{"title":"Impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000371","DOIUrl":"https://doi.org/10.15761/DOMR.1000371","url":null,"abstract":"In the current paper, impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells are studied. After diagnosis the primary treatment for solid tumors is often surgery. The objective of surgical treatment is resection of all malignant tissue with adequate resection margins while preserving important healthy structures. Achieving adequate surgical margins is important for disease control and survival. Residual tumor after surgery is associated with poor survival and the need for additional surgery, adjuvant chemotherapy, radiation therapy, or impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. A number of studies have shown that the 5–year survival decreases significantly when impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. Intraoperative guidance tools can help to achieve adequate surgery. However, there are no widely used intraoperative guidance tools available yet. Current surgical resection techniques are based on subjective methods, such as palpation and visual inspection, to judge the border between normal and cancerous tissue. line of a multi–state DNA/RNA ligand binding","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82389937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional treatment of maxillary hypoplasia and mandibular prognathism","authors":"Ben Younes-Uzan Carine, Benichou Laurence","doi":"10.15761/DOMR.1000349","DOIUrl":"https://doi.org/10.15761/DOMR.1000349","url":null,"abstract":"The first case is a 5 years 8 months old Antillean girl, presenting an articulated complete cross-bite of the whole arch (Figure 1). The maxilla is hypoplastic in the anteroposterior and transverse directions, without any lateral deviation of the mandible, the overbite is reversed but normal in quantity. This is at primary teeth stage, without any diastemas, the lower teeth are tipped lingually to try to compensate for the discrepancy.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1081 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76702141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pros and cons of the roentgenium nanoparticles for human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000316","DOIUrl":"https://doi.org/10.15761/domr.1000316","url":null,"abstract":"In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Roentgenium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [28-74]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Roentgenium nanoparticles are investigated. Abstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78651380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing the accuracy of two electronic apex locators in the determination of working length and the detection of root perforations: An in vitro study","authors":"K. Nasiri, K. Wrbas","doi":"10.15761/docr.1000301","DOIUrl":"https://doi.org/10.15761/docr.1000301","url":null,"abstract":"Aim: To determine the accuracy of two electronic apex locators in measuring working length and detecting the location of root perforations. Methodology: A total of 30 distal roots of extracted first maxillary molars were chosen. The actual working length was first measured. The electronic working length was obtained with Root ZX and Raypex 6. The differences between electronic working lengths and actual working length were calculated. Afterwards, the same roots were perforated artificially above the apical foramen. Both devices were utilized to locate perforations in the distal roots. Subsequently, the obtained measurements were compared. Intraoral environment was simulated employing a fixation device. Data were analysed using repeated measures ANOVA, paired sample t test, chi square, and Fisher exact tests. Statistical significance was considered at the 0.05 level. Results: There was no significant difference among electronic working lengths, measured with the two devices, and actual working length (p>0.05). The percentage of accuracy of electronic working lengths, measured by Root ZX and Raypex 6, was 85.7% and 90.9% respectively within a tolerance of ±0.5 mm (p>0.05). Moreover, the difference between the devices was significant with regard to the location of root perforations (p<0.05). Conclusions: Both electronic apex locators were able to determine canal length. Raypex 6 was more accurate than Root ZX in locating root perforations. *Correspondence to: Kaveh Nasiri, DDS, MSc (Endodontics), Department of Endodontics, Center for Operative Dentistry and Periodontology, University of Dental Medicine and Oral Health, Danube Private University, Krems, Austria, E-mail: DDS.Nasiri@web.de","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91195616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruby Dwivedi, Rahul Pandey, D. Mehrotra, S. Chandra, D. Parmar
{"title":"PRAME pathway in oral carcinogenesis: A systematic review","authors":"Ruby Dwivedi, Rahul Pandey, D. Mehrotra, S. Chandra, D. Parmar","doi":"10.15761/docr.1000297","DOIUrl":"https://doi.org/10.15761/docr.1000297","url":null,"abstract":"High morbidity and mortality associated with oral cancers and its high incidence and prevalence necessitates earlier diagnosis and effective management. Despite of ease in morphological accessibility, oral cancers are still diagnosed mostly in advanced stages chiefly due to lack of effective and cheap screening tools.The search of a suitable biomarker, which can diagnose, oral cancer effectively and can predict the progression of Oral Potentially malignant Disorders (OMPD) to Oral Cancer with accuracy, still exists. PRAME (Preferentially Expressed Antigen of Melanoma) is one such biomarker, which is a dominant repressor of Vitamin A (Vit A). Vit A, chiefly Retinoic Acid (RA) is extensively used these days for chemoprevention owing to its role in cell growth and differentiation. RA emerged as a cheap and acceptable chemo preventive agent since RA is readily available in the form of Vit A food supplements, Vit A is being used in patients with various grades of OPMDs and oral cancer, but its efficiency is still debatable owing to its mixed results in various cancers. Inconsistency in efficient results led to study of various molecules like PRAME, which is involved in RA metabolic pathway thereby modulating the outcome and efficacy of Retinoic Acid chemoprevention. *Correspondence to: Rahul Pandey, Scientist, DHR-MRU,King George Medical University, Lucknow226003, U.P, India, Tel: 9889175042; E-mail: pandey.rahul.dr@gmail.com","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78045962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Simulation of interaction between ytterbium nanoparticles and human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000311","DOIUrl":"https://doi.org/10.15761/domr.1000311","url":null,"abstract":"In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Ytterbium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [2874]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Ytterbium nanoparticles are investigated. Abstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88461689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maitotoxin time–resolved absorption and resonance FT–IR and raman biospectroscopy and density functional theory (DFT) investigation of vibronic–mode coupling structure in vibrational spectra analysis: a spectroscopic study on an anti–gum cancer drug","authors":"A. Heidari, J. Esposito, Angela Caissutti","doi":"10.15761/domr.1000318","DOIUrl":"https://doi.org/10.15761/domr.1000318","url":null,"abstract":"Gum cancers are cancers that arise from the gum. They are due to the development of abnormal cells that have the ability to invade or spread to other parts of the body. There are three main types of gum cancers: basal-cell gum cancer (BCC), squamous-cell gum cancer (SCC) and melanoma. Batrachotoxin (BTX) is an anti-gum cancer extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. Batrachotoxin was derived from the Greek word βάτραχος bátrachos \"frog\". StructurallyAbstract","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"64 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84738629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Ambayiram, A. Chidembaranathan, Muthukumar Balasubramanium
{"title":"Coping retained removable partial denture an alternative to fixed partial denture: A case report","authors":"A. Ambayiram, A. Chidembaranathan, Muthukumar Balasubramanium","doi":"10.15761/docr.1000298","DOIUrl":"https://doi.org/10.15761/docr.1000298","url":null,"abstract":"Overdenture therapy is a kind of preventive prosthodontics treatment modality that preserves the remaining natural teeth and roots. The periodontal membrane with its proprioceptive mechanism can be preserved by the overdenture therapy. This case report presents a tooth supported removable partial denture which influence esthetics and improved function. *Correspondence to: S C Ahila, Associate Professor, Department of Prosthodontics, SRM Dental College, Ramapuram, Chennai-89, India, Tel: 9443607653, E-mail: ahilasc@yahoo.co.in","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90988573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug delivery systems (DDSs) of osmium nanoparticles on human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000325","DOIUrl":"https://doi.org/10.15761/domr.1000325","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Osmium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Osmium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Osmium nanoparticles by solving heat equation. The obtained results show that Osmium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. image of Osmium nanoparticles with 50000x","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89778523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hafnium nanoparticles and their roles and applications in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000320","DOIUrl":"https://doi.org/10.15761/domr.1000320","url":null,"abstract":"*Correspondence to: Alireza Heidari, Faculty of Chemistry, California South University, 14731 Comet St. Irvine, CA 92604; American International Standards Institute, Irvine, CA 3800, USA, E-mail: Scholar.Researcher.Scientist@gmail.com; Alireza.Heidari@calsu.us; Central@aisi-usa.org","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80545450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}