room temperature. Furthermore, the assessment of their treatment activity on the uterine fibroids combined with ultrasound therapy was evaluated and the specific mechanism was investigated at the same time. Firstly, the effect of compound treatment on uterine fibroids apoptosis was detected via flow cytometry. Next, the apoptotic signaling pathway activation was detected through the Caspase-3 and Caspase-8 Activity Assay Kit.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"197-204"},"PeriodicalIF":1.6,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9225708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40399234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis of carbazole-based dendritic conjugated polymer: a dual channel optical probe for the detection of I^- and Hg². 咔唑基枝状共轭聚合物的合成:用于检测I-和Hg2的双通道光学探针。

IF 1.6 4区化学

Designed Monomers and Polymers Pub Date : 2022-06-20 eCollection Date: 2022-01-01 DOI: 10.1080/15685551.2022.2088977

Yimin Wu, Ling Zhang, Fudong Ma, Tao Ding, Ablikim Obolda

{"title":"Synthesis of carbazole-based dendritic conjugated polymer: a dual channel optical probe for the detection of I- and Hg2.","authors":"Yimin Wu, Ling Zhang, Fudong Ma, Tao Ding, Ablikim Obolda","doi":"10.1080/15685551.2022.2088977","DOIUrl":"https://doi.org/10.1080/15685551.2022.2088977","url":null,"abstract":"A new type of carbazole-based blue-emitting dendritic conjugated polymer, poly[(9,9-dioctyl)-2,7-fluorene-co-4,4',4\"-triphenylamine-co-9-(4-(9H-carbazol-9-yl)butyl)-3,6-carbazole](P), was successfully synthesized by Suzuki coupling reaction. Chemical structures of monomers and polymer were verified by FI-IR and 1HNMR characterizations. We found that polymer showed a special selectivity and high sensitivity for I-. With the addition of I-, the fluorescent polymer solution was obviously quenched. The polymer showed a special detection effect on I-. However, the fluorescent polymer was obviously restored when Hg2+ was added to the P/I- system due to the large complexation between I- and Hg2+. The anti-interference experiments of probe P/I- showed that other background cations have a slight influence on detecting Hg2+, and the calculated detection limit of Hg2+ reached 9.7 × 10-8 M, which could be a potential application for a two-channel cyclic detection of I- and Hg2+. Additionally, it was found that the theoretical values were in agreement with the experimental data.","PeriodicalId":11170,"journal":{"name":"Designed Monomers and Polymers","volume":" ","pages":"184-196"},"PeriodicalIF":1.6,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/88/76/TDMP_25_2088977.PMC9225711.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40399235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2