Current opinion in insect science最新文献_第5页

Recent advances and applications of single-cell sequencing in insects 昆虫单细胞测序的最新进展及应用。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-10-29 DOI: 10.1016/j.cois.2025.101455

Nishtha Nayyar , Surjeet Kumar Arya , Douglas A Harrison , Subba Reddy Palli

{"title":"Recent advances and applications of single-cell sequencing in insects","authors":"Nishtha Nayyar , Surjeet Kumar Arya , Douglas A Harrison , Subba Reddy Palli","doi":"10.1016/j.cois.2025.101455","DOIUrl":"10.1016/j.cois.2025.101455","url":null,"abstract":"<div><div>Single-cell genomic technologies are transforming insect science, shifting the field from basic description to functional and mechanistic research. These methods provide remarkable insights into insect physiology, development, immunity, and evolution by enabling detailed analysis of cellular diversity and molecular complexity. The rapid advancement of single-cell multi-omics technologies has made it possible to explore transcriptomic, epigenomic, proteomic, and metabolic levels, offering a comprehensive view of molecular dynamics within cells. New techniques also hold promise for high-throughput spatial transcriptomics that reveal tissue organization at subcellular resolution. The effectiveness of these technologies has greatly improved due to concurrent progress in analytical tools and deep learning algorithms capable of integrating all outputs for unprecedented biological insights. Together, these innovations have led to exciting discoveries in insect biology in a short period. This review highlights recent progress in single-cell genomics, discusses new perspectives gained in insect biology, and examines future directions for this technology from an entomological standpoint.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101455"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145421468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Small RNAs in insects: emerging classes and functions 昆虫中的小rna：新出现的类别和功能。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-11-09 DOI: 10.1016/j.cois.2025.101458

Doga Cedden , Gözde Güney

{"title":"Small RNAs in insects: emerging classes and functions","authors":"Doga Cedden , Gözde Güney","doi":"10.1016/j.cois.2025.101458","DOIUrl":"10.1016/j.cois.2025.101458","url":null,"abstract":"<div><div>Insects produce diverse small RNAs (sRNAs) that play important roles in gene regulation and immunity, and some are being exploited as species-specific pest control strategies. Here, we review recent advances in insect sRNA biology. First, we summarize the canonical classes, microRNAs (miRNAs), small interfering RNAs (siRNAs), and PIWI-interacting RNAs (piRNAs). Next, we highlight emerging functions for transfer RNA-derived sRNAs (tsRNAs) in development and stress responses. We highlight that mechanistic studies are now beginning to link sRNAs to various biological phenomena using methods such as RNA sequencing and degradomics in combination with functional validations. We outline design features that increase the efficacy of double-stranded RNA (dsRNA) derived siRNAs and note that siRNAs appear to play a limited part in transposon control compared with piRNAs. We discuss emerging roles of piRNAs in reproduction and sex determination that suggest potential pest control strategies. Lastly, we highlight emerging evidence for cross-kingdom miRNAs delivered by insects to plants to facilitate herbivory, and conversely, plant miRNAs that may be transferred to insects to regulate their physiology. Overall, we argue that our understanding of insect sRNAs is rapidly expanding, which has implications for novel pest management strategies.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101458"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145494263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging sex determination systems for genetic biocontrol of dipteran pests 利用性别决定系统对双翅目害虫进行遗传生物防治。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-09-23 DOI: 10.1016/j.cois.2025.101439

Maxwell J Scott , Zhijian Tu

{"title":"Leveraging sex determination systems for genetic biocontrol of dipteran pests","authors":"Maxwell J Scott , Zhijian Tu","doi":"10.1016/j.cois.2025.101439","DOIUrl":"10.1016/j.cois.2025.101439","url":null,"abstract":"<div><div>Genetic biocontrol is an increasingly important way to suppress insect pest populations and to mitigate their economic and health impact. One key advantage is that it is species-specific, as it relies on the mating of released males with wild females to either suppress or modify populations. The latter is through rendering females incompetent at disease transmission. Sex separation is critical to ensure the efficiency of these control programs, and it is essential in the case of vector control to avoid releasing females that can transmit pathogens. Modern genetic methods provide the opportunity to target or manipulate components of the sex determination systems to facilitate genetic biocontrol with new means to effectively accomplish sex-specific selection, lethality, or sterility. For example, sex-specific splicing elements in genes in the sex determination pathway are used to produce sex-specific markers. Sex-linked recessive lethal alleles are used to differentially eliminate the transgene-marked sex chromosome from males to produce nontransgenic males. Knocking out or knocking down sex-specific isoforms of genes in the sex determination pathway is employed to confer female-specific lethality or sterility. Sex determination pathways and sex chromosomes are also targeted for gene drives that suppress pest populations by introducing extreme sex ratio biases. Here, we review these and other recent advances in genetic technologies for pest control that have benefited from knowledge of sex determination systems in Diptera.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101439"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Integrating mosquito genomics into simulation modeling: opportunities for better-informed biocontrol 将蚊子基因组学整合到模拟建模中：更好地了解生物防治的机会。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-10-27 DOI: 10.1016/j.cois.2025.101456

Gordana Rašić , John M Marshall

{"title":"Integrating mosquito genomics into simulation modeling: opportunities for better-informed biocontrol","authors":"Gordana Rašić , John M Marshall","doi":"10.1016/j.cois.2025.101456","DOIUrl":"10.1016/j.cois.2025.101456","url":null,"abstract":"<div><div>Mosquito-borne diseases remain a major global health burden, and novel biocontrol tools are quickly advancing from the laboratory to the field. Mathematical models play a central role in evaluating these interventions, yet their predictive accuracy depends on robust parameterization. Population genomics presents a powerful opportunity to address this challenge. Here, we review progress at the interface between mosquito genomics and biocontrol modeling, highlighting how genomic data have informed our understanding of mosquito population structure, standing genetic variation at gene drive target sites, and sources of resurgence for suppressed populations. We also discuss frontiers, including new approaches to quantifying gene flow, mating behaviors, and inbreeding depression, all of which shape intervention outcomes. By tapping this potential to better quantify our understanding of mosquito ecology, modelers can develop context-specific models with better predictive accuracy, supporting efficacy and risk assessment, design of field trials and interventions, and promotion of regulation and public trust.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101456"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145399952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An intricate evolutionary connection between meiotic drive and sex 减数分裂驱动和性之间复杂的进化联系。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-10-15 DOI: 10.1016/j.cois.2025.101452

Cécile Courret, Catherine Montchamp-Moreau, Richard Cordaux, Clément Gilbert

{"title":"An intricate evolutionary connection between meiotic drive and sex","authors":"Cécile Courret, Catherine Montchamp-Moreau, Richard Cordaux, Clément Gilbert","doi":"10.1016/j.cois.2025.101452","DOIUrl":"10.1016/j.cois.2025.101452","url":null,"abstract":"<div><div>Meiotic drive systems are selfish genetic elements that subvert Mendelian inheritance in favor of their own transmission, often at the expense of host fitness. These elements can lead to profound evolutionary consequences by instigating genetic conflicts, particularly on sex chromosomes, where they frequently reside. Their preferential transmission can distort sex ratios and impact the fertility of carriers, triggering the rapid evolution of suppressor elements, resulting in an evolutionary arms race. This review highlights the dynamic interplay between meiotic drive and sex chromosome evolution, noting that drivers are often linked to recombination-suppressed regions and may catalyze chromosomal divergence and even speciation. Additionally, meiotic drivers can influence reproductive traits and sexual selection. They can reduce male fertility by destroying specific gametes, prompting compensatory adaptations. The reciprocal influence of sexual selection and reproductive behavior on driver frequency underscores the complex nature of this interaction. Though drivers can promote speciation by fixing incompatibilities or facilitating chromosomal rearrangements, they may also act as a stabilizing force, preserving ancestral karyotypes and delaying reproductive isolation. Ultimately, meiotic drive represents a potent evolutionary force shaping genome structure, reproduction, and diversification. Future work integrating molecular, ecological, and evolutionary frameworks is crucial to elucidate the multifaceted roles of meiotic drive across taxa.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101452"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145312535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent insights in the development and functions of insect hemocytes 昆虫血细胞发育和功能的最新研究进展。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-09-15 DOI: 10.1016/j.cois.2025.101434

Michael R Strand

引用次数: 0

Leveraging DNA repair mechanisms in genetically engineered biocontrol 利用基因工程生物防治中的DNA修复机制。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-09-18 DOI: 10.1016/j.cois.2025.101437

Joseph S Romanowski , Christian E Ogaugwu , Zach N Adelman

引用次数: 0

Metabolic command centers in Drosophila: how the fat body and oenocytes orchestrate immunity, reproduction, and aging 果蝇的代谢指挥中心：脂肪体和卵泡细胞如何协调免疫、繁殖和衰老。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-11-09 DOI: 10.1016/j.cois.2025.101459

Kerui Huang , Norbert Perrimon

引用次数: 0

The Drosophila larval salivary gland, a simple and elegant model system to understand secretory organ development and function 果蝇幼虫唾液腺，一个了解分泌器官发育和功能的简单而优雅的模型系统。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-09-17 DOI: 10.1016/j.cois.2025.101435

Ji Hoon Kim, Ashleigh M Shoemaker, Katherine A Hutchings, Sagarika Shinde, Deborah J Andrew

{"title":"The Drosophila larval salivary gland, a simple and elegant model system to understand secretory organ development and function","authors":"Ji Hoon Kim, Ashleigh M Shoemaker, Katherine A Hutchings, Sagarika Shinde, Deborah J Andrew","doi":"10.1016/j.cois.2025.101435","DOIUrl":"10.1016/j.cois.2025.101435","url":null,"abstract":"<div><div>Understanding how cells are specified and subsequently undergo the morphological and physiological specializations required to build functional organs has long been a goal of developmental biology studies. The Drosophila salivary gland (SG), a simple epithelial tubular organ specialized for secretion, has proven an excellent model for understanding how the complex process of organogenesis is orchestrated. The transcription factors (TFs) and signaling pathways that determine where in the developing embryo SGs form and how many cells contribute to each of the specialized cell types have been discovered. The early-expressed downstream SG TFs have been shown to regulate their own and each other’s expression and to also activate downstream target genes directly linked to the mechanical forces of tube morphogenesis and/or to secretory function. Indeed, recent discoveries reveal that the larval SG, long considered an excellent model for exocrine secretion, also functions as an endocrine organ to support overall animal growth, and undergoes massive apocrine secretion as its final act to protect the developing pupa from microbial infection.</div></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"73 ","pages":"Article 101435"},"PeriodicalIF":4.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145091273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of insulin and octopamine in regulating energy homeostasis and locomotion in insects 胰岛素和章鱼胺在调节昆虫能量稳态和运动中的作用。

IF 4.8 1区农林科学

Current opinion in insect science Pub Date : 2026-02-01 Epub Date: 2025-11-04 DOI: 10.1016/j.cois.2025.101457

Rituja S Bisen, Sander Liessem, Martina Held, Jan M Ache

引用次数: 0