Simulation of interaction between ytterbium nanoparticles and human gum cancer cells, tissues and tumors treatment under synchrotron radiation

A. Heidari, K. Schmitt, M. Henderson, E. Besana
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引用次数: 20

Abstract

In recent decade, metallic nanoparticles have been widely interested due to their interesting optical characteristics [1-8]. Resonances of surface Plasmon in these nanoparticles lead to increase in synchrotron radiation emission as a function of the beam energy scattering and absorption in related frequency [9,10]. Synchrotron radiation emission as a function of the beam energy absorption and induced produced heat in nanoparticles has been considered as a side effect in plasmonic applications for a long time [11-15]. Recently, scientists find that thermoplasmonic characteristic can be used for various optothermal applications in cancer, nanoflows and photonic [16-22]. In optothermal human cancer cells, tissues and tumors treatment, the descendent laser light stimulate resonance of surface Plasmon of metallic nanoparticles and as a result of this process, the absorbed energy of descendent light converse to heat in nanoparticles [23-25]. The produced heat devastates tumor tissue adjacent to nanoparticles without any hurt to sound tissues [26,27]. Regarding the simplicity of ligands connection to Ytterbium nanoparticles for targeting cancer cells, these nanoparticles are more appropriate to use in optothermal human cancer cells, tissues and tumors treatment [2874]. In the current paper, thermoplasmonic characteristics of spherical, core-shell and rod Ytterbium nanoparticles are investigated. Abstract
同步辐射下纳米镱粒子与人牙龈癌细胞、组织和肿瘤治疗相互作用的模拟
近十年来,金属纳米颗粒因其有趣的光学特性而受到广泛关注[1-8]。这些纳米颗粒表面等离子体的共振导致同步辐射发射的增加,这是光束能量散射和相关频率吸收的函数[9,10]。长期以来,同步辐射发射作为粒子束能量吸收和诱导产生热的函数一直被认为是等离子体应用中的一个副作用[11-15]。最近,科学家们发现热等离子体特性可用于癌症、纳米流和光子等各种光热应用[16-22]。在光热治疗人类癌细胞、组织和肿瘤中,激光的入射光激发金属纳米粒子表面等离子体共振,从而使入射光吸收的能量转化为纳米粒子中的热量[23-25]。产生的热量摧毁纳米颗粒附近的肿瘤组织,而不会对正常组织造成任何伤害[26,27]。由于配体与靶向癌细胞的镱纳米颗粒连接简单,因此这些纳米颗粒更适合用于光热治疗人类癌细胞、组织和肿瘤[2874]。本文研究了球形、核壳和棒状镱纳米粒子的热等离子体特性。摘要
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