Current Psychiatry Reports最新文献

{"title":"Suicide Risk in Glioblastoma Multiforme: A Brief Review of Risk Factors, Screening, and Prevention.","authors":"Nick Waldvogel, Hyo Ryu, Michelle Riba","doi":"10.1007/s11920-026-01711-2","DOIUrl":"10.1007/s11920-026-01711-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>Glioblastoma multiforme (GBM) is an aggressive primary brain tumor associated with poor prognosis, rapid functional decline, and psychological distress. An updated review of the literature is lacking, despite that patients with GBM appear to be among the highest risk for suicide among cancer patients. This review summarizes up-to-date evidence of suicide risk factors, screening approaches, and suicide mitigation strategies in patients with GBM.</p><p><strong>Recent findings: </strong>Suicide risk is the highest in the first year following GBM diagnosis. It is also associated with older age, male gender, and tumor-related factors such as supratentorial location. Other factors such as neurocognitive decline and poor functional status may also contribute. Evidence emerging from broader oncology populations suggests that demoralization and existential distress may be factors, though these have not been studied in GBM cohorts. Treatment-related psychiatric adverse effects from corticosteroids, anti-epileptic drugs, chemotherapy, and radiotherapy may also influence psychiatric illness and mediate suicide risk. Screening tools such as the Patient Health Questionnaire-9, Hospital Anxiety and Depression Scale, and Colombia-Suicide Severity Rating Scale have been effectively used to screen for suicide in conjunction with clinical interviewing in GBM patients. Evidence-based suicide reduction interventions include psychotherapy, safety planning, lethal means restriction, and caregiver support. GBM is a diagnosis that is associated with higher rates of suicide than almost all other cancers, and the extant literature identifies demographic and tumor features that are associated with suicide in this population. Effective interventions exist to identify and support these patients. Future studies should systematically measure risk factors identified in broader oncology populations to identify additional GBM-specific risk factors for suicide.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13468844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148721618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Family Support in Adolescence and its Impact on Suicide risk: A Narrative Review.","authors":"Irene Caro-Cañizares, Ana Huertes-Del Arco, Garazi Laseca Zaballa, Elena Brenlla, Juan J Carballo","doi":"10.1007/s11920-026-01713-0","DOIUrl":"10.1007/s11920-026-01713-0","url":null,"abstract":"<p><strong>Purpose of the review: </strong>This narrative review focuses on the relationship between perceived family support and suicide risk in adolescence (10-19 years, with some evidence extending into young adulthood), emphasizing the role of family support as a buffer against stressful life events.</p><p><strong>Recent findings: </strong>Suicide and suicidal behavior among adolescents are one of the major social and health problems of the 21st century. An emerging body of studies has explored the risk and protective factors independently, but less specific research has examined how these factors relate to each other. Specifically, family support appears to be one of the most significant attenuators of suicide risk in the presence of stressful life events or adverse circumstances. It is also worth considering the possible differential effects depending on other variables such as gender or age.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in the Understanding of the Genetics of Obsessive-Compulsive Disorder (OCD).","authors":"A Christelle Doppenberg, Carolina Cappi, Nora I Strom, James J Crowley, Dale R Nyholt, Brittany L Mitchell, Eske M Derks","doi":"10.1007/s11920-026-01705-0","DOIUrl":"10.1007/s11920-026-01705-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review summarizes recent advances in the genetics of Obsessive-Compulsive Disorder (OCD), their contribution to understanding disorder biology, and implication for clinical translation.</p><p><strong>Recent findings: </strong>Recent GWAS identified 30 genome-wide significant loci and prioritized 25 putatively causal genes. Rare variant studies implicated specific genes, including CHD8, CELSR3, SLITRK5, and QRICH1. Evidence from common and rare variants support brain- and immune-related pathways. Genetic overlap with obsessive compulsive symptoms and other psychiatric disorders indicate shared underlying biology. Current evidence is largely based on individuals of European ancestry, although global efforts are underway to improve ancestral diversity in OCD genetics. Given the urgent need for improved treatment, genetically informed clinical translation approaches hold promise, including pharmacogenetics and drug repurposing. Recent advances in OCD genetics support a highly polygenic architecture, implicate specific neuro-biological and immune pathways, and provide new opportunities for clinical translation.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13428006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Data to Early Diagnosis: Artificial Intelligence as a Tool to Support Screening and Detection of Autism Spectrum Disorder in Childhood.","authors":"Andrea Catalina Mahecha Ballesteros, Juanita Valeria García Bello, Eleaine Scarlet González Zuñiga, Shayra Nicole Peinado Páez, Erwin Hernando Hernández Rincón","doi":"10.1007/s11920-026-01683-3","DOIUrl":"10.1007/s11920-026-01683-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>Autism spectrum disorder (ASD) is a neurodevelopmental condition with significant implications for childhood development and public health. Early detection is critical to enable timely intervention, yet access to specialised assessment remains limited in many settings. In this context, artificial intelligence (AI) has gained increasing attention as a potential tool to support early ASD screening. This review summarises recent evidence on the use of AI for the screening and early detection in childhood.</p><p><strong>Recent findings: </strong>Recent studies generally report favorable results for AI-based approaches, particularly in pediatric populations. Multimodal models that integrate data from questionnaires, video and audio sources tend to outperform single modality approaches, with reported improvements in accuracy and sensitivity. However, most studies remain experimental, with small sample sizes and limited validation in real world clinical environments. AI shows promise as a supportive tool for early screening, but current evidence supports its use as a complement to, rather than replacement for, clinical assessment. Further validation in routine practice is needed before widespread implementation.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148629844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"It Doesn't Matter Where OCD Comes From,\" or Does It?","authors":"Caitlin M Pinciotti, Ryan J McCarty, Gabriella T Ponzini","doi":"10.1007/s11920-026-01708-x","DOIUrl":"10.1007/s11920-026-01708-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review critically evaluates the claim that etiology is not relevant to cognitive behavioral therapy (CBT) for obsessive-compulsive disorder (OCD). Research on the clinical presentation and treatment outcomes associated with traumatic/stressor and biological etiologies is presented.</p><p><strong>Recent findings: </strong>The extant literature demonstrates varying clinical utility across the reviewed etiologies. Traumatic/stressor etiologies show the most consistent and robust evidence of clinical utility, demonstrating compelling associations with clinical presentation and treatment outcomes, while also being amenable to existing evidence-based approaches. Medical conditions (e.g., Pediatric Acute onset Neuropsychiatric Syndrome) and neurobiological factors also demonstrate considerable associations with OCD presentation, yet effective treatments are more variable. Genetics research is still emerging, with unclear clinical utility based on presently available treatments. Etiology has variable clinical utility for OCD. We argue that some etiological mechanisms become maintenance factors that are relevant treatment targets, and call for continued research in these emerging domains.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13424220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148618698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Suicidality beyond Depression: a Systematic Review of Risk Profiles and Prevention Gaps.","authors":"Valentina Baldini, Martina Gnazzo, Giorgia Varallo, Diana De Ronchi, Marco Carotenuto, Andrea Fiorillo","doi":"10.1007/s11920-026-01706-z","DOIUrl":"10.1007/s11920-026-01706-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>Suicidal ideation and behavior during the postpartum period are increasingly recognized as important contributors to maternal morbidity and mortality, particularly in high-income countries. Although postpartum depression is a well-established risk factor, emerging evidence suggests that suicidality may also occur independently and therefore remain underrecognized in clinical practice. This systematic review aimed to synthesize current evidence regarding the prevalence of suicidal ideation and behavior in the postpartum period and to identify associated risk factors.</p><p><strong>Recent findings: </strong>A systematic search of PubMed, Web of Science, EMBASE, and PsycINFO was conducted up to March 2025 following PRISMA guidelines. Twenty studies met inclusion criteria, encompassing 352,726 postpartum women across diverse international settings. Reported prevalence of suicidal ideation ranged from 2.2% to over 50%, depending on the population studied and assessment methods used. The most frequently identified risk factors included postpartum depression, anxiety, trauma history, intimate partner violence, unplanned pregnancy, low socioeconomic status, low social support, and adverse childhood experiences. Notably, several studies reported suicidal ideation even in the absence of clinical depression. Only a limited number of studies addressed preventive interventions. Postpartum suicidality appears to be a multifactorial phenomenon that cannot be explained solely by depressive symptomatology. The findings highlight the need for broader screening strategies that incorporate psychosocial and trauma-related factors in addition to depression. Integrated and trauma-informed approaches to screening and prevention may improve early identification of at-risk individuals. Future research should prioritize longitudinal designs and culturally sensitive investigations to better inform prevention and intervention strategies.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13408136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148590804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Worry and Anxiety in the Era of Early Diagnosis and Disease Modifying Treatment for Alzheimer's Disease.","authors":"Shana D Stites, Katherine Lee, Carolyn Kuz, David Mandell, Hillary R Bogner, Rebecca Brown","doi":"10.1007/s11920-026-01704-1","DOIUrl":"10.1007/s11920-026-01704-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>Psychologists and psychiatrists are well-positioned to be at the forefront of addressing the challenges posed by anxiety in early diagnosis and treatment of Alzheimer's disease (AD) dementia that are unfolding in primary care settings. The present article provides a summary of emerging areas in Alzheimer's disease testing and research to guide clinical decisions and research pursuits.</p><p><strong>Recent findings: </strong>The present article provides an overview of how anxiety is understood in early diagnosis of dementia due to AD, its influence in AD-related mechanisms, and the implications of these findings on current research practices. We conducted focused literature reviews between January and June 2026 and synthesized the information to provide a narrative review. Overall, the clinical roles of anxiety in AD dementia are expanding- from being viewed primarily as reactions to cognitive decline to serving as informative features of the diagnostic process and clinical course of the disease.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13407960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148590799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obsessive-Compulsive Disorder in three understudied populations: A review of Latino, Black, and Sexual & Gender Minority Individuals.","authors":"Ryan J McCarty, Ogechi C Onyeka, Caitlin M Pinciotti, Andrew D Wiese, Eric A Storch","doi":"10.1007/s11920-026-01707-y","DOIUrl":"10.1007/s11920-026-01707-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review overviews the research base for obsessive-compulsive disorder (OCD) among three historically understudied populations; Latino/Latin Americans, Black/African Americans, and Sexual and Gender Minority individuals.</p><p><strong>Recent findings: </strong>Findings suggest that while core OCD symptoms are broadly similar across groups, sociocultural factors such as discrimination, minority stress, stigma, family context, spirituality, and access to care significantly influence symptom presentation, severity, and treatment utilization. Recent studies have evaluated assessment tools and provided evidence supporting exposure and response prevention, while emphasizing the importance of culturally responsive assessment and treatment. Large-scale initiatives are also improving representation in OCD research and addressing longstanding disparities in knowledge and care. OCD presents similarly across diverse populations, but cultural and contextual factors shape symptom expression and treatment experiences. Future research should prioritize representative samples, culturally informed assessment, and greater access to evidence-based care.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13401574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148590757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol Use and Operational Readiness in the U.S. Active-duty Military: A Review of Burden, Culture, and Barriers to Care.","authors":"Rebecca Lobach, Rohul Amin, Sarah Maggio, Kathleen Huber","doi":"10.1007/s11920-026-01700-5","DOIUrl":"10.1007/s11920-026-01700-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review examines alcohol use among U.S. military personnel, including patterns of use across the full spectrum of consumption, including behaviors not meeting the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for alcohol use disorder. It examines the prevalence and aspects of military life, culture, and context that may serve as important contributors to and risk factors for developing unhealthy, excessive, or disordered alcohol use. This review discusses efforts towards prevention, interventions, and policies pertaining to alcohol use in the military and identifies areas that would benefit from future research. Alcohol use remains a critical determinant of military health, operational readiness, and force lethality. While the Department of War (DoW) has invested in developing a modern framework for harm reduction, rates of binge and heavy drinking in the military continue to exceed that of civilians. Unique challenges of military life, including operational and institutional stressors, stigma and barriers to care, and factors of military social culture and context, coalesce to normalize and sustain unhealthy alcohol consumption within the force. Future efforts must focus on evaluating current interventions and tailoring evidence-based programs to address the needs of a diverse military population.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13380565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated Specialty Care: A Review of the Current State.","authors":"Laurie C Ivey, Anne-Stuart Bell, Mary Taylor Goeltz, Emma Gilchrist","doi":"10.1007/s11920-026-01699-9","DOIUrl":"10.1007/s11920-026-01699-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>The paper reviews the integrated specialty care literature from the past 5 years, summarizes themes, and highlights next steps for continuing to move the field forward.</p><p><strong>Recent findings: </strong>Forty-six articles have been written on integrated specialty care in the last 5 years. People are using generic integration principles, adapting primary care models, and outlining new adaptations and frameworks for their specialty settings. Providers continue to find integration important to their practice and their professional satisfaction. Positive impacts continue to be made on patient outcomes, including prevention. There is some evidence for decreases in utilization. Barriers continue with respect to reimbursement and financial support. Integrating behavioral health (BH) into specialty care is a beneficial endeavor for providers and patients alike. New trends in integration continue to emerge as additional specialty practices integrate. Reducing financial barriers while engaging in efforts to build a competent BH workforce are imperatives.</p>","PeriodicalId":11057,"journal":{"name":"Current Psychiatry Reports","volume":"28 1","pages":""},"PeriodicalIF":7.5,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}