Dental, Oral and Maxillofacial Research最新文献

{"title":"New opportunities for tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000374","DOIUrl":"https://doi.org/10.15761/DOMR.1000374","url":null,"abstract":"In the current study, new opportunities for tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells are investigated. Tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells originates initially from analytical chemistry to evaluate chemical compounds based on varied excitation of vibrational modes in the internal chemical bonds. Since tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells is able to detect tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells signals from the bonds within molecules, it can also provide the biochemical conditions within biological samples. Within a molecularly complicated biological system, like a cell, tissue or even an organ, tensor–free calculations of residual dipolar couplings for the study of dynamic nuclear polarization of nucleic acids with endogenously bound manganese in gum cancer cells carries intrinsic details and information of the materials present in the system, thus the biological status can also be acquired based on which the detailed features of the tissue are easily and accurately obtained.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77404096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A soft-tissue vertical line to research the profile harmony","authors":"F. Ciuffolo","doi":"10.15761/DOMR.1000361","DOIUrl":"https://doi.org/10.15761/DOMR.1000361","url":null,"abstract":"The anterior-posterior position of upper incisor is a determinant of the ideal soft-tissue profile [1]. For this reason, from the beginning of our specialty, “the profile with perfect harmony” was researched [2] and different analysis have been described for this purpose [1-5]. Since many variables have been used to analyse the ideal soft tissue profile, the aim of this clinical paper is to describe and propose an easy and quick analysis to establish the anterior-posterior position of upper incisor in relation to the soft-tissue profile, by using two lines and two soft-tissue landmarks.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78472278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000369","DOIUrl":"https://doi.org/10.15761/DOMR.1000369","url":null,"abstract":"In the current study, advanced isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR are investigated. Since the middle of 20(th) century isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy has been recognized as a non–destructive, label free, highly sensitive and specific analytical method with many potential useful applications in different fields of biomedical research and in particular gum cancer research and diagnosis. Although many technological improvements have been made to facilitate biomedical applications of this powerful analytical technique, it has not yet properly come into the scientific background of many potential end users. Therefore, to achieve those fundamental objectives an interdisciplinary approach is needed with basic scientists, spectroscopists, biologists and clinicians who must effectively communicate and understand each other’s requirements and challenges. In this review we aim at illustrating some principles of isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy as a useful method to interrogate molecules in specimen by isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti– cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy. Penetrating into basics of molecular vibrations might help us to understand whether, when and how complementary information obtained by isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy could become useful in our research and/or diagnostic activities. isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy allowing to acquire information about the molecular composition and structure of a sample within a micrometric scale in a matter of seconds will be illustrated as well as some limitations will be discussed. How biochemical, structural, and dynamical information about the systems can be obtained by bench top isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for production of isotope–labeled DNA/RNA in gum cancer cells for NMR spectroscopy instrumentation will be also presented together with some methods to treat and interpret isotopic labeling for the NMR investigation of challenging DNA/RNA of gum cancer cells and anti–cancer Nano drugs for product","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"299 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90215542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The validity of oral prosthetic stents for maxillofacial cancer during radiation therapy: Case report","authors":"K. Nam","doi":"10.15761/domr.1000336","DOIUrl":"https://doi.org/10.15761/domr.1000336","url":null,"abstract":"Radiation prosthetic stents are the customized oral devices fabricated for efficient administration of radiation dose to the affected areas or minimizing the unnecessary irradiation to surrounding normal tissues on head and neck neoplasms. Since the use of these stents is individualized, a close collaboration among surgeon, radiotherapist and prosthodontist is essential thereby which helps in limiting the post-therapy morbidity. In this report, two customized stents, tissue bolus and tongue depressing type were successfully applied to patients who were under RT plan due to soft palate cancer and tongue carcinoma respectively.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76703020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of anti–cancer nano drugs particles (ACNDP) to NMR characterization of viral gum cancer cell membrane DNA/RNA interactions for extracting DNA/RNA dynamics information from overlapped NMR signals using relaxation dispersion difference NMR spectroscopy","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000372","DOIUrl":"https://doi.org/10.15761/DOMR.1000372","url":null,"abstract":"In the current investigation, application of anti–cancer Nano drugs particles (ACNDP) to NMR characterization of viral gum cancer cell membrane DNA/RNA interactions for extracting DNA/RNA dynamics information from overlapped NMR signals using relaxation dispersion difference NMR spectroscopy are studied. NMR spectroscopy can also give an objective and reliable decision about malignancy and early malignant stages of anti–cancer Nano drugs particles (ACNDP) to NMR characterization of viral gum cancer cell membrane DNA/RNA interactions for extracting DNA/RNA dynamics information from overlapped NMR signals using relaxation dispersion difference NMR spectroscopy. This technique could help medical professionals in assessing with a clinically relevant specificity and sensitivity the location for most representative biopsies.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"74 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81272149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential in the elimination of cancer cells through synchrotron radiation: A hartree-fock methods analysis protonated rhodochrosite crystal","authors":"R. Gobato, Marcia Regina Risso Gobato, A. Heidari, A. Mitra","doi":"10.15761/DOMR.1000352","DOIUrl":"https://doi.org/10.15761/DOMR.1000352","url":null,"abstract":"The rhodochrosite (MnCO3) shows complete solid solution with siderite (FeCO3), and it may contain substantial amounts of Zn, Mg, Co, and Ca. There is no precedent in the literature on the treatment of tumor tissues by eliminating these affected tissues, using rhodocrosite crystals in tissue absorption and eliminating cancerous tissues by synchrotron radiation. The studies that are found are the research papers of this team. Through an unrestricted Hartree-Fock (UHF) computational simulation, Compact effective potentials (CEP), the infrared spectrum of the protonated rhodochrosite crystal, CH19Mn6O8, and the load distribution by the unit molecule by two widely used methods, Atomic Polar Tensor (APT) and Mulliken, were studied. The rhodochrosite crystal unit cell of structure CMn6O8, where the load distribution by the molecule was verified in the UHF CEP-4G (Effective core potential (ECP) minimal basis), UHF CEP-31G (ECP split valance) and UHF CEP-121G (ECP triple-split basis). The largest load variation in the APT and Mulliken methods were obtained in the CEP-121G basis set, with δ = 2.922 e δ = 2.650 u. a., respectively, being δAPT > δMulliken. The maximum absorbance peaks in the CEP-4G, CEP-31G and CEP-121G basis set are present at the frequencies 2172.23 cm-1, with a normalized intensity of 0.65; 2231.4 cm-1 and 0.454; and 2177.24 cm-1 and 1.0, respectively. An in-depth study is necessary to verify the absorption by the tumoral and non-tumoral tissues of rhodochrosite, before and after irradiating of synchrotron radiation using Small–Angle X–Ray Scattering (SAXS), Ultra–Small Angle X–Ray Scattering (USAXS), Fluctuation X–Ray Scattering (FXS), Wide–Angle X–Ray Scattering (WAXS), Grazing–Incidence Small–Angle X–Ray Scattering (GISAXS), Grazing–Incidence Wide–Angle X–Ray Scattering (GIWAXS), Small–Angle Neutron Scattering (SANS), Grazing–Incidence Small–Angle Neutron Scattering (GISANS), X–Ray Diffraction (XRD), Powder X–Ray Diffraction (PXRD), Wide–Angle X–Ray Diffraction (WAXD), Grazing– Incidence X–Ray Diffraction (GIXD) and Energy–Dispersive X–Ray Diffraction (EDXRD). Later studies could check the advantages and disadvantages of rhodochrosite in the treatment of cancer through synchrotron radiation, such as one oscillator crystal. Studying the sites of rhodocrosite action may lead to a better understanding of its absorption by healthy and/or tumor tissues, thus leading to a better application of synchrotron radiation to the tumors to eliminate them.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85995709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classification of drug delivery system of niobium nanoparticles in human gum cancer gum cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/domr.1000330","DOIUrl":"https://doi.org/10.15761/domr.1000330","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Niobium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Niobium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Niobium nanoparticles by solving heat equation. The obtained results show that Niobium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. Scanning Electron Microscope image of Niobium nanoparticles with 50000x zoom. Spectroscopy, Macro–Attenuated Total Reflectance Fourier Transform Infrared (Macro–ATR– FTIR) Spectroscopy, Two–Dimensional Infrared Correlation Spectroscopy, Linear Two–Dimensional Infrared Spectroscopy, Non–Linear Two–Dimensional Infrared Spectroscopy, Atomic Force Microscopy Based Infrared (AFM–IR) Spectroscopy, Infrared Photodissociation Spectroscopy, Infrared Correlation Table Spectroscopy,","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85379451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the use of mouthwash before collecting saliva specimen increase the possibility of a false-negative result in COVID-19 testing?","authors":"K. Nasiri, A. Dimitrova, Kamyar Nasiri","doi":"10.15761/DOMR.1000360","DOIUrl":"https://doi.org/10.15761/DOMR.1000360","url":null,"abstract":"A complex bio-fluid, saliva is secreted by major and minor salivary glands in the oral cavity. It is composed of protein and peptides, hormones, antibodies, and other molecular components, which are helpful for the examination of the physiological and pathological conditions of the human body. Saliva is currently used for the detection of different types of cancer, including oral, breast, and lung cancer, periodontal diseases, diabetes, and acute respiratory syndrome. It is, indeed, considered as a diagnostic window for various pathological diseases [1,2].","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87453406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive image-guided targeted drug delivery of radium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000348","DOIUrl":"https://doi.org/10.15761/DOMR.1000348","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Radium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radium nanoparticles by solving heat equation. The obtained results show that Radium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of with","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82796273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unprecedented progresses of biomedical nanotechnology during conventional smart drug delivery systems (SDDSs) of francium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation","authors":"A. Heidari, K. Schmitt, M. Henderson, E. Besana","doi":"10.15761/DOMR.1000347","DOIUrl":"https://doi.org/10.15761/DOMR.1000347","url":null,"abstract":"In the current study, thermoplasmonic characteristics of Francium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Francium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Francium nanoparticles by solving heat equation. The obtained results show that Francium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method.","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"876 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82200730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}